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Select the alternative A, B, C or D that best answers the question. Fill in the response oval
completely.
A B C D
If you think you have made a mistake, put a cross through the incorrect answer and fill in the new
answer.
A B C D
If you change your mind and have crossed out what you consider to be the correct answer, then
indicate the correct answer by writing the word correct and drawing an arrow as follows.
correct
A B C D
1 What is homeostasis?
(A) Mitosis
(B) Cell differentiation
(C) Genes
(D) Mutation
4 What is the name of the blood vessel shown in the diagram below?
(A) Capillary
(B) Artery
(C) Vein
(D) Valve
5 Haemophilia is a blood disorder controlled by a recessive sex-linked gene. An unaffected
daughter, whose father had haemophilia, married an unaffected male. What is the
probability that the daughter born from this marriage has haemophilia?
(A) 0%
(B) 25%
(C) 50%
(D) 75%
2900 m
(A) Bacteria
(B) Fungi
(C) Macro-parasite
(D) Protozoan
8 Which of the following involves an organism containing a foreign gene, often from
another species?
Ureter
Cortex
Renal artery
Which part is responsible for the transport of waste to the bladder for excretion?
11 Which of the following tables correctly shows the urine concentration of mammals,
marine fish and freshwater fish?
Which pair of scientists conducted a similar experiment to the one the student conducted?
1) Detecting changes from the stable state In this stage a receptor of some kind
detects a change in a specific variable from the desired level of the variable. The
information that there has been an undesirable change is then transmitted to the next
part of the control system
Air conditioner
Thermometer Temperature
Thermostat
Thermometer Temperature
Heater
Question 18 (3 marks)
When mammals breathe they consume oxygen from the air and release carbon dioxide into
the air. Explain why this process is essential for survival. 3
Oxygen from the air is a major reactant in respiration. Respiration in cells produce
the energy needed to support the cells enzyme and metabolic activity and hence has
a crucial role in maintaining the mammals survival. It is thus essential that there are
enough reactants supplied through oxygen consumption in the air in order to provide
enough energy for cells to keep the mammal alive
Carbon dioxide is a major product in respiration. Since water is prevalent within the
internal structure of the mammal, any carbon dioxide present will dissolve in water
forming carbonic acid, thus lowering the pH of the system. If carbon dioxide is not
removed, then the accumulation of carbonic acid will change the optimal conditions of the
system, thus affecting enzyme activity to a point where it they may be unable to support
bodily processes that are essential for maintaining life. This is why removal of carbon
dioxide by releasing it into the air is essential for survival as it minimises changes in
optimal enzyme activity needed to support life
Question 19 (6 marks) Marks
In cases where there is a large volume of blood lost from a patient, there is usually the need
for a blood transfusion from an appropriate donor, often in the form of extracted products.
(b) Assess the probability that patients who require extract transfusions will receive them. 2
Since there are many restrictions imposed on the type of person who is
allowed to give blood to minimise transplant infection as well as the low
number of eligible people who choose to donate blood, the supply of blood
extracts is fairly low
Therefore, due to the limited supply of donated blood, the probability that
patients will receive extract transfusions when they require them, is fairly low,
particularly if the demand is high such as in situations of crisis
Research into artificial blood involves synthesising chemicals which can act as
substitutes to the actual extracts of blood. Should this research be successful then
artificial blood can act as an alternative to donated blood. This may have massive
implications on society
There are currently restrictions on the type of person who can donate blood for
safety reasons. Artificial blood can overcome this obstacle easily, given that is
stored appropriately. This means that unlike donated blood, it is not exposed to a
lot of risky inputs such as drugs or pathogens that may cause infection. Thus
artificial blood can act as an effective alternative to donated blood
Also, artificial blood can potentially solve the problem of low donor numbers
since it can be mass produced with the synthesis of certain chemicals available.
