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Injuries from motor vehicle crashes are the leading cause of mortality
in children aged 5 years and older in the United States. This review
discusses common injuries in children after motor vehicle trauma
and examines the evidence regarding the evaluation and treatment
of pediatric patients involved in motor vehicle crashes. Both prehospital and emergency department care are discussed along with a
differential diagnosis of the injuries most commonly seen in motor
vehicle crashes. The various options for imaging modalities are also
discussed in this review. A critical appraisal of the existing guidelines for the management of motor vehicle trauma and for the use of
appropriate child-safety restraints is presented. Emergency clinicians
will be able to use the patients history and physical examination
findings along with knowledge of common injuries to determine the
most appropriate workup and treatment of pediatric patients who
present with motor vehicle trauma.
Editor-in-Chief
August 2013
Christopher Strother, MD
Assistant Professor, Director,
Undergraduate and Emergency
Emergency Medicine, University of
Simulation, Mount Sinai School of
Florida, Jacksonville, FL
Medicine, New York, NY
International Editor
Lara Zibners, MD, FAAP
Honorary Consultant, Paediatric
Emergency Medicine, St Mary's
Hospital, Imperial College Trust;
EM representative, Steering Group
ATLS-UK, Royal College of
Surgeons, London, England
Pharmacology Editor
James Damilini, PharmD, MS,
BCPS
Clinical Pharmacy Specialist,
Emergency Medicine, St.
Joseph's Hospital and Medical
Center, Phoenix, AZ
Case Presentations
You receive a call that an 8-year-old child who was in a
motor vehicle crash will be arriving by air transport in
8 minutes. The child was the unrestrained passenger in
the back seat of a sport utility vehicle that was involved
in a high-speed collision on a busy freeway. The child was
ejected from the vehicle. When EMS arrived on scene, the
child was lying on the side of the road and was moaning
in pain. He was noted to have abrasions on his abdomen
and swelling of his left thigh. En route to the hospital, the
childs heart rate was 115 beats/min, respiratory rate was
24 breaths/min, and blood pressure was 90/42 mm Hg.
While you are waiting in the trauma bay for the patient,
you consider the injuries for which he is at risk and the
interventions, laboratory studies, and radiographic studies he may require.
A 14-year-old girl is brought in by ambulance after a
motor vehicle crash. She was a restrained passenger in the
front seat of a car driven by her mother. When the car in
front of them stopped suddenly, the patients car slammed
into it and was then rear-ended by the car behind theirs.
She was wearing both her lap and shoulder restraints, and
there was no airbag deployment, passenger space intrusion, or damage to the windshield or windows. The girl
denied any head injury or loss of consciousness. The girl
was ambulatory at the scene, but when EMS arrived, she
was placed in a cervical collar, positioned on a backboard,
and brought to the ED. On arrival, she is alert and oriented but is complaining of neck and back pain. She has
no other associated injuries. You wonder whether the patients cervical collar and backboard can be safely removed
and what, if any, radiographic studies you should order.
An ambulance arrives with a 3-year-old girl who
was involved in a pedestrian-versus-automobile accident.
The child was playing in the front yard of her familys
home when the ball she was playing with rolled onto
the driveway. She ran out to grab the ball just as her
father was backing his car out of the driveway; he felt a
thump as he backed over her. He immediately got out
of the car and found his daughter lying on the driveway
underneath the car between the front and rear wheels,
crying. An ambulance was called, and the child was
placed in a cervical collar and positioned on a backboard
and brought to the ED. On arrival, the child is alert and
awake with a Glasgow Coma Scale score of 15. Her head
and neck examination is within normal limits, but she
appears to have some abdominal tenderness and bruising
on the lower portion of her abdomen. As you complete the
remainder of your examination, you consider the injuries
for which this patient is at risk, based on her mechanism
of injury, and decide which imaging studies to order.
Introduction
Motor vehicle crashes (MVCs) are the leading cause
of morbidity and mortality among children in the
United States, and they often present a diagnostic
Pediatric Emergency Medicine Practice 2013 2
cerebral edema, and concussions. The precise incidence of each of these injury types is unknown, but
all must be considered when evaluating a patient in
the emergency department (ED).
