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CHAPTER

Therapeutic
Agents
KEATH L. MARX, DVM

Editors Disclaimer:
Every attempt has been made to ensure accurate citation
of dosages and references. However, the reader must
assume ultimate responsibility for the use of any medication. Indications and usage listed are as per the reference(s) cited, and may not bear pharmacodynamic data
verifying efficacy or safety.
Dosages that vary significantly (by a factor of 50x or
greater) from other empirical or pharmacokinetic studies may be omitted from the table, but may be found in
the references.
No claims to efficacy or safety are intended or implied.
See abbreviations key at the end.

Nebulize

22 mg/ml
52
2-8 g/kg
2-8 g/kg
2-10 g/kg
1 g/L water
400 mg/kg food
80
25
40
80
330
0.4 g/L
10
80
40
1 g/L feed
0.4 g/L water
80
80
333

100
50
100
50

Amazon, Red Lored

Avian

Avian
Psittacine
Raptor

Avian
Avian
Avian
Avian
Avian
Avian
Avian
Avian
Chicken
Macaw
Parakeet, Quaker
Parakeet, Quaker
Psittacine
Psittacine
Raptor (Peregrine falcon)
Raptor

Avian
Avian
Bird, Aquatic
Bird, Aquatic

Acetylcysteine

Activated Charcoal

Activated Charcoal
Activated Charcoal
Activated Charcoal

Acyclovir
Acyclovir
Acyclovir
Acyclovir
Acyclovir
Acyclovir
Acyclovir
Acyclovir
Acyclovir
Acyclovir
Acyclovir
Acyclovir
Acyclovir
Acyclovir
Acyclovir
Acyclovir

Albendazole
Albendazole
Albendazole
Albendazole

Once
QD
Once
QD

NL
Once
TID
NL
TID
TID
BID
QD
QD
TID
TID
QD
NL
TID
TID
BID

NL
PRN
PRN

Once

QD

QD
PRN
PRN
PRN
PRN
PRN
PRN
PRN
PRN

DOSAGE
INTERVAL

E
E
E
E

A
A
E
G
G
G
G
G
B
A
A
A
E
E
G
G

E
E
E

E
G
D
B
D
D
E
G
G

Juvenile dosage

94

1526
1526
1503
1503

For Pacheco's virus

For nematodes and Capillaria


For nematodes and Capillaria
For nematodes and Capillaria
For nematodes and Capillaria

Change feed BID

For Pacheco's disease


For Pacheco's disease

For herpesvirus, (also ref # 1560, 1650)

Absorb ingested toxins


Antidiarrheal, absorbs toxins

Give after first dose of fluids for oiled birds

10% concentration

COMMENTS (see references for


duration, precautions and
contraindications)
Add ketamine
Add etorphine
Add ketamine
Add etorphine
Add etorphine + xylazine
Add ketamine
Add ketamine

435
435
1470, 1473
435
1306
1306
1352
1352
435
435
1060
1060
763
1365

1554, 1745
1240
1400

1526

700

53, 704
447
1401
447
1401
1401
1386
418
418

C.I.** REFERENCE

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

PO
PO
PO
PO

Drink
Feed
PO
IM
IM
PO
Gavage
Drink
IM
PO
IM
Feed
Drink
PO
PO
PO

PO
PO
PO

PO

IM
IM
NL
IM
NL
NL
IM
IM
IV

Avian
Cassowary, Double-wattled
Hawk
Ostrich
Ostrich
Owl
Raptor
Ratite
Ratite

Acepromazine Maleate
Acepromazine Maleate
Acepromazine Maleate
Acepromazine Maleate
Acepromazine Maleate
Acepromazine Maleate
Acepromazine Maleate
Acepromazine Maleate
Acepromazine Maleate

ROUTE

DOSAGE (mg/kg
unless otherwise
stated)
0.5-1
0.63
2.0
0.16-0.19
25 MG TD
2.0
2.2
0.25-0.5
0.1-0.2

SPECIES

DRUG NAME

242
C l i n i c a l Av i a n M e d i c i n e - Vo l u m e I

4-8
10
6-12
5.4
5-7
5-10
10

10-15
0.33 g/L
0.67 g/L
10
0.33 g/L
10-30
16 ml/L
30 ml/L
0.001 g/L
25
2
10

Avian
Avian
Buzzard (Augur, Lizzard)
Chicken
Crane

Eagle (African Fish, Hawk, Tawny)


and Falcons
Flamingo
Goshawk, African
Owl, Great-horned
Pelican
Pigeon
Psittacine
Raptor

Avian
Budgerigar
Budgerigar
Psittacine
Psittacine
Psittacine

Avian
Avian

Avian
Avian
Poultry
Turkey

Alfaxalone + Alfadolone
Alfaxalone + Alfadolone
Alfaxalone + Alfadolone
Alfaxalone + Alfadolone
Alfaxalone + Alfadolone

Alfaxalone + Alfadolone

Allopurinol
Allopurinol
Allopurinol
Allopurinol
Allopurinol
Allopurinol

Aloe Vera
Aloe Vera

Amantadine HCl
Amantadine HCl
Amantadine HCl
Amantadine HCl

10

Drink
PO
PO
PO

Drink
Drink

IM, PO
Drink
Drink
PO
Drink
PO

IV
IV
IV
IV
IM-IV
IM-IV
IV

IV

IV
IM-IP
IV
IV
IV

IM-IV-SC

PO
NL
PO
PO
PO

ROUTE

NL
NL
NL
QD

QD
QD

QD
NL
NL
QD
NL
BID

PRN
PRN
PRN
PRN
PRN
PRN
PRN

PRN

PRN
PRN
PRN
PRN
PRN

PRN

QW
NL
QD
Once
BID

DOSAGE
INTERVAL

E
E
G
G

G
G

G
G
E
B
E
E

E
B
B
G
G
E
B

E
E
B
B
E

E
G
E
E
E

1650
1650
435
435

1682
111

58, 704
111
763
1035
1240
1756

1240
1610
1174
595
232
1240
1568

1610

1181
1181
1610
1610
1240

704

1361
1471
1478
1478
1240

C.I.** REFERENCE

For orthomyxoviruses
For orthomyxoviruses

For gout
For hyperuricemia
To treat gout

For wild injured raptors anesthesia induction

May cause transient apnea, surgical anesthesia


for 8 to 10 min

Short duration, may be apnea


Short duration

For trematodes
For fascioliasis
For nematodes and flukes
For nematodes and flukes
Repeat in 2 weeks, antiprotozoal

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

Alfaxalone + Alfadolone
Alfaxalone + Alfadolone
Alfaxalone + Alfadolone
Alfaxalone + Alfadolone
Alfaxalone + Alfadolone
Alfaxalone + Alfadolone
Alfaxalone + Alfadolone

10-36

Avian

Alfaxalone + Alfadolone
5-10
36
10
10
4-8

20
10
50
100
0.264

Crane
Emu
Penguin
Penguin
Ratite

Albendazole
Albendazole
Albendazole
Albendazole
Albendazole

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

Chapter 9 | T H E R A P E U T I C A G E N T S

243

10-15
13-20
10-15
18-20
20
15-20
15-20
10
10-20
15
7.6
10-20
15
15-20
15-40
15-20
7.6-11
10
0.25-0.75
20-40
0.05

0.5
10
6.75
5 ml/L
1-5
10 ml/L

2
3.6 g/L feed

Amazon, Blue-fronted
Amazon, Orange-winged
Avian
Bird, Aquatic
Chicken
Cockatiel
Cockatoo, Goffin
Crane
Fowl, Domestic
Gull
Ostrich
Parrot, Grey
Penguin, African
Pigeon
Psittacine
Raptor
Ratite
Stork, Saddle-billed

Raptor

Raptor

Avian

Avian
Avian

Avian

Pigeon

Psittacine

Avian

Anseriformes
Duck, Mallard

Amikacin Sulfate
Amikacin Sulfate
Amikacin Sulfate
Amikacin Sulfate
Amikacin Sulfate
Amikacin Sulfate
Amikacin Sulfate
Amikacin Sulfate
Amikacin Sulfate
Amikacin Sulfate
Amikacin Sulfate
Amikacin Sulfate
Amikacin Sulfate
Amikacin Sulfate
Amikacin Sulfate
Amikacin Sulfate
Amikacin Sulfate
Amikacin Sulfate

Aminoloid

Aminonitrothiazole

Aminopentamide Sulfate

Aminophylline
Aminophylline

Aminopromazine

Aminothiazole

Amitriptyline HCl

Ammonia Solution

Amobarbital Sodium
Amobarbital Sodium

PO
Feed

Topical

PO

Drink

IM

Nebulize
IV-PO

IM-SC

PO

IM

IM
IM/IV
IM-IV-SC
IM
IM
IM
IM
IM-SC
IM
IM
IM
IM
IM
IM-IV
IM
IM
IM
IM

ROUTE

PRN
Once

PRN

B-QID

QD

NL

BID-TID
q3h

BID

NL

q2w

BID-TID
BID
BID-TID
BID
TID
BID-TID
BID-TID
BID
QD-TID
BID
TID
BID-TID
BID
BID
QD-BID
QD
BID
BID

DOSAGE
INTERVAL

G
G

G
E

A
A
A
E
A
A
A
E
A
E
A
A
G
G
E
G
G
G

4
1398

111

1446, 111, 1240

1240

1209

1199
1151

111, 1240. 1473

1463

111

697
736
1473, 111
1478, 1559
1058
32, 697, 879
697
629
1631
1357
747
112, 692
1353
590
565
1314
1308
1645

C.I.** REFERENCE

Soak food in solution

Add aloe vera + 4 drops sulfonate detergent,


control skin pruritis

For behavioral feather picking

Add acetylcysteine, antibiotic, 5 ml NaCl

Control vomition

For trichomoniasis

Induce molting

Monitor hydration

For salmonellosis

For hens

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

244
C l i n i c a l Av i a n M e d i c i n e - Vo l u m e I

150-175
250
0.2-0.4 g/L
167
150
100
150-175
100-150
100-150
100
0.3 g/L
0.5 g/kg feed
16
25-50
20
100
0.17 g/L
10
100
200
20-90
100
50
18-91
1.5 g/L
150
0.2 g/L
75-100
20
25-50
15-20
55-110
150-175
250
100
150
50
15-22

Avian
Avian
Avian
Avian
Avian
Avian
Avian
Avian
Avian
Bustard
Canary
Canary
Chicken
Currawong, Pied
Duck
Falcon
Galliformes
Goshawk
Gull
Penguin, African
Pigeon
Pigeon
Pigeon
Pigeon
Pigeon
Pigeon
Pigeon
Pigeon
Pigeon
Pigeon
Poultry
Poultry
Psittacine
Psittacine
Psittacine
Raptor
Raptor
Ratite

Amoxicillin
Amoxicillin
Amoxicillin
Amoxicillin
Amoxicillin
Amoxicillin
Amoxicillin
Amoxicillin
Amoxicillin
Amoxicillin
Amoxicillin
Amoxicillin
Amoxicillin
Amoxicillin
Amoxicillin
Amoxicillin
Amoxicillin
Amoxicillin
Amoxicillin
Amoxicillin
Amoxicillin
Amoxicillin
Amoxicillin
Amoxicillin
Amoxicillin
Amoxicillin
Amoxicillin
Amoxicillin
Amoxicillin
Amoxicillin
Amoxicillin
Amoxicillin
Amoxicillin
Amoxicillin
Amoxicillin
Amoxicillin
Amoxicillin
Amoxicillin

PO
IM
Drink
PO
IM-PO
PO
PO
SC
IM
IM-SC
Drink
Feed
PO
PO
Drink
Parenteral
Drink
PO
PO
PO
PO
PO
IM
PO
Drink
IV-PO
Drink
PO
Drink
PO
Drink
PO
PO
IM
SC
IM-PO
IM
PO

ROUTE

QD-BID
QD
QD
QD-BID
NL
BID
QD-BID
QD
NL
BID
NL
Once
QD
BID
QD
q2d
QD
BID
QD-BID
TID
QD-BID
QD-BID
QD-BID
QD-BID
NL
NL
NL
BID
QD
QD
QD
BID-TID
QD-BID
QD
NL
BID
BID
BID

DOSAGE
INTERVAL

E
E
E
E
E
E
E
E
G
E
A
A
B
G
C
G
E
G
E
G
A
A
A
A
A
A
A
A
C
G
C
G
E
E
G
E
E
G

111
704
704
741
924
1431
1473
1526
1618
1240
1139
1139
1006
1609
705
1128
704
127
1357
1353
493
565
565
733
800
800
993
1066
704
47
705
585
565
1140
1613
1400
1612
1308

C.I.** REFERENCE

Bacterial infections

Use capsules
Gram negative bacteria
Gram positive bacteria
Use high dosage for Enterobacteriaceae
For Streptococcus bovi s
For Streptococcus bovis

Precede with ticarcillin

Post-surgical

Broad spectrum
For open fractures

Broad spectrum

Long-lasting preparation
Soft feed

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

Chapter 9 | T H E R A P E U T I C A G E N T S

245

10 g/L
3000
10 g/L
3000
100-250
150
150-200
125
125
100
50
150-175
125-150
125
0.5 g/L
50
125
200
125
100
150
125

Avian

Avian
Avian
Avian

Bustard
Pigeon
Pigeon

Amazon Parrot

Avian

Avian

Avian

Avian

Bird, Aquatic

Canary

Chicken

Hawk, Red-tailed

Owl, Great-horned

Passerine

Pigeon

Psittacine

Raptor

Raptor

Amoxicillin + Tylosin

Amoxicillin + Tylosin
Amoxicillin + Tylosin
Amoxicillin + Tylosin

Amoxicillin Depot
Amoxicillin Depot
Amoxicillin Depot

Amoxicillin Sodium +
Clavulanate Potassium
Amoxicillin Sodium +
Clavulanate Potassium
Amoxicillin Sodium +
Clavulanate Potassium
Amoxicillin Sodium +
Clavulanate Potassium
Amoxicillin Sodium +
Clavulanate Potassium
Amoxicillin Sodium +
Clavulanate Potassium
Amoxicillin Sodium +
Clavulanate Potassium
Amoxicillin Sodium +
Clavulanate Potassium
Amoxicillin Sodium +
Clavulanate Potassium
Amoxicillin Sodium +
Clavulanate Potassium
Amoxicillin Sodium +
Clavulanate Potassium
Amoxicillin Sodium +
Clavulanate Potassium
Amoxicillin Sodium +
Clavulanate Potassium
Amoxicillin Sodium +
Clavulanate Potassium
Amoxicillin Sodium +
Clavulanate Potassium
PO

PO, IM

PO

Gavage

NL

PO

PO

Drink

Gavage

IM, PO

IM-PO

IM

PO, IM

PO

NL

IM-SC
IM
SC

PO
Drink
PO

Drink

ROUTE

BID

BID

BID

BID

TID

BID

BID

NL

BID

BID

BID

BID-QID

BID

QID

TID

q3-7d
q2d
QD

QD
QD
QD

QD

DOSAGE
INTERVAL

A
A
A

E
E
E

234

1400, 1433

1446

751

1489

173

1626

801

1139

1478

1474

1470

1431

704

1491

1127, 1240
493
991

1492
1650
1650

1492

C.I.** REFERENCE

Can be nephrotoxic

For staphylococcal dermatitis

For localized gut infection

For frostbite associated skin infection

Post-operative

For GI infection

Pre- and post-operative

For neonatal septicemia

For bacterial infection with liver disease

Useful in young birds

Dosage based on amoxicillin

Long-lasting formulation
Long-lasting oil based susp.

For flock treatment of bacterial and


mycoplasmal infections

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

246
C l i n i c a l Av i a n M e d i c i n e - Vo l u m e I

50-75 mg TD
1

0.33-0.67 g/L
1
1.5
1.5
1
1.5

150-200

Amazon, Yellow-naped
Avian

Avian
Avian

Avian

Avian
Bird, Aquatic
Bird, Aquatic
Budgerigar

Crane
Gull
Gull
Psittacine
Psittacine
Raptor

Amazon Parrot

Anseriformes
Avian
Avian
Canary
Canary
Crane
Crane, Greater Sand Hill
Emu
Falcon
Parrot, Blue-naped

Pigeon
Pigeon

Amphotericin B
Amphotericin B

Amphotericin B
Amphotericin B

Amphotericin B

Amphotericin B
Amphotericin B
Amphotericin B
Amphotericin B

Amphotericin B
Amphotericin B
Amphotericin B
Amphotericin B
Amphotericin B
Amphotericin B

Ampicillin

Ampicillin
Ampicillin
Ampicillin
Ampicillin
Ampicillin
Ampicillin
Ampicillin
Ampicillin
Ampicillin
Ampicillin

Ampicillin
Ampicillin

PO
IM

IM
Feed
Drink
Drink
Feed
IM-SC
IM
IM
IM-PO
PO

PO

Nebulize
IT
IV
IV
IT
IV

IP
PO
IV-SC
PO

Nebulize

IV
PO

IT
IT

IV-PO

ROUTE

QD-BID
q2d

q4h
QD
QD
QD
QD
BID
BID
BID
BID
BID-TID

BID-TID

TID
BID
TID
BID-TID
BID-TID
TID

QD
TID-QID
QD
BID

BID

TID
BID

QD
TID

TID

DOSAGE
INTERVAL

A
A

E
E
E
G
G
A
A
A
E
A

G
E
E
E
E
B

G
E
E
B

E
E

G
E

493
493

1318, 1358
741
741
49
49
596
847
847
1027
567

567

1361
1357
1357
111, 745
111, 741, 1309
1178

861
1503
1503
589

1526

625, 674
1492

740
625

1308

C.I.** REFERENCE

May give combination of both oral and


parenteral
Use capsules
Long-lasting formulation

In soft food

May give combination of both oral and


parenteral

Add IT amphotericin B + flucytosine +


rifampin for aspergillosis

For GI candidiasis
For aspergillosis therapy
For macrorhabdosis (formerly megabacteria
or avian gastric yeast)

Add flucytosine + IV amphotericin B,


aspergillosis therapy
See above
For macrorhabdosis (formerly megabacteria
or avian gastric yeast)
For aspergillosis therapy. Must use sterile
water - NaCl inactivates Amphotericin

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

25-120
100

100
0.25g/kg
1.041 g/L
1-2 g/L
2-3 g/kg food
15-20
20
20
100
150-200

1
100-200
1.5
109

0.83gL

1.5
100

11-15

Ratite

Amoxicillin Sodium +
Clavulanate Potassium

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

Chapter 9 | T H E R A P E U T I C A G E N T S

247

150
773
155
0.1 - 0.2 g/L
0.048-0.096g/L
0.08 g/L
40-250 mg/kg food
0.06 g/L
0.2 g/L
1.25 cc/L
0.25 g/L

0.5 g/L

Pigeon
Pigeon
Pigeon
Ratite

Avian
Avian

Chicken
Crane
Pigeon
Poultry
Psittacine

Chicken

Ampicillin Sodium
Ampicillin Sodium
Ampicillin Sodium
Ampicillin Sodium

Amprolium
Amprolium

Amprolium
Amprolium
Amprolium
Amprolium
Amprolium

Apramycin

20-40
20-50
20-40
20-50 mg TD
250

0.4 KIU/kg
1.7 KIU/kg

Avian

Avian
Avian
Ostrich
Raptor

Avian
Owl, Great-horned

Ascorbic Acid

Ascorbic Acid
Ascorbic Acid
Ascorbic Acid
Ascorbic Acid

Asparaginase
Asparaginase

IM
SC

IM-PO
IM
IM
PO

IM

Feed

PO

Drink

Feed
Drink
Drink
Drink
Drink

Drink
Drink

IM
IM
IM
Drink

IM

Parenteral
IM
PO
IM

ROUTE

QW
Once

NL
QD-QW
q2d
QD

QD-QW

QD

QH

QD

QD
QD
QD
QD
QD

QD
QD

QD-BID
QD-BID
QD-BID
NL

q4-8h

BID-TID
q4h
QID
NL

DOSAGE
INTERVAL

E
F

E
E
G
E

E
E
G
G
E

E
E

A
A
A
G

G
E
E
E

1470
125

924
1473
401
1359

1473

564

1089

881

564
1361
232
585
1365

111
1492

493
733
733
418

567

585
111
1240
1463

C.I.** REFERENCE

For chicks
Antioxidant therapy, administer during lead
chelation therapy

For viral infection, liver disease, stress

Nutritional use, 5-day slaughter withdrawal

Give thiabendazole previous day

For colibacillosis

Use 20% powder formulation


For sarcocystosis

Coccidiostatic, overdose reversed by


administration of vitamin B complex
No slaughter withdrawal
For coccidiosis

Clostridial treatment

For Enterobacteriaceae

May give combination of both oral and


parenteral

Poorly absorbed

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

0.1 g/kg food

Poultry

Arsanilic Acid

1-1.6

50-100

Amazon Parrot

Ampicillin Sodium

Arecoline Hydrobromide Pelican, Brown

55-110
100
100-200
100-250

Poultry
Psittacine
Psittacine
Raptor

Ampicillin
Ampicillin
Ampicillin
Ampicillin

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

248
C l i n i c a l Av i a n M e d i c i n e - Vo l u m e I

0.5-1

0.5-1
5
1.2 g/L
5
0.5-1
1
10 drops/kg
33-66 drops/kg

0.25 mg TD
0.5
0.25-0.38
0.1
0.04-0.1
0.1-0.2
0.2-0.5
0.01-0.02
0.1-0.2
0.2

0.1
0.02-0.05
5-20 g/L

Amazon, Red Lored

Amazon, Yellow-naped
Avian
Avian
Avian
Psittacine
Stork, Saddle-billed

Avian
Avian

Anseriformes

Avian

Duck, Mallard
Pigeon
Psittacine

Anseriformes
Avian
Avian
Avian
Avian
Avian
Canary

Pigeon
Psittacine
Psittacine
Raptor

Raptor
Raptor

Poultry

Aspirin

Aspirin
Aspirin
Aspirin
Aspirin
Aspirin
Aspirin

Astragalus
Astragalus

Atipamezole
Atipamezole

Atipamezole

Atipamezole
Atipamezole
Atipamezole

Atropine
Atropine
Atropine
Atropine
Atropine
Atropine
Atropine

Atropine
Atropine
Atropine
Atropine

Atropine
Atropine

Azamethiphos

Topical

IM-IV
IM-IV

IM-IV
IM-SC
IM-SC
IM-IV

IM-IV
IM-SC
IM-SC
IV
Parenteral
IM-SC
Parenteral

IV
IM
IM

IM

IV

PO
PO

PO
PO
Drink
PO
PO
PO

PO

ROUTE

NL

q3-4h
PRN

q4-8h
QH
NL
PRN

q3-4h
Once
q4h
q3-4h
q3-4h
PRN
q4h

PRN
PRN
PRN

PRN

PRN

TID
QD

BID
TID-QID
QD
TID
QD-BID
QD

QD-BID

DOSAGE
INTERVAL

E
E

G
E
E
G

D
G
E
E
E
G
G

B
B
E

E
E

G
D
E
G
E
G

1479

1240, 1400
1359

590
1240
1688
61

1150
1309
1151
1554
1650
1309
1714

764
1588
1240

1181

1503

1205
1435

1033
1533
1650
1341, 1671
1756
1645

1756

C.I.** REFERENCE

Apply to animal facilities, insect spray

[May thicken secretions and increase risk of


airway obstruction - KLM]
For acetylcholinesterase poisoning
For organophosphate toxicity

For acetylcholinesterase poisoning

For anticholinesterase poisoning


Preanesthetic
For cholinergic toxin
For anticholinesterase toxicity
For organophosphate toxicity
For organophosphate poisoning
For convulsions possibly caused by
organophosphate toxicity

Add flumazenil to reverse ketamine +


medetomidine + midazolam
Reverse ketamine + xylazine or ketamine +
medetomidine
Add flumazenil
Reverse medetomidine
Reverse xylazine or medetomidine

Chronic GI problems and infections


Immune stimulant

Add fatty acid omega 6:omega 3 < 6:1 ratio,


use until renal histology normalizes for renal
disease

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

0.27
0.05
0.5
0.5

0.25-0.38

0.25

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

Chapter 9 | T H E R A P E U T I C A G E N T S

249

4-6
3.3-6.6
0.5-2

50-80
43
40
1 drop
45-75 drops/L
110-220 mg/kg feed
0.4 g/L
3.3 mg/kg feed
0.07 mg/kg feed
50 ml/kg
10-20 ml/kg

25% solution
10% solution
0.1
0.1
1
0.025
0.05
35
35-88

Ostrich
Ostrich
Ratite

Avian
Avian

Falcon

Avian

Avian

Poultry

Ratite

Chicken
Ostrich

Avian
Avian

Pigeon
Raptor

Avian

Bird, Aquatic
Pigeon

Raptor
Raptor

Avian
Avian

Azaperone
Azaperone
Azaperone

Azithromycin
Azithromycin

Azithromycin

Bach flower

Bach flower

Bacitracin

Bacitracin

Bambermycin
Bambermycin

Barium Sulfate
Barium Sulfate

Benzyl Benzoate
Benzyl Benzoate

Betamethasone

Betamethasone
Betamethasone

Biotin
Biotin

Bismuth Subsalicylate
Bismuth Subsalicylate

PO
PO

PO
PO

IM
IM

IM

Topical
Topical

PO
PO

Feed
Feed

Drink

Feed

PO

Drink

PO

PO
PO

IM
IM
IM

ROUTE

BID
Once

QD
QD

NL
Once

NL

PRN
QD

NL
NL

Once
Once

NL

QD

QID

QID

QW

QD
QD

PRN
PRN
Once

DOSAGE
INTERVAL

E
E

E
E

D, E,
G
E
E

E
E

E
E

B
C

G
G

B
G
G

1240
1526

1068
1240

1503
704

201, 1533, 1573

704
1612

1151
1482

400
283

418

564

912

912

1157

702
1154

522
283
1226

C.I.** REFERENCE

May help remove ingested toxins


Enteric coating for oiled birds

During regrowth of claw


Aid in beak and claw growth

Anaphylaxis

Apply to lesion
For Knemidocoptes

G.I. protectant and antiinflammatory


Mix 50:50 with hand-feeding formula for GI
contrast rads

Growth promotant

Clostridial therapy

Nutritional use, no slaughter withdrawal

For calming effect, also apply topically as


spray
See above

For chlamydophilosis
Add ethambutol + rifabutin for
mycobacteriosis
For chlamydophilosis

Add metomidate, chick dosage


Add metomidate
Add ketamine + diazepam after 10 to 15
minutes, sedation

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

250
C l i n i c a l Av i a n M e d i c i n e - Vo l u m e I

25
2

0.01-0.05
0.5
1-3
1
1-2
1
4
3-4
3-4
2-4
0.7
2
0.000025 (0.025ug/kg) Gavage

200

Raptor

Parrot, Grey

Avian
Pigeon

Amazon, Hispaniolan
Cockatoo
Parrot, Grey

Parrot, Grey
Pigeon
Psittacine
Psittacine
Raptor
Rhea
Toucan, Toco

Avian

Avian

Avian

Goshawk
Pigeon

Psittacine
Raptor

Bunamidine HCl

Bupivacaine HCl

Buprenorphine HCl
Buprenorphine HCl

Butorphanol Tartrate
Butorphanol Tartrate
Butorphanol Tartrate

Butorphanol Tartrate
Butorphanol Tartrate
Butorphanol Tartrate
Butorphanol Tartrate
Butorphanol Tartrate
Butorphanol Tartrate
Butorphanol Tartrate

Calcitriol

Calcium Borogluconate

Calcium Borogluconate

Calcium Borogluconate
Calcium Borogluconate

Calcium Borogluconate
Calcium Borogluconate

IM-IV
IV-SC

IV
IM-SC

IM-SC

IM-IV

IM
IM
IV-PO
IV-PO
IM-SC
IM
IM

IM
NL
IM

IM-IV-SC
IM

IM

PO

IM
IM
IM

NL
Once

NL
NL

NL

QD

QD

NL
q3h
NL
TID
QD
PRN
Once

NL
PRN
NL

BID
q5h

PRN

NL

NL
QD-BID
QD

QD

DOSAGE
INTERVAL

E
E

G
E

B
B
E
E
E
G
G

A
B
A

E
B

E
E
E

1240
1240

234
1432

1434

1431

1183

586, 1339
1656
111, 1249
1240
1359
1628
1379

1339
1678
1339

1167
1656

1339

1463

704, 1434
1526, 1617
1612

1358

C.I.** REFERENCE

For egg binding and hypocalcemic tetany

Used during egg laying problems, often with


oxytocin
For egg binding and hypocalcemic tetany

Add calcium source to gavage for


hypocalcaemia

Add ketamine + medetomidine


Post-surgical pain

Also analgesic

Isoflurane sparing
Plasma levels maintained less than 2 hours at
2 mg/kg

Maintain plasma concentration for less than 2


hours

Anthelmintic

Liquefy respiratory mucus


Mucolytic

For niacin deficiency with leg deformities,


weakness, poor growth

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

100-200
100-500

300
100-500

100-500

3-6
1.5
1.5

Avian
Avian
Raptor

Bromhexine HCl
Bromhexine HCl
Bromhexine HCl

Feed

75 g/kg feed

Anseriformes

Brewers yeast

ROUTE

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

Chapter 9 | T H E R A P E U T I C A G E N T S

251

0.44 g/L
150
363

100-300

Avian
Avian

Avian

Avian

Avian
Avian
Avian
Avian

Avian

Calcium Glubionate
Calcium Glubionate

Calcium Glubionate +
Calcium Lactobionate

Calcium Gluconate

Calcium Gluconate
Calcium Gluconate
Calcium Gluconate
Calcium Gluconate

Calcium Gluconate

270
N/A

Avian

Avian

Caprylic Acid

Carbaryl

Topical

PO

PO
PO

IM-SC

NL

NL

QD
QD

BID

NL

QW

NL

NL

BID
NL
NL
NL

NL

QD

NL
BID

Once

Once

DOSAGE
INTERVAL

G
E

E
E
E
E

E
G

111

111

57
1051

88

1621

54

1570

1481

1473
1473
1474
1474

1480

1617

1492
54

1612

1400

C.I.** REFERENCE

5% mixture, powder formulation

Adjunct to aspergillosis therapy

Avoid during breeding season


For ascarids and capillaria

Acute therapy

Add oxytocin for egg binding

For egg binding

Give slowly, follow with oxytocin or


dinoprostone for egg binding, may add
vitamin E + selenium

Slowly to effect

Add phytonadione for bleeding syndrome

For egg binding and calcium deficiencies

For osteodystrophy

For egg binding or hypocalcaemia, give IV


slowly

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

60-100
75

Avian
Pigeon

Cambendazole
Cambendazole

5-10

Calcium Glycerophosphate Parrot, Grey


+ Calcium Lactate

IM

IM

0.5-1

IM-SC

SC

IM-SC
IV
IM
IV

IM-SC

PO

Drink
PO

Feed

IV-SC

ROUTE

5-10

100-300

Calcium Glycerophosphate Lory, Red


+ Calcium Lactate

Calcium
Avian
Glycerophosphate +
Calcium Lactate
Calcium Glycerophosphate Avian
+ Calcium Lactate

10 g/kg food

Raptor

Calcium Carbonate

5-10
50-100
5-10
50-100

10-50

Raptor

Calcium Borogluconate

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

252
C l i n i c a l Av i a n M e d i c i n e - Vo l u m e I

IV
IV

100-200
N/A
125 mg/m3
5
0.1% solution

3 mg TD
0.024
33

Raptor

Avian

Amazon, Yellow-naped
Budgerigar

Avian

Ostrich
Ostrich

Avian

Avian
Bird, Aquatic
Bustard
Dove
Falcon

Finch
Pigeon
Pigeon

Carbenicillin Disodium

Carbon Dioxide Gas

Carboplatin
Carboplatin

Carboxymethylcellulose
Sodium

Carfentanil Citrate
Carfentanil Citrate

Carnidazole

Carnidazole
Carnidazole
Carnidazole
Carnidazole
Carnidazole

Carnidazole
Carnidazole
Carnidazole

PO
PO
PO

PO
PO
PO
PO
PO

PO

IM
NL

Drink

IM

IM-PO
IM
IM
IM-IV
PO
IM
IM
IM
IM
IT

Once
Once
Once

Once
Once
Once
NL
Once

Once

PRN
PRN

QD

q2-3w
QM

NL

TID

NL
TID
BID
BID-TID
BID
BID-TID
TID-QID
BID
TID
QD

NL

DOSAGE
INTERVAL

E
D
E

E
E
E
G
B

B
G

G
G

E
G
G
E
G
G
E
E
E
E

1572
1221
111, 1473

1554
1503
1240
61
1420

1526

521
465

1457

1033
1259

1564

1400

924
55
861
629, 1361
173
260
565
763
1240
1240

1240

C.I.** REFERENCE

For trichomoniasis

For Ttichomoniasis, less effective than


multiday dimetridazole

For trichomoniasis, no food/water night


before treatment plus no water 2 to 3 hours
after treatment
For trichomoniasis and giardiasis

Add xylazine

Add amphotericin B, mix fresh daily, allow to


stand overnight, dissolve drug in the AM

Dilute with 5% dextrose


Dilute 1:10 with sterile water

Euthanasia

For Gram negative bacteria, synergistic


w/aminoglycosides

Freeze small portions indefinitely

Gram negative, Pseudomonas

5% mixture, lightly dust feathers for


ectoparasites

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

20-30
20-30
200

20-30
33
20-25
30
25

IH

150
100
100-200
100
150
100
100-200
100
100-200
100

Avian
Avian
Avian
Crane
Owl, Great-horned
Pigeon
Psittacine
Psittacine
Raptor
Raptor

Carbenicillin Disodium
Carbenicillin Disodium
Carbenicillin Disodium
Carbenicillin Disodium
Carbenicillin Disodium
Carbenicillin Disodium
Carbenicillin Disodium
Carbenicillin Disodium
Carbenicillin Disodium
Carbenicillin Disodium

