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Critical Illness

Special Series

Effectiveness of an Early Mobilization


Protocol in a Trauma and Burns
Intensive Care Unit: A Retrospective
Cohort Study
Diane E. Clark, John D. Lowman, Russell L. Griffin, Helen M. Matthews,
Donald A. Reiff
D.E. Clark, PT, DScPT, Depart-
ment of Physical Therapy, School
of Health Professions, University of
Background. Bed rest and immobility in patients on mechanical ventilation or in
Alabama at Birmingham, 1530 an intensive care unit (ICU) have detrimental effects. Studies in medical ICUs show
3rd Ave S, Birmingham, AL that early mobilization is safe, does not increase costs, and can be associated with
35294-1212 (USA), and Acute decreased ICU and hospital lengths of stay (LOS).
Care Physical Therapy Depart-
ment, UAB Hospital, Birmingham,
Alabama. Address all correspon-
Objective. The purpose of this study was to assess the effects of an early mobi-
dence to Dr Clark at: clark@ lization protocol on complication rates, ventilator days, and ICU and hospital LOS for
uab.edu. patients admitted to a trauma and burn ICU (TBICU).
J.D. Lowman, PT, PhD, CCS,
Department of Physical Therapy, Design. This was a retrospective cohort study of an interdisciplinary quality-
School of Health Professions, Uni- improvement program.
versity of Alabama at Birmingham.

R.L. Griffin, PhD, Department of


Methods. Pre and post early mobility program patient data from the trauma
Surgery, School of Medicine, Uni- registry for 2,176 patients admitted to the TBICU between May 2008 and April 2010
versity of Alabama at Birmingham. were compared.
H.M. Matthews, Acute Care Phys-
ical Therapy Department, UAB Results. No adverse events were reported related to the early mobility program.
Hospital. After adjusting for age and injury severity, there was a decrease in airway, pulmonary,
and vascular complications (including pneumonia and deep vein thrombosis) post
D.A. Reiff, MD, Department of
Surgery, School of Medicine, Uni- early mobility program. Ventilator days and TBICU and hospital lengths of stay were
versity of Alabama at Birmingham. not significantly decreased.
[Clark DE, Lowman JD, Griffin RL,
et al. Effectiveness of an early Limitations. Using a historical control group, there was no way to account for
mobilization protocol in a trauma other changes in patient care that may have occurred between the 2 periods that
and burns intensive care unit: a could have affected patient outcomes. The dose of physical activity both before and
retrospective cohort study. Phys after the early mobility program were not specifically assessed.
Ther. 2013;93:186 196.]

2013 American Physical Therapy Conclusions. Early mobilization of patients in a TBICU was safe and effective.
Association Medical, nursing, and physical therapy staff, as well as hospital administrators, have
Published Ahead of Print: embraced the new culture of early mobilization in the ICU.
August 9, 2012
Accepted: August 2, 2012
Submitted: November 16, 2011

Post a Rapid Response to


this article at:
ptjournal.apta.org

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An Early Mobilization Protocol in a Trauma and Burns Intensive Care Unit

