Professional Documents
Culture Documents
Disclosure
Industry-sponsored
grants
Consultant
Research
Collaboration
Siemens
Novadaq Corp.
Veran Medical Technologies
Endobronchial Ultrasound
Radial
Central Airway
Peripheral Nodules
Convex-probe
EBUS-TBNA
endobronchial ultrasound
Endobronchial Ultrasound
Radial
Central Airway
Peripheral Nodules
Convex-probe
EBUS-TBNA
endobronchial ultrasound
Probe
BS20-26R
Balloon sheath
MAJ-643R
O.D.= 2.6mm
FBS
BF-ST30
Intracartilaginous
Subcarinal LN:
86% (EBUS) vs 74% (TBNA)
Other stations:
84% (EBUS) vs 58% (TBNA)
10
Endobronchial Ultrasound
Radial
Central Airway
Peripheral Nodules
Convex-probe
EBUS-TBNA
Olympus
Pentax
Fujifilm
11
endobronchial ultrasound
EU-ME1
EU-ME2
EU-C60
14
19 French
6.3mm Insertion Tube
2mm working channel
Color CCD video images
45 Forward Oblique
15
6.3mm
2.0mm
16
17
18
19
20
EBUS-TBNA
21
Pre-operative staging
Post-operative evaluation
Restaging
Dx
Mediastinal
22
23
Cost Effectiveness
A
24
EBUS Morphology
25
(g) homogeneous
(h) heterogeneous
26
Grade 0
Positive finding
Grade 1
Positive finding
Grade 2
Grade 3
BA inflow
p=0.033
Survival perioddays
Nakajima T, Yasufuku K et al. J Thorac Oncol. 2012; 7(6):1009-14
Harmonic Imaging
29
M-mode
Color-doppler
Elastgraphic Imaging
Contrast-agent Imaging
Evaluation of stiffness
EU-ME2
H-FLOW
Soft
30
Elastography
Hard
31
Malignant LN
32
Malignant LN
33
IHC
Direct sequence
Flow cytometry
RT-PCR
FISH
35
36
mRNA
Nakajima, Yasufuku et al Ann Thorac Surg. 2012; 94(6): 2097-101
miRNA
Lobectomy
38
Limited Resection
CALGB 140503
Surgery
Confirmation of NSCLC on Path
N0 status on frozen section
(4R, 7, 10R on right)
(5or6, 7, 10L on left)
Randomization
Lobectomy
39
Limited Resection
LN assessable by EBUS
2, 3p, 4, 7, 10, 11, (12, 8, 9)
LN not assessable
by EBUS
LN not assessable
by EBUS
N1 LNs
part of 12, 13, 14
Tracheobronchus
(mm)
(mm)
100
30
RUL bronchus
(mm)
170
150
80
20
60
10
110
40
90
130
(n=3)
Maximum reach
Endoscopic visibility range
Summary
46
Thank you
47