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C 1. This is obtained from an examination of the tissues and organs of the dead.
a. Experimental evidence c. post-mortem evidence
b. Chemical evidence d. circumstantial evidence
C 2. Death may result from poisoning due to the following causes, except:
a. due to interference with the carriage of oxygen
b. due to inhibition of the respiratory movements by neuro muscular agents
c. due to interference with the enzyme system utilizing it
d. circulatory failure as a result of cardiac glucosides
B 3. The most serious potential consequence of ingestion of liquid hydrocarbon such as kerosene or gasoline is:
a. paralysis of the peristaltic motion of the GI tract
b. the aspiration of the poison into the respiratory tract
c. destruction of body enzymes by the poison
B 4. The specific antidote for the treatment of poisoning due to oral ingestion of silver nitrate would be the oral
administration of :
a. acetic acid solution c. sodium bicarbonate
b. normal saline
B 7. A poison which increases suddenly in its intensity of action after slow or gradual addition of it is
a. corrosive poison c. true poison
b. cumulative poison d. irritant poison
A 11. The evidences to be saved in nonfatal poisoning are the following, except:
a. lung d. blood
b. urine e. body fat
c. food
B 12. A specialized field of toxicology that designates an area of professional emphasis within the realm of medical
science.
a. Forensic toxicology c. Environmental toxicology
b. Clinical toxicology d. Regulatory toxicology
C 13. This is an area of toxicology which is concerned directly with toxicity testing, which provides necessary information
for safety evaluation and regulatory requirements.
a. mechanistic toxicology c. descriptive toxicology
b. regulatory toxicology d. forensic toxicology
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D 16. When reporting cases of poisoning like eating in a public restaurant, the cases should be reported to the:
a. nurse d. public health officer
b. family doctor e. BFAD
c. pharmacist
C 22. The percentage of oxygen which is indicated for carbon dioxide poisoning to increase the conversion of
carboxyhemoglobin to hemoglobin and myoglobin and to increase oxygen saturation of the plasma is:
a. 50% c. 100%
b. 75% d. 10%
C 24. Convulsions caused by drug poisoning are most commonly associated with:
a. Phenobarbital c. strychnine
b. diazepam d. chlorpromazine
A 25. Alkanizing the urine with sodium bicarbonate is useful in the treatment of poisoning with:
a. ASA and barbiturates c. amphetamines
b. phencyclidine d. morphine
D 26. Activated charcoal may be used in the treatment of these poisoning, except
a. Phenobarbital c. aspirin
b. propoxyphene d. methanol
D 27. These statements regarding carbon monoxide poisoning are true except:
a. the oxygen carrying capacity of the blood is decreased
b. the oxyhemoglobin dissociation curve becomes shifted to the left, releasing less oxygen to the tissues
c. carboxyhemoglobin level of less than 30% produces minimal symptoms
d. treatment with 100% carbon dioxide is effective
A 29. The major routes by which toxic agents gain access to the body are through the ff., except:
a. blood d. skin
b. GIT e. parenteral route
c. lungs
C 30. Acute exposure by inhalation refers to continuous exposure for less than 2 hours, most frequently for:
a. 2 d. 5
b. 3 e. 6 hrs.
c. 4
a. atropine c. acetaminophen
b. aspirin d. cimetidine
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E 32. One group of thiol-containing enzymes that may play a critical role in cell injury and death as a result of oxidative
inactivation (oxidative stress) is:
a. Ca d. Mg
b. Na e. Al transportation alpase
c. K
D 33. Individuals who are deficient in glucose-6-dehydrogenase experience hemolysis following the treatment with these
drugs, except:
a. dapsone c. primaquine
b. ethacrynic acid d. tetracyclines
A 38. Direct hepatotoxicity has been observed with the ff. anesthetic agents:
a. halothane c. thiopental
b. nitrous oxide d. all of the above
A 39. A patient has resulted in acute hypertensive crisis after eating cheese. This interaction is possible if the patient is
on:
a. MAO inhibitor c. tetracyclines
b. aspirin d. all of the above
C 40. It is used in the manufacture of smoke bomb, antiseborrheic shampoos, in the treatment of bone fracture and
rickets.