Skull Fracture
MVC patients who have sustained skull fractures
(such as linear skull fractures or depressed skull
fractures) typically present with large scalp hematomas, palpable step-offs, or bony deformities. Basilar
skull fractures, on the other hand, often present with
characteristic physical examination findings such
as Battle sign (the presence of posterior auricular or
mastoid hematomas), hemotympanum or bleeding
from the ear canal, cerebrospinal fluid otorrhea or
rhinorrhea, periorbital ecchymoses ("raccoon eyes"),
or cranial nerve palsies.36-39 However, given that
these are late findings, their absence does not rule
out a basilar skull fracture. Unlike other types of
skull fractures, basilar skull fractures are frequently
associated with intracranial injury even in patients
with a GCS score of 15 and a normal neurologic
examination.36 Although the precise incidence of
basilar skull fractures in pediatric patients involved
in MVCs is unknown, both MVCs and pedestrianversus-automobile accidents are common mechanisms of injury for these types of fractures.37
Intracranial Injury
Intracranial injuries can be divided into 2 primary
categories: (1) focal lesions such as epidural, subdural, or intraparenchymal hematomas, and (2) diffuse
injuries such as cerebral edema or diffuse axonal
injury.40 Physical examination findings concerning
for intracranial hemorrhage include altered level
of consciousness on arrival or any focal neurologic
findings on examination.36,40 Although the prevalence of these injuries is low in a child with a normal
neurologic examination (including a GCS score of 14
or 15), the consequences can be devastating if they
are missed. Diffuse axonal injury is a generalized
intracranial injury that occurs primarily as a result
of acceleration and deceleration forces. Although the
precise incidence of diffuse axonal injury in pediatric
MVCs is unknown, previous studies have estimated
that it occurs in up to 40% of children with severe
traumatic brain injury. With increasing use of magnetic resonance imaging (MRI), these injuries can
now be more accurately diagnosed, whereas they
may have been missed in the past.36,41
Differential Diagnosis
Head Injury
have abnormalities on MRI, sparking debate regarding whether these patients should truly be classified
as having SCIWORA.43,58 Children with clinical
findings concerning for SCIWORA should undergo
imaging with MRI. MRI can also be used to identify
ligamentous injuries in patients with continued pain
or persistent neurologic symptoms.
Abdominal Injury
trauma. The severity of splenic injuries is classified into grades ranging from I to V based on the
American Association for the Surgery of Trauma
guidelines.65,67 (See Figure 1.) As with hepatic injury,
mortality increases with increasing grades of splenic
injury.65 Classic physical examination findings
include diffuse or left upper quadrant abdominal
pain and the presence of the Kehr sign, which is left
shoulder pain caused by irritation of the diaphragm
from free intra-abdominal fluid.64,66
Renal Injury
Renal injury is the third most common solid organ
injury in children after blunt abdominal trauma,
with motor vehicle trauma as the most common
cause of renal injury. Children are more susceptible
to renal trauma than adults because of their weaker
abdominal musculature, more compliant rib cage,
and decreased perirenal fat.68,69 Common renal injuries after blunt trauma include contusions, lacerations, and hematomas, which are graded from I to V
based on severity.65 (See Figure 1.) Increasing grades
of injury severity are associated with increasing mortality.65 Characteristic physical examination findings
in renal trauma overlap with those of hepatic and
splenic injuries and include abdominal tenderness
and hematuria.68-70
Thoracic Injury
Prehospital Care
Prehospital providers play an essential role in the
management of pediatric trauma and can have a
significant impact on the outcomes of these patients.
The primary goals of the prehospital provider are:
(1) to identify the patients with the most severe injuries and injuries with the potential to result in rapid
decompensation of the patient, and (2) to transport
these patients safely and quickly to the nearest
Pediatric Emergency Medicine Practice 2013 6
this imaging technique is less well studied for hemothoraces.98-100 Performance of the eFAST should
not delay needle decompression if the patient has a
critical presentation.