Hence patients who require extract transfusions will have a higher probability of
actually receiving them through artificial blood. This shows that artificial blood
can potentially be an effective alternative to donated blood
Since there are many advantages of the use of artificial blood over donated blood,
successful research into artificial blood will have massive positive implications
on society as more lives can be saved if the research is successful
Question 20 (3 marks) Marks
Explain why active transport is essential in the removal of nitrogenous wastes in organisms 3
In the table below, compare the process of renal dialysis and the functions of the kidney 2
Blood is also an essential medium for the removal of wastes. For example carbon
dioxide is a waste product of cell respiration and must be removed. If it is left to
accumulate in the body system, it will dissolve in water, forming carbonic acid
which results in lowered pH. This leads to the distortion of internal conditions
and may decrease enzyme activity and consequently lower metabolic efficiency
in bodily processes. Therefore, the waste must be removed. Blood is an effective
medium which allows this removal. Cells can release their waste products into
blood, which is then removed either as nitrogenous wastes through the urinary
system or carbon dioxide through the respiratory system
Furthermore, blood is an essential medium for white blood cells in the immune
response. If an organism is infected by pathogens (or antigens), blood becomes
an efficient medium in transporting lymphocytes to the region of the pathogens
such that they can be chemically destroyed to minimise disease. Without blood,
the efficiency and effectiveness of the immune response cannot occur and the
organism is at a very high risk of getting infected and killed. Therefore blood is
essential in minimising disease for an organism
The introduction of the cane toad in Australia led to the alteration of the red bellied
black snakes head size over time. If a snake consumes a cane toads, toxins are
released by the cane toad that can kill the snake
However snakes with a larger ratio of body length to head size seemed to be least
affected by the presence of the cane toad. Snakes with smaller heads were limited to
consuming smaller and younger cane toads whose toxins are not as lethal compared
to those found in more developed and larger adult cane toads
This meant that the snakes with smaller heads were naturally selected to be desirable
to such environmental changes and hence had a higher success rate of reproduction
than those with larger heads. This meant that the species of the red bellied black
snake eventually changed with smaller heads due to the introduction of the cane toad
Question 24 (3 marks)
Co-dominance is seen in the coat colour of the shorthorn cattle. These animals have an allele
for red fur and an allele white fur. As neither is dominant, cattle with both heterozygous
alleles have a mixture of red and white fur known as roan.
Draw a Punnett square to represent the co-dominance with a cross between two different 3
homozygous parents.
R R
KEY:
1
Question 25 (4 marks) Marks
A particular disease is hereditary and is not sex-linked.
The pedigree below represents a family in which some members have the disease.
Explain why it may be difficult to determine whether the disease is dominant or recessive.
4
Case 1 - Assume the disease allele was dominant (let this be R)
The phenotype for individual 1 must be rr and for affected individual 2 it must be
heterozygous Rr such that their offspring can either have at least one dominant allele R
or both recessive alleles rr
Individual 3 must have phenotype rr hence the offspring produced with the second child
of the 1st generation parents must be homozygous recessive (rr), which is true according
to the pedigree (rr with rr gives any offspring rr)
The phenotype of the first child from the 1st generation parents is rr and his partner has at
least one dominant allele R, which allows for the possibility of offspring with one
dominant allele and hence be affected by the disease
Given that either case holds true for the pedigree, it is difficult to conclusively determine
whether the allele for the disease is dominant or recessive without extra information
Note that we do not take into account the ratios of affected and unaffected offspring
because the probability of a certain phenotype when producing one offspring is
independent of other offspring
Question 26 (3 marks) Marks
From the diagram above, select ONE pair of scientists and explain how they contributed to
the understanding of genetics 3
James Watson and Francis Crick suggested the double helix structure of DNA with
two phosphate-sugar strands winding around the outside nitrogenous bases with the
pairs adenine to thymine and guanine to cytosine. Their structure was bases on the X-
Ray diffraction photographs of DNA taken by Rosalind Franklin. From that data,
they constructed a three dimensional model of DNA which was presented to the
scientific public and this won them the Nobel Prize in 1962
Question 27 (3 marks)
This allowed the black moths to reproduce and pass on their desirable characteristics
to their offspring whereas the decline in white moths decreased their levels of
reproduction. This led to the current predominance of the black peppered moths
Question 28 (5 marks) Marks
There is a significant relationship between DNA and polypeptides.
Transcription
Translation
tRNA anticodons
(b) Explain how mutations in DNA can lead to the generation of new alleles. 3
Mutations are the changes in the DNA sequence caused by some mutagen
When changes in the sequence of a DNA strand occur, this results in a change in the
sequence of the complementary mRNA molecule via transcription
This causes different biochemical processes and reactions to occur, and hence may
affect the type of alleles that are a determinant in an organisms phenotype
Therefore, due to the close relationship between DNA and alleles via the polypeptide
synthesis process, any mutations in DNA can lead to the generation of new alleles
Question 29 (7 marks) Marks
With reference to examples, evaluate the impact of current reproductive technologies on the
path of evolution. 7
Cloning is the process of creating an exact copy of an organism. A donor egg has
its nucleus replaced by a nucleus from a cell of the organism to be cloned. An
electrical stimulus is used to fuse the nucleus with the egg cell and to stimulate
cell division. When it reaches embryo stages, it is introduced into a surrogate
mother where it continues development. When born, it is genetically identical to
the animal that donated the nucleus
Cloning will heavily alter the evolution path of a species because there will exist
both major selective pressures of humans and of the environment, whereas
without cloning, it would only be the environment. Cloning is controlled by
humans and there are characteristics in the clone that are desired by humans
which permit the clones survival. Producing an exact copy of an organism limits
genetic diversity within a species thus decreasing the chances of having an
advantageous mutation to initiate natural selection. Therefore, natural selection
rate is decreased as human selective pressures work against the progress of
selective pressures of the environment and this significantly alters the species
future evolution path as reproduction continues to later generations
Four agar plates were prepared. Precautions were taken by cleaning the bench with
ethanol and having Bunsen Burners sterilising the air as well as wearing gloves to
prevent other micro-organisms from disrupting the experiment with inaccuracies
One agar plate was left closed and sealed with tape, which was the control. Another
plate was opened and exposed to the air for about one minute and then sealed with
tape. One other plate was opened at 45 degrees and was given a sample of water
from an organic environment before being sealed with tape. The other plate was
opened at 45 degrees and smeared with yoghurt before being sealed with tape
The plates were left in an incubator for a week and observations were made on the
plates in reference to a textbook to identify microbes seen on the plate
Question 31 (4 marks)
Malaria is a disease that has affected many throughout history. Outline the historical
development in understanding the cause and prevention of malaria. 4
Once the source of malaria was established, a preventative measure was developed.
