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NAME: AREA OF RESEARCH:
H. Rachel Lagiakos Medicinal/Organic
INSTITUTION AND LOCATION: Chemistry
Monash University, YEARS AS ACS MEMBER:
Cancer Therapeutics CRC, 5 years
Melbourne, Australia CAS SOLUTIONS USED:
JOB TITLE: SciFinder, PatentPak,
Senior Research Officer ChemZent
DESCRIPTION OF RESEARCH: I work in the field of cancer therapeutics, where we discover and
develop small molecule cancer drugs for emerging biological targets. My first project involved
the development of an inhibitor of a currently undrugged epigenetic target, PRMT5. This work
has led to a collaboration with a major pharmaceutical company to advance these potential
drugs. It really is a privilege to be involved in research that has the capability of changing lives!
JANUARY 2017
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DESCRIPTION OF RESEARCH: I design and develop new chromatographic materials for use in ion
chromatography and HPLC. The majority of my research is focused on new ion exchange phases
with unique selectivity. I also research new modes of analytical chemistry and am the primary
inventor of both high pH anion exchange chromatography of carbohydrates and accelerated
solvent extraction.
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DESCRIPTION OF RESEARCH: Our modern world depends on catalysis to form new materials,
pharmaceuticals, and polymers. Many of the complexes that we rely on contain expensive
transition metal elements. My goal is to discover cheaper main group compounds that can
facilitate these chemical transformations. My research involves synthesizing new, low-valent
main group species and using them to activate small molecules.
MAY 2017
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DESCRIPTION OF RESEARCH: I develop novel synthetic methods to access unusual highly reactive
molecules comprised of main group elements. These types of compounds enhance our
understanding of the fundamental aspects of chemical bonding.
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