Creation of Adam by Michelangelo:

If we look at the creation of Adam its a good example of simulacrum because there
is no proof that there was in fact Adam or that god even created nor is there any
proof of God himself, its just a concept.
Mona Lisa by Leonardo Da Vinci:

The Mona Lisa is another example of simulacra because there is no concrete

evidence that the Mona Lisa actually exists , there are even theories that people
today seem to believe for example there are theories that the Mona Lisa is a
painting that contains hidden codes and theres even a theory that its a painting of
an extraterrestrial.
Resurrection of Christ by Raphael:

No one has any proof, nor historical evidence that Jesus actually rose from the grave
as shown in the painting.
The Last Judgement by Michelangelo:

Theres no evidence that there would not actually be a final judgement nor is there
any proof of the existence of heaven and hell or that Jesus would actually come
back to this earth.