a. bismuth d. cesium
b. boron e. chromium
c. cadmium
E 41. Its deficiency mimics diabetes mellitus, it is found in brown sugar & butter
a. bismuth d. cesium
b. boron e. chromium
c. cadmium
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a. nitrite d. arsenic
b. naphthalene e. beryllium
c. oxalate
B 54. A type of poison that causes blackening and severe corrosion in the mouth:
a. nitric acid d. phenol
b. sulfuric acid e. hydrochloric acid
c. ascorbic acid
a. ethanol c. atropine
b. digoxin d. naloxone
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C 63. Banned toxic substance in pandesal, cakes and other bakery products:
a. gemblid c. potassium bromate
b. venrupin d. sourine
D 67. The abuse of this drug is responsible for major medical and socio economic problems:
a. chloral c. nitrous oxide
b. chloral hydrate and ethanol d. ethanol
B 69. Conjuctival and bronchial irritation are primary signs of exposure to:
a. ergot c. ethyl alcohol
b. sulfur dioxide d. mercury
C 74. The universal antidote usually contains tannic acid, activated charcoal and:
a. calcium hydroxide c. magnesium hydroxide
b. aluminum hydroxide d. all of these
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C 92. Poison that converts the red hemoglobin to chocolate brown color
a. aniline c. both a & b
b. nitrobenzene d. ether
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c. both a & b
d. all of these
e. none of these
C 98. A branch of toxicology which is concerned with the medical and legal consequences of poisoning:
a. environmental toxicology c. forensic toxicology
b. experimental toxicology d. economic toxicology
A 100. Yellow or disturbed vision, disturbed respiration, eplileptiform convulsion can be caused by:
a. santonin d. all of these
b. muscarine e. none of these
c. atropine
D 101. Oxidation of pyrocatechol and hydroquinol may tint the urine color ____.
a. black d. green
b. yellow e. none of these
c. blue
A 107. The effects that occurs at the site of the first contact between the biological system and the toxicant.
a. local toxicity c. systemic toxicity
b. economic toxicity d. cumulative toxicity
A 108. This drug maybe added to local anesthetic solutions in order to prolong its action:
a. Epinephrine c. Atropine Sulfate
b.Sodium carboxymethylcellulose d. Norepinephrine
A 110. Peculiar stimulation (tingling) and paresthesia (numbness) of the sensory in nerves are symptoms of poisoning
due to:
a. aconite c. atropine
b. muscarine d. physostigmine
C 111. Potent cord convulsant, increases the excitability of the CNS at all level
a. morphine c. strychnine
b. muscarine d. both a & b
C 112. Obtained from coal tar
a. kerosene c. both a & b
b. naphthalene d. none of these
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B 117. Insecticide, fungicide, alloys in medicine, emetic drug, astringent and caustic, purification of water, escharotic
a. cadmium d. mercury
b. copper e. none of these
c. lead
A 118. Ultra short acting barbiturates are highly lipid soluble and rapidly penetrate the brain and is capable by inducing:
a. anesthesia c. none of the above
b. paralysis
B 124. Patients taking insulin must be monitored closely when given with anti-hypertensive drug:
a. Hydralazine c. Prazosin
b. Propranolol d. Methyldopa
B 125. The alkaloid found in Ipecac used for amoebic dysentery were evident poisoning symptom is violent purging with
bloody stools:
a. ephedrine c. isoquinoline
b. emetine d. methylxanthine
A 127. The cardinal rule or the first step to be considered in the treatment of poisoning is to:
a. remove the poison from contact with the victim
b. stop the action of the poison by giving the specific antidote
c. provide symptomatic or supportive care
d. fight against the tendency of death
B 128. Cases of heavy metal poisoning are concrete examples of:
a. sub-acute poisoning c. acute poisoning
b. chronic poisoning d. unknown
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C 130. Example of poison which exhibits both local and remote type of effects:
a. arsenic c. both a & b
b. cantharides d. none of the above
C 131. Substance intendd to prevent, destroy, repel or mitigate rats, mice, etc.
