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Lipids are heterogenous group of compounds related to fatty acis either actual or
potential and are insoluble in water though soluble in other solvents like ether
,chloroform and benzene and chemically are esters of fatty acid and some alcohols.
High level of progesterone inhibits secretion of FSH and LH hence no new egg
follicles are developed and hence no ovulation occur. E.g triple :Tri-cyclen contains
norgestimate which mimics progesterone and ethynyl estradiol which mimics
estrogen .
The triple bond ethyne group on steroids allow for oral administration.
Implants contains levonorgestrel hormone similar to progestrerone made by
ovaries ,
Levonogestrel keep sperm from entering the uterus by thickening the cervical
mucus and thinning lining of uterus.
When sugars cannot be used as cellular fuel ,more fats are mobilized resulting in
high fatty acid level in blood. (lipidemia) . in severe cases of diabetes mellitus ,blood
level of fatty acids and their metabolites rise. The fatty acid metabolites collectively
known as ketone bodies are organic acids and when the accumulate in blood ,the
blood ph drops resulting in Ketoacidosis ,severe ketoacidosis is life
threatening.If untreated it disrupts the heart ctivity and oxygen transport and
severe depression of the nervous system leads to coma and death.
Fat soluble vitamins A,D,E,K bind to ingested lipids and are absorbed along with
their digestion products. Anything that interferes with fat absorption also interferes
with the uptake of fat soluble vitamins.
Steroid hormones from cholesterol i.e adrenorcorticoids(corticosteroids
,corticoids) :