Histology

BY
Dr Navneet Kumar
Professor Anatomy
KGMU LKO

-Bone
Histological features
Types of bone
-Cartilage
Histological features
Types of bone
Dr. Navnne Kumar Professor
Anatomy K G M U Lko
 Bone Histology
Bone membrane-
Periosteum
Endosteum
1.Cells- Osteoblast
- Osteocyte
- Osteoclast
2.Fibres(95%)-
Osteoclast
-collagen fibre Type1
3.Ground substance(5%)
-Calcium phosphate
85%
-calcium carbonate 10%
Dr. Navnne Kumar Professor
Osteocyte
Anatomy K G M U Lko
Dr. Navnne Kumar Professor
Anatomy K G M U Lko
Dr. Navnne Kumar Professor
Anatomy K G M U Lko
 Types of Bone

.Lamellar, Mature bone-

1. Compact bone
- circumferential lamellae
outer (periosteal)
Inner (endosteal)
- interstitial lamellae
- haversion system (osteon)
2. Spongy, Cancellous, Trabecular bone
- interstitial lamellae
.Woven, Immature,Primary bone-
- no lamellae
e.g fetal bone ,callus

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Anatomy K G M U Lko
 Compact bone
Lacuna have Osteocytes
Canaliculi contains the
cytoplasmic process of
Osteocytes
Haversian canal contains a
blood vessel
Circular arrangement of
osteocytes and fibres aruond
a blood vessel is an
osteon(Havesian canal
system)
Volkmann canal-
interconnecting haversian
canal
Bone marrow-central core
cavity of bone Dr. Navnne Kumar Professor
Anatomy K G M U Lko
Dr. Navnne Kumar Professor
Anatomy K G M U Lko
Dr. Navnne Kumar Professor
Anatomy K G M U Lko
Compact bone

Dr. Navnne Kumar Professor

Anatomy K G M U Lko
Dr. Navnne Kumar Professor
Anatomy K G M U Lko
Dr. Navnne Kumar Professor
Anatomy K G M U Lko
Dr. Navnne Kumar Professor
Anatomy K G M U Lko
 Spongy Bone

Branched bony
trabeculae
Encloses bone
marrow cavity
Cells and matrix
interstitial lamellae
type

Dr. Navnne Kumar Professor

Anatomy K G M U Lko
Dr. Navnne Kumar Professor
Anatomy K G M U Lko
Dr. Navnne Kumar Professor
Anatomy K G M U Lko
 Woven Bone

Random ,
interlacing
collagen fibres
Immature cells
are present

Dr. Navnne Kumar Professor

Anatomy K G M U Lko
 Cartilage
Perichondrium - may be present or absent
Cells - Chondrocytes
Matrix Fibres
. Collagen fibres
.Elastic fibres
- Ground substance
.Chondrotin sulphates
. Keratan sulphates
. Aggrecan,water electrolyte
Types- Hyaline cartilage
-Elasticcartilage (yellow fibrocartilage)
Dr. Navnne (white
-Fibrocartilage fibrocartilage)
Kumar Professor
Anatomy K G M U Lko
 Hyaline Cartilage

Perichondriun present
Chondrocytes in
lacunae as cell nests
(isogenous cell group)
Matrix is homogenous
contains collagen fibres
e.g-Costal,Articular
Tracheal, Thyroid,
Epiphysis

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Anatomy K G M U Lko
Dr. Navnne Kumar Professor
Anatomy K G M U Lko
Dr. Navnne Kumar Professor
Anatomy K G M U Lko
Dr. Navnne Kumar Professor
Anatomy K G M U Lko
 Elastic cartilage

Perichondriun present
Matrix filled with elastic
fibres
Elastic fibres are branched.
more at surface
Chondrocytes in lacunae
eg auricle, epiglottis

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Anatomy K G M U Lko
Dr. Navnne Kumar Professor
Anatomy K G M U Lko
Dr. Navnne Kumar Professor
Anatomy K G M U Lko
 Fibro cartilage

Perichondriun absent
Bundle of collagen fibres
Chondrocytes present in
rows
e.g-intervertivral disc
,glenoidal labrum

Dr. Navnne Kumar Professor

Anatomy K G M U Lko
Dr. Navnne Kumar Professor
Anatomy K G M U Lko