a. herbicides c. redenticides
b. hematocides d. molluscides
D 136. The mechanism by which 70% ethyl alcohol may act as a disinfectant is attributed to:
a. a metabolic degradation product of ethyl alcohol
b. the lack of alcohol dehydrogenase in bacterial cells
c. the inebriating effect of ethyl alcohol on cells
d. the ability of ethyl alcohol to denature proteins
C 139. Which of the following animals is used for flocculant precipitates with human blood:
a. cat c. rabbit
b. dog d. monkey
A 141. Strong black coffee or subcutaneous injection of Caffeine Citrate in the treatment of acute alcohol poisoning is
attributed to:
a. antagonistic stimulant effect of caffeine
b. oxidation of alcohol
c. depressant action of caffeine
d. hypotensive effect of caffeine
B 143. A type of insulin which causes exceptionally few allergic reactions is:
a. Protamine zinc insulin d. Lente insulin
b. NPH insulin e. Salicylate analgesics
c. Globin insulin
B 144. Atropine poisoning can be antagonized by:
a. Pralidoxime c. Phentolamine
b. Neostigmine d. Isoproterenol
C 145. The following symptoms of poisoning from Antimony (Sb) are similar to those of arsenic poisoning, except:
a. diarrhea of rice-water stool
b. severe dehydration and great thirst
c. garlic odor of the breath and suppression of urine
d. nausea and vomiting
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B 149. The following compounds have two sulfhydryl (-SH) groups, except:
a. DMSA c. DMPS
b. Penicillamine d. BAL
C 162. The mechanism of action involved in the use of EDTA as antidote for heavy metal poisoning is:
a. adsorption c. chelation
b. oxidation d. precipitation
B 163. A red color in the pyridine layer after adding NaOH develops in the presence of:
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a. Nitrobenzine c. Ethylene
b. Chloroform d. Phenacetin
C 176. Roofies:
a. alprazolam c. flunitrazepam
b. cannabis d. heroin
A 177. A toxic result on the developing organism may cause adverse effect during:
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a. cyanide c. alloin
b. capsaicin d. cysteine sulfoxide
C 185. Enters the breast milk and can cause neonatal narcotic dependence:
a. heroin c. both a and b
b. codeine d. none of the above
C 189. The following antidotes could be used to treat carbamate insecticide poisoning except:
a. atropine c. physostigmine
b. pralidoxime d. all of these
B 191. Morphine and its derivatives can cause the ff. except:
a. dyspnea d. respiratory paralysis
b. diarrhea e. all of these
c. constipation
C 193. Ethanol acts by preventing the conversion of this drug to formaldehyde by competing for dehydrogenase:
a. Chlorine c. methanol
b. Iodine d. all of these
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D 200. All the following metals have been found with substantial evidence to be carcinogenic in humans, except:
a. arsenic c. cadmium
b. beryllium d. manganese
A 203. Exposures at anytime during pregnancy poses a high risk of congenital structural abnormalities:
a. tretinoin c. carbamazepine
b. cyclophosphamide d. tamoxifen
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D 219. An antidote that acts by adsorption and is usually given when the nature of poison is unknown:
a. Potassium permanganeate c. Tannic acid
b. Ipecac syrup d. Charcoal
D 221. Non-therapeutic chemical most commonly involved in poisoning are the following except:
a. corrosives c. Solvents
b. Insecticides d. Analgesics
C 224. This substance is produced by the incomplete combustion of carbon or carbonaceous materials
a. nitrogen material c. carbon monoxide
b. sulfur oxides d. hydrogen sulfides
D 228. When reporting cases of poisoning like eating in a public restaurant, the case should be reported to the:
a. nurse d. public officer
b. family doctor e. BFAD
c. pharmacist
A 229. The major routes by which toxic agents gain access to the body are through the following except:
a. blood c. skin
b. GIT d. parenteral route
B 230. The most serious consequence of ingestion of liquid HC such as kerosene or gasoline is:
a. paralysis of the peristaltic motion of the GI tract
b. aspiration of the poison into the respiratory tract
c. destruction of body enzymes by the poison
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A 232. The specific antidote for the treatment of poisoning due to the oral ingestion of silver nitrate
B 235. The most effective antidote to arsenic, gold, mercury poisoning, which is a metal complexing agent
E 237. This is indicated for severe metabolic acidosis resulting from intoxicaton bymethanol, ethylene, glycol, salicylates
and excessive lactic acid.
