Mansoura Faculty of medicine Medical Biochemistry Department

Quiz (3)
First year
(protein chemistry)
Student name: score :10
section: . Student number:.. Time : 10 min

I) Choose the best answer:

1- All of the following amino acids are neutral except:

a) glycine. b) threonine. c) lysine. d) proline. e) leucine.

2- The egg white protein, ovalbumin, is denatured in a hard-boiled egg. Which of

the following is least affected?
a) the primary structure of ovalbumin. b) the secondary structure of ovalbumin.
c) the tertiary structure of ovalbumin. d) the quaternary structure of ovalbumin.
e) none of these is affected.

3- Which of the following pairs of amino acids would carry a negative charge on
their side chain?
a) asparagine & Glutamine. b) leucine & glycine.
c) histidine & lysine. d) aspartate & glutamate.
e) serine & threonine.

4- All of the following is correct for the deamination of the amino acids except:
a) Oxidative deamination produces keto acid.
b) Reductive deamination produces fatty acid .
c) Hydrolytic deamination produces hydroxyl fatty acid.
d) Reductive deamination produces keto acid.

5- All of the following are simple proteins which are coagulated by heat:
a) Albumins, glutellins & globulin. b) glutellins, globulins & Histones.
c) prolamines, protamines & Histones. d) globulins, protamines & Histones.

I) Complete the following sentences:-

1- Main protein of milk is

2- Folloculation is ..

3- Strong bonds of proteins are . &

4- Essential hydroxy amino acid is ..

5- Secretory Ig is .
 Mansoura Faculty of medicine Medical Biochemistry Department
Quiz (3)
First year
(protein chemistry)
Student name: score :10
section: . Student number:.. Time : 10 min

Choose the best answer:

1- All of the uncharged polar amino acids are non essential except:
a) Serine. b) leucine. c) Threonine. d) Tyrosine. e) Lysine.

2. All of the following is true about the disulfide bonds except:

a) They are formed between 2 cystiene residues.
b) They are covalent bonds.
c) Responsible for the formation of helices of the protein.
d) Responsible for the - pleated sheets.

3. -alanine inter in the formation of:

a) Histones. b) Glutathione .c) pantothenic acid. d) Gelatin.

4. Which of the following is correct about charged amino acids?

a) charged amino acids has a fully ionized side chain at neutral pH.
b) charged amino acids include glutamic acid and serine.
c) all are hydrophobic amino acids.
d) all are essential amino acids.

5- Special arrangement of subunits of proteins that consists of more than one

polypeptide chain is referred to as:
a) primary structure of the protein. b) secondary structure of the protein.
c) tertiary structure of the protein. d) quaternary structure of the protein.

II) Complete the following sentences:-

1- Main protein of egg is

2- Coagulation is ..

3- Weak bonds of proteins are . &

4- Essential sulfur amino acid is ..

5- Immunoglobulin responsible for primary immune response is

 Mansoura Faculty of medicine Medical Biochemistry Department
Quiz (3)
First year
(protein chemistry)
Student name: score :10
section: . Student number:.. Time : 10 min

I) Choose the best answer:

1- Which of the following is a semi essential amino acid:

a) arginine. b) glycine. c) alanine d) valine. e) leucine.

2- The globular proteins is characterized by the following except:

a) the axial ratio is less than 10.
b) they include albumin and globulin.
c) they are less stable than fibrous proteins.
d) they include keratin and myosin.
e) is a shape of the tertiary structure of the protein.

3- Which of the following structures of protein is more stable:

a) primary structure: b) secondary structure:
c) tertiary structure: d) quaternary structure:

4- Considering the side-chains of the amino acids A) isoleucine B) proline C) Aspartic

which statement is TRUE ?
a) All are non-polar. b) Only (A) is polar. c) Only (C) is polar.
d) All are polar. e) All are acidic.

5- Proteins can be separated by the following methods except:

a) electrophoresis. b) chromatography. c) ultracentrifugation.
d) Coagulation. e) precipitation.

II) Complete the following sentences:-

1- Simple proteins of milk are & ..

2- IEP is ....

3- Primary structure of protein refere to .

4- Non essential hydroxy amino acid is

5- Ig with highest plasma concentration is .