Topical

N/A

Avian

ROUTE

Carbaryl

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

Chapter 9 | T H E R A P E U T I C A G E N T S

253

30
4
4
5-10
1-2
4
5-10
1-2
5-10
2-10
1-2
2-10
100
25-30
11-55
100
75-100
100
75-100
100
50-100
100
100
50-100
50-100
100

Raptor

Amazon, Orange-winged
Anseriformes
Anseriformes
Avian
Avian
Avian
Bird, Aquatic
Pigeon
Psittacine
Raptor
Raptor

Pigeon

Crane
Poultry
Raptor

Amazon Parrot
Amazon, Blue-fronted
Avian
Bird, Aquatic
Crane
Hawk, Red-tailed
Pigeon
Psittacine
Psittacine
Psittacine

Raptor

Ratite

Carnidazole

Carprofen
Carprofen
Carprofen
Carprofen
Carprofen
Carprofen
Carprofen
Carprofen
Carprofen
Carprofen
Carprofen

Cefadroxil

Cefazolin Sodium
Cefazolin Sodium
Cefazolin Sodium

Cefotaxime Sodium
Cefotaxime Sodium
Cefotaxime Sodium
Cefotaxime Sodium
Cefotaxime Sodium
Cefotaxime Sodium
Cefotaxime Sodium
Cefotaxime Sodium
Cefotaxime Sodium
Cefotaxime Sodium

Cefotaxime Sodium

Cefotaxime Sodium

IM

IM-IV

IM
IM
IM-IV
IM
IM-SC
IM
IM
IM
SC
IM

IM-IV
NL
IM

PO

IM
SC
IM
IM-PO
IM-IV-PO
IM
IM-PO
IM
IM-IV-SC
IM-IV-PO
IM-IV-SC

PO

PO
PO
PO

ROUTE

TID

Once

q4-8h
TID
TID-QID
TID-QID
TID
NL
BID-TID
TID
TID
BID

TID
BID-TID
Once

BID

BID
QD
NL
BID
NL
QD
BID
NL
QD
BID
QD

QD

Once
QW-q2w
Once

DOSAGE
INTERVAL

A
A
A
E
E
G
G
E
E
E

E
G
E

G
E
G
D
E
E
E
G
E
D
E

E
E
E

1308

1359

697
748
1473
1478
629
1626
260
565
632
763

629
585
1359

260

1377
1190
1345
1533
1167
1431
1503
1345
1240
1400
1240

61

1240
1364
1240

C.I.** REFERENCE

Neonate dosage
Frozen reconstituted drugs lasts 12 weeks in
freezer, 10 days in refrigerator
Perioperative, use amoxicillin/clavulanate
post-operative
For young birds

Intra-operative

For hock joint pressure sore infections

Perioperative, use amoxicillin/clavulanate


post-operative

Post-surgical pain

Post-surgical pain

Pre-operative painkiller

Post-surgical

For trichomoniasis, hexamitiasis,


histomoniasis, use lower dosage for juveniles

Use lower dosage for juveniles

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

25

100

12.5-25
20-30
20-30

Pigeon
Pigeon
Psittacine

Carnidazole
Carnidazole
Carnidazole

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

254
C l i n i c a l Av i a n M e d i c i n e - Vo l u m e I

75-200
10
50-100
0.16 mg TD
10
100
10-20
75-100
75-100
10

35-50
40-100
35-50
35-50
35-50
40-100
35-50
100
100
35-50
35-50
100
35-50
35-50
100
35-50
100
55-110
35-50
100
100
35-50
35-50
40-100
50-100

Psittacine

Amazon, Orange-winged
Avian
Chicken
Cockatiel
Psittacine
Ratite

Amazon Parrot
Avian

Avian (Macaw)

Avian
Avian
Avian
Avian
Bird, Aquatic
Bustard
Crane
Crane
Crane
Crane
Duck
Duck
Duck
Emu
Emu
Pigeon
Pigeon
Poultry
Psittacine
Psittacine
Quail
Quail, Bobwhite
Quail, Japanese
Raptor
Raptor

Ceftazidime

Ceftiofur Sodium
Ceftiofur Sodium
Ceftiofur Sodium
Ceftiofur Sodium
Ceftiofur Sodium
Ceftiofur Sodium

Ceftriaxone Sodium
Ceftriaxone Sodium

Celecoxib

Cephalexin
Cephalexin
Cephalexin
Cephalexin
Cephalexin
Cephalexin
Cephalexin
Cephalexin
Cephalexin
Cephalexin
Cephalexin
Cephalexin
Cephalexin
Cephalexin
Cephalexin
Cephalexin
Cephalexin
Cephalexin
Cephalexin
Cephalexin
Cephalexin
Cephalexin
Cephalexin
Cephalexin
Cephalexin

PO
IM-PO
PO
PO
PO
IM-PO
PO
IM
PO
PO
PO
IM
PO
PO
IM
PO
PO
NL
PO
PO
IM
PO
PO
IM-PO
IM-PO

PO

IM
IM-IV

IM
IM
IM
IM
IM
IM

IM-IV

ROUTE

q4-6h
TID-QID
q4-6h
QID
QID
TID-QID
QID
QID
q4-6h
QID
q2-3h
BID-TID
QID
QID
QID
QID
BID-TID
BID
QID
TID
BID-TID
q2-3h
QID
TID-QID
TID

QD

q4-8h
TID-QID

BID-TID
QID
QD
q4h
TID
BID

BID-QID

DOSAGE
INTERVAL

E
E
E
E
E
E
A
A
E
A
A
A
A
A
A
A
G
G
E
G
A
A
A
E
E

A
E

A
E
A
A
E
G

111
1240
1473
1492
1503
1240
596
697
111
457, 847
457
697
847
418, 457, 847
697
847
260
585
763
697
697
457
847
1240
1400

1750

697
111

788
1240
788
788
1756
1308

1756

C.I.** REFERENCE

For E. coli and Proteus

For E. coli and Proteus

For proventricular dilatation disease


symptoms

For bacterial nephritis

For bacterial nephritis

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

Chapter 9 | T H E R A P E U T I C A G E N T S

255

35-50
100
100
< 50

0.4-0.48g/L bait
2 g/kg grain
0.02-0.025 mg TD
1.54-1.79 g/L corn
0.4-0.5 g/L bait
15
40
8 g/L corn

Avian

Avian (budgerigar, canary, chicken, 106.5


crow, crane)

106.5
106.5
106.5
106.5

Avian
Crane
Emu, pigeon

Eagle, Golden
Falcon, Prairie
Gull (California, Laughing,
Herring)
Hawk (Marsh, Red-tailed,
Swainson's)
Owl, Saw-whet
Pea Fowl, pheasant
Pigeon, sparrow, toucanet
Rail, Wood

Anseriformes
Bird, Seed-eater
Blackbird, Red-winged
Crane
Duck
Duck, Mallard
Duck, Mallard
Turkey

Cephradine
Cephradine
Cephradine

Chitosan

Chloral Hydrate

Chloral Hydrate
Chloral Hydrate
Chloral Hydrate

Chloralose
Chloralose
Chloralose
Chloralose
Chloralose
Chloralose
Chloralose
Chloralose

64-68

Feed
Feed
Feed
Feed
Feed
Feed
PO
Feed

IM
IM
IM
IM

IM

IM
IM
IM

IM

Topical

PO
PO
PO

IM-IV
IM-IV
IM
IM
IM-IV

PO
PO

ROUTE

Once
Once
Once
Once
Once
Once
PRN
Once

PRN
PRN
PRN
PRN

PRN

PRN
PRN
PRN

PRN

q3d-q2w

q4-6h
q4-6h
q4-6h

QID
QID
q2-6h
QID
QID

QID
TID

DOSAGE
INTERVAL

G
E
G
G
G
B
D
E

B
B
B
B

B
B
B

E
E
E

A
E
E
E
G

G
G

1230
4
1230
1361
1386
1095
1401
1386

1084
1084
1084
1084

1086

1086
1086
1084

1084

1633

111, 1473
111
1473

1473
111
565
741
1308

234
1308

C.I.** REFERENCE

Sedation in 40-60 min, 9% mortality

Add diazepam

Add secobarbital

Add diazepam for anesthesia

Add magnesium sulfate + pentobarbital


sodium, reduce dose 15 to 20% in debilitated
birds

Rinse and apply sparingly to wound surface


or pack suppurating wound, promote wound
healing

No gastrointestinal absorption

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

Chloral Hydrate
Chloral Hydrate
Chloral Hydrate
Chloral Hydrate

Chloral Hydrate

100
100
100
100
30-40

Avian
Avian
Avian
Avian
Ratite

Cephalothin Sodium
Cephalothin Sodium
Cephalothin Sodium
Cephalothin Sodium
Cephalothin Sodium

80.9
64
106.5

50
15-22

Raptor
Ratite

Cephalexin
Cephalexin

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

256
C l i n i c a l Av i a n M e d i c i n e - Vo l u m e I

50

Chloramphenicol Palmitate Turkey

Feed

PO

PO

Once

QID

BID-QID

TID-QID

TID

BID

QD
TD
QD
BID
QD
BID
QID
TID
QID
q3h
TID
BID
QD
BID
BID
QID
BID
BID
QD
QID
TID
QID
BID
TID-QID
TID
TID

DOSAGE
INTERVAL

E
E
E
A
E
A
A
A
A
A
A
A
A
A
A
A
G
A
A
E
E
E
E
E
E
G

1094

741

741

739

55

741

704
704
704
394
695
394
394
596
508
508
508
394
394
394
394
394
401
394
394
111
704
1473
1650
111
1240
1308

C.I.** REFERENCE

Anesthesia

For large birds

Not for food animals

Without grit in diet


For salmonellosis

With grit in diet

Double dosage for birds below 5 kg

In soft food

Dilute in 15 ml 0.9% saline solution

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

150 g/kg food

100

Chloramphenicol Palmitate Psittacine

Cowbird, quail

150-200

Chloramphenicol Palmitate Avian

Chlordiazepoxide HCl

PO

50

PO

Gavage

PO
Nebulize
Parenteral
IM
Feed
IM
IM
SC
IM-IV
IM-IV
IM-IV
IM
IM
IM
IM
IM
IM
IM
IM
PO
PO
PO
IM
IM-IV
IM
IM-IV-POSC

80-100

50-100
200 mg
50-100
50
0.1-0.15 g/L
50
50
100
100
25
240
50
50
50
50
50
10
50
50
95
50
30
80
50
50
35-50

Avian
Avian
Avian
Budgerigar
Canary
Chicken
Conure (Nanday, Sun)
Crane
Duck, Chinese
Duck, Chinese
Duck, Chinese
Duck, Muscovy
Eagle
Goose, Egyptian
Hawk
Macaw
Ostrich
Owl, Barred
Pea Fowl
Pigeon
Pigeon
Pigeon
Pigeon
Psittacine
Raptor
Ratite

Chloramphenicol
Chloramphenicol
Chloramphenicol
Chloramphenicol
Chloramphenicol
Chloramphenicol
Chloramphenicol
Chloramphenicol
Chloramphenicol
Chloramphenicol
Chloramphenicol
Chloramphenicol
Chloramphenicol
Chloramphenicol
Chloramphenicol
Chloramphenicol
Chloramphenicol
Chloramphenicol
Chloramphenicol
Chloramphenicol
Chloramphenicol
Chloramphenicol
Chloramphenicol
Chloramphenicol
Chloramphenicol
Chloramphenicol

ROUTE

Chloramphenicol
Avian
Palmitate
Chloramphenicol Palmitate Avian

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

Chapter 9 | T H E R A P E U T I C A G E N T S

257

SPECIES

5
5
5
25
10
0.0125 g/L
2.5 g/kg corn
2.5 - 5.0 g/kg food
5 g/kg food
1 g/L
5 g/L
100
0.5 g/L
100
34
5 g/kg seed
500 mg/kg food
1.5 g/kg food
2.5 g/L
2.5 g/kg food

Avian
Avian

Avian
Avian
Avian
Falcon

Passerine, Small

Penguin
Penguin, African
Raptor
Raptor
Raptor

Avian

Amazon, Blue-fronted
Amazon, Green-cheeked
Amazons
Avian
Avian
Avian
Avian
Avian
Avian
Budgerigar
Budgerigar
Canary
Chicken
Chicken

Chicken
Chicken

Chlorhexidine Gluconate
Chlorhexidine Gluconate

Chloroquine
Chloroquine
Chloroquine
Chloroquine

Chloroquine

Chloroquine
Chloroquine
Chloroquine
Chloroquine
Chloroquine

Chlorpromazine

Chlortetracycline HCl
Chlortetracycline HCl
Chlortetracycline HCl
Chlortetracycline HCl
Chlortetracycline HCl
Chlortetracycline HCl
Chlortetracycline HCl
Chlortetracycline HCl
Chlortetracycline HCl
Chlortetracycline HCl
Chlortetracycline HCl
Chlortetracycline HCl
Chlortetracycline HCl
Chlortetracycline HCl

Chlortetracycline HCl
Chlortetracycline HCl

PO
Feed

Feed
Feed
Feed
Drink
Drink
PO
Drink
IM-PO
IV
Feed
Feed
Feed
Drink
Feed

Drink

PO
PO
NL
IM
PO

Drink

Drink
PO
PO
PO

Flush
Drink

Drink

Drink

ROUTE

NL
QD

QD
Once
QD
QD
QD
QID
QD
NL
NL
QD
QD
QD
NL
Once

NL

QID
QD
NL
QD
QD

NL

QD
TID
QD
Once

NL
QD

NL

NL

DOSAGE
INTERVAL

C
E

A
B
B
E
E
E
E
E
F
A
E
E
A
A

E
B
D
E
G

E
G
G
B

E
E

705
564

230
1062
1079
704
704
704
741
924
1209
731
565
695
802
802

1492, 1650

111, 1240
262
1612
1400
61, 94

1187

1180
57
61
1177

1240
1492

1240

741

C.I.** REFERENCE

No slaughter withdrawal

Add chlortetracycline feed also


Add chlortetracycline drinking water also

Hulled medicated millet


Antichlamydophilial

For chlamydophilosis initial therapy

For therapy less than 2 weeks duration


For Chlamydophila
For Chlamydophila
Prophylactic dosage
Therapeutic dosage

For feather picking and anxiety

Plasmodium and Leucocytozoon


Add primaquine phosphate

Loading dosage 10 mg/kg

For blood parasites


Usually in combination with primaquine
Add primaquine phosphate
Add primaquine, follow 1st dose with 5
mg/kg at hours 6,18 and 24
Therapeutic but not curative for Plasmodium

Wound flush
For candidiasis

Prevent or treat mild intestinal candidiasis

For candidiasis or antimicrobial prophylaxis

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

20-60
220 mg/kg food

2.1 g/L

0.4 g/L
10
10
10

Avian

2.5 ml/L of 2%
solution/L
2.5-7.5 ml of 2%
solution/L
0.5% solution
0.005 g/L

DOSAGE (mg/kg
unless otherwise
stated)

Chlorhexidine Gluconate

Chlorhexidine Gluconate Avian

DRUG NAME

258
C l i n i c a l Av i a n M e d i c i n e - Vo l u m e I

2.5-10 g/kg food


33
15-20
2.5 g/L
10-30
500-1300
10 drops/kg
0.1
35

Cockatoo, G Sulfur-crested
Conure (Maroon-bellied, Nanday)

Finch
Finch
Galliformes
Lorikeet
Lorikeet
Lory (Ornate, purple-naped)
Lovebird, Abyssinian
Macaw, Buffon's
Parakeet (Bourke's, red-front, ringnecked)
Passerine

Passerine

Pigeon
Pigeon
Pigeon
Pigeon
Poultry
Poultry

Psittacine
Raptor
Ratite
Turkey
Turkey

Avian

Avian

Avian

Penguin, African

Chlortetracycline HCl
Chlortetracycline HCl

Chlortetracycline HCl
Chlortetracycline HCl
Chlortetracycline HCl
Chlortetracycline HCl
Chlortetracycline HCl
Chlortetracycline HCl
Chlortetracycline HCl
Chlortetracycline HCl
Chlortetracycline HCl

Chlortetracycline HCl

Chlortetracycline HCl

Chlortetracycline HCl
Chlortetracycline HCl
Chlortetracycline HCl
Chlortetracycline HCl
Chlortetracycline HCl
Chlortetracycline HCl

Chlortetracycline HCl
Chlortetracycline HCl
Chlortetracycline HCl
Chlortetracycline HCl
Chlortetracycline HCl

Choline

Chromium Picolinate

Chromium Picolinate

Cimetidine

PO

PO

PO

Feed

Feed
PO
PO
Drink
PO

PO
IM
PO
Drink
Feed
Feed

Drink

Feed

Drink
Feed
Drink
Feed
Feed
Feed
Feed
Feed
Feed

Feed
Feed

Feed

ROUTE

QD

BID

QD

QD

QD
TID
TID
NL
NL

B-TID
QD
TID-QID
QD
QD
QD

QD

QD

QD
QD
QD
QD
Once
Once
QD
Once
QD

QD
QD

QD

DOSAGE
INTERVAL

A
E
G
A
C

A
G
G
G
C
C

E
E
E
A
A
A
A
A
A

B
A

128

1205

1435

1470

693
1612
1308
802
705

565
232
260
590
564
564

1437

1437

1572
1572
704
1077
1077
1077
738
781
738

1079
738

738

C.I.** REFERENCE

Stock solution 1 pill per 30 ml lactulose for


diabetes

For hepatic lipidosis

Add chlortetracycline feed also

Dosage based on weight of food


For chlamydophilosis

With or without tylosin


Change daily
Prophylactic

Add drug to drink at the same time, use for


30 days for chlamydophilosis
Add drug to food at the same time, use for
30 days for chlamydophilosis
Without grit in diet

Hulled millet + oats for chlamydophilosis

For chlamydophilosis
For chlamydophilosis
For chlamydophilosis

For chlamydophilosis
Hulled millet + oats for chlamydophilosis

Hulled millet + oats for chlamydophilosis

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

40-50
100
50
0.5 g/L
0.106-0.264 g/L
110-550 mg/kg feed

1.0 - 1.5 g/L

1.5 g/kg soft food

1 - 1.5 g/L
1.5 g/kg food
30
0.5 g/kg fruit
0.5 g/L liquid food
0.5g/kg liquid food
2.4 g/kg food
10-15 g/kg
2.4 g/kg food

4.4 g/kg food


2.4 g/kg food

2.4 g/kg food

Cockatiel

Chlortetracycline HCl

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

Chapter 9 | T H E R A P E U T I C A G E N T S

259

PO
NL
PO
Parenteral

10-15
20
5
30
20
50
20
0.25 g/L
5-20
20-40
10
0.5-1
1
0.25
0.3 mg/cm3
0.5 g/L
1.0 g/L
0.2
85

5-10
5-10
6.5
5
5-10
7
5-10
100
150

Avian
Canary
Chicken
Cockatiel
Gull
Hawk, Red-tailed
Ostrich
Pigeon
Pigeon
Psittacine
Toucan, Toco

Avian
Psittacine
Raptor

Macaw, Blue and Gold

Avian
Passerine, Small

Psittacine

Avian

Anseriformes
Pigeon
Pigeon
Pigeon
Poultry
Psittacine
Raptor

Avian
Avian

Ciprofloxacin HCl
Ciprofloxacin HCl
Ciprofloxacin HCl
Ciprofloxacin HCl
Ciprofloxacin HCl
Ciprofloxacin HCl
Ciprofloxacin HCl
Ciprofloxacin HCl
Ciprofloxacin HCl
Ciprofloxacin HCl
Ciprofloxacin HCl

Cisapride
Cisapride
Cisapride

Cisplatin

Citric Acid
Citric Acid

Clanobutin

Clarithromycin

Clazuril
Clazuril
Clazuril
Clazuril
Clazuril
Clazuril
Clazuril

Clindamycin HCl
Clindamycin HCl

PO
PO

PO
PO
PO
PO
PO
PO
PO

PO

PO

Drink
Drink

PO
PO
PO
PO
PO
PO
NL
Drink
PO
PO
PO

PO

QD
QD

q3d
QD
Once
NL
QD
QD
q3d

QD

QD

QD
NL

QW

TID
BID
TID

BID
BID
NL
BID
QD
BID
BID
QD
BID
BID
BID

BID

QD

DOSAGE
INTERVAL

D
E

D
G
G
G
G
E
E

E
E

E
G
E

G
G
A
G
E
A
E
G
G
E
G

1221
1431

1150
57
109
109
57
1240
1240

1154

1722

704
1187

1369

1151
1263
1400

1319
48
797
44
1357
168
628
590
590
111
1379

1571

1470, 1571

C.I.** REFERENCE

For clostridiosis
For osteomyelitis

Repeat after 2 days


Wait 2 days then repeat for coccidiosis
For coccidiosis

For coccidiosis
Repeat after 2 days

Add ethambutol + rifabutin, dose


allometrically for mycobacteriosis

Liver support

Add oxytetracycline

Intralesional-fibrosarcoma

To improve GI motility
For ileus
Increase gut motility

For oviduct infection


Change daily

Add ethambutol + rifampin for liver


mycobacteriosis
Add clofazimine + cycloserine + ethambutol
for avian mycobacteriosis

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

20

Avian

Ciprofloxacin HCl

PO

80

Avian

Ciprofloxacin HCl

ROUTE

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

260
C l i n i c a l Av i a n M e d i c i n e - Vo l u m e I

50
25
30-40
6
1.5
1.5
1-5
0.5-1
3
0.5-1
0.5-1
125-250 mg/kg food
0.25 g/kg food
20
20
20
20
10 g/L
70-100 g/L
100-200
250
100
250

Psittacine
Psittacine
Raptor

Avian

Avian
Psittacine
Raptor

Avian
Cockatoo
Psittacine
Psittacine

Chicken

Poultry

Anseriformes
Avian
Psittacine
Raptor

Crane
Raptor

Avian
Avian
Avian
Raptor

Clindamycin HCl
Clindamycin HCl
Clindamycin HCl

Clofazimine

Clofazimine
Clofazimine
Clofazimine

Clomipramine HCl
Clomipramine HCl
Clomipramine HCl
Clomipramine HCl

Clopidol

Clopidol

Clorsulon
Clorsulon
Clorsulon
Clorsulon

Clotrimazole
Clotrimazole

Cloxacillin Sodium
Cloxacillin Sodium
Cloxacillin Sodium
Cloxacillin Sodium

IM
PO
PO
PO

Nebulize
Nebulize

PO
PO
PO
PO

Feed

Feed

NL
PO
PO
PO

PO
PO
PO

PO

NL
NL
PO

PO
PO
PO
PO
PO
PO
PO
PO

ROUTE

QD
BID
QD
BID

TID
BID

q2w
q2w
q2w
q2w

QD

QD

QD-BID
BID
BID
QD-BID

QD
QD
QD

QD

BID
TID
BID

BID
BID
QD
BID
BID
QD
QD
QD

DOSAGE
INTERVAL

E
E
E
E

E
E

D
G
E
E

D
G
B
E

D
E
E

F
F
B

G
G
E
G
G
A
E
E

565
1234
1470
1240

1361
1359

1150
818
111
1240

564

564

1475
1278
43
111

1571
1240
1240, 1154

1470

1170
1170
1568

1568
1568
1357
1568
173
1473
111
1240

C.I.** REFERENCE

For bumblefoot

Antifungal

For trematodes and cestodes

For cestodes and nematodes


For tapeworms

Prophylactic

5-day slaughter withdrawal, prophylactic

Gradually increase dose over 4 to 5 days

Control of self-mutilation, mixed results


Cloacal prolapse

For mycobacteriosis

Add ethambutol + rifampin for liver


mycobacteriosis

For osteomyelitis and tendon sheath


infections
Used to treat anaerobic osteomyelitis

Add enrofloxacin

For post-operative orthopedic surgery

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

40
40
100-150
40
12.5
100
100
100

Eagle, Little
Goshawk, Brown
Gull
Owl, Barn
Owl, Great-horned
Pigeon
Pigeon
Psittacine

Clindamycin HCl
Clindamycin HCl
Clindamycin HCl
Clindamycin HCl
Clindamycin HCl
Clindamycin HCl
Clindamycin HCl
Clindamycin HCl

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

Chapter 9 | T H E R A P E U T I C A G E N T S

261

0.04
0.01
0.2
0.04
16 IU TD
10%
51% powder
0.5 g/L
1:2000 dilution
0.25-0.5

25
200 mg/m2
5

5
60
10
0.05% solution
2.0% solution
2% solution
0.05 g/L
5

Avian

Avian
Macaw
Psittacine
Psittacine

Avian

Psittacine

Avian
Ostrich

Psittacine

Avian

Owl, Great-horned
Psittacine

Avian

Raptor

Duck, Pekin
Duck, Pekin

Pigeon
Psittacine

Raptor

Chicken
Chicken

Coenzyme Q10

Colchicine
Colchicine
Colchicine
Colchicine

Corticotropin

Crotamiton

Cupric Sulfate
Cupric Sulfate

Cupric Sulfate

Cyanocobalamin

Cyclophosphamide
Cyclophosphamide
Cyclophosphamide

Cycloserine

Cycloserine

Cyclosporine
Cyclosporine

Cypermethrin
Cypermethrin

Cypermethrin

Danofloxacin Mesylate
Danofloxacin Mesylate

Drink
PO

NL

Topical
NL

IV
IV

PO

PO

PO
IO

IM

Topical

Topical
Drink

Topical

IM

PO
PO
PO
PO

PO

IM

ROUTE

NL
QD

NL

QD
NL

QD
TID-QID

BID

BID

Once
QW

QW

q2w

PRN
QD

NL

Once

QD
BID
BID
QD-BID

QD-BID

NL

DOSAGE
INTERVAL

A
B

E
E

A
A

F
E

E
G

D
G
E
E

837
893, 990

1240

704
1240

835
835

1240, 1154

1571

125
1470

111

1446

1240
1254, 283

1240

88, 532

1470
45
111, 1473
1756

1205, 1435

1463

C.I.** REFERENCE

For Mycoplasma gallisepticum


For colisepticemia

Apply as spray
Spray premises for Dermanyssus , avoid contact
with skin

Add ciprofloxacin or enrofloxacin +


clofazimine + ethambutol for avian
mycobacteriosis

**Check current literature prior to use


Maximum dosage listed
Lymphosarcoma

For dermatomycosis

For ulcerative dermatitis


For candidiasis, use acidified copper sulfate

For knemidocoptic mites

For hepatic fibrosis

For heart, geriatric, diabetic, immune


deficient birds

For bacterial infections

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

100-250

Raptor

Cloxacillin Sodium

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

262
C l i n i c a l Av i a n M e d i c i n e - Vo l u m e I

30 mg/kg food
0.03 g/kg food
50

100
20
40
100
1.28 mg/kcal
1
6.67
0.3
0.3
0.3
1-2
2-4
N/A
0.5
2
0.5
0.15-1.5
0.3-3
2-4
4
2-4
0.3-3

1
2

Chicken
Pheasant, Ring-necked

Toucan

Avian

Avian
Mynah
Toucan
Toucan

Avian
Pigeon

Avian
Chicken
Ostrich

Avian
Avian
Avian

Crane, Sarus
Falcon
Heron, Great Blue
Pigeon
Pigeon
Psittacine
Psittacine
Raptor
Raptor

Amazon, Yellow-naped

Anseriformes

Decoquinate
Decoquinate

Deferiprone

Deferoxamine Mesylate

Deferoxamine Mesylate
Deferoxamine Mesylate
Deferoxamine Mesylate
Deferoxamine Mesylate

Delmadinone Acetate
Delmadinone Acetate

Detomidine HCl
Detomidine HCl
Detomidine HCl

Dexamethasone
Dexamethasone
Dexamethasone

Dexamethasone
Dexamethasone
Dexamethasone
Dexamethasone
Dexamethasone
Dexamethasone
Dexamethasone
Dexamethasone
Dexamethasone

Dexamethasone Sodium
Phosphate
Dexamethasone Sodium
Phosphate

IM

IM

IV
IM-IV
IV
IM-IV
IM-IV
IM
IM-SC
IM
IM

IM
IM
Topical

IM
IM
IM

IM
IM

PO
IM
SC
IM

SC

PO

Feed
Feed

ROUTE

QD

q3-7d

Once
Once
Once
BID
BID
QD-BID
NL
QD
q2d

NL
QD
NL

NL
PRN
PRN

NL
NL

Once
QD
QD
QD

QD

BID

QD
QD

DOSAGE
INTERVAL

G
E
G
E
E
E
G
E
E

D
E
E

G
E
E

E
E

G
G
G
E

E
B

1240

1033

1087
1027
1087
1432
1432
1240
632
1433
1240

1533
1431
1151

1320
1573
1573

1434
1432

87
340
1280
1180

1470

1280

564
895

C.I.** REFERENCE

Neonate dosage, shock or sepsis


Use with great care
Long-lasting formulation, reduce
inflammatory response and shock

For shock

For shock, trauma, toxic conditions

Use sparingly
Add dimethyl sulfoxide for cloacal or uterine
prolapse

Sedation
Sedation

Continue IM q4h as needed


Repeat qow for series of 10 treatments
For iron storage disease
Iron chelation

To reduce liver iron levels

For iron storage disease, zinc


supplementation may be required

No slaughter withdrawal, prophylactic


For coccidiosis

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

Chapter 9 | T H E R A P E U T I C A G E N T S

263

2-4
2

N/A
50

500-1000
0.2 ml TD

Psittacine

Raptor

Avian
Avian

Avian
Avian
Avian
Avian

Psittacine

Raptor

Budgerigar

Dextrose
Dextrose

Dextrose
Dextrose
Dextrose
Dextrose

Dextrose

Dextrose

Diatrizoate Meglumine

Crane
Crane
Duck
Emu
Emu
Falcon
Hawk, Rough-legged

Diazepam
Diazepam
Diazepam
Diazepam
Diazepam
Diazepam
Diazepam

0.5-1
0.2-0.5
1.3-1.7 g/kg bait
0.6
5
1.2
1-1.5

1
1.2-1.6 g/L bait
0.5-1
0.5-1
0.6
0.5-1

400

2 ml/kg

NL
NL
Feed
IV
IV
IV
IV

NL
Feed
IM-IV
IM
IM-IV
IM-IV

IV

IP

IV

IV

IV
IV-PO-SC
IV
IV

Topical
IV-PO-SC

IM

IM-IV

IM

IM-IV

ROUTE

PRN
PRN
Once
PRN
NL
PRN
PRN

PRN
Once
BID-TID
NL
PRN
PRN

Once

NL

Once

NL

NL
NL
NL
NL

PRN
NL

QD

NL

QD

Once

DOSAGE
INTERVAL

E
E
G
G
E
D
G

D
G
E
E
E
E

E
E
E
G

E
E

1189
1189
1386
283
4
1401
1092

1403
1230
1240
1120, 1492
1503
1559

1756

95

1400

632

111
1240
1473
1311

1151
1240

1240

1688

1240

1151

C.I.** REFERENCE

For tranquilization 4 to 6 hours


Add ketamine for anesthesia
Add chloralose
Add pentobarbital after 1 hour
Sedation
Add ketamine
Combine with ketamine

For lead poisoning to control convulsions

Add ketamine
Add chloralose
Control seizures
For seizures related to lead toxicoses

For IV excretory urography

Goiter therapy

Give slowly
For hypoglycemia, 50% solution, may be
deleted
Neonate dosage, use 50% solution, slow
bolus
Give slowly for hypoglycemia

For flushing wounds


Isotonic for hypoglycemia and dehydration,
IV slowly
Give slowly

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

Anseriformes
Anseriformes
Anseriformes
Avian
Bird, Aquatic
Bird, Aquatic

Diazepam
Diazepam
Diazepam
Diazepam
Diazepam
Diazepam

Diatrizoate Meglumine + Amazon, Double Yellow-head


Diatrizoate Sodium

Bustard

50-100
50
50-100
1

Avian

Dexamethasone Sodium
Phosphate
Dexamethasone Sodium
Phosphate
Dexamethasone Sodium
Phosphate
Dexamethasone Sodium
Phosphate

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

264
C l i n i c a l Av i a n M e d i c i n e - Vo l u m e I

5
1.3-1.7 g/kg bait
200 mg/kg food
374 mg/kg food
100 mg/TD
N/A
N/A
0.5-1.0 mg/kg food
10

Owl
Passerine

Pigeon

Pigeon
Psittacine
Psittacine
Psittacine
Raptor
Raptor
Ratite
Ratite
Ratite
Ratite

Rhea
Swan

Chicken
Poultry

Pigeon

Avian
Kakariki

Chicken
Crow

Partridge, European grey


Passerine
Pheasant, Ring-necked
Quail, Japanese

Diazepam
Diazepam

Diazepam

Diazepam
Diazepam
Diazepam
Diazepam
Diazepam
Diazepam
Diazepam
Diazepam
Diazepam
Diazepam

Diazepam
Diazepam

Dibutyltin Dilaurate
Dibutyltin Dilaurate

Dichlorophen

Dichlorvos
Dichlorvos Strip

Diclazuril
Diclazuril

Diclazuril
Diclazuril
Diclazuril
Diclazuril

Feed
PO
Feed
Feed

Feed
PO

IH
IH

PO

Feed
Feed

IV
Feed

IM-IV
PO
IM-IO-IV
IM-IV
IM
IV
NL
IM
IV
IV

IM

IV
PO

IV
IV
PO
IV

ROUTE

QD
QD
QD
QD

QD
QD

QD
QD

q10d

QD
QD

NL
Once

PRN
PRN
PRN
PRN
PRN
PRN
PRN
PRN
PRN
PRN

PRN

PRN
NL

PRN
PRN
PRN
PRN

DOSAGE
INTERVAL

B
G
B
B

G
D

E
G

E
C

E
G

G
E
E
G
D
D
D
E
E
G

D
E

D
D
E
G

891
1334
891
891

564
1438

704
1609

232

564
564

4
1386

590
1473
1688
824
1401
1533
1403
4
243
418

1432

1401
1439

1401
1401
4
481

C.I.** REFERENCE

Dose on days 0, 1, 2, 4, 6, 8 and 10 for


toxoplasmosis
For Eimeria
Give on days 0, 1, 2, 4, 6, 8 and 10
For Eimeria

Impregnated strip, 30 m minimum


For Knemidocoptes

10 day slaughter withdrawal

Add ketamine
Add ketamine
Add ketamine
Add ketamine
Add ketamine
Tranquilization particularly during anesthesia
recovery
Sedation
Add chloralose