B 238. This is indicated for anxiety, convulsions, muscle relaxant and chloroquin poisoning to antagonize cardiac
toxicity.
D 240. An antidote that acts by adsorption and is usually given when the nature of the poison is unknown.
B 243. The antidote for treating poisoning of bleaching agents like Zonrox.
A 244. The best antidote for formaldehyde poisoning, since it forms a nonpoisonous product which is methenamine.
E 249. This B-complex vitamin when administered to patients with methanol and ethylene glycol poisoning may
enhance the elimination of the toxic metabolite, formic acid.
A 250. This drug is indicated for acetaminophen overdose, which acts as sulfhydryl group donor substituting for the
livers usual sulfyldryl donor glytathione.
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D 253. Glucose with this drug is given to alcoholic and malnourished patient but may aggravate hyperglycemic ischemia
and braininjury.
C 265. Surface contamination with phenol can be washed using this substance.
B 266. The universal antidote usually contains tannic acid, activated charcoal and this drug.
A 267. These drugs can treat poisoning with organophosphates like parathion and malathion.
B 269. A person is likely to be more susceptible to digitoxin toxicity if digitoxin is given with:
a. neomycin c. Phenobarbital
b. hydrochlorothiazide d. thioridazine
C 270. The scientific name of the source of the very toxic ergonovine:
a. Papaver somniferum c. Claviceps purpurea
b. Croton tiglium d. Cantaris vesicatoria
B 271. Spoiled food brings about:
a. Botulism c. Tinnitus Cureum
b. Ptomaine d. none of these
A 272. The F value for a drug product is most closely related to its:
a. absolute bioavailability d. relative bioavailability
b. dosing rate e. route of administration
c. clearance rate
C 274. A condition of more or lesscomplete suspension of respiration and death may begin at the lungs:
a. Syncope c. Asphyxia
b. coma d. drowning
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C 280. Exerts their effects by interfering with the oxidation of the tissues:
a. narcotics c. asphyicants
b. irritants d. convulsants
C 282. Agents which produce exhaustion and cause marked loss of vital or muscular power:
a. tetanics c. asthenics
b. neurotics d. stimulants
C 284. Evidence obtained by examination of body organs and tissues after death:
a. experimental evidence c. post-mortem evidence
b. post-mortem evidence d. pre-mortem evidence
C 287. An adverse effect commonly associated with the use of theophylline products:
a. hypertensive crisis c. insomnia
b. skin rash d. tardive dyskinesia
D 288. Local action of poisons are best characterized by:
a. Cantharidin c. Corrosive acids
b. phosphorus d. all of the above
C 290. Evidence obtained by administering the suspected substance to some living animals and observing the effects:
a. circumstantial evidence c. experimental evidence
b. symptomatic evidence d. chemical evidence
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C 295. A type of poisoning produced by taking or absorbing for a protracted period small doses of a poison, thereby
producing gradual deterioration of function of tissues:
a. acute poisoning c. chronic poisoning
b. sub-acute poisoning d. none of the above
C 296. Dose which may be expected ordinarily to produce the therapeutic effects for which the preparation is employed:
a. maximum dose c. average dose (median)
b. minimum dose d. above average dose
C 297. Atmospheric substance with an oxidizing power which liberate iodine from the solution of KI:
a. carbon monoxide c. ozone
b. oxidants d. hydrogen sulfide gas
C 298. This substance is produced by the incomplete combustion of carbon or carbonaceous materials:
a. nitrogen materials c. carbon monoxide
b. sulfur oxide d. hydrogen sulfide
C 299. Characteristic color of the ammonium phosphor-molybdate precipitate for the presence of phosphorous:
a. violet precipitate c. yellow precipitate
b. black precipitate d. maroon precipitate
C 300. Characteristic type of precipitate of magnesium ammonium phosphate for the presence of phosphorous:
a. curdy, white precipitate c. crystalline, white precipitate
b. heavy, white precipitate d. white solution
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