Professional Documents
Culture Documents
TIME-BOUND
Growth Indicators
HEAD CIRCUMFERENCE
Height for age: determine stunted patient HC at birth 33-35 cms
Weight for age: determine underweight 1 yo 45 cms
patient
Weight for length: wasted or obese Mnemonics for weight
BMI: determine if patient is overweight/obese 0-6 mo Age in months x 600 + BW
6-12 mo Age in months x 500 + BW
1-6 yrs Age in years x 2 + 8
7-12 yrs (Age in years x 7)-5
2
Mnemonics for height 6 months Babbling
0-3 mo BW + 9cm 9 months Mama/papa
4-6 mo BW + 9cm + 8 cm 10 months Points to objects
7-9 mo BW + 9cm + 8 cm + 5 cm 12 months Single word with meaning
10-12 mo BW + 9cm + 8 cm + 5 cm+ 3 CM 4 yo Complete sentences
NEONATAL SEPSIS
DEVELOPMENTAL MILESTONE
GROSS MOTOR
3 months Head hold
5 months Roll over
7 months Sitting
9 months Pull to stand
12 months Walk Independently
16 months Run
24 months Jump with both feet
3 yo Jump forward
Pedal tricycle
4 yo Hop
5 yo Skip
FINE MOTOR
3 months Unfisted hand Risk factors:
5 months Midline hand play maternal infection during pregnancy
7 months Transfer object from one hand
prolonged rupture of membranes (18
to another
9 months Thumb-finger grasp hrs)
12 months Voluntary release prematurity
13 months scribbles Common organisms:
15 months Builds 2 towers
3 yo Handedness Bacteria:
4-4.5 yo Draw square GBS
5 yo Draw Triangle E. coli
EXPRESSIVE LANGUAGE Listeria monocytogenes
3 months Cooing Viruses
HSV
Enteroviruses
NOSOCOMIAL SEPSIS
Coagulase-negative Staphylococci
(especially Staphylococcus epidermidis
Gram-negative rods (including
Signs and symptoms
Pseudomonas, Klebsiella, Serratia, and
Fever temp instability Proteus) and fungal organisms
Not doing well predominate.
Poor feeding Viruses: enteroviruses, CMV, hepatitis A,
Edema adenoviruses, influenza, respiratory
Hypothermia (ominous sign) syncytial virus (RSV), rhinovirus,
parainfluenza, HSV, and rotavirus.
Tx: Empiric Antibiotics
Sclerema neonatorum
Ampicillin + 3rd generation
cephalosporin or aminoglycoside is a rare and severe skin condition that
is characterized by diffuse hardening of
the subcutaneous tissue with minimal
inflammation
Indicative of neonatal sepsis
LABORATORIES STUDIES
Evidence of infection
CULTURE (BLOOD, CSF)
DEMONSTRATION OF MICROORGANISM IN
TISSUE/ FLUID
MATERNAL / NEONATAL SEROLOGY (TORCH)
ANTIGEN DETECTION TEST (URINE/CSF)
GRAM STAINING
o especially helpful for the study of CSF.