As with the assessment of circulation in the
field, patients without evidence of spontaneous
circulation should be managed utilizing PALS algorithms, while patients with uncontrolled external
hemorrhage will require temporizing measures such
as application of direct pressure or a tourniquet to
stop the bleeding. Patients with uncontrolled internal hemorrhage who cannot be stabilized may require immediate surgical intervention. A GCS score
should be calculated as part of the assessment of
disability, and the patient should be fully exposed,
with clothing removed to facilitate the secondary
survey. The child should be covered with sheets or
blankets as soon as possible to prevent hypothermia.
This entire process should be performed with a rigid
cervical collar and triple immobilization or with
manual inline immobilization of the cervical spine
while the patient remains on the backboard.
Primary Survey
As part of the primary survey, the airway, breathing, and circulation should be thoroughly assessed.
The first step in the evaluation of any patient is to
assess the patency of the airway and to secure the
airway as soon as possible, if necessary. As with
patients in the field, basic airway maneuvers (such
as a jaw-thrust maneuver and ventilation with a bag
mask) should always be attempted on patients with
evidence of airway compromise before moving on to
more advanced airway techniques. Patients without
airway compromise should be given supplemental
oxygen. A definitive airway (such as a cuffed endotracheal tube) should be placed as soon as possible
in patients requiring such an intervention while
maintaining inline cervical immobilization. The position of the endotracheal tube should be confirmed
by auscultation of bilateral breath sounds and endtidal carbon dioxide (ETCO2) tracing.
In some trauma patients (such as those with significant facial trauma), endotracheal intubation may
not be possible. In these patients, airway adjuncts
such as intubation with a video laryngoscope or
placement of laryngeal-mask airway may be required as a temporizing measure prior to insertion
of a definitive airway. If none of these maneuvers
are successful, a needle cricothyroidotomy may be
required for oxygenation until a more definitive
airway can be established. A surgical cricothyroidotomy should generally not be performed in children under 10 to 12 years of age because of the risk
of damaging the cricoid cartilage and surrounding
structures and potentially causing further airway
compromise.94,95 In prepubescent children, the tracheal cartilages are very soft and pliable and provide
minimal support to the upper airway. As a result,
the cricoid cartilage is the only circumferential support for the trachea, and it is the primary structure
responsible for maintaining airway patency.95 Additionally, children who undergo surgical cricothyroidotomy are at increased risk for the development
of subglottic stenosis as they grow older.96,97
Once an airway is established, the presence of
equal bilateral breath sounds should be confirmed.
In patients with diminished or absent breath sounds,
the possibility of either a tension pneumothorax or
a massive hemothorax should be considered, and,
if confirmed, needle decompression and/or placement of a chest tube should be performed. Diagnosis
of a pneumothorax can be confirmed with bedside
ultrasound in the form of the extended focused abdominal sonography for trauma (eFAST), although
August 2013 www.ebmedicine.net
Secondary Survey
Clinical History
Diagnostic Studies
One of the challenges in evaluating pediatric patients presenting after motor vehicle trauma is determining the most appropriate laboratory and radiologic workup. Although a variety of laboratory and
radiologic studies exist, it is important to undertake
this workup in a methodical fashion such that all
clinically significant injuries are identified without
unnecessary laboratory or radiographic testing.
Laboratory Studies
Although many pediatric patients undergo laboratory testing on arrival to the ED, a standardized
trauma panel does not exist, and the use of one is
not recommended. Instead, a variety of laboratory
studies are often ordered, depending on the institution where the patient is receiving care. Among
the tests that are frequently ordered are a complete
blood count (CBC), a blood type and crossmatch,
serum aspartate aminotransferase (AST) and serum
alanine aminotransferase (ALT), urinalysis, prothrombin time (PT), and partial thromboplastin
time (PTT).103
Detection Of Occult Hemorrhage
The preferred diagnostic study for the detection of
hemorrhage or other forms of occult injury is serial
hematocrits. Although there is minimal pediatric
literature on the subject, the utility of serial hematocrits has been demonstrated in adult populations. Serial hematocrits are a reliable indicator
for ongoing blood loss and major injury, although
the absence of a hematocrit drop cannot be used
to exclude major injury.104-106 Based on these data
in adults, serial hematocrits may be helpful in the
detection of internal hemorrhage in children. A type
and crossmatch should also be ordered in patients
with hemorrhage in whom a blood transfusion may
be required. Critically hemorrhaging children can always receive O-negative blood products, but proper
crossmatching may minimize overuse of the local
O-negative supply.