Add ketamine
Smooth anesthesia recovery
Standing sedation
Give just prior to recovery from
tiletamine/zolazepam
Add ketamine
Anxiolytic and hyperphagic for wild fractious
species
Add ketamine, 20 to 30 minutes deep
sedation
Add ketamine

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

0.366
10
0.369
0.29-0.56

0.5-1
2.5-4
0.5-1
1-1.5
1
1-1.5
1
0.1
0.2-0.3
0.3

2.5

1
0.5

2.2
1
5
1-2

Kestrel
Ostrich
Ostrich
Ostrich

Diazepam
Diazepam
Diazepam
Diazepam

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

Chapter 9 | T H E R A P E U T I C A G E N T S

265

0.025-0.075
0.1-0.3
0.02
0.02
0.01
0.02-0.05
0.0033 g/L
0.02
0.02
2.5
25-35

5 ml

N/A

5
2-4

50
PO
1.25lmllpowder/LlllllllllDrink

Avian
Avian

Amazon, Yellow-naped
Avian
Avian
Avian
Avian
Budgerigar
Sparrow

Avian

Avian

Avian
Avian

Avian

Avian
Avian

Avian
Chicken

Raptor

Avian
Avian

Avian
Avian

Diethylstilbestrol
Diethylstilbestrol

Digoxin
Digoxin
Digoxin
Digoxin
Digoxin
Digoxin
Digoxin

Dimercaprol

Dimercaprol

Dimethyl Sulfoxide
Dimethyl Sulfoxide

Dimethyl Sulfoxide

Dimethyl Sulfoxide
Dimethyl Sulfoxide

Dimethyl Sulfoxide
Dimethyl Sulfoxide

Dimethyl Sulfoxide

Dimethylglycine
Dimethylglycine

Dimetridazole
Dimetridazole

Nebulize

Nebulize

PO

IM

PO
NL
PO
PO
Drink
PO
PO

IM
IM

PO

PO
PO

Topical

IM
Topical

QD
NL

TID
QD-BID

NL

BID-TID
NL

NL
NL

TID-QID

NL

QD-q2d

q4h

BID
NL
QD-BID
QD-BID
QD
QD
QD

NL
NL

NL

NL

DOSAGE
INTERVAL

E
E

E
E

G
B

E
G

G
D
E
E
G
A
A

E
E

704
741

1205
1435

1240

861
1342

1650
1717

1650

704

1240, 1473

1120, 1236

1033
1470
1152
1152
1323
882
882

111
1473

1463

1240

C.I.** REFERENCE

For trichomoniasis, giardiasis and


histomoniasis

Brain disorders
Immune and energy booster

Reduce swelling, vehicle to carry drugs


through skin particularly on legs

For heavy metal poisoning


Add bupivacaine, prepare 50:50 solution

Add appropriate antimicrobial, adjunct to


parenteral therapy for air sacculitis
For prolapsed phallus
Also apply topically

Add tylosin + 10 ml 0.9% saline solution

Continue BID for 10 days (or longer if


needed) for lead toxicoses
Give 5 days per week for lead toxicosis

Change daily

Anthelmintic

For arthritis

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

20
Mix 50:50

Ointment
Topical
1 ml/kg 50 % solution PO

10 ml/L

50

Raptor

Diethylcarbamazine
Citrate

PO

12.5 mg/TD

Pigeon

Diclofenac Sodium

ROUTE

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

266
C l i n i c a l Av i a n M e d i c i n e - Vo l u m e I

0.1 g/L
0.1 g/L
0.4 g/L
50
20
500 mg/kg food
0.5-1.0 g/L
125
100
40-187 mg/kg food

Finch
Lorikeet
Pigeon
Pigeon
Pigeon
Poultry
Poultry
Raptor
Raptor

Chicken

Dimetridazole
Dimetridazole
Dimetridazole
Dimetridazole
Dimetridazole
Dimetridazole
Dimetridazole
Dimetridazole
Dimetridazole

Dinitolmide

0.02-0.1
0.02-0.1
5 mg TD
0.02-0.1
0.02-0.1
0.02-0.1
0.2

0.02
2
4
2-4
2-4
2-4
4
2 mg/mg etorphine

Anseriformes
Avian
Ostrich

Psittacine
Psittacine
Raptor

Avian

Cockatiel

Avian

Avian
Avian
Avian
Psittacine
Raptor

Cassowary, Double-wattled

Dinoprost Tromethamine
Dinoprost Tromethamine
Dinoprost Tromethamine

Dinoprost Tromethamine
Dinoprost Tromethamine
Dinoprost Tromethamine

Dinoprostone
(Prostaglandin E)

Dinoprostone

Diphenhydramine HCl

Diphenhydramine HCl
Diphenhydramine HCl
Diphenhydramine HCl
Diphenhydramine HCl
Diphenhydramine HCl

Diprenorphine

NL

IM
PO
NL
PO
IM

IO

Vent

Vent

Vent
IM
Vent

IM
IM
Parenteral

IM-Topical

Feed

Drink
Drink
Drink
PO
PO
Feed
Drink
PO
PO

PO
Gavage

ROUTE

PRN

TID
BID
BID
BID
TID

NL

Once

NL

Once
Once
Once

Once
Once
Once

Once

QD

QD
QD
NL
QW
QD
QD
QD
NL
NL

NL
Once

DOSAGE
INTERVAL

E
D
E
E
G

E
E
E

E
E
G

G
E
A
E
G
C
G
D
E

E
E

1401

1554
1475
1477
1473
50

1470

1699

1474

1240
1240
1240

1240
1473
1224

1150

564

1334
1479
791
1432
232
564
585
1612
1463

924
1650

C.I.** REFERENCE

Etorphine antagonist

Give before asparaginase and doxorubicin to


minimize anaphylaxis
For anticholinesterase toxicity
Control of self-mutilation
For feather, suture and bandage picking

Precede with calcium gluconate for egg


binding, apply into cloaca, may add vitamin E
+ selenium
For egg binding

For egg binding


Also intracloacal
For caseous salpingitis, add appropriate
antimicrobials for 1 week
Apply to cloacal mucosa for egg binding
For egg binding

Apply to cloacal mucosa topically, egg


binding

No slaughter withdrawal, prophylactic

For trichomoniasis
For trichomoniasis

Prophylactic

For protozoa
For trichomoniasis, giardiasis and
histomoniasis
For cochlosomiasis

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

0.02-0.1

Dinoprost Tromethamine Anseriformes


(Prostaglandin F-2a)

50
30

Avian
Avian

Dimetridazole
Dimetridazole

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

Chapter 9 | T H E R A P E U T I C A G E N T S

267

0.3 g/L

10
5-10
5
6
20
10
0.5-1.5
20
10
5-20
0.5-1
0.5

Psittacine

Anseriformes
Avian
Avian
Avian
Avian
Falcon
Ostrich
Psittacine
Raptor
Raptor

Avian
Avian

Avian

Docusate Sodium

Doxapram HCl
Doxapram HCl
Doxapram HCl
Doxapram HCl
Doxapram HCl
Doxapram HCl
Doxapram HCl
Doxapram HCl
Doxapram HCl
Doxapram HCl

Doxepin HCl
Doxepin HCl

Doxorubicin
Doxorubicin

40-50
100
50
0.24 g/kg food
50
100
15
75-100
75-100

Doxycycline
Doxycycline**
Doxycycline**
Doxycycline
Doxycycline
Doxycycline**
Doxycycline
Doxycycline**
Doxycycline**

PO
IM
IM
Feed
PO
IM
Drink
IM-SC
IM

Feed
IM

IO

PO
PO

IV
IM-IV
IM-IO-IV
IV
IM-IO-IV
IM-IV
IV
IM-IO-IV
IM-IV
IT-IV

Drink

IV
IM

ROUTE

QD-BID
q5d-QW
q4-5d
QD
BID
q10d
QD
q5d-QW
q5d

QD
QW

q3w

BID
BID

Once
Once
NL
NL
NL
Once
PRN
NL
Once
Once

NL

PRN
PRN

DOSAGE
INTERVAL

E
A
B
D
D
B
C
E
E

A
A

E
E

D
E
E
G
E
E
G
E
E
E

B
G

111
230
1062
1150
1150
583
705
565
703

693
55

1470

111
704

1150
111, 1473
243
496
1183
1027
522
1688
1240
1359

763

447
481

C.I.** REFERENCE

Antichlamydophilial
For chlamydophilosis, may be spaced 5 to 7
days for first 4 weeks

For chlamydophilosis

For chlamydophilosis

European formulation. For


chlamydophilosis, may be spaced 5 to 7 days
for first 4 weeks

**Check current literature prior to use


Give 30 mg/m of body surface for
lymphosarcoma

Control feather picking


Or add to drinking water

For anesthetic emergencies

Also drop onto tongue for cardiac arrest

Stimulant

To aid in expelling lead or prevent


constipation following cloacal surgery

Opioid antagonist
Reverse etorphine

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

Amazon Parrot
Amazon Parrot
Amazon
Anseriformes
Anseriformes
Avian
Avian
Avian
Avian

1 g/kg food
100

Doxycycline
Amazon Parrot
Doxycycline** References Avian
followed by ** are based
on the long acting
formula)

30 mg/m2

0.05-0.06
4.5-24 mg TD

Ostrich
Ostrich

Diprenorphine
Diprenorphine

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

268
C l i n i c a l Av i a n M e d i c i n e - Vo l u m e I

Bird, Aquatic

Bird, Aquatic
Bird, Aquatic
Bustard, Houbara
Bustard, Houbara

Chicken
Chicken
Chicken
Cockatiel
Cockatiel

Cockatiel
Cockatiel

Cockatiel
Cockatoo
Cockatoo, Goffin
Cockatoo, Goffin
Cockatoo, Goffin
Macaw
Macaw, Blue and Gold
Ostrich
Parrot, Grey
Parrot, Grey
Parrot, Grey
Passerine

Passerine

Penguin
Penguin, African
Pigeon
Pigeon
Pigeon
Pigeon
Poultry
Poultry

Doxycycline

Doxycycline
Doxycycline**
Doxycycline**
Doxycycline

Doxycycline
Doxycycline
Doxycycline
Doxycycline
Doxycycline

Doxycycline
Doxycycline**

Doxycycline
Doxycycline
Doxycycline
Doxycycline
Doxycycline
Doxycycline
Doxycycline
Doxycycline
Doxycycline
Doxycycline
Doxycycline
Doxycycline

Doxycycline

Doxycycline
Doxycycline
Doxycycline **
Doxycycline**
Doxycycline
Doxycycline
Doxycycline
Doxycycline

10
20
75
75-100
25
15
0.05 g/L
0.25-0.5 g/L

1 g/kg food

40-50
1 g/kg food
25
0.4 g/L
1 g/kg mash
25
1 g/kg corn mash
10
25
0.4 g/L
1 g/kg food
0.25 g/L

1 g/kg mash
100

20
0.1 g/L
10
0.83 g/L
0.5 g/kg seed

10 g/L
75-100
100
22-44

25-50

DOSAGE (mg/kg
unless otherwise
stated)

NL
PO
IM
IM-SC
PO
Drink
Drink
Drink

Feed

PO
Feed
PO
Drink
Feed
PO
Feed
NL
PO
Drink
Feed
Drink

Feed
IM

PO
Drink
Drink
Drink
Feed

Drink
IM
IM
IV

PO

ROUTE

QD
BID
Once
q5d-QW
BID
QD
QD
QD

QD

QD
QD
BID
NL
QD
BID
QD
BID
BID
NL
QD
QD

QD
q10d

QD
NL
QD
QD
QD

QD
QW
QW
Once

QD

DOSAGE
INTERVAL

G
G
A
A
A
C
C
G

E
A
A
A
A
A
A
E
A
A
A
E

A
A

A
A
B
A
A

E
E
A
A

1353
1353
379
565
565
704
564
585

1437

111, 703
693
697
749
1639
697
730
628
697
749
1639
1437

1638
1638

762
803
1009
1638
1638

1503
1503
1240
1240

1503

C.I.** REFERENCE

Add tylosin, antimycoplasmal

With grit in diet

Add drug to food at the same time, use for


30 days for chlamydophilosis
Add drug to drink at the same time, use for
30 days for chlamydophilosis
For babesiosis

Each bird fed 100 g mash


Oviductal infection therapy

For chlamydophilosis
For chlamydophilosis, may not maintain
adequate drug plasma levels
For chlamydophilosis

For fowl cholera


For chlamydophilosis
For chlamydophilosis, may cause toxicosis

Broad spectrum, food for respiratory


infections, treat for 45 days for
chlamydophila
See above
See above
See above
Continue therapy with IM or PO dosage for
severe chlamydophilosis

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

SPECIES

DRUG NAME

Chapter 9 | T H E R A P E U T I C A G E N T S

269

0.2-0.4 g/L
0.8 g/L
0.8 g/L
55
10-40
30-50

Avian
Avian

Cockatiel
Cockatoo, Goffin
Parrot, Grey
Pigeon

Anseriformes

Avian

Avian

Avian

Bird, Aquatic

Crane, Sand Hill

Lory, Chattering

Macaw

Pigeon

Psittacine

Raptor

Raptor

Doxycycline Hyclate
Doxycycline Hyclate

Doxycycline Hyclate
Doxycycline Hyclate
Doxycycline Hyclate
Doxycycline Hyclate

Edetate Calcium
Disodium
Edetate Calcium Disodium

Edetate Calcium Disodium

Edetate Calcium Disodium

Edetate Calcium Disodium

Edetate Calcium Disodium

Edetate Calcium Disodium

Edetate Calcium Disodium

Edetate Calcium Disodium

Edetate Calcium Disodium

Edetate Calcium Disodium

Edetate Calcium Disodium

IM-IV

NL

IV

IM

IM

SC

IM

IM

IM

IM-IV

IM-IV

IM-IV

Drink
Drink
Drink
PO

Drink
Feed

IV
IM
PO
IV
IM
PO
PO

ROUTE

BID

BID

BID

BID

BID

BID

BID

BID

BID-TID

BID

QID

BID

QD
QD
QD
BID

QD
QD

NL
QW
QD
Once
NL
BID
BID

DOSAGE
INTERVAL

A
A
A
G

A
E

E
E
E
E
B
G
G

1240

1188

1240

590

40

42

1088

1478

111

1470

1221

1150

703
703
703
47

703
565

111
632
632
632
1568
94
1308

C.I.** REFERENCE

Lead and heavy metal poisoning

For lead toxicity

Lead and heavy metal poisoning

Repeat 4 days later for lead poisoning

Give 3 to 4 days per week for lead poisoning

For lead or zinc toxicosis, may use in


conjunction with penicillamine
To reduce liver lead and zinc

For lead poisoning

For chlamydophilosis

For chlamydophilosis
Antichlamydophilial

Juvenile dosage
For chlamydophilosis

Neonate dosage
Neonate dosage
Neonate dosage

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

10-40

35-50

10-40

30

35

30

35

35

20-40

20-40

0.4 g/L
200-400 mg/kg food

25-50
100
50
20
50
25
2-3.5

Psittacine
Psittacine
Psittacine
Psittacine
Raptor
Raptor
Ratite

Doxycycline
Doxycycline**
Doxycycline
Doxycycline **
Doxycycline
Doxycycline
Doxycycline

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

270
C l i n i c a l Av i a n M e d i c i n e - Vo l u m e I

2 g/L NaCl
2 g/L NaCl
0.1-1% solution
5
0.2% solution
10% solution
7.5-15
15
0.5 mg/kg food
10
10-15
10
5-15
30
10 g/L

Avian
Psittacine
Psittacine
Raptor
Raptor
Ratite

Amazon Parrot
Amazon
Amazon, Blue-fronted
Amazon, Red Lored
Anseriformes
Aracari, Black-necked
Avian
Avian
Avian

Avian
Avian
Avian

Bird, Aquatic
Budgerigar
Bustard, Houbara
Chicken
Duck, Muscovy
Duck, Pekin
Gull
Hawk, Red-tailed
Hornbill, Great
Lory, Red
Ostrich
Owl, Great-horned
Parrot, Grey
Parrot, Grey
Penguin, Rockhopper
Pheasant
Pheasant, Chinese Ringneck
Pigeon

Enilconazole
Enilconazole
Enilconazole
Enilconazole
Enilconazole
Enilconazole

Enrofloxacin
Enrofloxacin
Enrofloxacin
Enrofloxacin
Enrofloxacin
Enrofloxacin
Enrofloxacin
Enrofloxacin
Enrofloxacin

Enrofloxacin
Enrofloxacin
Enrofloxacin

Enrofloxacin
Enrofloxacin
Enrofloxacin
Enrofloxacin
Enrofloxacin
Enrofloxacin
Enrofloxacin
Enrofloxacin
Enrofloxacin
Enrofloxacin
Enrofloxacin
Enrofloxacin
Enrofloxacin
Enrofloxacin
Enrofloxacin
Enrofloxacin
Enrofloxacin
Enrofloxacin

IM
Feed
IM-IV-PO
Drink
Drink
Drink
IM
IV
PO
PO
PO
IM-PO
Drink
Feed
PO
IM-PO
IM
IM-SC

Feed
Drink
PO

IM-PO
IM
Feed
IM
IM-PO
PO
IM-PO-SC
PO
Nebulize

Topical
Nebulize
IT
IT
Topical
Flush

ROUTE

BID
Once
BID
NL
QD
QD
BID
QD
BID
BID
TID
BID
QD
Once
QD
NL
QD
QD

QD
NL
QD

QD-BID
QD
Once
BID
BID
BID
QD-BID
NL
TID-QID

NL
BID
NL
QD
BID
NL

DOSAGE
INTERVAL

E
A
A
A
B
A
E
A
G
G
G
G
A
A
G
G
G
A

F
F
G

A
A
A
G
D
G
A
E
E

E
G
E
E
E
G

1478
920
790
811
842
854
1357
978
1587
1621
418
173
921
921
1646
678
1296
179

916
916
580

1473
749
858
700
1150, 1358
1367
916
1492
1650

924
1034
1240
1240
1240
1224

C.I.** REFERENCE

Continue therapy orally

Add clindamycin or cephalothin


For salmonellosis
Higher blood levels in neonates

Pulse dose for 4 hours each day


For Pasteurella and coliforms

Add ethambutol + rifampin,


antimycobacterial
Post-trauma infections
For chlamydophilosis

For Mycoplasma, Chlamydophila


Add dimethyl sulfoxide, adjunct to parenteral
therapy for air sacculitis

Pre-surgical

For chlamydophila
2.5% concentration

For mycotic dermatosis

Dilute 1:10

For skin mycosis


Dilute 100 mg/ml 1:50 in normal saline

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

5
0.5 g/L
0.5 g/kg food
9
20
7.5
15

30
30
15-30
10
15
10
10
5
10-20
15

0.25-1 g/kg food


0.05-0.5 g/L
15

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

Chapter 9 | T H E R A P E U T I C A G E N T S

271

1.5-2.5
0.1

0.1
0.06

0.125 g/L
25
100
200 mg/kg
10-20 g/L
0.102 g/L
0.2 g/kg food
0.125 g/L
100
2.2 g/L
0.25 g/L
10-20
50-100
44-88
10-20

Pigeon
Pigeon
Pigeon
Poultry
Psittacine
Psittacine
Psittacine
Raptor

Ratite

Avian

Avian

Avian

Avian
Avian
Avian
Avian
Avian
Chicken
Finch
Finch
Pigeon
Pigeon
Poultry
Poultry
Poultry
Psittacine
Psittacine

Psittacine

Enrofloxacin
Enrofloxacin
Enrofloxacin
Enrofloxacin
Enrofloxacin
Enrofloxacin
Enrofloxacin
Enrofloxacin

Enrofloxacin

Epinephrine

Epoetin Alfa

Ergonovine Maleate

Erythromycin
Erythromycin
Erythromycin
Erythromycin
Erythromycin
Erythromycin
Erythromycin
Erythromycin
Erythromycin
Erythromycin
Erythromycin
Erythromycin
Erythromycin
Erythromycin
Erythromycin

Erythromycin

BID

QD-BID
QD
BID
BID
QD
NL
NL
BID

QD
QD-BID

DOSAGE
INTERVAL

ParenteralPO

Drink
IM
PO
Feed
Nebulize
Drink
Feed
Drink
PO
Drink
Feed
Drink
NL
PO
PO

IM

SC

BID

NL
QD
NL
QD
TD
QD
QD
QD
NL
QD
QD
QD
BID
BID
BID

Once

q2-3d

IO-IP-IT-IV NL

PO-SC

PO
IM-IV-POSC
IM-PO-SC
Drink
PO
NL
PO
Drink
IM
IM-PO

ROUTE

E
E
E
E
E
A
E
E
A
E
C
C
G
E
E

A
A
A
G
A
B
E
E

A
A

1473

111
565
704
704
704
544
1572
1572
1055
704
564
705
585
741
1240

111, 1473, 1650

1151

1473

1308

919
919
1473
585
179
750
632
1240

179
866

C.I.** REFERENCE

For sinusitis
For mycoplasmal sinusitis and air sacculitis

Erythrocin Soluble, 5 g per teaspoon

Soft food
Diluted in 15 ml 0.9% saline solution
Chick dosage

With or without calcium gluconate for egg


binding

For anemia

Neonate dosage, may cause joint defects


Broad spectrum including Pseudomonas,
Klebsiella, Mycoplasma
For Gram negative infections

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

10-20

10-20
5
5
15
2.5-20
11-17.5
10-20
15

10
5-10

Pigeon
Pigeon

Enrofloxacin
Enrofloxacin

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

272
C l i n i c a l Av i a n M e d i c i n e - Vo l u m e I

10-15
30
30
15
30

30
15-20
20
0.15
0.04-0.07
0.04
1:250 dilution

1:250 Dilution

0.22 ml/kg

0.11 ml/kg

20
5
30
20

Avian

Amazon, Yellow-cheeked
Avian
Avian
Avian

Avian

Crane, Whooping
Psittacine
Raptor

Cassowary, Double-wattled
Ostrich
Ostrich

Avian

Avian

Avian
Avian

Raptor

Psittacine

Psittacine

Ostrich
Ostrich
Pigeon

Anseriformes

Estradiol

Ethambutol HCl
Ethambutol HCl
Ethambutol HCl
Ethambutol HCl

Ethambutol HCl

Ethambutol HCl
Ethambutol HCl
Ethambutol HCl

Etorphine
Etorphine
Etorphine

F10

F10

F10
F10

F10

Fatty Acids, Omega

Fatty Acids, Omega

Febantel
Febantel
Febantel

Fenbendazole

PO

NL
PO
PO

PO

PO

Nebulize

Nebulize
Nebulize

Topical

Nebulize

IM
IM
IM

PO
PO
PO

PO

NL
PO
PO
PO

IM

PO

ROUTE

Once

NL
NL
q3w

QD

NL

BID-TID

TID
BID

QD

QD-BID

PRN
PRN
PRN

QD
BID
BID

BID

QD
QD
BID
QD

QW

TID

DOSAGE
INTERVAL

C
G
A

B
G

G
B
B

G
E
E

G
D
E
E

1150

283
481
888

1263

1756

742

1465
1268

1302

1197

447
447
447

207
1240
1240

55

713
1470
1473
1650

677

1308

C.I.** REFERENCE

Control nematodes

For ascarids and capillaria

Add aspirin, use < 6:1 ratio omega 6:omega


3, use until renal histology normalizes for
renal disease
Mix 5:1 N-6:N-3 omega fatty acids for
glomerulonephritis or acute pancreatitis

Add omega interferon, prevents secondary


infection
Add itraconazole, 15 to 30 minutes per day
for mild aspergillosis

Nebulize as antifungal, antichlamydophilial


and antibacterial
Daily spray onto feathers for yeast and
supplement to feather picking therapy

Add acepromazine
Add acepromazine
Add acepromazine + xylazine

Add enrofloxacin + rifabutin for


mycobacteriosis
Add rifampin + streptomycin for
mycobacteriosis
Add rifampin
For mycobacteriosis

Add rifampin + isoniazid

Induce molting X 4 weeks

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

1:125 dilution
1:125 Dilution

1:200 dilution

10

5-10

Ratite

Erythromycin

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

Chapter 9 | T H E R A P E U T I C A G E N T S

273

Anseriformes
Avian
Avian
Avian
Avian
Avian
Avian

Avian

Bird, Aquatic
Bird, Aquatic
Bird, Aquatic
Bustard
Bustard, Houbara
Cockatiels
Crane
Crane

Falcon
Finch
Grouse
Gull
Gull
Ostrich
Ostrich
Ostrich
Parakeet, Australian
Partridge
Partridge
Penguin
Pheasant
Pheasant
Pigeon
Pigeon
Pigeon
Pigeon
Pigeon
Pigeon
Pigeon

Fenbendazole
Fenbendazole
Fenbendazole
Fenbendazole
Fenbendazole
Fenbendazole
Fenbendazole

Fenbendazole

Fenbendazole
Fenbendazole
Fenbendazole
Fenbendazole
Fenbendazole
Fendendazole
Fenbendazole
Fenbendazole

Fenbendazole
Fenbendazole
Fenbendazole
Fenbendazole
Fenbendazole
Fenbendazole
Fenbendazole
Fenbendazole
Fenbendazole
Fenbendazole
Fenbendazole
Fenbendazole
Fenbendazole
Fenbendazole
Fenbendazole
Fenbendazole
Fenbendazole
Fenbendazole
Fenbendazole
Fenbendazole
Fenbendazole

20
10-25
0.5-0.7
50
25
15
30
15
50
8
12
50
12
8
16
20
20-50
8
7.5
7.5-20
10-12

22
50
100
30
25
N/A
100
50-100

20-100

5-10
25
100
2
20-50
20-50
50

DOSAGE (mg/kg
unless otherwise
stated)

QD
QD
QD
QD
q2w
NL
NL
NL
Once
QD
Once
NL
Once
QD
Once
QD
QD
Once
Once
Once
QD

QD
QD

PO
PO
PO
PO
Feed
PO
PO
PO
PO
PO
Gavage
Feed
Feed
PO
PO
PO
PO
PO
PO
PO
PO
PO
PO

NL
QD
q2w
Once
Once

Once

QD
QD
q2w
QD
q10d
QD
QD

DOSAGE
INTERVAL

NL
PO
PO
PO
PO

PO

PO
NL
NL
PO
PO
PO
PO

ROUTE

E
E
C
E
E
B
B
G
E
C
C
E
C
C
C
C
E
E
E
G
G

E
E
E
E
G
G
E
E

E
D
D
D
E
E
E

1240
1572
704
1357
1357
524
526
481
1186
704
704
1478
706
706
704
706
1240
1240
1432
232
260

629
1361

1478
1503
1503
1240
932

57

111, 1473
1221
1221
1470
111
111
1617

C.I.** REFERENCE

For gastrointestinal roundworms


For capillariasis
At 8 weeks of age

For roundworms
For Capillaria
For Syngamus, Heterakis , ascarids
For nematodes and flukes

For Trichostrongylus
For capillariasis
For ascaridiasis
With or without resorantel
Add resorantel

Prophylaxis for round worms


May have lethal reaction
Repeat q2w as needed
Repeat in 2 weeks for gapeworms and
capillarids
For Serratospiculum

Repeat in 2 weeks for ascarids

Repeat in 2 weeks for capillariasis


For capillariasis
For liver parasitic disease
For ascarids
For flukes and capillaria
For ascarids, may need 5-day treatment for
capillaria, repeat in 2 weeks,
Avoid during breeding season and molting

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

SPECIES

DRUG NAME

274
C l i n i c a l Av i a n M e d i c i n e - Vo l u m e I

20-50
15
100
50
10-50
30-50
25
15
0.2

N/A
7.5-15
N/A

N/A
0.022 ml/kg body wt. Feed
0.1-0.2 ml/kg

125
250
0.24 mg/kg feed
30-60 g/ton feed

Psittacine
Psittacine
Psittacine
Psittacine
Raptor
Raptor
Raptor
Ratite

Avian

Avian

Avian
Canary

Dove, Duck
Raptor

Raptor

Amazon, Yellow-naped

Avian

Hawk
Raptor

Anseriformes
Galliformes

Fentanyl Citrate

Ferric Subsulfate

Fipronil
Fipronil

Fipronil
Fipronil

Fipronil

Flax Seed Oil

Flax Seed Oil

Floxacillin
Floxacillin

Flubendazole
Flubendazole

Feed
Feed

PO
PO

PO

Topical

NL
Topical

QD
QD

BID
NL

NL

QD

Once

Once
Once

Once
Once

PRN

NL

r2w
QD
q2w
QD
q10d
Once
QD
NL

QD
q10d

DOSAGE
INTERVAL

D
C

G
E

G
B

G
G

E
E
E
E
E
E
E
G

G
G

1150
704, 706

1110
1463

1682

1033

1359

1729
1568

1729
1729

1473

1341

763
1240
1613
1613
1132
1132
1159
418

590
1208

C.I.** REFERENCE

Control nematodes
For gastrointestinal roundworms, gapeworms
and tapeworms

For bacterial infections

Mix 1:4 with corn oil prior to dosing for renal


disease

Dilute 1:4 with corn oil

For ectoparasites

For wild injured raptors with ectoparasites

For larger birds


Spray on gloved finger and rub under wings
and on dorsal and ventral surfaces of body
for red mites

For hemorrhage

Some hyperactivity for first 15 to 30 minutes

May medicate feed for 7 days


For ascaridiasis
For capillariasis
For ascaridiasis
For flukes
For nematodes
With or without resorantel

For ascarids or Capillaria, not for use during


molting

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

7.5-15
Light Spray

NL
Topical

Topical

SC

PO
PO
PO
PO
NL
NL
PO
PO

PO
PO

Fenbendazole
Fenbendazole
Fenbendazole
Fenbendazole
Fenbendazole
Fenbendazole
Fenbendazole
Fenbendazole

50
15

Pigeon
Pigeon

ROUTE

Fenbendazole
Fenbendazole

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

Chapter 9 | T H E R A P E U T I C A G E N T S

275

20

30
5-10
5-15
2-5
2-5
5
2-5
250
50-100

Amazon Parrot

Avian
Avian
Avian
Avian
Avian
Bird, Aquatic

Bird, Aquatic
Bird, Aquatic
Chicken

Penguin, African
Pigeon
Psittacine
Psittacine
Raptor
Raptor
Raptor

Avian
Avian

Avian

Avian
Avian
Bird, Aquatic
Bird, Aquatic
Hornbill, Great
Penguin, African
Psittacine

Psittacine

Fluconazole

Fluconazole
Fluconazole
Fluconazole
Fluconazole
Fluconazole
Fluconazole

Fluconazole
Fluconazole
Fluconazole

Fluconazole
Fluconazole
Fluconazole
Fluconazole
Fluconazole
Fluconazole
Fluconazole

Flucytosine
Flucytosine

Flucytosine

Flucytosine
Flucytosine
Flucytosine
Flucytosine
Flucytosine
Flucytosine
Flucytosine

Flucytosine

PO

PO
PO
NL
PO
PO
PO
PO

PO

PO
PO

PO
PO
PO
PO
PO
PO
PO

PO
PO
Gavage

NL
PO
IV-PO
IV-PO
IV-PO
PO

IV-PO

ROUTE

BID

BID
BID
BID
TID
BID
BID
BID

TID

BID
BID

BID
BID
BID
QD
QD
QD
QD

BID
BID
BID

QD
q2d
QD
q2d
BID
QD

q2d

DOSAGE
INTERVAL

E
E
E
E
G
G
D

D
D

G
G
D
G
E
E
E

E
E
G

D
D
D
D
D
E

1330

626
1492
1503
1503
1587
1353
1330

626

1221
674, 1330

128
56
1446
697
1240
1359
1400

1503
1559
1348

1221
1221
1330
1330
1330
1478

1330

C.I.** REFERENCE

May give long-term


For Aspergillus or Candida prophylaxis, add
amphotericin B or azoles for therapy

Aspergillosis prophylaxis
For aspergillosis adjunct therapy

Add IV and IT amphotericin B for


aspergillosis therapy
Aspergillus prophylaxis

For candidiasis
For Aspergillus or Candida prophylaxis, add
amphotericin B or azoles for therapy

For generalized aspergillosis


For candidiasis
Aspergillosis

Prophylaxis

For macrorhabdosis (formerly megabacteria


or avian gastric yeast), toxic to budgerigars

Adult doase
Juvenile dose
For prevention of aspergillosis, may also
nebulize

For ketoconazole-resistant Candida , tissuebased yeasts, eye, cerebral spinal, long-term


Aspergillus
For cryptococcosis
For candidiasis

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

100-250

50-60
20-50
50-60
100
250
250
75-120

40-50

8
15
100

8
20
5
20
4-6
15

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

276
C l i n i c a l Av i a n M e d i c i n e - Vo l u m e I

80-100
50-75
0.05
0.1
0.05
0.04
1
1-10
1-10

2
5
5
1-10
1-10
2-10
1
1
0.4
0.47 mg./kcal
15-20
0.125 g/L
0.4 g/L

15-20

Raptor

Ratite
Swan

Anseriformes

Avian
Avian
Pigeon

Anseriformes
Anseriformes
Avian

Bird, Aquatic

Bustard, Houbara
Duck, Mallard
Duck, Mallard
Pigeon
Psittacine
Raptor

Avian

Avian
Psittacine

Avian
Pigeon
Pigeon
Pigeon

Pigeon

Flucytosine

Flucytosine
Flucytosine

Flumazenil

Flumazenil
Flumazenil
Flumazenil

Flunixin Meglumine
Flunixin Meglumine
Flunixin Meglumine

Flunixin Meglumine

Flunixin Meglumine
Flunixin Meglumine
Flunixin Meglumine
Flunixin Meglumine
Flunixin Meglumine
Flunixin Meglumine

