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JMJ
University of St. La Salle Integrated School
Bacolod City
Science 10 Scaffold 2
2nd Quarter

Alphonsus Levi G. Cumalegre 10E

Mr. Rey Jastia October 27,
2017

I think that the learning material will talk about mutation. It will also show how mutations occur. The
most important ideas are that mutations can be grouped into two main categories based on where
they occur: somatic mutations which take place in non-reproductive cells and germ-line mutations
which occur in gametes or in cells that eventually produce gametes. Also, mutations aren't just
grouped according to where they occur frequently, they are also categorized by the length of the
nucleotide sequences they affect such as gene-level mutations which is the changing to short
stretches of nucleotides and chromosomal mutations which are mutations that alter longer stretches
of DNA. Another is that base substitutions are the simplest type of gene-level mutation, and they
involve the swapping of one nucleotide for another during DNA replication. For each main idea, the
questions that might be asked are that is it possible to have too many mutations and how to have a
disease-causing mutation but not have the disease. The terms/concepts/ideas that are not yet clear to
me are mutagens, how mutations can arise in cells of all types as a result of a variety of factors
including chance, and that if mutation can have widely varying individual effects. My summary of what
I learned about the article is that mutations prove beneficial to an organism by making it better able
to adapt to environmental factors. In other situations, mutations are harmful to an organism for
instance; they might lead to increased susceptibility to illness or disease. In still other circumstances,
mutations are neutral, proving neither beneficial nor detrimental outcomes to an organism.