Detection Of Intra-Abdominal Injury
Identification of intra-abdominal injury in children
who have sustained blunt abdominal trauma has
remained a challenge for emergency clinicians. Studies have been performed to determine the utility of
specific features of the history and physical examination, along with laboratory studies, as predictors
for intra-abdominal injury. The presence of abdominal tenderness, gross or microscopic hematuria,
abdominal wall bruising, abnormal liver function
studies, pelvic fracture, or a history concerning for
assault or abuse have all been shown to be associated with intra-abdominal injury.61,66,107,108 Prior
studies have demonstrated that elevated AST and
ALT values can be used to identify children at risk
August 2013 www.ebmedicine.net
Trauma-Induced Coagulopathy
Trauma-induced coagulopathy is a well-known
phenomenon that occurs in trauma patients, particularly those with traumatic brain injury, and it is often
associated with a poor prognosis.114-117 The preferred
laboratory studies for the identification of traumainduced coagulopathy are coagulation studies such
as PT, PTT, and a platelet count. While the precise
etiology of this coagulopathy is unknown, it is likely
multifactorial in origin and related to tissue hypoxia
and acidosis, consumption of coagulation factors
and platelets, increased fibrinolysis, and dysfunction
of the platelet and coagulation system.114,118-121 In the
pediatric population, reported rates of coagulopathy after traumatic brain injury range from 37.9% to
77%.117,122,123 Risk factors for coagulopathy in children after traumatic brain injury include evidence of
significant multisystem trauma, injury severity score
16, the presence of cerebral edema on CT scan, the
presence of chest and/or abdominal injury, and a
low GCS score.122,123 Based on these data, children
who are suspected to have intracranial injury based
on their mechanism of injury, GCS score on arrival,
or physical examination findings should have a
platelet count and coagulation panel drawn as part
of their initial evaluation.
Radiographic Evaluation
Patients must meet all 5 criteria to be classified as low risk for cervical
spine injury. This decision rule has a sensitivity of 99% and a specificity of 12.9%.
Abbreviation: NEXUS, National Emergency X-Radiography Utilization
Study.
Reprinted from Annals of Emergency Medicine, Volume 32, Issue 4.
Jerome R. Hoffman, Allan B. Wolfson, Knox Todd, et al. Selective cervical spine radiography in blunt trauma: methodology of the National
Emergency X-Radiography Utilization Study (NEXUS). Pages 461-469.
Copyright 1998, with permission from Elsevier.