Fluoxetine HCl

Fluoxetine HCl
Fluoxetine HCl

Furaltadone
Furaltadone
Furaltadone
Furaltadone

Furazolidone +
Furaltadone

PO

PO
PO
Drink
Drink

NL
PO

NL

NL
NL
IM
IM-IV
IM
IM

IM

SC
IM
IM

NL
IV
IM

IV

PO
PO

PO

PO

ROUTE

QD

QD
QD
QD
QD

QD
QD

NL

NL
NL
BID
QD
NL
QD

QD

QD
NL
QD

PRN
PRN
PRN

PRN

BID
BID

BID

BID

DOSAGE
INTERVAL

E
E
E
E

E
D

G
A
A
E
E
D

E
E
D

E
E
G

G
G

1061

1180
565
1492, 1650
1240

1477
1446

1186

1594
1339
1490
1432
1240
1400

1503

1190
1150
1533

1481
1533
1644

1503, 1533

1308
86, 697

1330

1178

C.I.** REFERENCE

For salmonellosis
Add tetracycline for trichomoniasis and
hexamitiasis, not for adults feeding young <
10 days old

For behavioral problems such as feather


picking
For feather picking
For behavioral feather picking

Swelling in foot deformity of neonate


Residual physiological effect 12 hours
For frostbite

May cause renal ischemia at higher dosages

For joint lameness


May cause renal ischemia at higher dosages

Reverse midazolam

Add atipamezole to reverse ketamine +


medetomidine + midazolam
Reverse benzodiazepines

Add IT and IV amphotericin B + rifampin


for aspergillosis
For aspergillus or Candida prophylaxis birds
> 500 g, add H1176amphotericin B or azoles
for therapy

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

1-10

60

120

Raptor

Flucytosine

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

Chapter 9 | T H E R A P E U T I C A G E N T S

277

0.15
0.165
0.1-0.2

0.5-3
2.2
0.15-2
1.5
1
1.5
1.5
2.2
2% ointment

0.25 mmol/kg

10
5-10
5 g/L
4
5-10

Amazon, Yellow-naped
Avian
Avian

Avian
Avian
Avian
Avian

Pigeon
Pigeon
Psittacine
Raptor
Raptor
Raptor
Raptor
Secretary Bird

Avian

Avian

Avian
Avian
Avian
Avian
Avian

Avian
Avian
Avian
Avian
Bustard

Chicken
Chicken

Furosemide
Furosemide
Furosemide

Furosemide
Furosemide
Furosemide
Furosemide

Furosemide
Furosemide
Furosemide
Furosemide
Furosemide
Furosemide
Furosemide
Furosemide

Fusidate Sodium

Gadopentetate
Dimeglumine

Gentamicin Sulfate
Gentamicin Sulfate
Gentamicin Sulfate
Gentamicin Sulfate
Gentamicin Sulfate

Gentamicin Sulfate
Gentamicin Sulfate
Gentamicin Sulfate
Gentamicin Sulfate
Gentamicin Sulfate

Gentamicin Sulfate
Gentamicin Sulfate

IM
IM

Flush
IM
IM
IM
IM

IT
IM
Nebulize
IM
NL

IV

Topical

PO
IM-IV-PO
IM-SC
IM
IM-IV
IM
IM
IM

IM
IM-SC
IM
NL

PO
IM
IM-PO

ROUTE

TID
BID

BID
BID
QD-BID
QD-BID
QD-BID

QD
BID-TID
TID
NL
QD

Once

BID

BID-TID
BID
QD-BID
QID
PRN
TID-QID
PRN
BID

QD-BID
QD-BID
BID
QD-BID

BID
BID
QD-BID

DOSAGE
INTERVAL

A
A

E
E
E
E
E

E
E
E
E
E

G
G
E
E
E
E
G
G

E
E
E
E

G
G
E

715
1056

1183
1434
1492
1650
1240

704
704
741, 924
924
1170

1754

1240

590
590
1240
1240
1359
1400
234
41

1650
111, 1470
1431
1470

1033
1309
1152

C.I.** REFERENCE

For roosters

For resistant organisms


For first 3 days of life to prevent yolk sac
infections after assisted hatch

For sinusitis or airsacculitis


For Pseudomonas , nephrotoxic
Relatively renal toxic particularly if
dehydrated
Nasal or sinus

For head magnetic resonance imaging studies

For mild/early bumblefoot and other skin


lesions, may penetrate intact skin, effective
against Staph aureus

For congestive heart failure with liver disease

Diuretic, lories sensitive


For diuresis, risk of toxicosis especially in
small birds
For ascites and edema, not for lorikeets

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

1.5
2

5 g/L
2.5
3-5
3-5
5

0.15-2
0.15-2
0.1-0.2
1-2

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

278
C l i n i c a l Av i a n M e d i c i n e - Vo l u m e I

Drink
PO

Parenteral

IM

IM

PO

Drink

PO

Drink

Topical

IM
IM
IM
IM
IM
IM
IM
IM
IM
IM
IM
IM
IT
IM
IM
IM
IM

ROUTE

QD
QD

q3-4d

QD

PRN

NL

QD

TID

QD

NL

BID-QID
TID
QID
BID-QID
TID
BID
TID
TID
TID
QID
BID-QID
BID-TID
QD
QID
TID
QD
BID

DOSAGE
INTERVAL

G
E

A
A
A
A
A
A
A
A
A
A
A
E
E
A
A
G
A

531, 1308
1240

894

1474

1644

1463

1720

1205

1726

1240

1143
458
847
1143
418
847
714
714
458
847
1143
565
741
458
565, 714
1308
880

C.I.** REFERENCE

For dermatophytosis

Treat chronic egg laying, inject day one, on


day 3 if egg, on day 7 if second egg, use up to
3-6 w
Increase spermiation and early puberty in
ganders

Add midazolam for anesthesia premed

For impaction, may give cloacally

For polyuria/polydipsia

For joint disease

Crush tablet into water for diabetes mellitus

Excellent for crop or skin fold candidiasis in


chicks

May cause visceral gout

Add carbenicillin for pneumonia

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

30-50
10

Ostrich
Pigeon

0.01

Pigeon

Glycopyrrolate

Griseofulvin
Griseofulvin

< 5 ml/kg

Raptor

Glycerin

0.5 mg TD

0.00125-0.0025 g/L

Cockatiel

Glyburide

Goose

10 drops/kg

Avian

Glucosamine Sulfate

Gonadotropin, Chorionic

0.05 g/L

Cockatoo, Rose-breasted

Glipizide

500-1000 ug/kg

N/A

Macaw, Hyacinth

Gentian Violet

Gonadotropin, Chorionic Avian

10
5
5
10
5
2.5
2.5
2.5
5
10
20
10
5-10
10
2.5
5
3

Chicken
Crane
Duck
Duck, Eagle, Macaw, Owl
Emu
Emu
Hawk, Red-tailed
Owl, Great-horned
Pheasant
Pigeon
Pigeon
Psittacine
Psittacine
Quail
Raptor
Ratite
Turkey

Gentamicin Sulfate
Gentamicin Sulfate
Gentamicin Sulfate
Gentamicin Sulfate
Gentamicin Sulfate
Gentamicin Sulfate
Gentamicin Sulfate
Gentamicin Sulfate
Gentamicin Sulfate
Gentamicin Sulfate
Gentamicin Sulfate
Gentamicin Sulfate
Gentamicin Sulfate
Gentamicin Sulfate
Gentamicin Sulfate
Gentamicin Sulfate
Gentamicin Sulfate

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

Chapter 9 | T H E R A P E U T I C A G E N T S

279

0.1
0.17

1-2
0.2
0.4
N/A
N/A
40-50 U/kg

0.1 ml of 1000U/ml
1.0 ml of 1000U/ml
55
1 ml/kg
1 ml/kg
10-15 ml/kg

Avian
Avian

Avian
Avian
Avian

Avian
Avian
Avian
Avian

Parrot, Quaker
Psittacine

Psittacine
Psittacine
Psittacine

Avian
Pigeon

Avian

Avian
Avian
Swan

Avian
Psittacine

Avian

Avian

Haloperidol
Haloperidol

Haloperidol
Haloperidol
Haloperidol

Haloperidol
Haloperidol
Haloperidol
Haloperidol

Haloperidol
Haloperidol

Haloperidol
Haloperidol
Haloperidol

Halothane
Halothane

Heparin Sodium

Heparin Sodium
Heparin Sodium
Heparin Sodium

Hepasan
Hepasan

Hetastarch

Hetastarch

IV

IV

PO
PO

Nebulize
Topical
IV

IV

IH
IH

IM
PO
PO

PO
PO

IM
PO
NL
PO

Drink
Drink
NL

PO
Drink

Feed
Feed

ROUTE

TID

TID

QD
QD

QD
QD
Once

Once

PRN
PRN

q2-3w
BID
QD

BID
BID

q2-3w
QD
NL
BID

QD
QD
NL

BID
QD

QD
QD

DOSAGE
INTERVAL

G
G

G
G
G

E
E

E
E
E

E
E

E
E
E
E

E
E
E

D
E

C
E

1151

1650

1035
1722

1705
1705
1707

1151

1617
1432

111
111
1240

1492
111

1431
1431
1477
1492

704
704
1186

1475
704

705
564

C.I.** REFERENCE

For hypoproteinemia

For emergency care, reduce crystalloid fluids

For liver disease


Liver support

Add aminophylline, dexamethasone Na


phosphate, fluids, oxygen for
polytetraflouroethylene gas poison
Add to 6.5 ml saline
Add aloe vera
Emaciated near death

Induction, maintain with 1-1.5%


1.5-3% maintenance

For feather picking

For feather picking and self-mutilation


Control feather picking and mutilation, birds
over 1 kg
Control feather picking and mutilation

For self-mutilation
For birds < 1 kg for feather picking and selfmutilation, most effective in cockatoos

Maintenance dose
For behavioral problems such as feather
picking

Body weight less than 1 kg, gradually increase


dosage to 0.9 mg/kg

For coccidial prophylaxis


Seven day slaughter withdrawal

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

10-15 ml/kg

0.08
0.15

1-2
0.2-0.4
0.1-0.15
0.2

0.2
0.4
0.4

3 g/ton food

Poultry
Chicken

Halofuginon HBr
Halofuginon HBr

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

280
C l i n i c a l Av i a n M e d i c i n e - Vo l u m e I

Hawk, Red-tailed

Hetastarch

10

4 tablets/L

2
2

10 drops/kg
7
7
cream

0.4
2
0.4

0.01-0.1 U TD

Avian

Pigeon

Avian
Psittacine

Avian

Raptor

Raptor

Amazon, Blue-fronted

Avian
Chicken
Avian

Avian

Avian
Budgerigar
Budgerigar
Psittacine

Hydrocortisone Sodium
Succinate

Hydroxychloroquine
Sulfate

Hydroxyzine HCl
Hydroxyzine HCl

Hypericum

Imidacloprid

Imidocarb HCl

Imiquimod

Indomethacin
Indomethacin
Indomethacin, Copper

Insulin, NPH

Insulin, NPH
Insulin, NPH
Insulin, NPH
Insulin, NPH

IM
IM
IM
IM

Parenteral

IM
PO
IM

Vent

NL

IT-IV

PO

PO
PO

Drink

IV

SC
Flush
Nebulize
IV

IV

IV

ROUTE

QD
BID
PRN
PRN

NL

NL
NL
QD

q2-3d

q3w

NL

TID

TID
TID

NL

NL

NL
NL
NL
NL

q2m

NL

DOSAGE
INTERVAL

G
E
G
G

E
A
E

G
D

G
G
G
G

1325
1326
58
58, 88

1650

1232
772
1492

1281

1359

1359

1205

1324
1446

590

1470

1103
1719
1719
1719

1587

1626

C.I.** REFERENCE

For diabetes mellitus in birds larger than


budgerigar
For diabetes, monitor blood glucose
For diabetes

Effective for 8-10 hours


For acute/chronic inflammation from
trauma, infection or organ dysfunction

For cloacal papillomatosis, apply to cloacal


surface

For babesiosis

For babesiosis

For feather picking, anxiety

For pruritis
For hypersensitivity-triggered feather picking

Change daily

For lead toxicity and severe infection with


liver disease

Mix with fluids to aid in absorption


Mix into nasal and sinus flushes
Mix into nebulization fluid
For egg yolk stroke

For squamous cell carcinoma

Supportive therapy post-trauma

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

0.07 U/kg
0.067-3.3 U/kg
0.002 U TD
0.01-0.1 U TD

150 U/L fluids


1.5 KIU/L
1.5 KIU/L
1.5 KIU/L

Avian
Avian
Avian
Avian

0.3

10 ml/kg

DOSAGE (mg/kg
unless otherwise
stated)

Hyaluronidase
Hyaluronidase
Hyaluronidase
Hyaluronidase

Hexyl Pyropheoborbide-a Hornbill, Great

SPECIES

DRUG NAME

Chapter 9 | T H E R A P E U T I C A G E N T S

281

15 KIU/m

1000 KIU TD
4 drops solution/L
4 drops/L 7% soln
N/A

N/A
700-800
240
0.8-1.2

0.125 g/L
0.250 g/L
0.232 g/L
10
10
10
10
N/A
30
30
15

Avian

Avian

Avian

Avian

Raptor

Avian

Avian

Raptor

Avian

Cockatiel

Avian

Avian
Pigeon
Psittacine

Anseriformes
Avian
Psittacine
Raptor

Avian

Amazon, Yellow-cheeked
Avian
Avian

Interferon, Alpha

Interferon, Omega

Interferon, Omega

Iodine, Lugol's

Iodine, Lugol's

Iodophor

Iodophor

Iodophor

Iohexol

Iohexol

Iopamidol

Ipronidazole
Ipronidazole
Ipronidazole

Iron Dextran
Iron Dextran
Iron Dextran
Iron Dextran

Isoflurane

Isoniazid
Isoniazid
Isoniazid

NL
PO
PO

IH

IM
IM
IM
IM

Drink
Drink
PO

IN

PO

IV

Topical

Topical

Topical

Drink

Drink

Parenteral

IM

SC

IM
IM

ROUTE

QD
QD
BID

PRN

QW
QW
QW-q10d
Once

QD
QD
NL

NL

NL

NL

NL

NL

PRN

QD

NL

QD-BID

q2d

q2d

QD
PRN

DOSAGE
INTERVAL

G
D
E

D
G
E
E

E
G
E

E
G

713
1470
1473

1483

1150
62
1240
1400

111, 741
590
111

1270

1623

1182

1400

1240

1151

1612

1186

1268

1465

1470

1180
58

C.I.** REFERENCE

Add ethambutol + rifampin, antibacterial


Add ethambutol + rifampin, antibacterial
Antiparasitic

Maintain 1.5-3%

Hemopoiesis
For iron-deficiency anemia

For hemopoiesis

Change daily

Use 20% concentration, sinus contrast study,


flush with saline when completed

Use 70-80% iodine concentration for


urography

Use 0.5-1% solution for wound debridement


and flushing
For wounds, apply and wash off after 3
minutes, very safe
For wounds, wash off within 5 minutes

Used to keep drinking water uncontaminated

Give 15, 000 Units/m of body surface for


lymphosarcoma
Add F10 for circovirus prevention and
limited effectiveness therapy of 90 days
Add F10 for circovirus therapy

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

N/A

1000 KIU TD

0.0013 mg/kcal
0.1-0.5 U TD

Avian
Toucan, Toco

Insulin, Regular
Insulin, Zinc Suspension

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

282
C l i n i c a l Av i a n M e d i c i n e - Vo l u m e I

5-10
10

6-10
0.2

Raptor

Amazon Parrot

Amazon, Blue-fronted

Anseriformes
Anseriformes
Avian
Avian
Bird, Aquatic
Bird, Aquatic
Chicken

Cockatiel

Crane

Crane
Emu
Falcon
Gull
Penguin
Pigeon
Pigeon

Psittacine
Psittacine

Raptor

Raptor

Ratite

Anseriformes

Avian

Isoxuprine HCl

Itraconazole

Itraconazole

Itraconazole
Itraconazole
Itraconazole
Itraconazole
Itraconazole
Itraconazole
Itraconazole

Itraconazole

Itraconazole

Itraconazole
Itraconazole
Itraconazole
Itraconazole
Itraconazole
Itraconazole
Itraconazole

Itraconazole
Itraconazole

Itraconazole

Itraconazole

Itraconazole

Ivermectin

Ivermectin

IM

PO-SC

PO

PO

NL

NL
PO

PO
PO
PO
PO
NL
PO
PO

PO

PO

PO
PO
PO
NL
PO
PO
PO

PO

PO

PO

ROUTE

r10d

Once

QD

BID

BID

QD
BID

BID
QD
QD
QD
BID
BID
BID

BID

QD

BID
QD
QD
BID
QD
QD
BID

BID

QD

QD

DOSAGE
INTERVAL

A
D

E
G
G
E
G
A
A

E
G
A
E
E
E
A

Continue QD for 4 months for


asymptomatic cases of aspergillosis
Add amphotericin B or enilconazole + F10
for mild aspergillosis
Reduce dosage if neurologic signs occur

For respiratory disease, this dosage may be


toxic
For aspergillosis
For cutaneous cryptococcosis or aspergillosis

Aspergillosis therapy long-term

For aspergillosis

Dissolve 100 mg capsule 2 ml HCl + 18 ml


orange juice for candidiasis
Add enrofloxacin + clotrimazole for
aspergillosis

For aspergillosis prophylaxis


For aspergillosis prophylaxis
Add miconazole for epidermal Aspergillus and
Alternaria cysts after surgical removal

Dissolve in 0.1N HCl, dilute with orange


juice to tube feed
Continue once daily for duration of therapy

For wing tip edema

COMMENTS (see references for


duration, precautions and
contraindications)

741, 924

1150, 1190, 1240 Control nematodes and nasal or duck leeches

1308

742

1188

1424
1446

1361
16
746
1357
1353
709
709

1189

1330

1473
708
577
1239
1503
1559
1376

1739

16

1359, 1400

C.I.** REFERENCE

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

0.2

10

5-10

10
5-10

5-10
5-10
10-20
5
10
6
26

10

5-10
10
10
5-10
20
15
10

5-10

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

Chapter 9 | T H E R A P E U T I C A G E N T S

283

0.2
0.4
0.2
0.2
0.2
0.2
20-40
10-20
20-40
2 ml/kg
67 drops/kg
10-20
25

Psittacine
Raptor
Raptor
Raptor
Ratite
Stork, Saddle-billed

Anseriformes
Avian
Ratite

Psittacine
Raptor

Amazon Parrot
Anseriformes

Anseriformes

Avian
Avian

Avian
Avian
Avian

Ivermectin
Ivermectin
Ivermectin
Ivermectin
Ivermectin
Ivermectin

Kanamycin Sulfate
Kanamycin Sulfate
Kanamycin Sulfate

Kaolin + Pectin
Kaolin + Pectin

Ketamine HCl
Ketamine HCl

Ketamine HCl

Ketamine HCl
Ketamine HCl

Ketamine HCl
Ketamine HCl
Ketamine HCl

IM
IM
IM

NL
IM

IV

IM
NL

PO
PO

IM
IM
IM

NL
Topical
IM-PO
PO
PO
IM-PO
SC
IM
SC
PO-Topical
PO
SC
PO
ParenteralPO
IM-PO-SC
SC
SC
IM
SC
PO

ROUTE

PRN
PRN
PRN

PRN
PRN

PRN

PRN
PRN

BID-QID
TID

BID
BID
BID

q2-4w
NL
Once
NL
NL
QD

NL
NL
q10d
Once
QW
q2w
NL
Once
Once
QW
NL
NL
NL
NL

DOSAGE
INTERVAL

E
E
G

C
E

E
D

G
E

G
E
G

D
G
G
G
G
G

E
E
G
G
G
E
G
B
B
E
E
G
G
G

704
704
53

1392
243

1503

243
1403

632
1612

739
565
739

1446
57
234
1409
1308
1645

1559
1240
1309
932
861
629
1308
1427
1585
1438
1478
57
232
260

C.I.** REFERENCE

Add midazolam
Add medetomidine
Add midazolam

Add diazepam, higher dosage for smaller bird

Add xylazine
Add diazepam, supplement at 15 mg/kg
PRN
Add medetomidine + midazolam,
atipamezole + flumazenil reverses, good
anesthesia 30 minutes

Neonate dosage
For diarrhea

For large waterfowl

For microfilaria

For capillariasis

For air sac mites and scaly leg mites


Nematodes and mites
Effective against chandlerellosis
For serratospiculiasis
For capillariasis
For mites
For nematodes

For parasites
Injectable form may be toxic

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

20
5-10
10-25

5-25
10-30

10

0.4-0.8
0.2
0.4
0.3
0.2
0.2
0.2
2-3
1
0.2-0.4
0.4-1
0.3
0.2
0.5-1

Bird, Aquatic
Budgerigar
Budgerigar
Bustard, Houbara
Canary
Crane
Emu
Falcon
Falcon
Passerine
Penguin
Pigeon
Pigeon
Pigeon

Ivermectin
Ivermectin
Ivermectin
Ivermectin
Ivermectin
Ivermectin
Ivermectin
Ivermectin
Ivermectin
Ivermectin
Ivermectin
Ivermectin
Ivermectin
Ivermectin

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

284
C l i n i c a l Av i a n M e d i c i n e - Vo l u m e I

Avian
Bird, Aquatic
Bird, Aquatic
Canary
Cassowary
Chicken
Chicken

Cockatiel
Cockatoo, Palm
Duck, Mallard

Duck, Pekin
Emu
Emu
Falcon, Peregrine

Finch
Galliformes

Goose
Goose
Guinea Fowl
Hawk
Hawk

Hawk, Broad-winged
Heron
Ostrich

Ostrich
Owl
Pelican
Pigeon
Pigeon

Poultry
Poultry
Psittacine

Ketamine HCl
Ketamine HCl
Ketamine HCl
Ketamine HCl
Ketamine HCl
Ketamine HCl
Ketamine HCl

Ketamine HCl
Ketamine HCl
Ketamine HCl

Ketamine HCl
Ketamine HCl
Ketamine HCl
Ketamine HCl

Ketamine HCl
Ketamine HCl

Ketamine HCl
Ketamine HCl
Ketamine HCl
Ketamine HCl
Ketamine HCl

Ketamine HCl
Ketamine HCl
Ketamine HCl

Ketamine HCl
Ketamine HCl
Ketamine HCl
Ketamine HCl
Ketamine HCl

Ketamine HCl
Ketamine HCl
Ketamine HCl

50
30
3-7

2
10
7
20
5

30-40
20
5

5-10
20-50
25
25-30
4-5

100-200
3

20
3
2.2
30

25
5
8.8

10-50
3-8
2.5-5
100-200
2.2
20-100
4-5

DOSAGE (mg/kg
unless otherwise
stated)

IM
IM-SC
IM

IM
IM-SC
IM
IM
IM

IV
NL
IV

IM-IV
IM
IM
IM
Parenteral

IM
Parenteral

IV
NL
IV
IV

IM
IM-SC
IM

IM
IM
IV
IM
IV
IM
Parenteral

ROUTE

PRN
PRN
PRN

PRN
PRN
PRN
PRN
PRN

PRN
PRN
PRN

PRN
PRN
PRN
PRN
PRN

PRN
PRN

Once
PRN
PRN
PRN

PRN
PRN
PRN

PRN
PRN
PRN
PRN
PRN
PRN
PRN

DOSAGE
INTERVAL

E
E
B

B
E
G
B
B

B
G
B

B
G
B
E
G

G
G

B
C
E
D

E
E
B

G
E
E
G
E
G
G

4
924
1577

1628
924
595
779
1588

1092
1356
555

1577
1328
553
243
1718

1328
1718

718
1392
1533
1401

243
924
764

53
1503
1503
1328
1533
1328
1718

C.I.** REFERENCE

Sedative
Add medetomidine

Follow with propofol


Add medetomidine, usually moderate to
heavy sedation

Add medetomidine
Sedative

Add xylazine + alphaxalone/alphadolone

Add xylazine
Add xylazine
Add butorphanol + medetomidine,
preanesthetic for isoflurane, improves quality
of anesthesia
Combine with diazepam

Add butorphanol + medetomidine,


preanesthetic for isoflurane
Add medetomidine

Tranquilization
Add xylazine
Add diazepam, supplement at 5 mg/kg IV
PRN

Add butorphanol + medetomidine,


preanesthetic for isoflurane
Add xylazine
Sedative
Add medetomidine + midazolam, 33%
mortality

Add xylazine

Add diazepam
Add medetomidine
Add xylazine

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

SPECIES

DRUG NAME

Chapter 9 | T H E R A P E U T I C A G E N T S

285

12.5
10
30
12.5
10-30

Psittacine
Psittacine
Psittacine
Raptor
Raptor
Raptor
Ratite
Ratite
Ratite
Rhea
Spoonbill
Stork
Swan

Swan, Mute
Vulture

Amazon Parrot
Amazon, Yellow-naped
Avian

Avian
Bird, Aquatic

Canary
Canary
Ostrich
Passerine, Small
Passerine, Small
Pigeon
Pigeon
Pigeon

Ketamine HCl
Ketamine HCl
Ketamine HCl
Ketamine HCl
Ketamine HCl
Ketamine HCl
Ketamine HCl
Ketamine HCl
Ketamine HCl
Ketamine HCl
Ketamine HCl
Ketamine HCl
Ketamine HCl

Ketamine HCl
Ketamine HCl

Ketoconazole
Ketoconazole
Ketoconazole

Ketoconazole
Ketoconazole

Ketoconazole
Ketoconazole
Ketoconazole
Ketoconazole
Ketoconazole
Ketoconazole
Ketoconazole
Ketoconazole

Feed
Drink
PO
Drink
Feed
PO
PO
Gavage

PO
PO

PO
PO
PO

IV
IM

IM
IV
IM-SC
IM
IV
IM
IM
IV
NL
IM
NL
NL
IV

IV
NL

ROUTE

QD
QD
QD
NL
Once
BID
QD
QD

BID
BID

BID
BID
BID

PRN
PRN

PRN
PRN
PRN
PRN
PRN
PRN
PRN
PRN
PRN
PRN
PRN
PRN
PRN

PRN
PRN

DOSAGE
INTERVAL

D
E
G
E
E
A
E
E

D
E

B
G
D

E
B

E
E
E
B
B
B
E
E
E
G
G
G
G

B
D

1330
695
401
1187
1187
68
704
1240

1743
1503

68
740
1330

1190
568

649
649
924
1176
1577
1577
4
243
1386
1628
1356
1356
1291

1577
1401

C.I.** REFERENCE

Tables crushed and water suspension


For resistant candidiasis, Mucor and
Penicillium

Dissolve 50 mg tablet 0.2 ml HCl + 0.8 ml


water, mix with acid juice, lactulose,
methylcellulose
For systemic yeast
For candidiasis and aspergillosis therapy not
responding to nystatin

Add xylazine
Add xylazine

Add medetomidine, gas anesthesia premed

Add medetomidine
Add medetomidine
Sedative
For laparoscopy
Add medetomidine
Add medetomidine
Add medetomidine
Proceed with xylazine
May add diazepam or xylazine if desired
Add butorphanol + medetomidine

Add medetomidine
Add diazepam, supplement at 5 mg/kg PRN

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

0.2 g/kg soft food


0.2 g/L
10
1 g/L
0.2 g/kg food
30
3
3

10-30
25

3-7
2.5-7
20
25-35
2-4
3-5
3-7
2-4
3-20
6.6
20
20
4

2-5
10

Psittacine
Psittacine

Ketamine HCl
Ketamine HCl

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

286
C l i n i c a l Av i a n M e d i c i n e - Vo l u m e I

60
25
5-10
12.5

1
2
1-4
5
1 mg TD
2
2
0..07 g TD
0.3 ml/kg
200
75
90-120 g/ton
0.75-1
0.1

Psittacine

Raptor
Raptor

Raptor
Raptor
Ratite
Swan

Anseriformes
Avian
Avian
Duck

Pigeon
Psittacine
Quail

Amazon Parrot
Avian
Psittacine

Chicken
Galliformes

Amazon, Yellow-naped
Avian

Avian
Avian
Avian

Avian
Avian

Ketoconazole

Ketoconazole
Ketoconazole

Ketoconazole
Ketoconazole
Ketoconazole
Ketoconazole

Ketoprofen
Ketoprofen
Ketoprofen
Ketoprofen

Ketoprofen
Ketoprofen
Ketoprofen

Lactulose
Lactulose
Lactulose

Lasalocid
Lasalocid

Leuprolide Acetate
Leuprolide Acetate

Leuprolide Acetate
Leuprolide Acetate
Leuprolide Acetate

Leuprolide Acetate
Leuprolide Acetate

IM
IM

IM
Parenteral
IM

Parenteral
IM

Feed
Feed

PO
PO
PO

IM-SC
IM
PO

IM
IM
IM
IM

PO
PO
PO
PO

PO
IM

PO

PO

ROUTE

q2w
q2w

q2w
NL
NL

q2-3w
NL

QD
QD

BID-TID
NL
BID-TID

QD-BID
NL
NL

QD
NL
NL
NL

BID
BID
QD
BID

BID
BID

BID

BID

DOSAGE
INTERVAL

G
G

E
E
E

G
D

B
C

G
E
G

E
E
B

D
D
E
B

E
E
G
D

E
E

994
994

1151
1474
1570

1033
1475

958
705

1309
1492
632

1240
1240
1674

1150
1240, 1533
1167
1339

1240
1359
1309
1330

1132
1240

1240

763

C.I.** REFERENCE

Depot formulation
For feather picking triggering by excessive
behavior
After egg binding
Treat chronic egg laying
Use 30-day depot formulation for egg
chronic egg laying
For birds 300 g or less
For birds more than 300 g

For coccidial prophylaxis


For coccidial prophylaxis

For hepatic encephalopathy


For liver disease
Neonate dosage

Effective 30 to 70 minutes, given during


isoflurane anesthesia
Pain relief, arthritis, antiinflammatory
"

For pain relief or arthritis

Dissolve 50 mg tablet 0.2 ml HCl + 0.8 ml


water, mix with acid juice, lactulose,
methylcellulose

For resistant candidiasis, Mucor and


Penicillium
"

For resistant candidiasis, Mucor and


Penicillium

For candidiasis or adjunct for aspergillosis


therapy, disguise taste in food

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

0.75
0.5

0.5-1
0.1-0.14
0.052-0.156

15
25

10

25

Psittacine

Ketoconazole

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

Chapter 9 | T H E R A P E U T I C A G E N T S

287

25-50
2
2
10-20
8

Anseriformes
Avian
Avian
Avian
Avian

Avian
Avian
Avian

Avian
Crane

Crane

Finch

Galliformes
Galliformes
Magpie
Ostrich
Parakeet, Australian
Pheasant
Pigeon
Pigeon
Pigeon
Pigeon
Pigeon
Pigeon
Poultry
Poultry
Psittacine
Psittacine

Levamisole HCl
Levamisole HCl
Levamisole HCl
Levamisole HCl
Levamisole HCl

Levamisole HCl
Levamisole HCl
Levamisole HCl

Levamisole HCl
Levamisole HCl

Levamisole HCl

Levamisole HCl

Levamisole HCl
Levamisole HCl
Levamisole HCl
Levamisole HCl
Levamisole HCl
Levamisole HCl
Levamisole HCl
Levamisole HCl
Levamisole HCl
Levamisole HCl
Levamisole HCl
Levamisole HCl
Levamisole HCl
Levamisole HCl
Levamisole HCl
Levamisole HCl

PO
PO
SC
PO
Gavage
SC
IM
Drink
PO
PO
PO
PO
PO
PO-SC
IM
PO

PO

PO

PO
PO

PO-SC
IM-SC
Drink

SC
PO
IM-SC
PO
IM-SC

IM
IM
IM

ROUTE

Once
Once
NL
NL
q10d
NL
QD
QD
Once
Once
Once
Once
Once
NL
r2w
QD

NL

q2w

NL
q2w

q2w
q2w
QD

Once
QD
q2w
q2w
r10d

q2w
QD
q2-3w

DOSAGE
INTERVAL

E
E
G
B
G
G
E
E
E
E
G
G
G
E
E
E

E
E

E
E
E

D
D
E
E
E

G
D
E

1503
1526
1609
526
1309
678
704
704
1503
1526
232
260
1332
111
763
1240

1650

1361

1492
1361

1434
1473
1479

1150, 1190
1470
111
704
741

1278
1446
1359

C.I.** REFERENCE

Emesis common
Loft treatment for capillariasis and ascariasis,
follow up with parenteral therapy

Repeat in 2 weeks if needed

Add resorantel
For intestinal nematodes, use injectable
Histomoniasis therapy

For roundworms, cecal worms and hair


worms
For most worms
Chick dosage for intestinal strongyles, acarids
and capillarids
For intestinal strongyles, ascarids and
capillarids
For most worms except tapeworm,
particularly effective on acuaria in Australian
finch

Not for debilitated birds or lories, use


13.65% injectable

Control nematodes
For liver parasitic disease

Induce molt
For sexually-triggered feather picking
For cystic ovaries

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

40
40
30
30
15
25
15
0.18 g/L
40
40
10-20
40
18-36
1.25-2.5
20
20-50

40-50

40

40-50
25

10-20
5
0.8 g/L

0.75
0.1
0.25

Avian
Psittacine
Raptor

Leuprolide Acetate
Leuprolide Acetate
Leuprolide Acetate

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

288
C l i n i c a l Av i a n M e d i c i n e - Vo l u m e I

30
20 ug/kg
1
20-100 ug/kg
20 ug/kg
0.0008-0.0025 g/L
0.02-0.04
0.02
0.004-0.008 g/L
0.003 g/L
0.020-0.1
1
2-3
2
10