Swamps were drained to minimise mosquito breeding grounds. Paul Hermann Muller
discovered the insecticidal properties of DDT and this allowed the control of
mosquito populations hence minimising the spread of malaria
Question 32 (2 marks) Marks
Inflammation Phagocytosis
From the diagram above, choose ONE defence mechanism and describe how it functions in
preventing pathogen infection. 2
This allows white blood cells to leave the blood vessels and move into the damaged
tissue to attack the pathogen that has entered the system. Also, the heat aids in killing
the pathogen or limiting its spread by attempting to denature its enzymes. This helps
prevent the pathogen from infecting the host
Question 33 (4 marks)
Explain how B cells and T cells contribute to the human bodys immune response. 4
The human bodys immune response involves the interaction between B and T
lymphocytes each of which attempt to eliminate the pathogen from the body
Each B cell has a unique receptor protein which binds to a particular antigen. When a
pathogen enters the bloodstream its antigen may bind to a particular receptor of a
certain B cell. Phagocytosis occurs which attract T helper cells to stimulate this B cell
via interleukins to divide rapidly into several plasma cells. The plasma cells produce
antibodies which react with antigens of pathogen hence depleting the pathogen
Killer T cells recognise the antigen from the B cell, then track down and bind with an
infected cell and insert a toxin called perforin which ruptures the pathogen membrane.
As the immune response concludes, Suppressor T cells prevent the production of more
plasma cells and antibodies to maintain the balance of the immune system
Memory B and T cells are also produced in the immune response. These remain in the
body after immune response and reactivate quickly if the same antigen infects the
body again. This ensures a quicker secondary immune response
Question 34 (4 marks) Marks
In your Biology course you have been required to gather and analyse information on a non-
infectious disease.
Feature Description
a) Construct the most appropriate graph for the information in the table on the grid
provided below. 4
Incidence rate of melanoma in NSW 1993 - 2002
70
60 Key:
50
Males
40
Females
30
20
10
0
1993 1994 1995 1996 1997 1998 1999 2000 2001 2002
Year
b) Clarify why it may be difficult to extrapolate information about the possible
1
incidence of melanoma in the year 2007 from the graph you have drawn.
There are too many fluctuations of increases and decreases and no obvious trend, so
it is therefore difficult to predict the possible incidence of melanoma in future years
such as 2007 according to the graph
Question 36 (7 marks) Marks
Prevention is better than cure
The statement is true as prevention of a disease has proved to be far more effective
than the cure for the same disease
Whilst the development for cures for diseases was successful in the past, they are no
longer as successful in modern society
For example, antibiotics were extremely successful when they were developed for
the world wars as they directly depleted the cell membrane of bacteria that caused
the disease. This served as an extremely beneficial means of helping wounded and
infected soldiers in war recover. However, due to the extensive use of antibiotics,
natural selection allowed bacteria to develop mutations that led them to being
unaffected by antibiotics. When these bacteria reproduced, their anti-biotic resistant
genes became abundant as those without the gene were eventually killed by
antibiotics. This led to the rise of resistant strains in which antibiotics were no longer
effective against. It is clear that the common antibiotic did not prove to be successful
in the long term. Thus, a cure for a disease is not very effective in helping to
remove pathogens from causing disease
On the other hand, preventions such as vaccines and public health programs have
proved to be far more successful, particularly for non-infectious diseases which have
few known cures. It is also more economically efficient because there is not as much
extensive research involved in preventing diseases compared to finding cures
Public health programs are aimed to educate people about risk factors and promote
awareness of diseases. For example the Slip, Slop, Slap campaign was aimed at
making people aware of the risk factors which can lead to skin cancer. It was
effective as it promoted simple preventative measures, such as putting on sunscreen
and a hat, from an otherwise incurable disease and it does not require billions of
dollars of research in hope of finding a cure to eradicate the cancer
The above evidence clearly shows that prevention has proved far more successful
than a cure, thus it is undoubtedly true that prevention is better than cure
End of paper
Multiple Choice Answer Sheet
1. A B C D
2. A B C D
3. A B C D
4. A B C D
5. A B C D
6. A B C D
7. A B C D
8. A B C D
9. A B C D
10. A B C D
11. A B C D
12. A B C D
13. A B C D
14. A B C D
15. A B C D