11
Treatment
The first goal of treatment in the ED is to identify
and treat conditions that will lead to rapid deterioration of the patient, such as airway obstruction,
respiratory failure, tension pneumothoraces, massive hemothoraces, cardiac tamponade, or uncontrolled hemorrhage.148 All of these conditions require
emergent procedural interventions (such as endotracheal intubation, needle cricothyroidotomy, needle
decompression, tube thoracostomy, or pericardiocentesis), and they should be identified and initially
managed during the primary survey.148,149
While the primary survey is being performed,
it is crucial that reliable vascular access in the form
of an intravenous line, intraosseous line, or central
venous catheter is obtained for the administration
of intravenous fluids, blood products, and medications. Peripheral intravenous lines and intraosseous
lines are preferred over central venous catheters,
given the time it takes to place a central venous
catheter. In a hemodynamically unstable child, an
intraosseous line should be placed after 2 unsuccessful intravenous attempts. Rapid administration
of intravenous fluid in the form of warmed normal
saline or lactated Ringer's solution should be given
to all patients with evidence of shock after blunt
trauma. A total of 3 crystalloid boluses of 20 mL/
kg each should be given, and the patients response
to the fluids should be assessed after each bolus. In
general, children will require a volume of crystalloid fluid equivalent to 3 times the estimated blood
loss.86 While tachycardia is an early sign of hemorrhage, hypotension may not develop until 30% to
45% of blood volume has been lost. Transfusion of
blood products is indicated for patients who only
transiently improve with crystalloid infusions and
should be considered in pediatric patients requiring a third bolus of crystalloids.86
Once these initial steps in the stabilization of
the patient have been completed, whether or not
the patient requires immediate operative intervention must be determined. In the past, many solid
organ injuries to the liver and spleen were managed
operatively. Today, the standard of care for nearly
www.ebmedicine.net August 2013
Although these redesigned second-generation airbags have resulted in decreased fatality and injury
rates when compared to first-generation airbags,
they still remain a significant source of injury. The
most recent airbag safety standards require that all
airbags be tested for all sizes of occupants, including
children, and airbag redesign efforts remain ongoing. Until airbags can be redesigned to assure child
safety, the American Academy of Pediatrics strongly
recommends that all children aged < 13 years should
sit in the rear seats of vehicles. When this is not possible, as in the case of vehicles with a single row of
seats (such as pick-up trucks), front airbags should
be deactivated or turned off.7
Disposition
Special Circumstances
Airbag-Related Injuries In Children
13
YES
Head CT (Class I)
YES
NO
*Severe mechanisms of injury include the following: rollover accident, ejection from a motor vehicle, death of another passenger, or pedestrian or bicyclist without helmet struck by motor vehicle.
Abbreviations: CT, computed tomography; GCS, Glasgow Coma Scale.
Adapted and reprinted from The Lancet, Volume 374. Nathan Kupperman, James F. Holmes, Peter S. Dayan, et al. Identification of children at very low
risk of clinically important brain injuries after head trauma: a prospective cohort study. Pages 1160-1170. Copyright 2009, with permission from Elsevier.
Level of Evidence:
One or more large prospective
studies are present (with rare
exceptions)
High-quality meta-analyses
Study results consistently positive and compelling
Class II
Safe, acceptable
Probably useful
Level of Evidence:
Generally higher levels of
evidence
Non-randomized or retrospective studies: historic, cohort, or
case control studies
Less robust randomized controlled trials
Results consistently positive
Class III
May be acceptable
Possibly useful
Considered optional or alternative treatments
Level of Evidence:
Generally lower or intermediate
levels of evidence
Case series, animal studies,
consensus panels
Occasionally positive results
Indeterminate
Continuing area of research
No recommendations until
further research
Level of Evidence:
Evidence not available
Higher studies in progress
Results inconsistent, contradictory
Results not compelling
Significantly modified from: The
Emergency Cardiovascular Care
Committees of the American
Heart Association and repre-
This clinical pathway is intended to supplement, rather than substitute for, professional judgment and may be changed depending upon a patients individual
needs. Failure to comply with this pathway does not represent a breach of the standard of care.
Copyright 2013 EB Medicine. 1-800-249-5770. No part of this publication may be reproduced in any format without written consent of EB Medicine.
YES
Head CT (Class I)
YES
NO
*Severe mechanisms of injury include the following: rollover accident, ejection from a motor vehicle, death of another passenger, or pedestrian or bicyclist without helmet struck by motor vehicle.
Abbreviations: CT, computed tomography; GCS, Glasgow Coma Scale.
Adapted and reprinted from The Lancet, Volume 374. Nathan Kupperman, James F. Holmes, Peter S. Dayan, et al. Identification of children at very low
risk of clinically important brain injuries after head trauma: a prospective cohort study. Pages 1160-1170. Copyright 2009, with permission from Elsevier.
See class of evidence definitions on page 14.