75
50
0.2 g/L
100
50
25-50
35-50
2.2 mg/kg food
0.017 g/L

Ratite

Avian
Avian
Avian
Avian
Avian
Avian
Avian
Budgerigar
Budgerigar

Psittacine
Raptor

Avian
Raptor

Raptor

Amazon Parrot
Avian
Avian
Avian
Hawk
Pigeon
Pigeon
Poultry
Poultry

Levamisole HCl

Levothyroxine Sodium
Levothyroxine Sodium
Levothyroxine Sodium
Levothyroxine Sodium
Levothyroxine Sodium
Levothyroxine Sodium
Levothyroxine Sodium
Levothyroxine Sodium
Levothyroxine Sodium

Levothyroxine Sodium
Levothyroxine Sodium

Lidocaine
Lidocaine

Lidocaine

Lincomycin HCl
Lincomycin HCl
Lincomycin HCl
Lincomycin HCl
Lincomycin HCl
Lincomycin HCl
Lincomycin HCl
Lincomycin HCl
Lincomycin HCl

PO
PO
Drink
IM
PO
IM
PO
Feed
Drink

SC

SC
SC

PO
PO

PO
IM-PO
PO
PO
Drink
PO
PO
Drink
Drink

IM-PO

IM-SC
SC
SC
PO-SC
PO-SC
SC
IM-PO

ROUTE

BID
BID
QD
BID
BID
NL
QD
QD
QD

NL

NL
NL

BID
QD

QD-BID
NL
BID
QD-BID
QD
QD
QD-BID
QD
QD

q3m

q10d
NL
NL
QD
NL
q4-6d
QM

DOSAGE
INTERVAL

E
E
E
E
G
G
G
C
C

B
E

E
E

E
E
E
E
E
G
G
D
G

E
G
G
E
E
D
G

111, 1431
1234
1431
1431
1110
260
590
564
564

1463

1346
1400

1240
1160

111
924
1431
1473
1492
58
88
1446
1309

1308

1240
678
678
1400
1463
1612
1308

C.I.** REFERENCE

For bumblefoot
For infected foot lesions
For infected foot lesions
Therapy prior to tendon surgical repair

Local infiltration
Dilute to 0.4%, infuse locally, use with
caution in small birds
Dilute to 0.2% for large bird local analgesia

For lipomatous growth and xanthomas


For hypothyroidism, stir water and offer for
15 minutes, repeat daily
For hypothyroidism
To induce molting

For goiter and hypothyroidism

For severe feather disorders and lipomas


Monitor levels to avoid thyrotoxicosis

Immunostimulant, low therapeutic index


Histomoniasis therapy
Anthelmintic
Narrow therapeutic margin
Anthelmintic
Immune stimulant
Begin at 1 month of age, juvenile dose for
Libyastrongylus douglassi
Adult dose for Libyastrongylus douglassi

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

2-5
25
20
10-20
15
2
30

Psittacine
Quail
Quail
Raptor
Raptor
Raptor
Ratite

Levamisole HCl
Levamisole HCl
Levamisole HCl
Levamisole HCl
Levamisole HCl
Levamisole HCl
Levamisole HCl

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

Chapter 9 | T H E R A P E U T I C A G E N T S

289

110
50
50
30
50

6-25

0.01-50
7.5
5
500-1000

Raptor

Avian

Chicken

Falcon

Pigeon

Avian

Poultry

Avian
Chicken

Anseriformes

Bird, Aquatic
Budgerigar

Canary
Chicken
Crow, Eastern
Eagle, Golden
Gull (Herring, laughing)
Hawk, Marsh
Ostrich
Pigeon

Raptor

Lincomycin HCl

Lincomycin HCl +
Spectinomycin HCl
Lincomycin HCl +
Spectinomycin HCl
Lincomycin HCl +
Spectinomycin HCl
Lincomycin HCl +
Spectinomycin HCl

Lithium Carbonate

LL-E19020

Maduramicin
Maduramicin

Magnesium Sulfate

Magnesium Sulfate
Magnesium Sulfate

Magnesium Sulfate
Magnesium Sulfate
Magnesium Sulfate
Magnesium Sulfate
Magnesium Sulfate
Magnesium Sulfate
Magnesium Sulfate
Magnesium Sulfate

Magnesium Sulfate

PO

IM
IM
IM
IM
IM
IM
PO
IM

PO
IM

PO

PO
Feed

Feed

NL

PO

IM

PO

PO

PO

IM

ROUTE

QD

PRN
PRN
PRN
PRN
PRN
PRN
NL
PRN

NL
PRN

QD

QD
QD

QD

BID

QD

TID

QD

QD

QD

BID

DOSAGE
INTERVAL

B
B
B
B
B
B
G
B

E
B

E
B

1400

1084
1084
1084
1086
1084
1086
401
1084

1503
1084

1240

1650
958

564

1477

1061

1027

1065

565

741

1240

C.I.** REFERENCE

For oral heavy metal poisoning

Add chloral hydrate + pentobarbital sodium,


reduce dose 15 to 20% in debilitated birds

See above
See above
See above
See above
See above
See above

Precipitates lead and cathartic


Add chloral hydrate + pentobarbital sodium,
reduce dose 15 to 20% in debilitated birds

Increase gut motility and aid passage of lead

For Plasmodium
For coccidial prophylaxis

Improves feed efficiency

For avian behavior problems, mood stabilizer


and antipsychotic, no longer used in birds

Broad spectrum for mycoplasma and


salmonella

For skin disease

For Gram positive bumblefoot, dermatitis


and mycoplasmal respiratory infection.

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

250-1000

53
53
53
40.3
53
32.4
1.25-30 ml TD
53

500-1000
53

100

Psittacine

Lincomycin HCl

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

290
C l i n i c a l Av i a n M e d i c i n e - Vo l u m e I

1 g/L

5% mixture
0.5
2
10
2
10
15-20
5-15
25
10
0.06 g/kg food
5-6
25
25
2.2
2.2
2.2
2.2
2

Avian

Avian

Raptor

Avian

Buzzard, Common
Buzzard, Common
Chicken
Raptor
Raptor

Anseriformes
Avian
Canary
Fowl, Domestic
Pigeon
Psittacine
Raptor

Avian
Avian
Avian
Bird, Aquatic

Amazon, Yellow-crowned

Anseriformes
Anseriformes
Anseriformes

Avian
Bird, Aquatic
Bird, Aquatic

Malathion

Malathion

Malathion

Mannitol

Marbofloxacin
Marbofloxacin
Marbofloxacin
Marbofloxacin
Marbofloxacin

Mebendazole
Mebendazole
Mebendazole
Mebendazole
Mebendazole
Mebendazole
Mebendazole

Meclofenamic Acid
Meclofenamic Acid
Meclofenamic Acid
Meclofenamic Acid

Medetomidine HCl

Medetomidine HCl
Medetomidine HCl
Medetomidine HCl

Medetomidine HCl
Medetomidine HCl
Medetomidine HCl

IM
IV
IM

IV
IM
Parenteral

IM

PO
PO
PO
PO

PO
PO
PO
Feed
PO
PO
PO

IV
PO
PO
IM-PO
IM-PO

IV

Topical

Dip

Topical

PO

ROUTE

NL
PRN
PRN

PRN
PRN
PRN

PRN

QD
QD
QD
QD

QD
QD
BID
QD
QD
BID
BID

BID
QD
QD
QD
QD

QD

q10d

NL

NL

QD

DOSAGE
INTERVAL

G
E
E

D
E
G

D
G
E
E

D
E
G
E
G
E
E

A
A
A
E
G

704, 1320
1503
1503

1503
1231
1718

1629

1533
201, 1320
1573
1503

1,150,111
1492, 1650
57
1051
260
111, 1473
111

778, 1428
979
765
1433
1068

111

1411

1479

1479

1240

C.I.** REFERENCE

Add ketamine, reverse with atipamezole


Add ketamine, reverse with atipamezole

Sedation produced not reliable, reverse with


atipamezole
Add ketamine + midazolam
Add ketamine
Add butorphanol + ketamine, preanesthetic
for isoflurane

Control Syngamus
For all intestinal worms
Avoid during breeding season

For sinusitis

Give slowly

Remove birds and treat environment for flea,


lice, mange and mite treatment and aid in tick
control
For flea, lice, mange and mite treatment and
aid in tick control
For chewing lice

Increase gut motility and aid passage of lead

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

0.1
0.025-0.075
0.05-0.1

0.05
0.6-0.85
0.06

1 g/L

500-1000

Raptor

Magnesium Sulfate

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

Chapter 9 | T H E R A P E U T I C A G E N T S

291

Pigeon
Psittacine
Psittacine
Psittacine
Raptor

Raptor
Raptor
Raptor
Raptor
Ratite
Rhea
Swan

Medetomidine HCl
Medetomidine HCl
Medetomidine HCl
Medetomidine HCl
Medetomidine HCl

Medetomidine HCl
Medetomidine HCl
Medetomidine HCl
Medetomidine HCl
Medetomidine HCl
Medetomidine HCl
Medetomidine HCl

0.025-0.075
0.05-0.1
0.15-0.35
0.2
0.05-0.15
0.73
0.15

0.2
0.075-0.15
0.05-0.1
0.06-0.085
0.1-0.3

0.1-0.2
0.06-0.08
0.08
0.1
0..08

IV
IM
IM
NL
IM
IM
IV

IM
IM
IV
IM
IM

IM-IV
Parenteral
IM
IM
IM

IM

PRN
PRN
PRN
PRN
PRN
PRN
PRN

PRN
PRN
PRN
PRN
NL

PRN
PRN
PRN
PRN
PRN

PRN

PRN
PRN
PRN

B
B
E
E
E
G
G

B
B
B
E
E

B
G
B
E
B

B
E
G

1577
1577
1240
1433
4
1628
1291

1588
1577
1577
1240
1400

1577
1718
1628
1573
1588

764

1229
1573
1718

C.I.** REFERENCE

Add ketamine
Add butorphanol + ketamine
Add ketamine
Sedation
Add ketamine, usually moderate to heavy
sedation
Variable light sedation
Add ketamine
Add ketamine
Add ketamine
Can be reversed, combined with ketamine for
anesthesia
Add ketamine
Add ketamine
Add ketamine
Add ketamine, reverse with atipamezole
Add ketamine
Add butorphanol + ketamine
Add ketamine, gas anesthesia premed

For restraint of captive birds


Sedation
Add butorphanol + ketamine, preanesthetic
for isoflurane
Add ketamine + midazolam, 33% mortality

COMMENTS (see references for


duration, precautions and
contraindications)

40
50
30
5-25

Avian

Avian

Avian

Avian

IM-SC

IM-SC

IM-SC

IM-SC

IM-SC

QD

QD

QD

QD

QD

111

111

111

111

111

For 300 to 700 g bird

For <150 g bird

For 150 to 300 g bird

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

25

Avian

For 700 g bird

Goose
Hawk
Ostrich
Ostrich
Pigeon

Medetomidine HCl
Medetomidine HCl
Medetomidine HCl
Medetomidine HCl
Medetomidine HCl

0.44

IM
IM
Parenteral

DOSAGE
INTERVAL

Medroxyprogesterone
Acetate
Medroxyprogesterone
Acetate
Medroxyprogesterone
Acetate
Medroxyprogesterone
Acetate
Medroxyprogesterone
Acetate

Duck, Mallard

Medetomidine HCl

0.26-0.31
0.1
0.06-0.08

ROUTE

Lower dose for larger birds. Side effects:


lethargy, inappetance, polydipsia, fatty liver

Cassowary, Double-wattled
Chicken
Chicken

Medetomidine HCl
Medetomidine HCl
Medetomidine HCl

DOSAGE (mg/kg
unless otherwise
stated)

Medroxyprogesterone
Acetate

SPECIES

DRUG NAME

292
C l i n i c a l Av i a n M e d i c i n e - Vo l u m e I

2-10
25-50

30

2.5
0.2 g/L
0.2 g/kg food
0.1
0.1-0.2
0.1 - 1.0
0.1
0.1
0.1
0.5
0.1-0.2
0.1
3-5
3-5
100 mg/L water

50
5-10
5 g/L bait
5-10
5-10
4-8

Avian

Psittacine

Passerine

Avian

Cockatoo, Rose-breasted
Cockatoo, Rose-breasted

Avian
Avian
Avian
Avian
Avian
Avian
Crane
Raptor

Raptor

Raptor
Raptor

Avian

Avian

Chicken
Dove
Duck
Goose
Poultry

Mefloquine HCl

Megestrol Acetate

Megestrol Acetate
Megestrol Acetate

Meloxicam
Meloxicam
Meloxicam
Meloxicam
Meloxicam
Meloxicam
Meloxicam
Meloxicam

Meloxicam

Meperidine HCl
Meperidine HCl

Metformin (glucophage)

Methocarbamol

Methohexital Sodium
Methohexital Sodium
Methohexital Sodium
Methohexital Sodium
Methohexital Sodium

IV
Feed
IV
IV
IV

IV

Drink

NL
NL

IM-PO

IM-PO
IM
PO
NL
PO
PO
PO
IM-PO

Drink
Feed

NL

PO

IM-SC

PO-SC

IM-SC

ROUTE

PRN
Once
PRN
PRN
PRN

NL

QD

QID
NL

QD

QD
QD
QD
QD
QD
QD
BID
QD

NL
Once

QD

PRN

q4-6w

QW

NL

DOSAGE
INTERVAL

G
G
G
G
G

G
G

E
E
G
G
G
E
G
E

G
G

For arthritis and other painful conditions

Long course well tolerated

Long course well tolerated

Then continue q3-4d for feather picking with


hormonal etiology
For self-mutilation
For self-mutilation

Give BID on day 1, give daily on days 2 and


3 and once per week

Repeat after 4 months for ovulation


suppression
Lower dose for larger birds. Side effects:
lethargy, inappetance, polydipsia, fatty liver

For persistent egg laying

COMMENTS (see references for


duration, precautions and
contraindications)

497
1763
498
498
496

201

Corn is usual bait

T. Lightfoot, 2005 Hyperglycemia

1481
1483, 1484

1359, 1433

1167, 1431
1431
1341
1484
1671, 1675
1431
1341
1400

1609
1609

1431

1438

1240

924

704

C.I.** REFERENCE

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

5-10

Avian

Medroxyprogesterone
Acetate
Medroxyprogesterone
Acetate
Medroxyprogesterone
Acetate

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

Chapter 9 | T H E R A P E U T I C A G E N T S

293

0.3
0.5

0.5
0.5
0.5-2
10
17
15.2
9.6
14.4-16
15-20

Avian
Avian

Avian
Avian
Hawk, Red-tailed
Lorikeet, Rainbow
Macaw
Ostrich

Psittacine
Psittacine
Raptor

Avian
Duck, Mallard
Eagle, African Hawk
Eagle, Tawny
Hawk, African Harrier
Ostrich

Owl, Barn
Raptor
Raptor
Turkey

Metoclopramide HCl
Metoclopramide HCl

Metoclopramide HCl
Metoclopramide HCl
Metoclopramide HCl
Metoclopramide HCl
Metoclopramide HCl
Metoclopramide HCl

Metoclopramide HCl
Metoclopramide HCl
Metoclopramide HCl

Metomidate HCl
Metomidate HCl
Metomidate HCl
Metomidate HCl
Metomidate HCl
Metomidate HCl

Metomidate HCl
Metomidate HCl
Metomidate HCl
Metomidate HCl

IM
IM
IM
Feed

IM
PO
IM
IM
IM
IM

IM-IV-PO
NL
IM-SC

IM-IV-PO
Parenteral
IM
SC
IM-PO
IV

IM-IV-PO
IM

IM-IV

PRN
PRN
PRN
Once

PRN
PRN
PRN
PRN
PRN
PRN

TID
BID
q4-6h

NL
NL
NL
BID
NL
NL

NL
BID-TID

NL

QW

NL

NL

NL

DOSAGE
INTERVAL

G
E
E
E

E
B
G
G
G
G

E
G
E

E
E
G
G
E
G

E
E

1611
1463
1463
1386

1130
1095
1611
1611
1611
481

1240
1263
1359

1473
1650
1626
1620
1151
1255

111
1151

1554

1463

1503

1533

1068

C.I.** REFERENCE

Smaller dosages for vultures


For sedation
Safer than chloralose

With or without azaperone for captive animal

Antiemetic and for gut stasis


For ileus
For gastrointestinal stasis

Increase gastric motility


Supportive therapy post-trauma
For vomiting
To improve motility- Use low dose
Add psyllium for proventricular obstruction

To improve motility, this dosage not for


macaws

For shock

Add permethrin + piperonyl butoxide for


ectoparasites

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

10.2
10
5
17 g/L whole corn

0.5
0.5
0.5
0.5
0.1
0.1

0.5-1

Avian

Methylprednisolone Acetate Raptor

Methylprednisolone
Sodium Succinate

IA-IM

0.5-1
IM

IA-IM

Topical

0.5-1

0.02 g/L

Raptor

Methoprene

ROUTE

Methylprednisolone
Avian
Acetate
Methylprednisolone Acetate Bird, Aquatic

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

294
C l i n i c a l Av i a n M e d i c i n e - Vo l u m e I

25
25-50
0.2 g/L
50
5
10-30
10
50
20
10-30
10
0.1 g/kg food
30
50
1.25 g/L
0.1 g/L
0.1 g/kg soft food
200
200-250
20
110
10-30
25
30-50
50
100
50
10-40
100
30-65
20-25
42
2 mg
20
10-20
20

Avian
Avian
Avian
Avian
Avian
Avian
Avian
Avian
Avian
Avian
Avian
Canary
Chicken
Falcon
Ostrich
Passerine
Passerine
Pigeon
Pigeon
Poultry
Poultry
Psittacine
Psittacine
Raptor

Raptor
Raptor
Raptor
Raptor
Raptor
Raptor
Ratite
Stork, Saddle-billed

Amazon, Red Lored


Avian
Avian
Avian

Metronidazole
Metronidazole
Metronidazole
Metronidazole
Metronidazole
Metronidazole
Metronidazole
Metronidazole
Metronidazole
Metronidazole
Metronidazole
Metronidazole
Metronidazole
Metronidazole
Metronidazole
Metronidazole
Metronidazole
Metronidazole
Metronidazole
Metronidazole
Metronidazole
Metronidazole
Metronidazole
Metronidazole

Metronidazole
Metronidazole
Metronidazole
Metronidazole
Metronidazole
Metronidazole
Metronidazole
Metronidazole

Miconazole Nitrate
Miconazole Nitrate
Miconazole Nitrate
Miconazole Nitrate

Nebulize
IV
IM
IM

PO
PO
PO
PO
PO
PO
PO
PO

PO
PO
Drink
PO
IM
PO
IM
PO
PO-SC
PO
IM
Feed
PO
PO
Drink
Drink
Feed
PO
PO
Drink
PO
PO
PO
PO

ROUTE

QD
TID
QD
NL

QD
NL
QD
QD
QD
QD
BID
BID

BID
QD
NL
NL
BID
BID
QD
QD
QD
BID
QD
Once
BID
QD
QD
QD
QD
QD
QD
QD
BID
BID
BID
QD

DOSAGE
INTERVAL

G
D
E
E

E
E
G
G
G
G
G
G

D
E
E
E
E
E
E
G
C
D
D
E
A
E
E
E
E
E
G
C
G
E
E
E

700
1330
565
924

1400, 1433
1463
61, 234
94
1068
1409
1308
1645

1221
704, 924
1180
1434
1434
1650
1650
55
705
1470
1470
1187
795
1027
627
1437
1437
704
260
705
585
111, 1473
763
1359

C.I.** REFERENCE

For candidiasis, Aspergillus, Mucor and


Penicillium

Add acetylcysteine

For trichomoniasis
For anaerobic infections
Add amikacin + enrofloxacin

Juvenile dosage

For trichomoniasis, may increase dosage to


100 mg/kg
For trichomoniasis
For trichomoniasis

For trichomoniasis
Antihistomoniasis
Add drug to food at the same time
Add drug to drink at the same time

For trichomoniasis
For liver parasitic disease
For liver parasitic disease

For anaerobic infections


For anaerobic infections

For clostridiosis

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

Chapter 9 | T H E R A P E U T I C A G E N T S

295

cream
20
10
2
1-2
1-2
1
1-2
4
0.2

0.1-1
2
2
2 drops mixture TD

5 ml/kg
5.5 g/kg seed

Falcon
Psittacine
Raptor

Anseriformes
Anseriformes
Avian
Avian
Avian
Avian
Avian

Duck, Mallard
Emu
Ostrich
Pheasant, Ring-necked
Pigeon

Pigeon

Psittacine
Raptor
Swan

Turkey

Galliformes
Galliformes

Amazon Parrot

Avian

Budgerigar

Miconazole Nitrate
Miconazole Nitrate
Miconazole Nitrate

Midazolam HCl
Midazolam HCl
Midazolam HCl
Midazolam HCl
Midazolam HCl
Midazolam HCl
Midazolam HCl

Midazolam HCl
Midazolam HCl
Midazolam HCl
Midazolam HCl
Midazolam HCl

Midazolam HCl

Midazolam HCl
Midazolam HCl
Midazolam HCl

Midazolam HCl

Milbemycin Oxime
Milbemycin Oxime

Milk Thistle

Mineral Oil

Minocycline HCl

Feed

Gavage

PO

PO
PO

NL

IM-SC
IM-IV
NL

IM

IM
IV
IV
IM
IM

IV
IV
IM-IV
IM
IM-IV
IM
IM

Topical
IM-IV
IM-IV

IV

ROUTE

QD

Once

BID

QM
NL

PRN

PRN
TID
PRN

PRN

Once
PRN
PRN
PRN
PRN

PRN
PRN
NL
NL
NL
PRN
PRN

BID
QD
QD

NL

DOSAGE
INTERVAL

B
E

E
E
G

G
G
G
G
B

D
E
E
G
G
E
E

G
E
E

731

1309, 1554

1488

588
1492, 1650

1291

1240
1240, 1400
1291

1644

1468
418
418
1644
1588

1503, 1533
1503
1573
201
1320
704
1181, 1231

1589
704
704

924

C.I.** REFERENCE

Hulled medicated millet,

To flush GI - laxative

Mixture is 5 drops extract per 7.5 ml


lactulose, useful for treating birds on all seed
diet

For Heterakis, Capillaria and ascarids

"

Anesthesia premed
Add medetomidine, usually moderate to
heavy sedation
Add glycopyrrolate for anesthesia premed,
reverse with flumazenil
Use in combination with ketamine
Control seizures
May add butorphanol, premed for gas
anesthesia, lower dosage if add butorphanol

Use with an analgesic for pain control


Add ketamine
Add ketamine, smooth induction and
recovery
Pre-gas anesthesia

Add ketamine + medetomidine


"
"

For candidiasis, Aspergillus, Mucor and


Penicillium

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

0.2
0.5-1
0.1-1

4
0.4
0.15
1
0.5

40

Avian

Miconazole Nitrate

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

296
C l i n i c a l Av i a n M e d i c i n e - Vo l u m e I

0.1 g/kg
0.1 g/kg
100
100-120 g/ton
0.099 g/kg food
0.099 g/kg food
1-1.2 g/kg feed
1-1.2 g/kg food
90-100 g/ton
2.5-3
0.2-0.8
0.2
1
2
0.2
0.25 mg TD
0.2
0.2
0.2
10 drops/kg
0.05 ml TD

1-2
0.05-0.25
0.05-0.25
0.05-0.067
1.5
300 mg TD

Poultry

Chicken
Chicken
Chicken
Crane
Galliformes
Pigeon
Pigeon
Turkey

Galliformes

Avian
Cardinal, Red-crested
Falcon

Finch
Penguin
Pigeon
Psittacine
Raptor
Sparrowhawk

Avian

Crane, Whooping

Guinea Fowl

Avian
Psittacine
Ratite

Avian
Ostrich

Miporamicin

Monensin Sodium
Monensin Sodium
Monensin Sodium
Monensin Sodium
Monensin Sodium
Monensin Sodium
Monensin Sodium
Monensin Sodium

Morphine Sulfate

Moxidectin
Moxidectin
Moxidectin

Moxidectin
Moxidectin
Moxidectin
Moxidectin
Moxidectin
Moxidectin

Mullein

Mycobacterium Vaccae
Vaccine

Nalbuphine HCl

Naloxone HCl
Naloxone HCl
Naloxone HCl

Naltrexone HCl
Naltrexone HCl

Drink
IV

IM-IV
IM-IV
NL

IM

ID

PO

PO
PO
PO
Gavage
PO
SC

NL
PO
PO

IM-SC

Feed
Feed
Feed
Feed
Feed
Feed
Feed
Feed

Feed

PO

ROUTE

NL
PRN

PRN
NL
PRN

q3h

q2m

TID

NL
NL
NL
Once
QD
NL

Once
NL
QW

NL

QD
QD
QD
Once
QD
Once
QD
QD

QD

BID

DOSAGE
INTERVAL

E
B

E
G
G

E
E
D
D
E
G

D
G
G

B
B
C
E
E
E
E
C

704
521

1573
1320
418

252

207

1205

1479
1478
1479
1479
1359
1585

1221
1585
1068

111, 1473

869
958
705
111
1473
1492
1650
705

564

1179

C.I.** REFERENCE

Behavior modification, feather picking


Reverse carfentanil

Use slow IV

Respiratory, wound support

For capillariasis
For capillariasis
For Serratospiculum , Capillaria , Physlaoptera and
Acanthocephalae
For lice, mites and nematodes
For nematodes
For lice, mites and nematodes
For lice, mites and nematodes
For capillariasis
For nematodiasis

For coccidiosis
For coccidia
For coccidiosis

Preventive for coccidiosis


For coccidial prophylaxis
For coccidiosis

Add levamisole + Staphylococcus toxoid for


bumblefoot

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

Hawk, Red-shouldered

Minocycline HCl

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

Chapter 9 | T H E R A P E U T I C A G E N T S

297

0.4
0.4
70
60-80 mg/kg food

1.25 g/L
10
20
11
.077-.154 g/kg food
.077-.154 g/kg food
11
0.2 g/kg soft food
0.2 g/L
0.035-0.08 g/L
38.5-154 mg/kg food
11
15
0.035-0.08 g/L
0.35 g/L
20
20-50 mg/kg food

50
150-250
5 g/kg food
250
200
500
100
50
103-160

Psittacine

Raptor

Chicken
Chicken

Avian
Avian
Avian
Chicken
Chicken
Duck
Duck
Passerine
Passerine
Poultry
Poultry
Poultry
Raptor

Avian
Bird, Aquatic
Raptor

Chicken

Avian
Avian
Avian
Crane
Falcon
Finch
Ostrich
Ostrich
Pelican, Brown

Nandrolone

Nandrolone

Narasin
Narasin

Neomycin Sulfate
Neomycin Sulfate
Neomycin Sulfate
Neomycin Sulfate
Neomycin Sulfate
Neomycin Sulfate
Neomycin Sulfate
Neomycin Sulfate
Neomycin Sulfate
Neomycin Sulfate
Neomycin Sulfate
Neomycin Sulfate
Neomycin Sulfate

Netobimin
Netobimin
Netobimin

Nicarbazin

Niclosamide
Niclosamide
Niclosamide
Niclosamide
Niclosamide
Niclosamide
Niclosamide
Niclosamide
Niclosamide

PO
PO
Feed
NL
PO
Feed
PO
PO
PO

Feed

Drink
Drink
PO

Drink
PO
PO
Drink
Feed
Feed
Drink
Feed
Drink
Drink
Feed
PO
PO

Feed
Feed

IM-SC

IM-SC

PO

ROUTE

q2w
NL
QD
q2w
Once
QW
q6w
NL
Once

QD

QD
QD
QD

NL
QD
NL
BID
QD
QD
BID
QD
QD
QD
QD
QD
NL

QD
QD

q3w

q3w

BID

DOSAGE
INTERVAL

E
G
G
G
E
E
G
G
B

E
E
B

E
E
E
C
C
C
G
E
E
C
C
C
E

B
E

111
57
57
596
1027
111
401
481
1089

564

1492
1503
1568

111
565
924
1307
1307
1307
1307
1437
1437
564
564
564
1463

958
564

1240

1240

1240

C.I.** REFERENCE

For tapeworms

Add narasin, 5-day slaughter withdrawal,


prophylactic

For tapeworms, ascarids and Heterakis

For bacterial infections

Gram negative, poor absorption


For bacterial enteritis
For bacterial enteritis
For bacterial enteritis
For bacterial enteritis
Add drug to drink at the same time
Add drug to food at the same time
Prophylactic

For coccidial prophylaxis


Add nicarbazin, 5-day slaughter withdrawal,
prophylactic

For chronic and debilitating disease, may


cause liver disease
"

Prevent self-mutilation

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

1.5

Psittacine

Naltrexone HCl

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

298
C l i n i c a l Av i a n M e d i c i n e - Vo l u m e I

77 mg/kg food
75 mg/kg food
50 g/ton
40
1.25 ml/L
55 mg/kg food
0.625 cc/L
55 mg/kg food
1.25 cc/L
250 mg/kg food

24
2 drops/kg

10
8
20-40
10
30
8
10
10
0.016 g/L
5-10 mg/kg

385 mg/kg food

Poultry
Turkey

Turkey

Raptor

Avian
Chicken
Lorikeet
Poultry
Psittacine

Chicken

Galliformes

Avian

Chicken
Chicken
Chicken
Goose
Ostrich
Poultry
Turkey
Turkey

Psittacine

Chicken

Anseriformes

Nifursol
Nifursol

Nifursol

Nithiamide

Nitrofurazone
Nitrofurazone
Nitrofurazone
Nitrofurazone
Nitrofurazone

Nitromide

Nitroxinil

Nordihydroquaiaretic

Norfloxacin
Norfloxacin
Norfloxacin
Norfloxacin
Norfloxacin
Norfloxacin
Norfloxacin
Norfloxacin

Nortriptyline HCl

Nosiheptide

Novobiocin Sodium

Feed

Feed

Drink

PO
PO
Drink
PO
Drink
PO
PO
SC

PO

Drink

Feed

Drink
Feed
Drink
Feed
Drink

PO

Feed

Feed
Feed

PO
PO
PO

ROUTE

Once

QD

NL

BID
QD
NL
BID
QD
QD
QID
QD

BID

QD

QD

QD
QD
NL
QD
NL

NL

QD

QD
QD

NL
Once
NL

DOSAGE
INTERVAL

A
A
A
A
G
G
A
A

E
E
E
C
E

C
E

G
D
E

597

564

111

789
830
840
789
562
564
789
1020

1205

706

564

741
564
111
564
111

1463

705

564
564

57
1612
1068

C.I.** REFERENCE

Improves feed efficiency

Control feather picking

For Hemophilus paragallinarum infection.

Use with caution in egg layers or w/ hepatic


disease

For gapeworms

Add sulfanitran + roxarsone, 5-day slaughter


withdrawal

Dosage based on 9.2% powder

For coccidial infections


5-day slaughter withdrawal, prophylactic
Dosage based on 9.2% powder

For trichomoniasis

For histomoniasis

Prophylactic
Nutritional use, 5-day slaughter withdrawal

For cestodiasis
For cestodes

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

75
156
125

Pigeon
Raptor
Raptor

Niclosamide
Niclosamide
Niclosamide

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

Chapter 9 | T H E R A P E U T I C A G E N T S

299

300 KIU/kg
200 KIU/kg
0.05 g/kg food
300 KIU/kg
200-300 KIU/kg
100 KIU/L
333 KIU/kg
100 KIU/ml
25 KIU/L Nectar
2500 KIU/kg food
12.5 KIU/kg
0.24 g/kg feed
20-50 KIU/kg
100 KIU/L
20-100 KIU
100-150 KIU/kg
110 mg/kg food
300 KIU/kg
333 KIU/kg

Anseriformes
Avian
Avian
Avian
Avian
Avian
Finch
Hummingbird
Hummingbird
Ostrich
Ostrich
Ostrich
Ostrich
Passerine
Pigeon
Pigeon
Poultry
Psittacine
Psittacine

Raptor
Raptor
Raptor
Ratite
Ratite
Turkey

Nystatin
Nystatin
Nystatin
Nystatin
Nystatin
Nystatin
Nystatin
Nystatin
Nystatin
Nystatin
Nystatin
Nystatin
Nystatin
Nystatin
Nystatin
Nystatin
Nystatin
Nystatin
Nystatin

Nystatin
Nystatin
Nystatin
Nystatin
Nystatin
Nystatin

0.58 mg/kcal
25
50
0.2 g/kg food

Avian
Pigeon
Pigeon

Chicken

Oleandomycin Phosphate
Oleandomycin Phosphate
Oleandomycin Phosphate

Ormetoprim +
Sulfadimethoxine

Feed

IM
IM
PO

PO

PO
PO
PO
PO
PO
Feed

PO
Feed
PO
PO
PO
Drink
PO
Topical
Drink
Feed
PO
Feed
PO
Drink
PO
PO
Feed
PO-Topical
PO

Feed

ROUTE

QD

QD
QD
QD

QD

TID
BID
BID
NL
TID
QD

BID
QD
NL
BID
BID
QD
QD
q4-6h
QD
Once
QD
QD
QD
QD
QD
BID
QD
BID-TID
TID

Once

DOSAGE
INTERVAL

E
E
E

D
E
E
G
G
C

D
E
E
E
G
G
E
G
G
G
G
G
G
D
E
G
C
D
E

564

1180
565
565

1180

1612
1132
1188
418
594
1307

1150
704
924
1221
1373
1744
1572
599
599
283
401
1254
1254
1330
704
590
564
1330
763

984

C.I.** REFERENCE

5-day slaughter withdrawal, prophylactic

Half dosage is prophylactic


Upper GI candidiasis
For candidiasis, use lesser dosage to diet for
neonates on antibiotic therapy

Add to food also, upper GI Candidiasis

For candidiasis

For candidiasis
Soft food
For candidiasis
For candidiasis
For candidiasis
For candidiasis
For candidiasis
For mouth lesions

Prophylaxis for Pasteurella multocida in


ducklings.