 Mansoura Faculty of medicine Medical Biochemistry Department
Quiz (3)
First year
(protein chemistry)
Student name: score :10
section: . Student number:.. Time : 10 min

I) Choose the best answer:

1- The following amino acids are both glucogenic and ketogenic except:
a) phenylalanine. b) isoleucine. c) threonine. d) tyrosine. e) lysine.

2- Which of the following structures of protein is more stable:

a) Primary structure: b) secondary structure:
c) Tertiary structure: d) quaternary structure:

3- With regard to histones all is true except:

a) They are basic proteins
b) They are found in the cells associated with nucleic acid.
c) They are heat coagulable proteins.
d) They are soluble in water and diluted acids.

4- Glutathione is a:
a) metaprotein. b) proteose. c) Peptone. d) Peptide.

5- The following is correct when a sample of plasma protein is subjected to

electrophoresis:
a) Albumin will be the fastest in migration followed by globulin, globulin & globulin.
b) Albumin will be the fastest in migration followed by globulin, globulin & globulin.
c) Albumin will be the fastest in migration followed by globulin, globulin & globulin.
d) Albumin will be the fastest in migration followed by globulin, globulin & globulin.

II) Complete the following sentences:-

1- Acidic proteins are &

2- Indol group in .. amino acid is detected by test

3- Bonds of stabilizing pleated sheets are ... & .

4- Essential aromatic amino acids are &

5- Ig involved in allergic reaction is

 Mansoura Faculty of medicine Medical Biochemistry Department
Quiz (3)
First year
(protein chemistry)
Student name: score :10
section: . Student number:.. Time : 10 min

I) Choose the best answer:

1- Amino acids are amphoteric due to :

a) presence of an asymmetric carbon atom. b) presence of two groups (COOH and NH 2).
c) presence of the carbon skeleton. d) presence of nitrogen in their structure.

2- During denaturation of the protein which bonds are not broken:

a) hydrogen bonds. b) hydrophobic bonds.
c) electrostatic bonds. d) peptide and disulphide bonds.

3- All amino acids optically active except:

a) arginine b) proline. c) alanine. d) glycine.

4- The following is correct about proteins except:

a) albuminoids are proteins which are not soluble in most protein solvents.
b) protamines are water insoluble.
c) globulins are soluble in diluted salt solution.
d) glutelins are soluble in diluted acids and alkalies.
e) prolamines are soluble in 60-70% alcohol.

5- Glutathione is a tripeptide formed of the following three amino acids:

a) glutamic acid, cystiene and serine. b) aspartic acid, cystiene and serine.
c) glutamic acid, cystiene and glycine. d) glutamic acid, serine and glycine.

II) Complete the following sentences:-

1- Basic proteins are &

2- Zwitter ion is ..

3- Final shape of protein in tertiary structure may be . Or

.

4- Essential charged amino acids are & ....

5- Ig which give immunity to neonates is

 Mansoura Faculty of medicine Medical Biochemistry Department
Quiz (3)
First year
(protein chemistry)
Student name: score :10
section: . Student number:.. Time : 10 min

1- Choose the best answer:

1- All of the following reactions are due to the presence of amino group in the amino
acid except:
a) acetylation reactions. b) ester formation c) formal titration.
d) carbamino compounds formation. e) methylation reactions.

2- Special arrangement of subunits of proteins that consists of more than one

polypeptide chain is referred to as:
a) primary structure of the protein. b) secondary structure of the protein.
c) tertiary structure of the protein. d) quaternary structure of the protein.

3- During denaturation of the protein which bonds are not broken:

a) hydrogen bonds. b) hydrophobic bonds.
c) electrostatic bonds. d) peptide and disulphide bonds.

4- All of the following are conjugated proteins except:

a) mucins. b) FSH, LH and TSH. c) chylomicrons.
d) albumins & globulins. e) casienogen & ceruloplasmin.

5- Coagulation of the proteins is characterized by:

a) precipitation of denaturated protein at acidic pH.
b) irreversible by changing pH from I.E.P.
c) precipitation of denaturated protein at alkaline pH.
d) reversible by changing pH from acidic pH.
e) reversible by changing pH from I.E.P.

II) Complete the following sentences:-

1- Proteins rich in imino acids are & ..

2- Salting in means ..

3- Secondary protein derivatives are .

4- Acidic amino acids are & ..

