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Administration Monitoring
Once daily as an intravenous infusion in 100mls A post-dose level is required. Obtain a single
of Dextrose 5% or Sodium Chloride 0.9% over 60 serum sample 12 to 18 hours after the dose.
minutes.
based onEvening administration
ideal body recommended.
weight (IBW) Send
rather than actual sample
body weightto (ABW)
CHEMICAL PATHOLOGY.
as tobramycin distributes
poorly in fat. Exclusions Blood sample forms must include:
Once daily gentamicin is inappropriate and
Date and time of drug administration
should not be used in:
Date and time of blood sampling
Endocarditis Ascites Dose per kg used (e.g. 5mg/kg)
Pregnancy Osteomyelitis Dosing regime (e.g. daily dosing)
Major burns Myeloma patients
Target serum gentamicin level:
Caution in renal impairment (GFR <30): 12 hours post dose = <2mg/L
See full policy on intranet for dosing guidelines in 18 hours post dose = <1mg/L
renal impairment.
For further advice please contact MICROBIOLOGY CGH ext. 4430, GRH ext. 5052
Full version of Once Daily Gentamicin Administration and Monitoring Policy is available on the intranet.