15
NO
NO
NO
YES
Clinically clear;
discontinue cervical collar (Class II)
YES
Cooperative: anteroposterior/lateral/
odontoid x-rays
Uncooperative: anteroposterior/lateral
x-rays
YES
Clinically clear;
discontinue cervical collar
(Class II)
YES
Is repeat examination
normal?
NO
NO
YES
CT head down to C3 to
rule out injuries to upper
cervical spine (Class II)
YES
NO
NO
ABNORMAL
NORMAL
LEVEL OF
CONSCIOUSNESS
IMPROVING
17
YES
NO
To operating room
for exploratory laparotomy
(Class I)
POSITIVE
NEGATIVE
YES
NO
YES
NO
AST > 200 U/L
or
ALT > 125 U/L
Does the patient have any of the
following?
Thoracic wall trauma
Abdominal pain
Decreased breath sounds
Emesis
YES
NO
Abbreviations: ALT, alanine aminotransferase; AST, aspartate aminotransferase; CT, computed tomography; ED, emergency department; FAST, focused
assessment with sonography in trauma.
Please see class of evidence definitions on page 14.
Case Conclusions
All 3 children are at risk for specific injury types based on
their presenting histories and complaints. Of the 3 patients,
the 8-year-old and the 3-year-old are at greatest risk for
severe injuries based on their mechanisms of injury: ejection from a motor vehicle and pedestrian-versus-automobile
injury in the form of a driveway injury, respectively.
The 8-year-old was hypotensive and tachycardic on
arrival, with abdominal abrasions and swelling of his left
thigh. These findings are concerning for intra-abdominal
injury along with a left femur fracture. Although the
childs airway was patent, he was moaning incoherently
and his GCS was 8 on arrival, so you made the decision
to intubate him with an endotracheal tube. A chest x-ray
and ETCO2 monitoring confirmed position of the endotracheal tube and breath sounds were equal bilaterally.
An emergent head CT did not demonstrate any intracranial hemorrhage. At this point, the childs hypotension
and tachycardia worsened, and you determined that the
most immediate potential threat to life was compromised
circulation secondary to hemorrhage from an intraabdominal injury. A FAST examination was performed,
which demonstrated significant intra-abdominal free
fluid. An unstable intra-abdominal bleed was suspected,
and he was taken immediately to the operating room for
further management.
The 14-year-old girl was complaining of neck and back
pain after a low-speed MVC. Her GCS score on scene was
15, and she was ambulatory. Based on her mechanism of
injury, she was at risk for injuries to the neck and spine.
Her primary survey was within normal limits. Her secondary survey did not demonstrate any tenderness to palpation
of the thoracic or lumbar spine and no step-offs were noted,
so she was removed from the backboard. Her cervical collar
was left in place. Because her mental status was at baseline,
she was not intoxicated, and she did not have any painful
or distracting injuries on your initial examination, she was
a candidate for clinical clearance of the cervical spine. On
your examination, she had no midline cervical tenderness,
had no focal neurologic deficits, and was able to move her
head in flexion, extension, and lateral rotation without
pain, so you were able to clinically clear her cervical spine.
You gave her a dose of ibuprofen for pain and discharged
her home from the ED with instructions to return for new
or worsening symptoms.
Summary
MVCs are a leading cause of morbidity and mortality
among children in the United States. Because of their
unique anatomic considerations and stature, children
are particularly vulnerable to specific injury types
and patterns when involved in MVCs. Unlike adults,
children have relatively large heads, more pliable
thoracic cavities, larger intra-abdominal solid organs,
and less intra-abdominal fat and musculature, all of
which are factors that increase their risk for injury.
One additional issue that arises when treating very
young children is their diminished ability to local-
< 2 years
2 years
19
The 3-year-old who was brought to the ED after a
pedestrian-versus-automobile accident was complaining of abdominal pain. Her vital signs on arrival to the
ED were stable. You noted that she was maintaining her
airway and had equal breath sounds bilaterally, so you
decided to closely monitor her respiratory status and provide supplemental oxygen but to not intervene further at
that time. Her secondary survey demonstrated abdominal
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