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

1.17 mg/kcal

Oleandomycin Phosphate Avian

100 KIU/kg
1 KIU/kg
20 KIU/kg
300 KIU/kg
100 KIU TD
0.055-0.11 g/kg food

0.3 g/kg food

Duck, Pekin

Novobiocin Sodium

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

300
C l i n i c a l Av i a n M e d i c i n e - Vo l u m e I

0.22 g/kg
0.2-0.8 g/kg food
0.3-0.5 g/L
0.44 g/kg
0.1 g/kg food

100
10
40
4

10-40
10
22-58
2.5 g/L
50 mg TD
5000 mg/kg
50-100
50
100
100
2 g/L
2.5 g/L
10
16

Duck

Duck

Poultry

Turkey

Turkey

Psittacine

Avian
Avian
Avian

Avian

Avian
Avian
Ostrich

Pigeon
Raptor

Amazon Parrot
Anseriformes
Anseriformes
Avian
Avian
Avian
Avian
Bird, Aquatic
Budgerigar
Chicken
Ostrich
Owl

Oxacillin Sodium

Oxfendazole
Oxfendazole
Oxfendazole

Oxfendazole

Oxfendazole
Oxfendazole
Oxfendazole

Oxfendazole
Oxfendazole

Oxytetracycline
Oxytetracycline
Oxytetracycline
Oxytetracycline
Oxytetracycline
Oxytetracycline
Oxytetracycline
Oxytetracycline
Oxytetracycline
Oxytetracycline
Oxytetracycline
Oxytetracycline

IM
Drink
PO
Feed
IM
IM
PO
SC
Nebulize
Drink
IM
IM

PO
PO

PO
Drink
PO

Drink

NL
PO
PO

PO

Feed

Feed

Drink

Feed

Feed

Feed

ROUTE

QD-BID
QD
QD
QD
QD
QD-BID
QD-BID
QD
q4-6h
NL
QD
QD

Once
QW

QD
QD
q3w

QD

q2w
QD
QD

TID

QD

Once

QD

Once

Once

QD

DOSAGE
INTERVAL

A
E
E
E
E
E
E
E
A
A
G
A

G
G

E
E
G

D
D
D

266
1240
1240
704
1431
1492
1492
1503
876
802
401
55

590
1068

1650
1650
401

1479

1221
1470
1479

1446

564

846

585

860

825

1361

C.I.** REFERENCE

For respiratory infections


For respiratory disease
Add oxytetracycline feed also
Double dosage for birds below 5 kg

Add citric acid, therapeutic dosage

For chlamydophilosis

For capillariasis
For liver parasitic disease
For most intestinal worms including
tapeworms
For most intestinal worms including
tapeworms
For most intestinal worms
For most intestinal worms
Begin at age 4 months, alternate therapeutic
agent

For staphylococcal dermatitis

5-day slaughter withdrawal, prophylactic

Prophylaxis for Pasteurella multocida

For riemerellosis and colibacillosis

For Pasteurella multocida in ducklings

For coccidiosis

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

10
0.1-0.2 g/L
5

0.1-0.2 g/L

0.41 g/kg food

Crane

Ormetoprim +
Sulfadimethoxine
Ormetoprim +
Sulfadimethoxine
Ormetoprim +
Sulfadimethoxine
Ormetoprim +
Sulfadimethoxine
Ormetoprim +
Sulfadimethoxine
Ormetoprim +
Sulfadimethoxine

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

Chapter 9 | T H E R A P E U T I C A G E N T S

301

200
50
50
50-100
50-75
20
50-100
50-200
150

Oxytetracycline Amphoteric Anseriformes

Oxytetracycline Amphoteric Avian

Oxytetracycline Amphoteric Bird, Aquatic

Oxytetracycline Amphoteric Cockatoo, Goffin

Oxytetracycline Amphoteric Macaw, Blue and Gold

Oxytetracycline Amphoteric Ostrich

Oxytetracycline Amphoteric Psittacine

Oxytetracycline Amphoteric Raptor

Oxytetracycline Amphoteric Turkey

q3d

q3-5d

q2-3d

q3d

q2-3d

q3d

q3-5d

q3-5d

QD

q3d

QD

QD
QD
QD
q2d
q2d
q2d
QD
QD
QD
QD
QD
QD
q2-3d
TD
NL
Once
QD

DOSAGE
INTERVAL

A
A
E
E
E
E
C
C
C
C
A
E
E
E
A
A
E

727

1240

565

401

1170

380

1503

1648

1150

703

847

55
1067
704
704
1240
1240
564
564
564
705
55
1240
1365
1240
802
802
564

C.I.** REFERENCE

Long-lasting formulation

For pasteurellosis

Double dosage for birds below 5 kg

Causes irritation at injection site

For respiratory infections, may cause muscle


necrosis
For respiratory infections

For pasteurellosis and other bacteria

For chlamydophilosis

For chlamydophilosis
IM injection may cause muscle necrosis
Add oxytetracycline feed also
Add oxytetracycline drinking water also
3-day slaughter withdrawal, prophylactic

Add neomycin

Add tetracycline for birds over 700 g


Add tetracycline for birds under 400 g

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

SC

IM

IM-SC

IM

SC

IM-SC

SC

SC

IM

SC

75

IM
IM-SC
Drink
IM
IM
IM
Drink
PO
Feed
Drink
IM
IM
SC
IM-PO
Drink
Feed
Feed
IM

43
50
0.133-0.444 g/L
100
20
80
0.0265-0.106 g/L
6.25-200 mg TD
110-220 mg/kg food
0.06-0.25 g/L
58
50
50-100
25-50
2.5 g/L
2500 ppm
220 mg/kg food

ROUTE

60

Pheasant
Pigeon
Pigeon
Pigeon
Pigeon
Pigeon
Poultry
Poultry
Poultry
Poultry
Psittacine
Psittacine
Psittacine
Raptor
Turkey
Turkey
Turkey

Oxytetracycline
Oxytetracycline
Oxytetracycline
Oxytetracycline
Oxytetracycline
Oxytetracycline
Oxytetracycline
Oxytetracycline
Oxytetracycline
Oxytetracycline
Oxytetracycline
Oxytetracycline
Oxytetracycline
Oxytetracycline
Oxytetracycline
Oxytetracycline
Oxytetracycline

DOSAGE (mg/kg
unless otherwise
stated)

Oxytetracycline
Amazon Parrot
Amphoteric
Oxytetracycline Amphoteric Amazon, Blue-fronted

SPECIES

DRUG NAME

302
C l i n i c a l Av i a n M e d i c i n e - Vo l u m e I

3-5 IU/kg
0.5-1 IU TD

5 IU TD

100

2.5 ml/L spray


55
55

55
50 KIU/kg
44 KIU/kg
55-110 mg/kg food
375 KIU/L
110 mg/kg food
2.65 mg/kg food
<100 KIU/kg

100 KIU TD
100

Anseriformes
Avian

Avian

Avian

Ostrich

Avian

Avian

Avian

Anseriformes
Avian

Avian
Avian
Psittacine

Raptor

Anseriformes
Poultry
Poultry
Poultry
Poultry
Poultry

Raptor

Rhea
Turkey

Oxytocin
Oxytocin

Oxytocin

Oxytocin

Oxytocin

Paromomycin Sulfate

Penetran

Penetran

Penicillamine
Penicillamine

Penicillamine
Penicillamine
Penicillamine

Penicillamine

Penicillin
Penicillin
Penicillin
Penicillin
Penicillin
Penicillin

Penicillin

Penicillin G Benzathine
Penicillin G Benzathine

SC
IM

IM-IV

Parenteral
PO
Feed
Drink
Feed
Feed

PO

PO
PO
PO

PO
PO

Topical

Topical

PO

IV

NL

IV-SC

IM
IM

ROUTE

QD
QD

NL

NL
QD
QD
QD
QD
QD

BID

QD
BID
BID

BID
BID

NL

NL

BID

Once

NL

Once

NL
NL

DOSAGE
INTERVAL

G
A

G
C
C
C
C
E

F
G
E

D
D

D
E

582
385

1463

597
564
564
564
564
564

1240

1236
87
1240

1150
1221

1103

1486

1474

1257

1431

1151

1150
924

C.I.** REFERENCE

Add tylosin
Add penicillin G procaine for Pasteurella
multocida

Add streptomycin, nutritional use, no


slaughter withdrawal
Use crystalline formulation for bacterial
infections

Add streptomycin
Prophylactic

For copper toxicosis


Repeat after 3 to 5 days
Chelation agent for copper, zinc, mercury
and lead
For heavy metal poisoning

For heavy metal poisoning


For lead or zinc toxicosis, may use in
conjunction with edetate calcium disodium

For rashes, ulceration, local irritation, trauma,


bites, burns, etc.
For picking or itching

For neonate with cryptosporidiosis

Egg binding
Use with calcium and vitamin A for egg
expulsion
To help with egg expulsion, add calcium,
fluids and heat
For egg binding, give calcium borogluconate
also
Give 2 to 4 minutes before semen collection

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

52
55
50-55

2 IU/kg

5 U/kg

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

Chapter 9 | T H E R A P E U T I C A G E N T S

303

66-133 KIU/kg
20 KIU/kg
100
100

160-180

5
50
24

Avian
Falcon, Lanner
Galliformes
Turkey

Avian

Avian
Avian
Budgerigar

Canary
Chicken
Cockatoo, Major Mitchell's
Cowbird
Crane, European

Duck, Mallard
Duck, Northern Pintail
Eagle, Golden

Emu
Galliformes
Goose
Gull, California

Hawk
Penguin
Pigeon

Penicillin G Potassium
Penicillin G Potassium
Penicillin G Procaine
Penicillin G Procaine

Pentobarbital + Chloral
Hydrate + Magnesium
Sulfat e

Pentobarbital Sodium
Pentobarbital Sodium
Pentobarbital Sodium

Pentobarbital Sodium
Pentobarbital Sodium
Pentobarbital Sodium
Pentobarbital Sodium
Pentobarbital Sodium

Pentobarbital Sodium
Pentobarbital Sodium
Pentobarbital Sodium

Pentobarbital Sodium
Pentobarbital Sodium
Pentobarbital Sodium
Pentobarbital Sodium

Pentobarbital Sodium
Pentobarbital Sodium
Pentobarbital Sodium

IM
NL
IM

IV
PO
PO
IM

PO
IV
IM

IM
IM
IV
Feed
IM

IM
IM
IM

IM

IM
IM
IM
IM

ROUTE

PRN
Once
PRN

PRN
PRN
PRN
PRN

PRN
Once
PRN

PRN
PRN
NL
Once
PRN

PRN
PRN
PRN

PRN

NL
QID
q2d
Once

DOSAGE
INTERVAL

B
G
B

G
E
E
B

B
B
B

B
B
G
B
B

E
F
B

F
B
E
A

1086
595
1084

283
1130
1130
1084

1095
1593
1086

1084
1080
1590
1094
1084

1130
1209
1084

1209

1209
1175
111, 1473
385

C.I.** REFERENCE

Add chloral hydrate + magnesium sulfate,


reduce dose 15 to 20% in debilitated birds

"

Precede with ketamine by 15 minutes


Add chloral hydrate + magnesium sulfate,
reduce dose 15 to 20% in debilitated birds,
fledgling
Premedicate with diazepam
Use tablets
Use tablets
Add chloral hydrate + magnesium sulfate,
reduce dose 15 to 20% in debilitated birds

Add chloral hydrate + magnesium sulfate,


reduce dose 15 to 20% in debilitated birds

See above
Add thiopental sodium

Add chloral hydrate + magnesium sulfate,


reduce dose 15 to 20% in debilitated birds

Dosage base on combined mg of


pentobarbital/chloral hydrate/magnesium
sulfate

Loading dose, add penicillin G with procaine


benzathine for Pasteurella multocida

Post-surgical treatment of bumblefoot

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

14.7
33
24

13.3
50-100
50-100
24

22
390
18.2

24
16.2
100 mg TD
100-150 g/kg food
24

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

304
C l i n i c a l Av i a n M e d i c i n e - Vo l u m e I

15
dusting
dusting
1-5
3.5-7
0.048-0.080 g/L
3
< 30
20

2.2
3.5-7
3.5-7
2.5-5
0.2-2.5
75-100
4.31 mg/kcal
2.55 mg/kcal
10 g/L saline
10 g/L saline
100-200
150
100-200
200
90
100
100

Avian

Pigeon
Psittacine

Avian
Avian
Avian
Psittacine

Raptor
Raptor

Ostrich
Psittacine
Raptor

Avian
Raptor

Amazon Parrot
Avian
Avian
Avian
Avian
Avian
Avian
Bird, Aquatic
Budgerigar
Cockatoo, Citron-crested
Crane
Duck, Ruddy

Pentoxifylline

Permethrin
Permethrin

Phenobarbital
Phenobarbital
Phenobarbital
Phenobarbital

Phenobarbital
Phenobarbital

Phenylbutazone
Phenylbutazone
Phenylbutazone

Phytonadione
Phytonadione

Piperacillin Sodium
Piperacillin Sodium
Piperacillin Sodium
Piperacillin Sodium
Piperacillin Sodium
Piperacillin Sodium
Piperacillin Sodium
Piperacillin Sodium
Piperacillin Sodium
Piperacillin Sodium
Piperacillin Sodium
Piperacillin Sodium

IM
IM-IV
IM-IV
Flush
Nebulize
IM
IM
IM
IM
Parenteral
IM-IV-SC
IM

Parenteral
IM-PO

PO
PO
PO

PO
PO

PO
NL
Drink
PO

Topical
Topical

PO

Feed
PO
IM-IV
IM-IV
IV
IM

ROUTE

q4-6h
TID-QID
q4-6h
BID-QID
BID-QID
TID-QID
BID
BID
TID
BID
BID
BID

BID-QID
QD

QD
BID-TID
BID-TID

PRN
NL

BID
BID
PRN
BID

NL
NL

BID-TID

Once
PRN
PRN
PRN
PRN
PRN

DOSAGE
INTERVAL

A
E
E
E
E
E
G
E
A
G
E
G

E
E

G
E
E

E
D

E
D
G
E

E
E

B
E
E
B
G
B

1473
1180
1180
1183
1185
1650
55
1478
411
740
629
1468

1492
1433

710
1473
111

1463
1612

111, 1473
1475
58
1240

1240
1240

1489

1094
1463
1463
1075
1074
1080

C.I.** REFERENCE

Begin pre-operatively for tendon surgery

Add amikacin

Post-trauma infections

Synergistic with aminoglycosides


Synergistic with aminoglycosides
Nasal or sinus
10 to 30 minutes
Synergistic with aminoglycosides

For anticoagulant rodenticide


For anticoagulant poisoning

For feather picking, may cause deep sedation


and inability to perch
For sedation
For neurologic signs with organochlorine
toxicity

Control of seizures

For fleas and lice


Ectoparasite control

Add aloe vera for frostbite, vasodilator

Adult
Add thiopental sodium

For sedation
Not usually recommended

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

25-50 g/kg food


< 20
30
47
25 mg TD
16.2

Quail, Japanese
Raptor
Raptor
Skua, McCormick's
Swan, Mute
Turkey

Pentobarbital Sodium
Pentobarbital Sodium
Pentobarbital Sodium
Pentobarbital Sodium
Pentobarbital Sodium
Pentobarbital Sodium

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

Chapter 9 | T H E R A P E U T I C A G E N T S

305

100
100-200
100
50-100
100-200
100
150-200
200

45-200
100-500
4-5.26 g/L
0.3 g/L
100-500
1.9 g/L
500 mg
250 mg
12.5
35
1 g/L
100-500
250
30-50 mg TD
100
6.25 g/L

0.5
1 mg TD

Pigeon
Pigeon
Psittacine
Psittacine
Psittacine
Raptor

Avian

Falcon, Peregrine

Anseriformes
Avian
Crane
Finch
Galliformes
Pigeon
Pigeon
Pigeon
Pigeon
Pigeon
Poultry
Poultry
Psittacine
Quail
Raptor

Raptor

Crane

Amazon Parrot

Piperacillin Sodium
Piperacillin Sodium
Piperacillin Sodium
Piperacillin Sodium
Piperacillin Sodium
Piperacillin Sodium

Piperacillin Sodium +
Tazobactam Sodium
Piperacillin Sodium +
Tazobactam Sodium

Piperazine
Piperazine
Piperazine
Piperazine
Piperazine
Piperazine
Piperazine
Piperazine
Piperazine
Piperazine
Piperazine
Piperazine
Piperazine
Piperazine
Piperazine

Piperonyl Butoxide

Piroxicam

Policosanol

PO

PO

Topical

PO
PO
Drink
Drink
PO
Drink
Drink
Drink
Drink
PO
Drink
PO
PO
PO
PO

IM

IM-IV

IM
IM
IM
SC
IM-IV
IM-IV

IM
IM
IM
Parenteral

ROUTE

BID

BID

NL

NL
q2w
QD
NL
q2w
QD
TD
TD
QD
QD
QD
q10d
NL
NL
NL

BID

QD-BID

BID-TID
BID
BID
TID
BID-TID
BID

TID-QID
BID
BID
q4d

DOSAGE
INTERVAL

E
E
G
E
E
C
C
C
E
G
G
G
G
G
E

G
G
A
E
E
E

E
E
G
G

1273

1671

1068

111
1650
596
1572
111
704
706
706
1240
260
57
1309
57
678
57, 1463

1426

1279

260
590
411
632
1240, 1756
1433

1027
1357
1620
820

C.I.** REFERENCE

For hyperlipidemia or hypercholesterolemia

Add permethrin + methoprene for


ectoparasites

Anthelmintic
Anthelmintic

For ascarids

For 30 birds
For capillaria
For ascaridiasis
Repeat every 10 to 14 days

For roundworms
Repeat in 2 weeks

Substitute for piperacillin sodium, DO NOT


use aminoglycosides concurrently

Neonate dosage

For embryonic death, begin first dose at day


14, use 26 ga needle

Broad spectrum

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

200
100
100
4 mg TD per egg

Falcon
Gull
Lorikeet, Rainbow
Macaw

Piperacillin Sodium
Piperacillin Sodium
Piperacillin Sodium
Piperacillin Sodium

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

306
C l i n i c a l Av i a n M e d i c i n e - Vo l u m e I

50 mg TD
12.5 mg TD
20 mg TD

80
80
80
0.3
0.1-0.3

Crane, Demoiselle

Pheasant, Peacock

Vulture, King

Cockatoo, Umbrella
Parrot, Grey
Pigeon

Avian
Avian

Polysulfated
Glycosaminoglycan
Polysulfated
Glycosaminoglycan
Polysulfated
Glycosaminoglycan

Potassium Bromide
Potassium Bromide
Potassium Bromide

Potassium Chloride
Potassium Chloride

10-100

Avian

Pralidoxime Iodide

Parenteral

IM
NL
IM

NL

IV
IV

PO
PO
PO

IM

IM

IA

IM-PO
PO
Drink
PO
Drink
Feed
Drink
Feed
Feed
Drink
Drink
Feed

PO

ROUTE

NL

QD
BID-QID
PRN

Once

NL
NL

QD
QD
QD

QW

Once

Once

NL
BID
NL
BID
QD
QD
NL
Once
QD
QD
NL
Once

QD

DOSAGE
INTERVAL

E
E
G

E
E

G
G
G

E
E
E
E
E
E
E
E
E
E
E
E

1492

111
1400
50

1029

1473
111

1691
1274
1274

579

579

579

924
1180
1180
565
695
695
1187
1187
1437
1437
1187
1187

1466

C.I.** REFERENCE

Reduce dosage if used with atropine for


organophosphates

For organophosphate poisoning


Continue only if first dose produces response

Add formaldehyde for fumigation TOXIC

For control of seizures


Seizure control
Seizure control

Musculosketal joint therapy

Musculosketal joint therapy

Musculosketal joint therapy

Add drug to drink at the same time


Add drug to food at the same time

Mix with lactulose for hyperlipidemia of


triglyceride and cholesterol

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

10-30
100
20

Avian
Raptor
Raptor

Pralidoxime Chloride
Pralidoxime Chloride
Pralidoxime Chloride

14 g/m

10-15
1000 mg/kcal
3000 KIU/L
50 KIU/kg
50 KIU/L
50 KIU/kg food
500 KIU/L
500 KIU/kg food
100 KIU/kg food
100 KIU/L
500 KIU/L
500 KIU/kg food

Avian
Avian
Avian
Avian
Canary
Canary
Canary
Canary
Passerine
Passerine
Passerine, Small
Passerine, Small

Polymyxin B Sulfate
Polymyxin B Sulfate
Polymyxin B Sulfate
Polymyxin B Sulfate
Polymyxin B Sulfate
Polymyxin B Sulfate
Polymyxin B Sulfate
Polymyxin B Sulfate
Polymyxin B Sulfate
Polymyxin B Sulfate
Polymyxin B Sulfate
Polymyxin B Sulfate

Potassium Permanganate Falcon

Amazon, Yellow-naped

Policosanol

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

Chapter 9 | T H E R A P E U T I C A G E N T S

307

100
100
100
10-20
10-20
9

7.5
5
10
10-20
11.4
10-20
10
9
10-20
50
30
5-10
10-50
2
6.7

Raptors

Anseriformes
Psittacine

Anseriformes
Avian
Avian

Avian
Bird, Aquatic
Bustard
Finch
Finch

Ostrich
Ostrich
Passerine, Small
Penguin
Pigeon
Pigeon
Pigeon
Psittacine
Psittacine
Raptor
Raptor
Raptor
Raptor

Avian
Avian

Psittacine
Raptor
Raptor

Pralidoxime Iodide

Pralidoxime Mesylate
Pralidoxime Mesylate

Praziquantel
Praziquantel
Praziquantel

Praziquantel
Praziquantel
Praziquantel
Praziquantel
Praziquantel

Praziquantel
Praziquantel
Praziquantel
Praziquantel
Praziquantel
Praziquantel
Praziquantel
Praziquantel
Praziquantel
Praziquantel
Praziquantel
Praziquantel
Praziquantel

Prednisolone
Prednisolone

Prednisolone
Prednisolone
Prednisolone

PO
IM
IM-IV

PO
PO

PO
PO
NL
PO
SC
PO
PO
IM
PO
PO-SC
NL
PO-SC
PO

PO
PO
PO-SC
PO
Feed

PO-SC
PO
IM

IM
IM

IM

Parenteral

ROUTE

BID
Once
Once

BID
NL

NL
NL
NL
NL
QM
q2w
NL
NL
Once
NL
q10d
QD
q2w

NL
NL
Once
q10-14d
Once

q10d
QD
QD

QID
QID

Once

BID-TID

DOSAGE
INTERVAL

E
E
E

E
E

C
G
E
E
E
E
E
E
E
E
E
E
E

E
E
E
E
E

D
D
D

D
E

1240
1400
1400

1431
1526

283
481
1187
1478
704
704
1192
763
1240
1068
1132
1240
1359

1648
1503
1240
1572
1617

1150
1470
1470

1150
1240

1093

1650

C.I.** REFERENCE

For shock

Also analgesic

May predispose to mycotic infection


Use decreasing dosage for long-term therapy

For tapeworms

Tablet crushed in water suspension


For cestodes
For tapeworms
For tapeworms repeat after 10 days
For trematodes and cestodes
For tapeworms and flukes

For trematodes
For cestodes

Crush tablet and mix with enough food for 1


day, scatter throughout aviary

Control cestodes
For liver parasitic disease
Continue PO for 11 days for liver parasitic
disease
For tapeworms
For tapeworms
For cestodes and trematodes

For organophosphate toxicity

Use lower dosage if used with atropine for


organophosphate toxicity
For monocrotophos toxicity

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

2
0.5-1
2-4

10
10
10
10-20
12 mg/kg

10-100

Avian

Pralidoxime Iodide

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

308
C l i n i c a l Av i a n M e d i c i n e - Vo l u m e I

2-4
10-30

0.5-1
10-20

0.03
1
1
0.3-1
0.75
0.03
0.03
1
1
1
1

125 mg TD
125

200

125
21 ml/kg food

Avian

Raptor

Avian

Avian

Avian
Avian
Avian
Avian

Falcon
Penguin
Penguin
Penguin
Psittacine
Raptor
Raptor

Amazon Parrot
Raptor

Avian

Macaw

Anseriformes

Anseriformes

Avian

Primaquine Phosphate
Primaquine Phosphate
Primaquine Phosphate
Primaquine Phosphate

Primaquine Phosphate
Primaquine Phosphate
Primaquine Phosphate
Primaquine Phosphate
Primaquine Phosphate
Primaquine Phosphate
Primaquine Phosphate

Primidone
Primidone

Probenecid

Probenecid

Probiotic

Probiotic

Probiotic

Feed

Drink

Feed

PO

NL

Drink
PO

NL
PO
PO
PO
PO
PO
PO

PO
PO
PO
PO

IM-IV

IM-IV

IM-IV

IM-IV

IM-IV

ROUTE

Once

NL

Once

QID

q2d

QD
PRN

Once
QW
QD
QD
QD
QD
QW

QD
QW
QW
TID

NL

Once

PRN

NL

NL

DOSAGE
INTERVAL

G
E

E
D
E
B
E
G
G

D
E
E
G

111

1240

1240

45

704

1753
1463

1177
1470
111, 1473
262
1365
61
94

1470
1479
1492
57

1554

1151

234

111

111

C.I.** REFERENCE

Add to hand feeding formula

For hand-rearing (6 hours old) and


convalescing birds, Avipro Pediatric
Double dosage for stressed bird, Avipro

For body weight > 200g, to decrease


excretion rate of penicillin/cephalosporin
during therapy
Uricosiuric

Long-term seizure control


For sedation

Add chloroquine phosphate


For sarcocystosis
Add chloroquine
Add chloroquine phosphate, juvenile dosage

Add chloroquine
For liver parasitic disease prophylaxis

Add chloroquine for Plasmodium


Usually in combination with chloroquine

For liver parasitic disease

For shock

For neurologic emergencies

Immunosuppressive

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

5 cc/L

5 scoops/L

0.5-1

Avian

Prednisolone Sodium
Phosphate
Prednisolone Sodium
Phosphate
Prednisolone Sodium
Phosphate

Prednisolone Sodium
Succinate
Prednisolone Sodium
Succinate

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

Chapter 9 | T H E R A P E U T I C A G E N T S

309

5 ml/L food
pinch TD

30 mg TD
5
5
5

4.1-8.6
14
1.33
6
10
30 mg TD
0.2
0.04
N/A

2.5 ml/kg

Psittacine

Psittacine
Psittacine
Ratite

Avian

Avian

Raptor

Amazon, Hispaniolan

Anseriformes
Avian

Duck, Mallard

Ostrich

Pigeon
Pigeon
Psittacine
Swan
Swan (Black, Mute)

Chicken

Avian
Avian

Raptor

Avian

Probiotic

Probiotic
Probiotic
Probiotic

Proflavine

Propentofylline

Propentofylline

Propofol

Propofol
Propofol

Propofol

Propofol

Propofol
Propofol
Propofol
Propofol
Propofol

Propolis

Propranolol HCl
Propranolol HCl

Prostaglandin E (See
Dinoprostone)

Psyllium Hydrophilic
Mucilloid

PO

Topical

IM
IV

IV
IV
IV
IV
IV

IV

IV

IV
IV

IV

PO

PO

Topical

Feed
PO
PO

Drink

Feed
Feed

ROUTE

NL

PRN

NL
NL

Once

PRN
PRN
PRN
Once
PRN

PRN

PRN

PRN
PRN

PRN

BID

QD

QD-BID

Once
QD
NL

NL

QD
Once

DOSAGE
INTERVAL

E
E

B
B
E
G
B

E
E

E
E
G

E
E

87

1400

111
111

1632

779
779
1240
1695
1291

1628

1358

1190
1181

1436

1400

1240

1240

1473
1473
418

1240

111
1240

C.I.** REFERENCE

Mix with syringeable food, bulking agent to


remove GI materials

For egg binding, use gel formulation

Immune and growth stimulant

Maintain anesthesia by continuous infusion at


1 mg/kg per minute
Induction agent
Short duration, smooth induction, high safety
margin
Administer over 1 minute, follow with 4
mg/kg, respiratory depression
Maintain with 0.2 mg/kg/min constant rate
infusion
Follows ketamine
Preliminary to inhalation anesthesia
For anesthesia induction
Induction for isoflurane
Gas anesthesia premed

Vasodilator for wing tip edema or dry


gangrene
Improve circulation (wing tip edema)

For wounds, stimulate granulation

Hand feeding formula

For hand-rearing (6 hours old) and


convalescing birds, Avipro Pediatric
Double dosage for stressed bird, Avipro

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

10

8
1.33-14

5 scoops/L

1 pinch TD
21 ml/kg food

Avian
Psittacine

Probiotic
Probiotic

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

310
C l i n i c a l Av i a n M e d i c i n e - Vo l u m e I

7
4.5-25
4.5
4.5
100
20-25
4.5
100
20
4.5
5-7
0.1% powder
0.5-2% mixture
0.25-0.5
0.5
0.3
0.25-0.5
0.5
0.06 g/L
0.06 g/L

5-10
240
7.5
240
10 mg TD
5-10
10 drops/kg

Anseriformes
Avian
Crane
Finch
Passerine
Pigeon
Psittacine
Psittacine
Raptor
Raptor
Ratite

Crane
Finch
Raptor

Anseriformes
Avian
Avian
Raptor

Raptor

Anseriformes

Psittacine

Avian
Avian
Avian
Canary
Pigeon
Psittacine

Avian

Pyrantel Pamoate
Pyrantel Pamoate
Pyrantel Pamoate
Pyrantel Pamoate
Pyrantel Pamoate
Pyrantel Pamoate
Pyrantel Pamoate
Pyrantel Pamoate
Pyrantel Pamoate
Pyrantel Pamoate
Pyrantel Pamoate

Pyrethrin
Pyrethrin
Pyrethrin

Pyrimethamine
Pyrimethamine
Pyrimethamine
Pyrimethamine

Pyrimethamine

Pyrimethamine +
Sulfaquinoxaline
Pyrimethamine +
Sulfaquinoxaline

Quinacrine HCl
Quinacrine HCl
Quinacrine HCl
Quinacrine HCl
Quinacrine HCl
Quinacrine HCl

Red Clover

PO

PO
NL
PO
PO
PO
PO

Drink

Drink

PO

PO
PO
PO
PO

Topical
Topical
Topical

PO
PO
PO
PO
PO
PO
PO
PO
PO
PO
PO

Feed

ROUTE

QD

QD
QD
QD
BID
QD
QD

QD

QD

BID

BID
BID
NL
BID

QW-q2w
QD
q10d

q2w
q2w
q10d
q10-14d
Once
QW-q2w
q10d
NL
Once
q2w
NL

Once

DOSAGE
INTERVAL

E
E
E
G
G
E

D
D
E
E

E
E
G

E
D
E
E
G
E
E
G
E
G
G

1435

111
1479
1650
57
47
1473

1240

1150

1433

1150
1470
1650
1400

1361
1572
1411

1358
111,1221, 1473
1361
1572
1335
1364
1240
57, 1335
1240, 1400
94
418

1478

C.I.** REFERENCE

Use low alcohol formulation for soft shelled


egg

For Plasmodium
For Plasmodium

Wait 2 days then repeat for coccidiosis

2 days off, then repeat for coccidiosis

For Leucocytozoo, Plasmodium


For sarcocystosis, toxoplasmosis and other
protozoal infections
For leucocytozoonosis

For sarcocystosis and toxoplasmosis

For ectoparasites, apply lightly


Dust feathers
For chewing lice

For nematodes
Juvenile dosage

For nematodes

For intestinal nematodes

For nematodes
For nematodiasis
For intestinal nematodes

Add sodium + magnesium sulfate + mineral


oil for lead poisoning, add bran

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

40 ml/L soft food

Bird, Aquatic

Psyllium Hydrophilic
Mucilloid

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

Chapter 9 | T H E R A P E U T I C A G E N T S

311

10-60 drops/kg
2 drops TD

2-4
130
15
1.15 mg/kcal

45
10-20
15
20
45
15
30

0.1 g/L
33 mg/kg food
0.033 g/kg
0.323 mg/kcal
0.65 g/L
1 g/L
6-10
1 g/L
0.4 g/L
0.4 g/kg food
0.1 g/L
6-10
0.05 g/kg food

Avian

Finch

Raptor

Ostrich

Avian

Avian

Amazon, Yellow-cheeked
Avian
Avian

Bustard, Houbara
Crane, Whooping
Psittacine
Raptor

Poultry

Chicken
Pheasant, Ring-necked

Avian
Avian
Avian
Avian
Budgerigar
Canary
Canary
Finch
Finch
Finch

Red Palm Oil

Rescue Remedy

Reserpine

Resorantel

Rifabutin

Rifabutin

Rifampin
Rifampin
Rifampin

Rifampin
Rifampin
Rifampin
Rifampin

Rimantadine HCl

Robenidine HCl
Robenidine HCl

Ronidazole
Ronidazole
Ronidazole
Ronidazole
Ronidazole
Ronidazole
Ronidazole
Ronidazole
Ronidazole
Ronidazole

PO
Drink
Drink
PO
Drink
Drink
Feed
Drink
PO
Feed

Feed
Feed

Drink

PO
PO
PO
PO

NL
PO
PO

PO

PO

PO

PO

PO

PO

ROUTE

QD
NL
QD
QD
QD
QD
Once
QD
QD
QD

QD
QD

NL

BID
QD
BID
TID

QD
BID
QD

QD

QD

NL

PRN

Once

QD

DOSAGE
INTERVAL

E
E
E
G
E
E
E
E
E
G

E
B

G
G
E
B

G
E
G

1180
1180
1479
57
1479
695
1187
1572
1572
1334

564
895

435

932
207
1240
1178

713
111, 1473
1154

1180

1470

283,401, 524

1463

1723

1727

C.I.** REFERENCE

For cochlosomiasis

Treat 4 times yearly for Trichomoniasis

Treat 4 times yearly for Trichomoniasis

For flagellates

7-day slaughter withdrawal, prophylactic


For coccidiosis

Add ciprofloxacin + ethambutol for


mycobacteriosis
For bacterial diarrhea
Add ethambutol
For avian tuberculosis
Add IT and IV amphotericin B + flucytosine
for aspergillosis

