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Suppurative Complications:
Tonsillopharyngitis pharyngeal cellulitis or Abscess
Otitis Media
Sinusitis
Necrrotizing Fasciitis
Others
Treatment
Penicillin V Drug of choice for streptococcal pharyngitis
Cephalosporins/ Macrolides alternative for patients allergic to Penicillin
Prevention
Vaccination
There is no vaccine against GAS available for clinical use, although
development of this preventive measure is under investigation. An important
area of uncertainty is whether vaccine-induced antibodies may cross-react with
host tissue to produce nonsuppurative sequelae in the absence of clinical
infection.
Foodborne Illness
Streptococcal contamination of food has been implicated in foodborne
outbreaks of pharyngitis, and foodborne transmission of GAS pharyngitis by
asymptomatic food service workers with nasopharyngeal carriage has been
reported. Factors that can reduce foodborne transmission of GAS pharyngitis
include thorough cooking, complete reheating, and use of gloves while handling
food.
Prophylaxis
Continuous antimicrobial prophylaxis is only appropriate for prevention of
recurrent rheumatic fever in patients who have experienced a previous episode
of rheumatic fever.
Prognosis
For all types of pharyngitis, the prognosis is excellent. Streptococcal pharyngitis has a
5- to 7-day course, and symptoms usually resolve spontaneously, without treatment
though in rare cases, rheumatic fever can develop if GABHS is left untreated.
Pathophysiology
Ingestion of food with
microorganism
Airborne Droplets
Tonsil/Pharynx
Lymphocytes IgM
Inflammatory Process
Reset Hypothalamus
Regulator
Fever Loss of
Appetite
Malaise