Supplementary Data

Meta-analysis of antenatal infection and risk of asthma and eczema. Tingting Zhu, Li
Zhang, Yi Qu, Dezhi Mu

sTable 2. Search Strategy in EMBASE

1. maternal.ti,ab.
2. mother?.ti,ab.
3. prenatal.ti,ab.
4. pregnancy.ti,ab.
5. mother/
6. pregnancy/
7. 1 or 2 or 3 or 4 or 5 or 6
8. infection.ti,ab.
9. infectious.ti,ab.
10. chorioamnionitis.ti,ab.
11. illness.ti,ab.
12. inflammation.ti,ab.
13. febrile.ti,ab.
14. 8 or 9 or 10 or 11 or 12 or 13 or 14
13. asthma.ti,ab.
14. respiratory symptom.ti,ab
15.respiratory sounds.ti,ab.
16. wheeze.ti,ab.
17. respiratory hypersensitivity.ti,ab.
18. dermatitis.ti,ab.
19. eczema.ti,ab.
20.asthma/
21. 13 or 14 or 15 or 16 or 17 or 18 or
19 or 20
22. 7 and 14 and 21
23. Limit 22 to humans
24. Limit 23 to English
 Supplementary Data

Meta-analysis of antenatal infection and risk of asthma and eczema. Tingting Zhu, Li
Zhang, Yi Qu, Dezhi Mu

sTable 1. Search Strategy in PubMed

1. maternal
2. prenatal
3. pregnancy
4. gestational
5. antenatal
6. 1 OR 2 OR 3 OR 4 OR 5
7. Infection
8. infectious
9. Chorioamnionitis
10. illness
11. febrile
12.inflammation
12. 7 OR 8 OR 9 OR 10 OR 11 OR 12
13. Asthma
14. Respiratory Sounds
15. Respiratory Hypersensitivity
16. wheeze
17. respiratory symptom
18. Eczema
19. dermatitis
20.allergy
21. 13 OR 14 OR 15 OR 16 OR 17
OR 18 OR 19 OR 20
22. 6 AND 12 AND 21
23. Limit 22 to humans
24. Limit 23 to English
 Supplementary Data

Meta-analysis of antenatal infection and risk of asthma and eczema. Tingting Zhu, Li
Zhang, Yi Qu, Dezhi Mu

Table 3. The Newcastle-Ottawa Scale score of included studies

study Selection Selection of assess of outcome Comparability Assess of long enough Adequacy of

of non- exposure outcome of follow up follow up

exposured exposed

Cooper, 1 1 1 1 1 1 0 1
2015 [11] 7
Pesce, 1 1 1 1 1 1 1 1
2014 [2] 8
Collier, 1 1 1 1 1 1 1 1
2013 [12] 8
Murphy, 1 1 1 0 1 1 0 1
2014[13] 6
Algert, 1 1 1 1 1 1 0 1
2011[14] 7
Getahun, 1 1 1 1 1 1 0 1
2010 [1] 7
Keski- 1 1 1 1 2 1 1 1
Nisula,
2009
[15] 9
Kumar, 1 1 1 0 1 1 0 1
2008
[16] 6
Calvani, 1 1 1 1 1 1 1 1
2004
[17] 8
Hughes, 1 1 1 1 1 1 1 1
1999 [18] 8
Xu, 1 1 1 1 1 0 0 1
1999
[19] 6
 PRISMA 2009 Flow Diagram

Records identified through Additional records identified

database searching through other sources
(n = 698 ) (n = 9 )
Identfcaton

Records excluded for

Records after duplicates removed animals and other language
(n = 426 ) (n =42 )

Screening
Records excluded for clearly
Records screened
irrelevant, review, case reports
(n = 384 )
(n = 352 )

Full-text articles
assessed for eligibility
Full-text articles excluded, with
(n = 32 )
Eligibility reasons (n = 22 )

No maternal infection (15)

Studies included in No outcome data (6)

qualitative synthesis
(n = 10 ) Wheeze(1)

Included
Studies included in
quantitative synthesis
(meta-analysis)
(n = 10 )