o WBC in the samples can be maternal in
origin, and their presence along with
bacteria indicates exposure and possible
colonization but not necessarily actual
infection
Evidence of inflammation 3rd-7th day onset Jaundice first recognized
1. leukocytosis, increase immature/ total neutrophil after 1st week of life
count ratio Bacterial sepsis Breastmilk Jaundice
a. NV of WBC count in neonates: 9,000 30,000 UTI Septicemia
b. Immature neutrophil-mature neutrophil ratio Enterovirus Congenital atresia
should not be >0.2 Syphilis Hepatitis
2. acute phase reactant: Toxoplasmosis Galactosemia
a. C- reactive protein (CRP)- at 24 hrs with CMV Hypothyroidism
suspicion (in the liver); Erythrocyte Enzyme deficiencies
Sedimentation Rate (ESR)
Congenital hemolytic
3. pleocytosis in csf or pleural fluid
4. DIC: fibrin split products
anemia
5. cytokines: Interleukin-6
Evidence of multi organ systemic disease Breastfeeding Breast milk
a. metabolic acidosis; pH pCO2 jaundice jaundice
b. pulmonary function: pO2, pCO2 Onset 1st 3-5 days of 1st to 2nd
c. renal function: BUN, creatinine
life week of life
d. hepatic injury/ function: bilirubin, PT
e. bone marrow function: neutropenia, anemia, Incidence 12-13% 2-4%
thrombocytopenia Cause Inadequate Due to
supply of unidentified
NEONATAL JAUNDICE breastmilk factors in
leasing to breastmilk,
Physiologic Pathologic increased probably free
Presents after the Presents in the 1st 24 enterohepatic fatty acids;
48th hour of life hours of life circulation breast milk
TB increases not > 5 TB increases by > 0.5 may contain
mg/dl/day mg/dl/hr an inhibitor
TB peaks at 14-15 TB increases to > 15 of bilirubin
mg/dl mg/dl conjugation
DB < 10% of TB DB > 10% TB TX Increasing Increasing
Resolves in 1 week Persists beyond 1 breastfeeding breastfeeding
(term), 2 weeks week (term), 2 frequency to 8- frequency; at
(preterm) weeks (preterm) 10 times per day times,
perform
Pathologic jaundice 2nd-3rd day onset phototherapy
Erythroblastosis Breastfeeding jaundice Kramer Classification
fetalis Crigler-Najjar syndrome Head and neck: 6-8 mg/dl
Concealed Upper trunk: 9-12 mg/dl
hemorrhage Lower trunk, Thigh:12-16 mg/dl
Sepsis Arms: 13-15 mg/dl
TORCH Hands & Feet: > 15 mg/dl
ACUTE BACTERIAL MENINGITIS 3. Signs and symptoms of impending
cerebral herniation in child with
Etiology: probable meningitis
4. Severe cardiopulmonary compromise
1st 2 mo:
(Cricital illness)
o GBS, Gram negative enteric
5. Infection of the skin overlying the site
bacilli, Listeria monocytogenes
6. Thrombocytopenia with platelet count
2 months-12 years: <20x109/L
o S. pneumonia, H. influenza, N.
meningitides CSF findings consistent of bacterial meningitis
Mode of transmission: Pleocytosis
Hematogenous dissemination of High CSF protein level
microorganisms from a distant site of Low CSF sugar
infection
Treatment:
Manifestations:
N meningitides: Penicillin IV for 5-7 d
Headache, nausea, vomiting, anorexia, S. pneumonia: 3rd gen cephalosporin or
restlessness, irritability, fever, neck pain, Penicillin IV for 10-14 days
rigidity, obtundation, coma, focal neurologic Pen resistant: Vancomycin
deficits (vascular occlusion) H influenza meninigitidis:
Why is there neck rigidity? Dexamethasone IV
Complications: Echovirus
Coxsackie virus
Hydrocephalus: acute complication Adenovirus
(communicating type) CMV
Subdural effusions due to continued HSV
transudation
SIADH: may exacerbate cerebral edema->
hyponatremic seizures CSF findings:
Why do seizures occur? Normal glucose
Cerebritis, infarction, or electrolyte losses Normal to slightly increased protein
Lymphocytosis
Contraindications to LP
1. Suspected mass lesion of the brain
especially in posterior fossa
2. Suspected mass lesion of spinal cord
BENIGN FEBRILE SEIZURES
Occur between age 6-60 mo with a temp of 38
C or higher that are not result of CNS infection
or any metabolic imbalance and that occur in
the absence of a history of prior afebrile
seizure
Major risk factor of recurrence of FS
Age < 1 yr
Duration of fever < 24 hrs
Fever 38-39 C
< 12 mo: LP is recommended after their first
febrile seizure
Seizure Tremors
Chaotic, no pattern Rhythmic alternating
of movements, may movements of equal
be limited to a limb duration and
or multifocal amplitude usually
bilateral
Not influence by Exaggeration of
stimulation movements
No passive control With passive control
Other seizure None, except for
manfiestations autonomic
especially tonic eye symptoms like
movements tachycardia,
sweating
Frequently abnormal Normal
PCAP