Add ethambutol + isoniazid

Add ethambutol + enrofloxacin for


mycobacteriosis
Add ethambutol + azithromycin or
clarithromycin for mycobacteriosis

Add fenbendazole or levamisole

For prolonged sedation

For stress of handling or minor procedures

May give over food

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

312
C l i n i c a l Av i a n M e d i c i n e - Vo l u m e I

Topical

Feed
Feed
Feed
Feed
Feed
Feed

12.5
10
0.1 g/L
25-50 mg/kg food

0.06 g/kg
0.075 g/kg
60
44-66 mg/kg food
60 ppm
60 g/ton
10
8
0.02 g/L
0.05 g/L
0.025-0.03
5 g/L bait
25
0.06

Pigeon
Pigeon

Pigeon

Pigeon
Pigeon
Pigeon

Poultry

Psittacine

Chicken
Chicken
Chicken
Chicken
Pheasant, Ring-necked
Poultry

Chicken
Chicken
Chicken
Turkey

Blackbird, Red-winged
Dove
Duck, Mallard

Psittacine

Chicken

Ronidazole

Ronidazole
Ronidazole
Ronidazole

Roxarsone

Salicylic Acid

Salinomycin
Salinomycin
Salinomycin
Salinomycin
Salinomycin
Salinomycin

Sarafloxacin HCl
Sarafloxacin HCl
Sarafloxacin HCl
Sarafloxacin HCl

Secobarbital Sodium
Secobarbital Sodium
Secobarbital Sodium

Selenium

Semduramycin

PO

NL

PO
Feed
PO

PO
Drink
Drink
Drink

Feed

Drink
PO
Drink

Drink

NL
Drink

QD

q3d-q2w

PRN
Once
PRN

BID-TID
QD
QD
NL

QD
QD
QD
QD
Once
QD

q2w

QD

QD
NL
NL

NL

QD
QD

QD
QD

DOSAGE
INTERVAL

G
G
B

A
B
B
A

B
B
B
E
B
C

E
E
E

D
E

G
D

564

1613

1769
1763
1095

787
855
864
805

869
869
958
564
783
705

1446

564

1240
1432
1432

1192

1221
1192

1334
1438

C.I.** REFERENCE

Add chloralose
Bait is usually corn

Continuous or 4-hour pulse dose


For Escherichia coli infections

Preventive for coccidiosis


Preventive for coccidiosis
For coccidial prophylaxis
No slaughter withdrawal, prophylactic
For coccidiosis
For coccidiosis

Add 3 g tannic acid + 3 g salicylic acid +


ethyl alcohol for 100 ml of solution for
dermatomycosis

Nutritional use, no slaughter withdrawal

For trichomoniasis treatment


"
"

For cochlosomiasis
For trichomoniasis, giardiasis and
cochlosomiasis
For trichomoniasis
For hexamitiasis, add trimethoprim or
enrofloxacin in severe infections
For treatment of trichomoniasis, give
periodically for 2 to 3 days for prophylaxis

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

0.1-0.2 g/L

6-10
0.1 g/L

Drink
Drink

Ronidazole
Ronidazole

0.05 g/L
0.04 g/L

Finch
Passerine

ROUTE

Ronidazole
Ronidazole

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

Chapter 9 | T H E R A P E U T I C A G E N T S

313

PO
Drink

IO-IV
PO
Gavage

2 drops/kg
40 drops/L
1 mEq/kg

5 mEq/kg
30 ml/kg
10 g/L

1-2% solution

30 ml/L

60
67-200
2 mg TD
134-200
67
50 ml/kg

Avian
Avian

Avian

Avian

Avian

Avian
Bird, Aquatic

Bird, Aquatic
Bird, Aquatic

Penguin
Psittacine

Raptor

Finch

Avian
Avian
Budgerigar
Budgerigar
Budgerigar

Avian

Avian

Silver, Colloidal
Silver, Colloidal

Sodium Bicarbonate

Sodium Bicarbonate

Sodium Bicarbonate

Sodium Chloride
Sodium Chloride

Sodium Chloride
Sodium Chloride

Sodium Chloride
Sodium Chloride

Sodium Chloride

Sodium Hypochlorite

Sodium Iodide
Sodium Iodide
Sodium Iodide
Sodium Iodide
Sodium Iodide

Sodium Lactate Solution

Sodium Lactate Solution

IV

IV

IM
IM
IM
IM
IM

Topical

Topical

PO
IM-IV-SC

Feed
PO

IV

IV-SC

NL

NL

PRN
NL
PRN
QD
QD

NL

NL

QD
QD

QD
NL

TID-QID
QD

Once

NL

PRN

QD
QD

q10d

BID

DOSAGE
INTERVAL

G
F
G
G
G

G
E

E
E

E
D

E
E

1650

111

54
1209
85
1212
1212

1572

1400

1353
1240

1501
1503

1151
1559

1311

1473

1309

1435
1435

1650

1154

C.I.** REFERENCE

Emergency care, give slowly, warm fluid

Maintenance fluids

For acute thyroid hyperplasia


For chronic thyroid hyperplasia

For salmonellosis environmental cleanup, use


household bleach

1-2% solution for wounds, wash off within 5


minutes

Supplement fish diet


Use 0.9% solution

Use 0.9% solution


To maintain activity of salt gland of marine
birds kept on freshwater
For pelagic sea birds kept in fresh water
For procelliform birds kept in fresh water

Give slowly over 15 to 30 minutes, do not


exceed 4 mEq/kg
For cardiopulmonary resuscitation

First dose IV, remainder SC, maximum total


dose 4 mEq/kg for metabolic acidosis

Broad spectrum
Broad spectrum

For cautery of papillomas

Add lamprene + ethambutol HCl, add


ciprofloxacin or enrofloxacin or streptomycin
for advanced cases

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

10-30 ml/kg

150-1667
50 ml/kg

100
100

1-4 mEq/kg

Topical

Avian

Silver Nitrate

PO

10

Avian

Seromycin

ROUTE

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

314
C l i n i c a l Av i a n M e d i c i n e - Vo l u m e I

20 ml/kg
50 ml/kg
50-100 ml/kg

2000
500-1000
125-250
0.003
30
1 g/L
10-45
0.58 mg/kcal
1 g/L
0.2-0.4 g/L
5 mg TD
2 g/L
0.5 g/L
5
0.2-0.4 g/L
0.4 g/kg food
0.2-0.4 g/L
0.4 g/kg soft food
0.4 g/kg food
0.2-0.4 g/L
25
30
0.15-0.25 g/L
0.264-0.53 g/L
0.132 g/L
2.5-20 mg TD
10-30
35

Hawk, Red-tailed
Lory, Red
Psittacine

Avian
Avian

Avian

Toucan, Sulfur-breasted

Avian
Avian
Avian
Avian
Avian
Canary
Chicken
Chicken
Chicken
Duck
Finch
Finch
Passerine
Passerine
Passerine, Small
Passerine, Small
Pigeon
Pigeon
Pigeon
Poultry
Poultry
Poultry
Psittacine
Psittacine

Sodium Lactate Solution


Sodium Lactate Solution
Sodium Lactate Solution

Sodium Sulfate
Sodium Sulfate

Sodium Sulfate

Somatostatin

Spectinomycin HCl
Spectinomycin HCl
Spectinomycin HCl
Spectinomycin HCl
Spectinomycin HCl
Spectinomycin HCl
Spectinomycin HCl
Spectinomycin HCl
Spectinomycin HCl
Spectinomycin HCl
Spectinomycin HCl
Spectinomycin HCl
Spectinomycin HCl
Spectinomycin HCl
Spectinomycin HCl
Spectinomycin HCl
Spectinomycin HCl
Spectinomycin HCl
Spectinomycin HCl
Spectinomycin HCl
Spectinomycin HCl
Spectinomycin HCl
Spectinomycin HCl
Spectinomycin HCl

NL
BID

DOSAGE
INTERVAL

PO
Drink
IM
IM-SC
Drink
Drink
SC
Drink
Drink
SC
Drink
Feed
Drink
Feed
Feed
Drink
IM-SC
PO
Drink
Drink
Drink
SC
IM
IN

SC

PO

PO
PO

QD
QD
NL
TID
NL
NL
Once
NL
NL
Once
QD
QD
QD
QD
Once
NL
TID
QD
NL
QD
QD
QD
BID-TID
NL

BID

NL

QD
NL

IV
NL
SC
NL
IO-IP-IV-SC NL

IO-IV-SC
IO-IV-SC

ROUTE

E
E
E
E
E
E
B
C
C
B
E
E
E
E
E
E
E
F
G
C
C
C
E
E

E
E

G
G
E

G
G

565
704
704
1180
1180
1187
848
1307
1307
841
1572
1572
1437
1437
1187
1187
565, 1061
1061
260
564
564
564
1240
1240

589

1746

111
1554

1626
1621
1688

1311
1756

C.I.** REFERENCE

Prophylactic
Chick dosage
Gram negative enteritis
Give 1/3 each nare, remainder IM

Add drug to food at the same time


Add drug to drink at the same time

Day-old neonates
For Mycoplasma gallisepticum in broilers
For improved weight gain in broilers
For E. coli and Salmonella

For removal of metals from GI tract

Large birds, give slurry


For botulism to flush gastrointestinal tract

For hyperuricemia, give until level drops to


normal
Supportive therapy post-trauma
Intra-operative fluids

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

25 ml/kg
50-100 ml/kg

Avian
Avian

Sodium Lactate Solution


Sodium Lactate Solution

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

Chapter 9 | T H E R A P E U T I C A G E N T S

315

10 mg TD

250
100
2 g/L
0.58 mg/kcal
1.08 mg/kcal
0.2-0.4 g/L
400 mg/kg food
0.2-0.4 g/L
0.4 g/kg food
25
50
0.4 g/L
20
25-50
25-50
25-50
0.016 g/L
0.5-1
10-30
33
15
0.65 mg/kcal
1.28-4.67 mg/kcal
10-30
30

Turkey

Avian
Avian
Avian
Avian
Avian
Canary
Canary
Passerine, Small
Passerine, Small
Pigeon
Pigeon
Poultry
Raptor

Avian
Avian
Avian
Psittacine
Psittacine

Avian
Avian
Avian
Avian
Avian
Avian
Avian

Avian

Chicken
Chicken
Pheasant
Pheasant

Spectinomycin HCl

Spiramycin
Spiramycin
Spiramycin
Spiramycin
Spiramycin
Spiramycin
Spiramycin
Spiramycin
Spiramycin
Spiramycin
Spiramycin
Spiramycin
Spiramycin

Stanozolol
Stanozolol
Stanozolol
Stanozolol
Stanozolol

Streptomycin Sulfate
Streptomycin Sulfate
Streptomycin Sulfate
Streptomycin Sulfate
Streptomycin Sulfate
Streptomycin Sulfate
Streptomycin Sulfate

Streptomycin Sulfate

Streptomycin Sulfate
Streptomycin Sulfate
Streptomycin Sulfate
Streptomycin Sulfate

IM
PO
Feed
Feed

IM

IM
IM
IM-PO
IM
PO
IM
IM

IM
IM
IM
Drink
Parenteral

PO
IM-PO
Drink
IM
PO
Drink
Feed
Drink
Feed
IM
PO
Drink
IM

SC

IM
SC

ROUTE

QD
QD
QD
QD

BID

BID-TID
BID-TID
NL
BID-TID
QD
BID-TID
BID

q3d-QW
q3-4d
q3d-QW
NL
NL

QD
NL
NL
QD
QD
QD
QD
NL
Once
QD
QD
QD
NL

NL

BID
NL

DOSAGE
INTERVAL

A
E
G
G

E
E
E
E
E
E
G

E
E
G
E
E

E
E
E
E
E
E
E
E
E
E
F
C
E

G
C

320
565
678
678

819

111
741
924
1180
1180
1470
55, 1154

111, 1209, 1240


1473
1309
763
763

565
924
1180
1180
1180
695
695
1187
1187
565, 1061
1061
564
1463

1307

234
1307

C.I.** REFERENCE

Add ethambutol + rifampin for


mycobacteriosis
Add rifampin + ethambutol for avian
tuberculosis

Used in large birds and poultry


Poor spectrum

Anabolic agent
For debilitation, anorexia and anemia
For debilitation, anorexia and anemia

For bacterial infections

Dilute 1:4 normal saline for newly hatched


chicks
Inject in base of the neck of 1 to 3-day-old
poults for airsacculitis

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

25-50
50-100
220 mg/kg food
55-110 mg/kg food

10

50
12.5-25 mg TD

Raptor
Turkey

Spectinomycin HCl
Spectinomycin HCl

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

316
C l i n i c a l Av i a n M e d i c i n e - Vo l u m e I

55-110 mg/kg food


15

25-35
30
30
25-35
15-35
25-35
30
25

25
24
25
< 5 ml/kg 5% soln
0.175 g/L
0.125 ml powder

Quail
Raptor

Avian
Avian
Avian
Avian
Avian
Bird, Aquatic
Psittacine
Raptor

Avian
Lorikeet, Rainbow
Psittacine

Raptor

Avian
Avian

Avian

Avian
Canary

Canary
Canary
Passerine

Streptomycin Sulfate
Streptomycin Sulfate

Succimer
Succimer
Succimer
Succimer
Succimer
Succimer
Succimer
Succimer

Sucralfate
Sucralfate
Sucralfate

Sucrose

Sulfachlorpyridazine
Sulfachlorpyridazine

Sulfachlorpyridazine

Sulfachlorpyridazine
Sulfachlorpyridazine

Sulfachlorpyridazine
Sulfachlorpyridazine
Sulfachlorpyridazine

Drink
Drink
Drink

Drink
Drink

Drink

Drink
Drink

PO

PO
PO
PO

PO
PO
PO
PO
PO
PO
NL
PO

Feed
PO

PO
IM
PO
Drink
Feed

ROUTE

QD-q2d
NL
QD

QD
QD-q2d

QD

QD
QDlllllll

PRN

TID
BID
TID

BID
QD
BID
BID
BID
BID
NL
BID

QD
NL

QD
QD
QD
QD
QD

DOSAGE
INTERVAL

E
E
G

G
E

E
G

E
G
E

D
E
E
E
G
D
G
E

G
E

E
F
C
C
E

1187
1187
1334

57
1187

1479

1240
1309

1400

1492
1620
111

1221, 1470
1120
1151
1236
1337
1478
1710
1359

678
1463

565, 1061
1061
564
564
564

C.I.** REFERENCE

Give 5 days of each week, continue until after


molting

Give 5 days per week for coccidiosis

Antibacterial,* use 5-10 days


Antibacterial*
*Vetisulid Oral Powder is 560 mg/ml
volume for flock treatment for E. coli
Use 5 days per week, reduces shedding of
Atoxoplasma
Repeat after 2 days, antiparasitic
Give 5 days per week until molting complete
in juveniles with atoxopasmosis

Mild purgative, may stimulate appetite

Mix with water for GI bleeding


For intestinal ulcers

For zinc toxicity


After 2 days off, repeat over 3-5 weeks for
lead toxicity

Preferred oral drug for lead toxicosis


For zinc toxicoses
Metal chelating agent
Give 5 days per week for lead toxicosis
For lead poisoning

May give with kaolin or sulfonamide for


bacterial infections

Add penicillin, nutritional use, no slaughter


withdrawal

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

0.3 g/L
0.15-.0.3 g/L
0.15 g/L

0.4 g/L
0.15 g/L

59 g/L

100-200
25-50
55
0.068-0.1 g/L
13.2 mg/kg food

Pigeon
Pigeon
Poultry
Poultry
Poultry

Streptomycin Sulfate
Streptomycin Sulfate
Streptomycin Sulfate
Streptomycin Sulfate
Streptomycin Sulfate

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

Chapter 9 | T H E R A P E U T I C A G E N T S

317

1% cream formula
300-400

24
25
0.5 g/L
50
25 (50 loading dose)
25
25
250
0.5 g/L
0.19-0.25 g/L
0.25-0.5 g/L
25
25-50
1
0.3
0.5
2 g/L
30
0.2 g/L
50
1 g/L

Psittacine

Penguin, African

Avian
Avian
Chicken

Crane
Falcon
Gull
Pigeon
Pigeon
Pigeon
Pigeon
Poultry
Raptor
Raptor

Avian

Avian

Psittacine

Avian

Avian
Avian
Avian
Avian

Avian

Sulfadiazine, Silver

Sulfadiazine,
Sulfamerazine,
Sulfamethazine

Sulfadimethoxine
Sulfadimethoxine
Sulfadimethoxine

Sulfadimethoxine
Sulfadimethoxine
Sulfadimethoxine
Sulfadimethoxine
Sulfadimethoxine
Sulfadimethoxine
Sulfadimethoxine
Sulfadimethoxine
Sulfadimethoxine
Sulfadimethoxine

Sulfadoxine +
Pyrimethamine
Sulfadoxine +
Pyrimethamine
Sulfadoxine +
Pyrimethamine
Sulfamerazine

Sulfamethazine
Sulfamethazine
Sulfamethazine
Sulfamethazine

Sulfamethazine

Drink

IM-SC
Drink
PO
Drink

Drink

PO

PO

PO

PO
PO
PO
PO
IM
Drink
Drink
Drink
NL
PO

IM
IM-PO
Drink

Feed

Topical

Drink
Drink
Drink

ROUTE

NL

NL
QD
NL
NL

QD

BID

NL

QW

QD
QD
BID
BID
BID
QD
QD
QD
QD
QD

NL
NL
NL

BID

NL

NL
QD
QD

DOSAGE
INTERVAL

E
E
E
E

E
E
E
G
A
E
G
C
E
G

F
E
B

E
G
G

741

704
704
704
741

924

1365

1650

1479

1361
1027
1357
590
992
1432
260
564
1132
94

1209
924
826

1614

1448

1187
260
260

C.I.** REFERENCE

For coccidiosis plus mild respiratory and


enteric diseases
For coccidiosis plus mild respiratory and
enteric diseases

Repeat after 2 days

Repeat after 2 days for coccidiosis

Dosage based on pyrimethamine for


Leucocytozoon and Plasmodium
For sarcocystosis

Double dose for first day for coccidiosis


Juvenile dosage, repeat after 2 days

For coccidiosis
For coccidiosis and atoxoplasmosis
Loading dose 375 mg/L

For Pasteurella multocida and Hemophilus


gallinarum
For coccidiosis
For coccidiosis, do not deprive of water
coccidiosis

Precede with sulfamethazine injectable, give


dose in fish for malaria

Post-surgical wound care

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

1 g/L

0.15-.0.3 g/L
0.3 g/L
0.3 g/L

Passerine, Small
Pigeon
Pigeon

Sulfachlorpyridazine
Sulfachlorpyridazine
Sulfachlorpyridazine

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

318
C l i n i c a l Av i a n M e d i c i n e - Vo l u m e I

0.19-0.25 g/L
1 g/L
1 g/L
300 mg/kg food
300 mg/kg food

500 mg/kg food


0.17 g/L
0.25 g/kg
100
100
0.397 g/L
0.034 g/L
0.17 g/L

Budgerigar
Canary
Canary
Chicken
Passerine
Passerine, Small
Penguin, African

Pigeon
Pigeon
Pigeon

Pigeon
Pigeon
Pigeon
Pigeon

Poultry
Poultry
Raptor

Chicken

Poultry

Anseriformes
Chicken
Duck
Lory
Pigeon
Poultry
Raptor
Turkey

Sulfamethazine
Sulfamethazine
Sulfamethazine
Sulfamethazine
Sulfamethazine
Sulfamethazine
Sulfamethazine

Sulfamethazine
Sulfamethazine
Sulfamethazine

Sulfamethazine
Sulfamethazine
Sulfamethazine
Sulfamethazine

Sulfamethazine
Sulfamethazine
Sulfamethazine

Sulfanitran

Sulfanitran

Sulfaquinoxaline
Sulfaquinoxaline
Sulfaquinoxaline
Sulfaquinoxaline
Sulfaquinoxaline
Sulfaquinoxaline
Sulfaquinoxaline
Sulfaquinoxaline

Once
QD
Once
QD
QD
QD
QD
QD

QD

QD

QD
QD
QD

QD
QD
QD
QD

QD
QD
QD

QD
NL
QD
QD
QD
NL
BID

NL
QD

DOSAGE
INTERVAL

G
E
B
G
G
C
E
E

C
C
E

E
E
G
G

E
E
E

G
E
E
E
E
E
D

E
G

597
564
825
57
57
564
1612
564

564

564

564
564
1612

1240
1432
232
260

704
704
1240

57
1187
695
564
1437
1187
1614

1180
57

C.I.** REFERENCE

Repeat after 2 days


10-day slaughter withdrawal

10-day slaughter withdrawal


For Riemerella anatipestifer in ducklings

Add nitromide + roxarsone, 5-day slaughter


withdrawal, prophylactic
Add nitromide + roxarsone, nutritional use,
no slaughter withdrawal

Repeat after 2 days

Loading dose 375 mg/L, treat with B


vitamins for 5 days then repeat

For coccidiosis, perhaps Toxoplasmosis

Switch to sulfadiazine + sulfamerazine +


sulfamethazine when able to give orally for
malaria
Repeat 1 to 2 times at 2-day intervals
Repeat after 5 days
Wait 2 days then repeat for 3 treatment cycles
for coccidiosis, perhaps toxoplasmosis

12-day slaughter withdrawal

Use liquid formulation, wait 2 days then


repeat
Wait 2 days then repeat

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

Feed
Drink
Feed
PO
PO
Drink
Drink
Drink

Feed

Feed

PO
Drink
Drink

Drink
Drink
Drink
Drink

Drink
Drink
Drink

2 g/L
2 g/L
2 g/L

3.33-6.66 g/L
3.33-6.66 g/L
1.1 g/L
1.1 g/L

PO
Drink
Drink
Drink
Drink
Drink
IM

Drink
Drink

ROUTE

7
0.15 g/L
0.15 g/L
1 g/L
0.15 g/L
0.15 g/L
83-125

0.15 g/L
0.125 g/L

Avian
Avian

Sulfamethazine
Sulfamethazine

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

Chapter 9 | T H E R A P E U T I C A G E N T S

319

Topical

Drink

0.56 g/L

1 g/L
50
0.045 g/L
40
3g

Dilute solution

10-15

Poultry

Pigeon

Avian

Galliformes

Avian

Psittacine

Ramphastid

Avian

Sulfathiazole Sodium

Sulfatroxazole

Sulfonamide

Tamoxifen Citrate

Tannic Acid

Tannic Acid

Tea

Terbinafine

QD-BID

QD

q2w

PRN

NL

QD

BID

QD

q4d

QD

QD

QD

q4d

QD

QD

QD

QD

DOSAGE
INTERVAL

1668

1470

1446

1240

677

924

565

564

1479

1479

1479

1479

1479

1650

1650

1492

1492

C.I.** REFERENCE

May combine with itraconazole for systemic


mycosis

Prevent hemochromatosis by limiting iron


uptake, no citrus in diet

Add aspirin + ethyl alcohol to prepare 100


ml for fungal dermatitis
Add 3 g tannic acid + 3 g salicylic acid +
ethyl alcohol for 100 ml of solution for
dermatomycosis

Induce molting

Repeat after 2 days for coccidiosis

Add trimethoprim

Coccidial preventive

Repeat after 3 days, coccidiosis therapy

Coccidial preventive for replacement/breeder


8 to 12-week old broilers

Coccidial preventive for replacement/breeder


0 to 8-week old broilers

Coccidial preventive for market broilers

For coccidiosis

For coccidiosis

For coccidiosis

For coccidiosis

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

PO

Topical

NL

Drink

PO

Drink

Drink

Drink

Feed

Feed

Poultry

0.55 g/kg feed

Chicken

Feed

0.56 g/L

0.5 g/kg feed

Chicken

Drink

Poultry

0.1 g/L

Avian

Feed

Drink

Sulfaquinoxaline +
Diaveridine
Sulfaquinoxaline +
Diaveridine

0.1 g/kg food

Avian

0.33 g/kg feed

0.1 g/L

Avian

Feed

Chicken

0.1 g/kg feed

Avian

Sulfaquinoxaline +
Diaveridine
Sulfaquinoxaline +
Diaveridine
Sulfaquinoxaline +
Diaveridine
Sulfaquinoxaline +
Diaveridine
Sulfaquinoxaline +
Diaveridine
Sulfaquinoxaline +
Diaveridine

ROUTE

Sulfaquinoxaline +
Diaveridine

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

320
C l i n i c a l Av i a n M e d i c i n e - Vo l u m e I

10
8
2.5
8
250 IU

0.031-0.124 g/L
200-250
1.25 ml/L
30-60
0.04-0.12 g/L
55-110 mg/kg food
220 mg/kg food
0.549 g/L
50 mg TD
60
50
1 g/L soft food
220 mg/kg food
55-110 mg/kg food
550
100
250-500
200
100
250-500
5 g/kg food
44
100
100
44
100-200

Avian
Avian
Canary
Psittacine

Falcon, Saker

Avian
Avian
Avian
Galliformes
Pheasant
Pheasant
Pigeon
Pigeon
Pigeon
Poultry
Psittacine
Psittacine
Quail
Quail

Anseriformes
Avian
Avian
Avian
Avian
Avian
Chicken
Chicken
Crane
Falcon
Pigeon
Raptor

Testosterone
Testosterone
Testosterone
Testosterone Cypionate

Tetanus Antitoxin

Tetracycline
Tetracycline
Tetracycline
Tetracycline
Tetracycline
Tetracycline
Tetracycline
Tetracycline
Tetracycline
Tetracycline
Tetracycline
Tetracycline
Tetracycline
Tetracycline

Thiabendazole
Thiabendazole
Thiabendazole
Thiabendazole
Thiabendazole
Thiabendazole
Thiabendazole
Thiabendazole
Thiabendazole
Thiabendazole
Thiabendazole
Thiabendazole

NL
PO
PO
PO
PO
PO
Feed
PO
PO
PO
PO
PO

Drink
PO
Drink
Drink
Feed
Feed
Drink
Drink
PO
Drink
PO
Feed
Feed
Feed

IM

IM
IM
IM
IM

PO
Nebulize
PO

ROUTE

NL
QD
q2w
q10d
QD
q10d
QD
Once
QW-q2w
Once
Once
BID

NL
BID
NL
QD
QD
QD
QD
QD
QD
QD
TID
Once
QD
QD

QD

QW
QW
QW
QW

QD-BID
TID
QD

DOSAGE
INTERVAL

G
E
E
E
G
G
G
G
E
G
G
E

E
E
E
E
G
G
E
E
G
C
E
E
G
G

E
E
D
E

G
G
E

1325
111
111
924
1309
1309
1325
1325
1361
1325
1325
1400

111
111
741
704
678
678
704
1240
47
705
565
763
678
678

822

924
1473
1441
1240

1338
1743
1359

C.I.** REFERENCE

For thorny headed worms


For Syngamus
For ascarids
For Syngamus, Amidostomum
For Syngamus trachei
For ascarids
For ascarids, Capillaria and gapeworms
For Ascarids, Capillaria and gapeworms
For intestinal strongyles, ascarids
For ascarids, Capillaria and gapeworms
For Ascarids, Capillaria and gapeworms
Control of nematodes, may interfere with egg
laying

May add long-lasting oxytetracycline

50%, 2.5 g per teaspoon


For chlamydophilosis
Remove grit from diet during treatment

Loading dose of 125 IU each IV and IM in


lesion for localized tetanus

For baldness
Use with great care

For feather disorders

For mycosis
For respiratory aspergillosis
Prophylactic

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

10-15
1g/L aqueous
30

Avian
Parrot, Grey Congo
Raptor

Terbinafine
Terbinafine
Terbinafine

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

Chapter 9 | T H E R A P E U T I C A G E N T S

321

25 mg/kg fish
25
1-2
0.2 g/kg fish
1-2
1-2
100 g/L
1-3
1-3
1-2
2
0.2-0.25 g/kg fish
25
1
16.2
10-12.5
54
16.2
1 IU TD
0.1 U TD
1 U TD
1 U TD
1-2 IU/kg

25-50
1.08 mg/kcal
25
0.25 g/L
25-30

Anseriformes
Anseriformes
Avian
Bird, Piscivorous
Bird, Piscivorous
Crane
Duck

Eagle, Bald
Osprey
Raptor
Raptor
Raptor
Raptor
Raptor

Chicken
Chicken
Duck, Mallard
Turkey

Amazon Parrot

Cockatiel

Parrot, Grey

Pigeon

Psittacine

Avian
Avian
Avian
Chicken
Galliformes

Thiamine
Thiamine
Thiamine
Thiamine
Thiamine
Thiamine
Thiamine

Thiamine
Thiamine
Thiamine
Thiamine
Thiamine
Thiamine
Thiamine

Thiopental Sodium
Thiopental Sodium
Thiopental Sodium
Thiopental Sodium

Thyroid Stimulating
Hormone
Thyroid Stimulating
Hormone
Thyroid Stimulating
Hormone
Thyroid Stimulating
Hormone
Thyroid Stimulating
Hormone
PO
PO
PO
Drink
Drink

IM

IM

IM

IM

IM

IM
NL
PO
IM

NL
NL
PO
PO
Feed
IM
IM

Feed
Feed
IM-PO
Feed
PO
PO
Drink

NL
PO

ROUTE

QD
QD
QD
NL
QD

NL

Once

NL

Once

Once

PRN
PRN
PRN
PRN

QW
QW
QD
QW
QD
NL
NL

Once
QD
Once
QD
QD
QD
QD

NL
Once

DOSAGE
INTERVAL

E
E
E
B
E

B
B
B
B

E
E
E
E
E
E
E

E
G
E
E
E
E
E

G
G

565
1180
1492
857
704

1473

88

533

88

88

1080
1126
1095
1080

1188
1188
111
1068
1132
1433
1463

1190
46
1650
1554
1554
111
1358

418
1325

C.I.** REFERENCE

For mycoplasmosis
For Mycoplasma
Use 1/2 strength for prophylaxis

Add pentobarbital sodium

Add pentobarbital sodium

While feeding frozen fish


For fish diets

If eating frozen fish


If eating frozen fish

For stargazing and weight loss in ducklings

Supplement for fish eaters


For hypovitaminosis B1
For fish diet
For fish diet

For ascarids, Capillaria and gapeworms

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

Tiamulin
Tiamulin
Tiamulin
Tiamulin
Tiamulin

50
44

Ratite
Turkey

Thiabendazole
Thiabendazole

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

322
C l i n i c a l Av i a n M e d i c i n e - Vo l u m e I

5-10
2
15-20
20-22
2-3
30
2.64-25.2
50-75
5-10
15
2
2-3
5-10
22
6.6
2
6.6-8.8
2.7
15

Avian
Avian
Budgerigar
Budgerigar
Cassowary
Chicken
Cockatoo, G Sulfur-crested
Dove, Ring-necked
Duck
Eagle, Bald
Egret, Cattle
Emu
Emu
Flamingo
Flamingo, Chilean
Gannet
Goose, Lesser Magellan
Goose, White-fronted
Hawk

Hornbill, Rhinoceros
Ibis, Wood
Jabirus
Macaw, Scarlet
Osprey
Ostrich
Ostrich
Ostrich

Tiletamine + Zolazepam
Tiletamine + Zolazepam
Tiletamine + Zolazepam
Tiletamine + Zolazepam
Tiletamine + Zolazepam
Tiletamine + Zolazepam
Tiletamine + Zolazepam
Tiletamine + Zolazepam
Tiletamine + Zolazepam
Tiletamine + Zolazepam
Tiletamine + Zolazepam
Tiletamine + Zolazepam
Tiletamine + Zolazepam
Tiletamine + Zolazepam
Tiletamine + Zolazepam
Tiletamine + Zolazepam
Tiletamine + Zolazepam
Tiletamine + Zolazepam
Tiletamine + Zolazepam

Tiletamine + Zolazepam
Tiletamine + Zolazepam
Tiletamine + Zolazepam
Tiletamine + Zolazepam
Tiletamine + Zolazepam
Tiletamine + Zolazepam
Tiletamine + Zolazepam
Tiletamine + Zolazepam

IM
IM
IV
IM
IM
IM
IM
IM

IM
IV
IM
IM
IV
IM
IM
IM
IM
NL
IV
IV
IM
IM
IM
IV
IM
IM
NL

IV

IM-IV
IM-IV
IM
IM-IV
IM

Drink

ROUTE

PRN
PRN
PRN
PRN
PRN
PRN
PRN
PRN

PRN
PRN
PRN
PRN
PRN
Once
PRN
PRN
PRN
PRN
PRN
PRN
PRN
PRN
PRN
PRN
PRN
PRN
PRN

PRN

TID-QID
q2-4h
TID
BID-TID
BID-QID

QD

DOSAGE
INTERVAL

G
G
E
B
G
B
B
G

E
E
E
G
E
B
G
B
E
D
E
E
E
G
B
E
B
B
D

E
E
E
G
E

518
518
1617
1393
518
522
1393
481

1181, 1231
1617
243
518
1533
1737
518
1393
243
1401
1617
1533
1617
518
1393
1617
1393
1393
1401

