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Editorial
Editorial
impairment in specic cognitive domains could
have resulted in a lower threshold for impairment.
Limitations of the study include the relatively
short duration of the study (3 years), which raises
questions about the precision of the estimates of
MCI incidence. Due to greater attrition in the early
years of a study and the tendency of some mild
cases of MCI to revert to normal, estimates of
incidence are more stable over a longer duration of
follow-up. The recruitment of participants from
the clinical setting raises questions about the
potential for selection bias among subjects seeking
care; thus, the generalizability of the study ndings
may be limited to studies conducted in a similar
setting. Subjective memory complaints predicted
overall and non-amnestic MCI, but not amnestic
MCI as would have been presumed. This suggests
that subjective memory complaints may encompass
or herald impairment in certain non-memory
cognitive domains.
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Acknowledgement
Dr Rosebud O. Roberts is supported by the National Institutes of
Health (NIH) under project number: U01 AG06786, and by the
Robert H. and Clarice Smith and Abigail Van Buren Alzheimers
Disease Research Program. Dr Ronald C. Petersen is supported
by the National Institutes of Health (NIH) under project
numbers: P50 AG016574, AG006786, R01 AG011378, and
U01 AG024904.
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