5- Secretory Ig is .
 Mansoura Faculty of medicine Medical Biochemistry Department
Quiz (3)
First year
(protein chemistry)
Student name: score :10
section: . Student number:.. Time : 10 min

1- Choose the best answer:

1- Which of the following is non polar uncharged non essential amino acids?
a) alanine and glycine. b) leucine and proline c) leucine and glycine.
d) alanine and proline. e) alanine and Leucine

2- The quaternary structure of the protein is stabilized by:

a) hydrogen bonds and electrostatic bonds.
b) hydrophobic bonds disulphide.
c) electrostatic and hydrophobic bonds.
d) hydrophobic and disulphide bonds.
e) hydrogen bonds and disulphide bonds.

3- In denaturation of the protein disruption occur to:

a) Primary and secondary structure. b) Secondary and tertiary structure.
c) Secondary structure only. d) Tertiary structure only.
e) All of the above.

4- Examples of fibrous protein are:

a) Albumin and globulin. b) Myosin and keratin.
c) Albumin and protamine. d) Myosin and globulin.

5- All of the following are simple proteins which are soluble in water except:
a) Albumins. b) Histones. c) Protamines. d) Globulins.

II) Complete the following sentences:-

1- Protein rich in sulfur amino acids are ...

2- Salting out means ...

3- Primary protein derivatives are ...

4- Basic amino acids are .. & ..

5- Ig formed against soluble antigens is

 Mansoura Faculty of medicine Medical Biochemistry Department
Quiz (3)
First year
(protein chemistry)
Student name: score :10
section: . Student number:.. Time : 10 min

I) Choose the best answer:

1- Which of the following amino acids can form hydrogen bonds with their side(R) groups:
a) asparagine. b) aspartic acid. c) glutamine. d) serine. e) all of the above.

2- The globular proteins is characterized by the following except:

a) The axial ratio is less than 10.
b) They include albumin and globulin.
c) They are more stable than fibrous proteins.
d) Is a shape of the tertiary structure of the protein.

3- The tertiary structure of the protein is maintained by all the following except:
a) hydrogen bonds. b) Ionic bonds. c) disulphide bonds.
d) hydrophobic bonds (van der Waal forces). e) glycosidic bonds.

4- The type of amino acids present in human body is:

a) L- amino acids. b) D- amino acids. c) D- amino acids. d) L- amino acids.

5- All of the following are proteins which are not coagulated by heat except:
a) Albumins. b) Gelatin. c) caseinogens.
d) Alkaline meta proteins. e) Peptones.

II) Complete the following sentences:-

1- Examples of chromo proteins are & ..

2- Salting in means

3- Proteoses are ..

4- Branched chain amino acids are & .

5- Ig responsible for diagnosis of recent infection is .

 Mansoura Faculty of medicine Medical Biochemistry Department
Quiz (3)
First year
(protein chemistry)
Student name: score :10
section: . Student number:.. Time : 10 min

I) Choose the best answer:

1- An essential amino acid has one of the following characters :

a) Must be included in diet and cannot be formed in the body .
b) May be synthesized from metabolic intermediates, such as pyruvate.
c) There are only 4 essential amino acids in humans.
d) Essential amino acids can be stored.

2- Denaturation of the proteins results in:

a) Decrease solubility. b) Decrease viscosity.
c) Proteins can be crystallized. d) Destruction of the peptide bonds.
e) Protein become difficulty digested.

3- Folloculation of the proteins is characterized by:

a) Precipitation of denaturated protein at acidic pH.
b) Irreversible by changing pH from I.E.P.
c) Precipitation of denaturated protein at alkaline pH.
d) Reversible by changing pH from acidic pH.
e) Reversible by changing pH from I.E.P.

4- All of the following are simple proteins which are insoluble in water except:
a) albumins. b) glutellins. c) prolamines. d) globulins. d) albuminoids.

5- By placing a hydroxyl group on the phenyl ring of phenylalanine which amino

acid would be formed:
a) threonine b) histidine c) tyrosine d) serine e) hydroxyproline

II) Complete the following sentences:-

1- Globin is rich in .... & .... amino acids

2- Tripeptide contain peptide bonds.

3- All amino acids contain amino and carboxyl groups except & ..

4- Hydrogen bonds are formed when .. occurs between .....

5- Ig involved in hypersensitivity reactions is .