1617

111
1180
1027
590
565

704

C.I.** REFERENCE

Add diazepam just prior to recovery for


captive animal

Chick dosage

Induction for gas anesthesia

May cause salivation and poor


immobilization

Induction for gas anesthesia

Induction for gas anesthesia

Supplement with 15 mg/kg ketamine


Induction for gas anesthesia

Good immobilization
Induction for gas anesthesia

Induction for gas anesthesia

Synergistic with aminoglycosides

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

28.7
11
2
4.4-11
9.26-17.6
5-20
4-5
5-10

150-200
5.1 mg/kcal
200
200
200

Avian
Avian
Raptors
Pigeon
Psittacine

Ticarcillin
Ticarcillin
Ticarcillin
Ticarcillin
Ticarcillin

Tiletamine + Zolazepam Albatross

0.225 g/L

Pigeon

Tiamulin

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

Chapter 9 | T H E R A P E U T I C A G E N T S

323

22-35
44
0.075 g/L
0.25-0.5 g/L
0.1-0.3 g/L
50
10
5
5 g/L
2.5-5
10
2.5-5
2.5-5
5-10
2.5-5
5-10

Parakeet, Ring-necked
Parrot, Patagonian
Partridge, Crested Wood
Pea Fowl
Pelican
Pheasant, Golden
Pigeon
Pigeon
Plover
Psittacine
Psittacine
Raptor
Ratite
Stork
Swan, Black

Teal, Blue-winged
Woodcock

Chicken
Chicken
Chicken
Avian

Avian
Avian
Avian
Crane
Parrot, Grey
Pheasant
Psittacine
Psittacine
Raptor
Raptor

Raptor

Tiletamine + Zolazepam
Tiletamine + Zolazepam
Tiletamine + Zolazepam
Tiletamine + Zolazepam
Tiletamine + Zolazepam
Tiletamine + Zolazepam
Tiletamine + Zolazepam
Tiletamine + Zolazepam
Tiletamine + Zolazepam
Tiletamine + Zolazepam
Tiletamine + Zolazepam
Tiletamine + Zolazepam
Tiletamine + Zolazepam
Tiletamine + Zolazepam
Tiletamine + Zolazepam

Tiletamine + Zolazepam
Tiletamine + Zolazepam

Tilmicosin
Tilmicosin
Tilmicosin
Tinidazole

Tobramycin
Tobramycin
Tobramycin
Tobramycin
Tobramycin
Tobramycin
Tobramycin
Tobramycin
Tobramycin
Tobramycin

Tobramycin

IM

IM
IM
Nebulize
IM
IM
IM
IM
IT
IM
IM-IV

Drink
Drink
Drink
PO

IM
IM

IM
IM
IM
IM
IV
IM
IM
IM
IM
NL
IM
IM
IM
IM
NL

NL

ROUTE

BID

BID-TID
BID-TID
TID
BID
TID
BID
BID
QD
BID
BID

NL
NL
NL
NL

PRN
PRN

PRN
PRN
PRN
PRN
PRN
PRN
PRN
Once
PRN
PRN
PRN
NL
PRN
NL
PRN

PRN

DOSAGE
INTERVAL

E
E
E
E
E
E
E
E
E
E

A
B
B
G

B
G

B
G
B
G
E
B
B
B
G
D
E
D
G
E
D

234

565
704
741
1473
741
1473
111
741
1240
1400

804
768
798
57

1393
518

1393
518
1393
518
1617
1393
1393
1737
518
1401
1240
1400
418
243
1401

1401

C.I.** REFERENCE

Add carbenicillin for pneumonia


For resistant Pseudomonas
Less nephrotoxic than other aminoglycosides

Possible polyuria

For sinusitis or airsacculitis

For Mycoplasma
For Mycoplasma

Supplement with ketamine PRN


Sedation
Supplement with 6.6 mg/kg ketamine PRN

Provides good immobilization

Induction for gas anesthesia

Supplement with 10 mg/kg ketamine PRN

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

10

26
11
10
11.3
2
16.6
40-60
30-60
17.6
10
5-10
10-20
2-5
2-5
6.6

10

Owl

Tiletamine + Zolazepam

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

324
C l i n i c a l Av i a n M e d i c i n e - Vo l u m e I

15
1
15
0.0125 g/L
7
0.15 g/L
0.090 mg/kcal
7-10
6
25
25
25
25
12.5
0.025 g/L
2 g/kg grain
0.025 g/L
125
125
100-158
125
40-44 g/L bait
1.5 g/L (0.15%)
5 g/L
5 g/L

0.048 g/L

Avian

Ostrich
Raptor

Anseriformes
Avian
Avian
Avian
Avian
Chicken

Chicken
Falcon
Kestrel, European
Kiwi
Mynah, Bali
Turkey

Bird, Seed-eater
Bird, Seed-eater
Booby
Cormorant
Duck, Mallard
Frigatebird, Magnificent
Turkey

Raptors

Avian
Avian

Anseriformes

Avian
Avian
Avian

Tolazoline HCl

Tolazoline HCl
Tolazoline HCl

Toltrazuril
Toltrazuril
Toltrazuril
Toltrazuril
Toltrazuril
Toltrazuril

Toltrazuril
Toltrazuril
Toltrazuril
Toltrazuril
Toltrazuril
Toltrazuril

Tribromoethanol
Tribromoethanol
Tribromoethanol
Tribromoethanol
Tribromoethanol
Tribromoethanol
Tribromoethanol

Trichlorfon

Tricide
Tricide

Trimethoprim + Sulfa

Trimethoprim + Sulfa
Trimethoprim + Sulfa
Trimethoprim + Sulfa

IM
IM
PO-SC

Drink

Topical
Flush

Topical

Feed
Feed
PO
PO
PO
PO
Feed

PO
PO
PO
PO
PO
Drink

Drink
PO
Drink
PO
PO
PO

IV
IV

IV

ROUTE

BID
QD
BID

QD

NL
NL

NL

Once
Once
PRN
PRN
PRN
PRN
Once

QD
QW
QD
Once
QD
QD

QD
QD
NL
QD
QD
QD

PRN
PRN

PRN

DOSAGE
INTERVAL

E
E
E

G
G

E
E
B
B
B
B
G

G
B
B
G
D
B

D
D
E
E
E
E

G
G

1434
1434
1483

1240

1278
1278

1408

4
4
1081
1081
1095
1081
1767

564
1134
1131
1223
1438
1025

1150
1221
1180
1180
1554
1479

481
201

1320

C.I.** REFERENCE

Emergency therapy

For nephritis, septicemia, hepatitis. For E.


coli, Pasteurella, Proteus, Salmonella, Listeria

Spray on wounds and dermatitis


Sinus flush, add antibiotic to solution,
potentiates antibiotics amikacin, neomycin,
enrofloxacin

Spray for mites

Add amylene hydrate


Corn is usual bait

Add amylene hydrate


Add amylene hydrate

Add chloralose

For Caryospora infestation


For Caryospora infection
For coccidiosis
For coccidiosis

Coccidiostatic
For coccidiosis
May repeat after 5 days for treatment and
control of Eimeria coccidiosis

For coccidiosis
Antiprotozoal

Reverse xylazine +detomidine +


medetomidine
Reverse xylazine

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

25
50
30-60

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

Chapter 9 | T H E R A P E U T I C A G E N T S

325

0.05-0.1 g/L
0.1 g/kg food
0.2 g/kg food
0.15-0.4 g/L
46-62
0.3-0.7 g/kg
15
0.2 g/L

Canary
Canary
Canary
Canary
Chicken

Goose

Ostrich
Passerine

Passerine

Penguin, African
Pigeon
Poultry
Poultry
Psittacine

Psittacine

Psittacine

Psittacine
Raptor

Raptor
Raptor
Raptor

Trimethoprim + Sulfa
Trimethoprim + Sulfa
Trimethoprim + Sulfa
Trimethoprim + Sulfa
Trimethoprim +
Sulfadiazine
Trimethoprim +
Sulfachlorpyridazine
Trimethoprim + Sulfa
Trimethoprim + Sulfa

Trimethoprim + Sulfa

Trimethoprim + Sulfa
Trimethoprim + Sulfa
Trimethoprim + Sulfa
Trimethoprim + Sulfa
Trimethoprim + Sulfa

Trimethoprim + Sulfa

Trimethoprim + Sulfa

Trimethoprim + Sulfa
Trimethoprim + Sulfa

Trimethoprim + Sulfa
Trimethoprim + Sulfa
Trimethoprim + Sulfa

PO
PO
PO

IM
SC

PO

IM

PO
PO
PO
Drink
PO

Feed

IM
Drink

Feed

Drink
Feed
Feed
Drink
Drink

PO
Drink
PO
Drink
IM
IM

ROUTE

BID
BID
QD

QD-BID
BID

BID-TID

BID

BID
QD
BID
QD
BID-TID

QD

QD
QD

Once

QD
QD
Once
NL
QD

BID
NL
BID
QD
BID
BID

DOSAGE
INTERVAL

E
E
G

G
E

G
E
G
G
E

G
E

E
E
E
E
A

G
E
E
E
E
E

1433
1400
94

1309
1240

1756

1240

128
704
585
585
1240

1437

401
1437

776

695
695
1187
1187
1023

1319
1180
1431
1431
1431
1240

C.I.** REFERENCE

Do not use on dehydrated birds


For coccidiosis, repeat after 2 days
Juvenile dosage

Use lower dosage for birds under 300 g for


bacterial nephritis
For respiratory and enteric infections
For nephritis, septicemia, hepatitis. For E.
coli, Pasteurella, Proteus, Salmonella, Listeria

For nephritis, septicemia, hepatitis. For E.


coli, Pasteurella, Proteus, Salmonella, Listeria

For nephritis, septicemia, hepatitis. For E.


coli, Pasteurella, Proteus, Salmonella, Listeria

Dosage based on trimethoprim, add drug to


food at the same time
Dosage based on trimethoprim, add drug to
drink at the same time

For Pasteurella multocida, trimethoprim to sulfa


ratio 1:5

Dosage based on trimethoprim


Dosage based on trimethoprim
Dosage based on trimethoprim only
Dosage based on trimethoprim only

Dosage based on trimethoprim


For coccidiosis
For coccidiosis
For coccidiosis
For nephritis, septicemia, hepatitis. For E.
coli, Pasteurella, Proteus, Salmonella, Listeria

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

20-50
60
17.5

52.8
30

16-100

110
120
55
0.3-0.5 g/L
20

0.2 g/kg

50-100
0.15-0.4 g/L
20-50
1 g/L
10
8-30

Avian
Avian
Avian
Avian
Avian
Bustard

Trimethoprim + Sulfa
Trimethoprim + Sulfa
Trimethoprim + Sulfa
Trimethoprim + Sulfa
Trimethoprim + Sulfa
Trimethoprim + Sulfa

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

326
C l i n i c a l Av i a n M e d i c i n e - Vo l u m e I

16-24
8
60

3 g/L

20-30
20
10 g/L
0.75 g/L
0.86 mg/kcal
1.08 mg/kcal
10 g/L saline
10 g/L saline
15

Psittacine

Psittacine

Pigeon

Raptor

Anseriformes
Anseriformes
Anseriformes
Avian
Avian
Avian
Avian
Avian
Avian

Avian
Avian

Avian

Bird, Aquatic
Bustard, Houbara
Canary
Canary
Chicken

Chicken

Cockatiel

Tubocurarine Cl

Tylosin
Tylosin
Tylosin
Tylosin
Tylosin
Tylosin
Tylosin
Tylosin
Tylosin

Tylosin
Tylosin

Tylosin

Tylosin
Tylosin
Tylosin
Tylosin
Tylosin

Tylosin

Tylosin

BID

BID

BID-TID

BID
BID
QD

DOSAGE
INTERVAL

QD

BID
TID
QD
Once
NL

BID

BID
TID-QID

TID
TID
QD
NL
TID-QID
QD
BID
BID
TID

Ophthalmic BID-TID

Drink

IM
IM
Drink
Feed
Drink

IM

IM
Nebulize

IM
PO
Flush
Drink
IM
PO
Flush
Nebulize
IM

Ophthalmic NL

PO

IM

PO

IM
IM
PO

ROUTE

E
G
E
E
A

E
E

D
D
D
E
E
E
E
E
E

G
G
A

111

1016

1503
932
695
1187
838

1650

1617
1650

1150
1150
1150
1180
1180
1180
1183
1185
1240

111

968

1473

1473

234
1308
968

C.I.** REFERENCE

For Mycoplasma gallisepticum , less effective


than danofloxacin
Add colistin for chronic respiratory disease
with E. coli
Mix powder with sterile water 1 to 10

Nasal or sinus
10 to 60 minutes
For birds > 1 kg for upper respiratory
infection for Mycoplasma, Pasteurella,
Chlamydophila
For Mycoplasma
Add dimethyl sulfoxide, adjunct to parenteral
therapy for air sacculitis
May use with lincomycin + spectinomycin
for mycoplasmosis
For Mycoplasma
For Mycoplasma

For mycoplasmosis
For mycoplasmosis
For mycoplasmosis, use 10 ml per bird

Every 5 minutes

For toxoplasmosis

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

Mix powder 1:10

0.25 g/L

10
20
0.25-0.4 g/L
0.4 g/kg food
0.5 g/L

10-40

10
10 g/L

50
30-50
60

Raptor
Ratite
Pigeon

Trimethoprim + Sulfa
Trimethoprim + Sulfa
Trimethoprim +
Sulfamethoxazole
Trimethoprim +
Sulfamethoxazole
Trimethoprim +
Sulfamethoxazole
Trimethoprim +
Sulfatroxazole

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

Chapter 9 | T H E R A P E U T I C A G E N T S

327

20-40
15-25
15
20
12.5 mg TD
50 mg TD
100-200 KIU/kg
20-600 KIU/kg
0.5 g/L
0.0004-0.0016

1 drop 4mg/ml soln

Crane
Emu
Falcon
Finch
Finch
Finch, House
Finch, House
Ostrich
Passerine
Passerine, Small
Pigeon
Pigeon
Pigeon
Pigeon
Pigeon
Psittacine

Psittacine

Psittacine
Quail
Raptor
Raptor
Rhea
Rhea

Hawk, Red-tailed
Pigeon

Chicken

Sparrow, House

Avian

Tylosin
Tylosin
Tylosin
Tylosin
Tylosin
Tylosin
Tylosin
Tylosin
Tylosin
Tylosin
Tylosin
Tylosin
Tylosin
Tylosin
Tylosin
Tylosin

Tylosin

Tylosin
Tylosin
Tylosin
Tylosin
Tylosin
Tylosin

Urate Oxidase
Urate Oxidase

Valnemulin

Vasotocin, Arginine

Vecuronium Bromide

PRN

QD

NL
NL

TID
TID-QID
QD
BID
Once
QD

NL

TID
TID-QID
TID
QD
QD
QD
QD
TID
QD
NL
QID
TID-QID
QD
QD
TID-QID
BID-TID

QD-TID

DOSAGE
INTERVAL

Ophthalmic q15min

IV

Drink

NL
NL

IM
IM
IM
IM
Parenteral
SC

IM

SC
IM
IM
Feed
Drink
Drink
Drink
PO
Drink
Drink
IM
IM
PO
Drink
IM
Ophthalmic

Topical

ROUTE

A
A

E
E
D
G
G
G

A
E
E
E
E
D
D
G
E
E
A
E
E
E
E
E

1233

1759

873

1761
1761

1240
1473
1612
234
582
582

763

596
1473
1027
1572
1572
1439
1439
467
1437
1187
847
111
704
704
1473
111

741

C.I.** REFERENCE

Dosage is dosage per minute, used for


antidiuresis

For Mycoplasma

Uricolytic
Uricolytic

Into distended sinus


Add penicillin G benzathine

For chronic air sacculitis

Initial Mycoplasma therapy, used in


combination with aminoglycosides

Mix powder with sterile water 1 to 10

Add drug to food at the same time

Add ciprofloxacin for mycoplasmosis


Preventive for mycoplasmosis

For Mycoplasma

Eye spray, powder 250 g/8.8 oz,


conjunctivitis, may use with tylosin in water

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

40

15
15-25
30
0.4 g/kg food
0.25-0.4 g/L
1 g/L
0.3 g/L
11.4
0.25-0.4 g/L
0.25-0.4 g/L
25
15-25
50
0.5 g/L
15-25
Mix powder 1:10

1:10 dilution water

Cockatiel

Tylosin

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

328
C l i n i c a l Av i a n M e d i c i n e - Vo l u m e I

60-120 ml/L

22 mg/kg food
20 KIU/kg
< 50 KIU/kg
< 20 KIU/kg

1
1-3
10

10-30

6.6 KIU/kg
40
0.05-0.1
0.1 KIU/kg oil fish
0.2-0.3 KIU/kg

Avian

Poultry

Amazon, Red Lored


Avian
Raptor

Amazon, Yellow-naped
Avian
Avian

Bird, Aquatic

Hawk, Red-tailed

Psittacine

Raptor

Avian

Avian
Avian
Bird, Aquatic
Ostrich

Vinegar, Apple Cider

Virginiamycin

Vitamin A
Vitamin A
Vitamin A

Vitamin B Complex
Vitamin B Complex
Vitamin B Complex

Vitamin B Complex

Vitamin B Complex

Vitamin B Complex

Vitamin B Complex

Vitamin D

Vitamin E
Vitamin E
Vitamin E
Vitamin E

PO

IM-SC

Parenteral
IM
IM

IM
NL
IM

Feed

Drink

NL
QW
Once
NL

Once

QW

q2d

Once

QW

NL
QW
NL

Once
Once
QW

QD

QD

QD
QD

E
E
E
G

G
E
E

G
E
E

D
E

924
1650
1478
93

58

1240

1240

1644

1503

1697
1470
1650

700
1481
1400

564

1487

1330
1205

1470

218

C.I.** REFERENCE

Juvenile dose

Antioxidant, metal toxicity


For hypovitaminosis E

Add calcium gluconate + oxytocin

Dosage based on thiamine, neuromuscular


disease, hepatic disorders, thiamineresponsive seizures
Dosage based on thiamine, stimulate appetite

Dosage based on thiamine


After hemorrhage with liver disease
Dosage based on thiamine for emergency
care
For debilitation, anemia, appetite stimulant,
neurological disorders
Dosage based on thiamine for debilitation

For clinical deficiency


For hypovitaminosis A and epithelial
regeneration (bumblefoot)

For dysbiosis, candidiasis, chronic bacterial


diarrhea, Gram negative infections, foul smell
feces

For low-grade candidiasis


For dysbiosis, Clostridium , GI tract bacteriosis

For lymphosarcoma - Check curent literature

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

IM-PO
Parenteral
Feed
IM

IM

IM

10-30 (thiamine dose) IM

10

10-30

15 ml/L
60-120 ml/L

Avian
Avian

Vinegar, Apple Cider


Vinegar, Apple Cider

Drink
Drink

IO

0.75 mg/m2 surface

Avian

Vincristine Sulfate

QW

Ophthalmic NL

0.8 g/L

DOSAGE
INTERVAL

Cockatoo

ROUTE

Vecuronium Bromide

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

Chapter 9 | T H E R A P E U T I C A G E N T S

329

1 mg Se, 25 mg E
0.05-0.1
4-100 KIU TD

0.2
0.2-2.2
0.2-2.5
0.025-2.5
0.2-2.5
0.2
0.25-0.5
36.3 KIU/kg
33 KIU Vit A/kg
33-66 KIU/kg

1-2
1-2 mg TD

Amazon, Red Lored


Avian
Ostrich
Raptor

Amazon, Yellow-naped
Avian
Avian
Avian
Avian
Lory, Chattering
Psittacine

Avian

Pigeon
Psittacine

Amazon Parrot
Amazon Parrot

Avian
Avian

Avian

Budgerigar
Cassowary

Cassowary

Cockatiel
Crane
Emu

Falcon

Vitamin E + Selenium
Vitamin E + Selenium
Vitamin E + Selenium
Vitamin E + Selenium

Vitamin K
Vitamin K
Vitamin K
Vitamin K
Vitamin K
Vitamin K
Vitamin K

Vitamins A, D, E

Vitamins A, D, E
Vitamins A, D, E

Xylazine HCl
Xylazine HCl

Xylazine HCl
Xylazine HCl

Xylazine HCl

Xylazine HCl
Xylazine HCl

Xylazine HCl

Xylazine HCl
Xylazine HCl
Xylazine HCl

Xylazine HCl

IM

IM
NL
IV

IM

IM
IV

IV

IM
IM

IM
IV

IM
IM

IM

Parenteral
IM
IM
NL
Parenteral
IM
IM

IM
IM
IM
SC

ROUTE

PRN

PRN
PRN
PRN

PRN

PRN
PRN

PRN

PRN
PRN

PRN
PRN

QW
QW

QW

NL
q4-8h
PRN
BID
NL
BID
q2d-QW

Once
q2w
QM
q3d

DOSAGE
INTERVAL

E
E
E

E
E

E
E

E
G

G
E

G
G
E
F
G
G
E

G
E
G
E

243

243
1189
1617

1617

243
1617

1431

704
1181

243
1609

590
1240

111

1697
87
1151
58
246
42
632

700
111
401
1240

C.I.** REFERENCE

Add ketamine, good for short surgical


procedures, must reverse
Add ketamine
Add ketamine, use yohimbine to shorten
recovery
Add ketamine, use yohimbine to shorten
recovery
Add ketamine
Add ketamine for anesthesia
Add ketamine, use yohimbine to shorten
recovery
Add ketamine

Add ketamine
Add ketamine, mix together in syringe, may
start with half dose
Add ketamine
Add ketamine, reverse with atipamezole,
prolonged recovery if not reversed

Give 33 KIU vitamin A + 3.3 KIU vitamin


D per kg
Dosage based on Vitamin A
For deficiencies, reproductive disorders and
bone healing

Neonate dosage

Follow with daily dose for 1 to 4 weeks


For hematochezia
Give every 2 to 3 weeks

0.05 mg selenium + 3.4 IU vitamin E total


dose for muscular weakness, capture
myopathy, deficiency

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

2.5
1
0.25

6.5
0.25

2.2

4
2.2

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

330
C l i n i c a l Av i a n M e d i c i n e - Vo l u m e I

0.28
N/A
1
0.1-0.2
0.1
0.125-1
0.11-0.27
0.2
0.2
1
0.15

Psittacine
Psittacine
Raptor
Raptor
Raptor

Raptor

Raptor

Ratite
Ratite
Ratite
Ratite
Stork
Swan (Black, Mute)

Swan, Mute

Avian

Avian
Avian
Avian
Avian
Budgerigar
Cassowary
Emu
Guinea Fowl
Guinea Fowl

Xylazine HCl
Xylazine HCl
Xylazine HCl
Xylazine HCl
Xylazine HCl

Xylazine HCl

Xylazine HCl

Xylazine HCl
Xylazine HCl
Xylazine HCl
Xylazine HCl
Xylazine HCl
Xylazine HCl

Xylazine HCl

Yeast Cell Derivatives

Yohimbine HCl
Yohimbine HCl
Yohimbine HCl
Yohimbine HCl
Yohimbine HCl
Yohimbine HCl
Yohimbine HCl
Yohimbine HCl
Yohimbine HCl

IO-IV
IV
NL
NL
IM
IV
IV
IV
NL

Topical

IV

IM
IM
IM
Parenteral
IM
IV

IV

IV

IM
IM
IV
IM
IM-IV

NL
IM
IM
IM
IM
IM-IV

ROUTE

PRN
PRN
PRN
PRN
Once
PRN
PRN
PRN
PRN

PRN

PRN

PRN
PRN
PRN
PRN
PRN
PRN

PRN

PRN

PRN
PRN
PRN
PRN
PRN

PRN
PRN
PRN
PRN
PRN
PRN

DOSAGE
INTERVAL

E
E
E
E
G
E
E
B
D

E
E
E
G
E
G

E
G
D
E
E

G
B
G
E
G
E

243
1181
1231
1481
83
1533
1617
553
1401

111

1190

4
4
243
418
243
1291

1174

1174

1573
201
1401
4
1240

1388
447
283
243
1481
1240

C.I.** REFERENCE

Antagonize ketamine/xylazine anesthesia

Shorten ketamine + xylazine anesthesia


To shorten xylazine recovery

Reverse xylazine
Reversal of xylazine
Reverse xylazine

Promote skin healing, Preparation H

Add ketamine

Add ketamine
Add acepromazine + etorphine
Add carfentanil
Add ketamine
Add butorphanol + ketamine for surgery
Use in combination with ketamine 1:3 or 1:5,
reverse with yohimbine
Sedation for small birds at high dosages
Sedation, small psittacine
Add ketamine
Add ketamine
Use in combination with ketamine 1:3 or 1:5,
reverse with yohimbine
Add ketamine for diurnal raptors, lasts 1
hour
Add ketamine, lower dosage regimen
produces less respiratory disturbance
Add ketamine
Immobilization
Add ketamine after 15 minutes
Heavy sedation
Sedation
Add ketamine, give 3/4 dose initially,
remainder if needed, gas anesthesia premed

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

2.2
1-2.2
0.5-1
1-2.2
0.2-0.4
2 mg TD

0.25-0.5

1-10
1-10
0.5
3
1-2.2

2.2
0.66
150 mg TD
1.5
10
1-2.2

Hawk
Ostrich
Ostrich
Parrot, Grey
Pigeon
Psittacine

Xylazine HCl
Xylazine HCl
Xylazine HCl
Xylazine HCl
Xylazine HCl
Xylazine HCl

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

Chapter 9 | T H E R A P E U T I C A G E N T S

331

0.125
12.5 mg TD
0.125
0.1-0.2
0.1-0.2
0.1
0.125
1 ml/kg
1.25-2.5 ml TD

12 mg TD
25

Ostrich
Ostrich
Ostrich
Psittacine
Raptor
Raptor
Ratite

Avian

Avian

Ostrich

Raptor

Yohimbine HCl
Yohimbine HCl
Yohimbine HCl
Yohimbine HCl
Yohimbine HCl
Yohimbine HCl
Yohimbine HCl

Yunnan Paiyao

Yunnan Paiyao

Zeranol

Zinc Methionine

PO

SC

PO

PO

NL
IV
IV
IV
IV
IV
IV

NL

ROUTE

QD

NL

BID

QD

PRN
PRN
PRN
PRN
PRN
PRN
PRN

PRN

DOSAGE
INTERVAL

D
G
G
E
E
G
G

1359

283

1112

1435

1401
283
481
1240
1240
201
418

1401

C.I.** REFERENCE

Antioxidant therapy, administer during lead


chelation therapy

Implant growth promotion

Mix with 3 (cockatiel) to 10 (macaw) ml


water, use 1 day pre-operative, also use as
topical flush

Stock solution 2 capsules per 15 ml lactulose

Reverse xylazine
Reverse xylazine
Reverse xylazine

Antagonist for xylazine

Antagonize ketamine/xylazine anesthesia

COMMENTS (see references for


duration, precautions and
contraindications)

**A = Pharmacokinetic research; B = Clinical efficacy trial; C = Manufacturers recommendation; D = Published with reference; E = Published without reference; F = Extrapolation from other species; G = Anecdotal

0.1

Hawk, Red-tailed

Yohimbine HCl

DOSAGE (mg/kg
unless otherwise
stated)

SPECIES

DRUG NAME

332
C l i n i c a l Av i a n M e d i c i n e - Vo l u m e I

Chapter 9 | T H E R A P E U T I C A G E N T S

333

Abbreviations
Abbreviation Translation

Abbreviation Translation

<

less than

IN

intranasal

>

greater than

indef

indefinite

>=

greater than or equal

IO

intraosseous

Bath

1 day or more in therapeutic liquid

IO-IP-IT-IV

BID

two times daily

intraosseous or intraperitoneal or intratracheal or


intravenous

BID-q2d

two times daily to every two days

IO-IP-IV-SC

intraosseous or intraperitoneal or intravenous or


subcutaneous

BID-QID

two to four times daily

BID-TID

two to three times daily

IO-IT-IV

intraosseous or intratracheal or intravenous

cm

square centimeter

IO-IV

intraosseous or intravenous

cm

cubic centimeter

IO-IV-SC

intraosseous or intravenous or subcutaneous

day

IP

intraperitoneal or intracoelomic or intrapleuroperitoneal

d>w

days to weeks

IP-IM

intraperitoneal or intramuscular

Dip

less than 1 day in therapeutic liquid

IP-IV

intraperitoneal or intravenous

doses

number of doses to give

IP-IV-PO

intraperitoneal or intravenous or by mouth

Drink

drinking water

IP-IV-SC

intraperitoneal or intravenous or subcutaneous

Epidural

epidural injection

IP-PO

intraperitoneal or by mouth

Feed

include in feed

IP-SC

intraperitoneal or subcutaneous

Flow

constant flow

IT

intratracheal

Flush

flush

IT-IV

intratracheal or intravenous

Fog

fog the environment

IT-IV-PO

intratracheal, intravenous and orally

gram

IU

International Units

ga

gauge

IUt

intrauterine

GI

gastrointestinal

IV

intravenous

gr

grain

IV-PO

intravenous or by mouth

hour

IV-PO-SC

intravenous or by mouth or subcutaneous

IA

intraarticular

IV-SC

intravenous or subcutaneous

IA-IM

intraarticular or intramuscular

kcal

kilocalories

ICa

intracardiac

kg

kilogram

ICa-IP-IV

intracardiac or intraperitoneal or intravenous

KHz

kilohertz

ICr

intracranial

KIU

thousand International Units

ID

intradermal

liter

IH

inhalation

life

lifelong therapy

IM

intramuscular

long

long therapy regimen

IM-IN-IO-IV

intramuscular or intranasal or intraosseous or


intravenous

month

square meter

intramuscular or intranasal or intravenous

cubic meter

intramuscular or intraosseous or intratracheal or


intravenous

MD

maximum dose

mEq

milliequivalent

IM-IO-IV

intramuscular or intraosseous or intravenous

mg

milligram

IM-IP

intramuscular or intraperitoneal

min

minute

IM-IP-IV

intramuscular or intraperitoneal or intravenous

MIU

million International Units

IM-IP-IV-SC

intramuscular or intravenous or intraperitoneal or


subcutaneous

ml

milliliter

mm

square millimeter

IM-IP-PO

intramuscular or intraperitoneal or by mouth

mmol

millimoles

IM-IP-PO-SC

intramuscular or intraperitoneal or by mouth or


subcutaneous

mol

molar solution

months

for several months

normal solution

nebulize

nebulization

NL

not listed

once

give single dose

intramuscular or intravenous or subcutaneous

ophthalmic

in the eye

intramuscular or by mouth

oz

ounce

IM-PO-SC

intramuscular or by mouth or subcutaneous

Parenteral-PO parenteral or by mouth

IM-SC

intramuscular or subcutaneous

PO

by mouth

intramuscular or topical

PO-SC

by mouth or subcutaneous

IM-IN-IV
IM-IO-IT-IV

IM-IP-SC

intramuscular or intraperitoneal or subcutaneous

IM-IV

intramuscular or intravenous

IM-IV-PO

intramuscular or intravenous or by mouth

IM-IV-PO-SC

intramuscular or intravenous or by mouth or


subcutaneous

IM-IV-SC
IM-PO

IM-Topical

PO-SC-Topical by mouth or subcutaneous or topical

334

C l i n i c a l Av i a n M e d i c i n e - Vo l u m e I

Abbreviation Translation

Abbreviation Translation

PO-Topical

by mouth or apply topically

q5h

every five hours

ppm

parts per million

q5min

every five minutes

ppt

parts per thousand

q60h

every sixty hours

PRN

as needed

q6d

every six days

q10-14d

every ten to fourteen days

q6m

every six months

q10d

every ten days

q6m-QA

every six months to every year

q1-2h

every one to two hours

q6w

every six weeks

q1-4h

every one to four hours

q7w

every seven weeks

q15min

every fifteen minutes

QA

every year

q2-3d

every two days to three days

QD

every day

q2-3h

every two to three hours

QD-BID

every day to two times daily

q2-3w

every two to three weeks

QD-q2d

every day or every two days

q2-4d

every two days to four days

QD-q3d

every day to every three days

q2-4h

every two to four hours

QD-QID

every day to four times daily

q2-4w

every two weeks to four weeks

QD-QW

every day to every week

q2-5d

every two days to five days

QD-TID

every day to three times daily

q2-6h

every two to six hours

QH

every hour

q2d

every two days

QID

four times daily

q2d-QW

every two days to every week

QM

every month

q2h

every two hours

QM-q2m

every month to every two months

q2m

every two months

qow

every other week

q2w

every two weeks

QS

add sufficient quantity

q30min

every thirty minutes

QW

every week

q33h

every thirty three hours

QW-q10d

every week to ten days

q3-4d

every three to four days

QW-q2w

ever week to every two weeks

q3-4h

every three to four hours

QW-q3w

every week to every three weeks

q3-4w

every three to four weeks

r10d

repeat in ten days

q3-5d

every three to five days

r2m

repeat in two months

q36h

every thirty six hours

r2w

repeat in two weeks

q3-6h

every three to six hours

r6m

repeat in six months

q3-6w

every three to six weeks

r7-10d

repeat in seven to ten days

q3-7d

every three to seven days

ra

repeat annually

q3-8h

every three to eight hours

rm

repeat in one month

q3d

every three days

rw

repeat in one week

q3d-q2w

every 3 days to two weeks

SC

subcutaneous

q3d-QW

every three days to every week

SCJ

subconjunctival

q3h

every three hours

SC-Topical

subcutaneous or topical

q3m

every three months

sec

second

q3w

every three weeks

short

short therapy regimen

q4-5d

every four to five days

slowly

administer slowly

q4-5h

every four to five hours

soln

solution

q4-6d

every four to six days

TD

total dose

q4-6h

every four to six hours

TID

three times daily

q4-6m

every four to six months

TID-q2d

three times daily to every two days

q4-6w

every four to six weeks

TID-QID

three to four times daily

q4-8h

every four to eight hours

topical

apply topically

q4d

every four days

vapor

vapor in enclosure

q4d-QW

every four days to weekly

vent

anus, rectum or cloaca

q4h

every four hours

week

q4m

every four months

weeks

for several weeks

q5d

every five days

year

q5d-QW

every five days to every week

microgram

Chapter 9 | T H E R A P E U T I C A G E N T S

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Chapter 9 | T H E R A P E U T I C A G E N T S

Emirates Falco, Newsletter


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Chapter 9 | T H E R A P E U T I C A G E N T S

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