P
atients who are critically ill and gency department in 2008,18 and Setting
admitted to an intensive care approximately 1,000 of those At UAB Hospital, patients who are
unit (ICU) have traditionally patients were admitted to the critically ill and have injuries result-
been placed on bed rest.13 Progres- TBICU. Even with additional space ing from trauma or burns are admit-
sion to sitting and standing often has and staff, the volume of admissions ted to the TBICU. Excluded from this
been deferred in ICU populations created bottlenecks in the system, population are patients with trau-
until transfer to the floor, delaying especially related to TBICU outflow. matic brain injuries, who are admit-
mobility and increasing the risk for ted to the Neurological ICU. A mul-
complications associated with immo- Intended Improvement tidisciplinary team staffs the TBICU.
bility. This paradigm is being chal- To address capacity needs, hospital Attending physicians, fellows, resi-
lenged with recent evidence demon- administration and the trauma and dent general and trauma surgeons,
strating the safety and feasibility of burns medical and nursing staff and trauma intensivists oversee the
mobilizing patients early in medi- explored innovative ways to medical and surgical management of
cal4 7 and surgical8,9 ICUs. Some of improve patient care and flow patients in the TBICU. Physician
these studies showed that early through the trauma system. Concur- assistants facilitate patient manage-
mobilization of patients who were rently, members of the physical ther- ment and communication among the
critically ill also resulted in a reduc- apy department brought forward a disciplines. Registered nurses pro-
tion in patient complications and proposal to initiate an early mobili- vide the majority of patient interven-
ICU and hospital lengths of stay zation protocol for patients in the tions on a 1:1 or 2:1 patient-to-nurse
(LOS).2 8 TBICU. Early discussions with ratio. Nursing is responsible for titra-
trauma nursing and medical staffs tion of the sedation protocol and its
Prolonged immobility, sedation, and indicated that this was the ideal interruption to perform scheduled
mechanical ventilation during a crit- opportunity to design and imple- neurological checks throughout the
ical illness have been associated with ment such a protocol for the TBICU. day, as well as patient positioning
joint mobility restrictions, muscle The early mobility program team every 2 hours. Respiratory therapists
weakness, critical illness neuro- included representatives from the are present on the unit at all times
myopathies, pressure ulcers, deep medical, nursing and physical ther- and manage the ventilator protocols,
vein thrombosis (DVT), prolonged apy staff. inhaled medications, and the major-
mechanical ventilation, and psycho- ity of airway clearance interventions.
logical disturbances.3,10,11 Patients in Study Questions Prior to implementation of the early
a trauma and burns ICU (TBICU) are Although early mobility in medical mobility program, physical thera-
at similar risk for these complica- and surgical ICUs has been shown to pists were consulted as needed and
tions,3,10,12 which may contribute to be safe and feasible, the early mobil- followed no predetermined proto-
the body structure and function ity program team was unsure col. On average, patients were seen
impairments, activity limitations, whether early mobilization would be by physical therapists 2 to 3 days a
participation restrictions, and safe in a trauma and burns popula- week. Bed rest was the standard
decreased quality of life seen in tion. Thus, the teams preliminary
patients years after discharge from objective was to determine whether
the TBICU.1317 Yet, no previous an early mobility program could be Available With
studies have investigated the safety, safely implemented in this popula- This Article at
feasibility, or effectiveness of early tion. Subsequent primary objectives ptjournal.apta.org
mobilization in patients who are crit- were to assess the effects of an early
eTable: Common Injuries in
ically ill and who have sustained trau- mobility program on complication Patients Admitted to a Trauma
matic or burn injuries. rates, ventilator days, and LOS in the and Burns Intensive Care Unit
TBICU and hospital.
Listen to a special Craikcast
Local Problem on the Special Series on
The UAB Hospital is a 900-bed uni- Method Rehabilitation in Critical Care
versity hospital and an American Col- Ethical Issues with editors Patricia Ohtake, Dale
lege of Surgeonsverified level 1 The University of Alabama at Bir- Strasser, and Dale Needham.
trauma center. In 2004, a new emer- mingham (UAB) Investigational
Audio Podcast: Rehabilitation of
gency department and 28-bed TBICU Review Board approved this initia- Patients With Critical Illness
were opened to handle increasing tive as a quality improvement project symposium recorded at CSM
numbers of trauma visits each year. and waived the requirement for 2013, San Diego, California.
There were 54,654 visits to the emer- informed consent.2

February 2013 Volume 93 Number 2 Physical Therapy f 187


Downloaded from http://ptjournal.apta.org/ by Kimber Gerlich on February 27, 2013
An Early Mobilization Protocol in a Trauma and Burns Intensive Care Unit

P
atients who are critically ill and gency department in 2008,18 and Setting
admitted to an intensive care approximately 1,000 of those At UAB Hospital, patients who are
unit (ICU) have traditionally patients were admitted to the critically ill and have injuries result-
been placed on bed rest.13 Progres- TBICU. Even with additional space ing from trauma or burns are admit-
sion to sitting and standing often has and staff, the volume of admissions ted to the TBICU. Excluded from this
been deferred in ICU populations created bottlenecks in the system, population are patients with trau-
until transfer to the floor, delaying especially related to TBICU outflow. matic brain injuries, who are admit-
mobility and increasing the risk for ted to the Neurological ICU. A mul-
complications associated with immo- Intended Improvement tidisciplinary team staffs the TBICU.
bility. This paradigm is being chal- To address capacity needs, hospital Attending physicians, fellows, resi-
lenged with recent evidence demon- administration and the trauma and dent general and trauma surgeons,
strating the safety and feasibility of burns medical and nursing staff and trauma intensivists oversee the
mobilizing patients early in medi- explored innovative ways to medical and surgical management of
cal4 7 and surgical8,9 ICUs. Some of improve patient care and flow patients in the TBICU. Physician
these studies showed that early through the trauma system. Concur- assistants facilitate patient manage-
mobilization of patients who were rently, members of the physical ther- ment and communication among the
critically ill also resulted in a reduc- apy department brought forward a disciplines. Registered nurses pro-
tion in patient complications and proposal to initiate an early mobili- vide the majority of patient interven-
ICU and hospital lengths of stay zation protocol for patients in the tions on a 1:1 or 2:1 patient-to-nurse
(LOS).2 8 TBICU. Early discussions with ratio. Nursing is responsible for titra-
trauma nursing and medical staffs tion of the sedation protocol and its
Prolonged immobility, sedation, and indicated that this was the ideal interruption to perform scheduled
mechanical ventilation during a crit- opportunity to design and imple- neurological checks throughout the
ical illness have been associated with ment such a protocol for the TBICU. day, as well as patient positioning
joint mobility restrictions, muscle The early mobility program team every 2 hours. Respiratory therapists
weakness, critical illness neuro- included representatives from the are present on the unit at all times
myopathies, pressure ulcers, deep medical, nursing and physical ther- and manage the ventilator protocols,
vein thrombosis (DVT), prolonged apy staff. inhaled medications, and the major-
mechanical ventilation, and psycho- ity of airway clearance interventions.
logical disturbances.3,10,11 Patients in Study Questions Prior to implementation of the early
a trauma and burns ICU (TBICU) are Although early mobility in medical mobility program, physical thera-
at similar risk for these complica- and surgical ICUs has been shown to pists were consulted as needed and
tions,3,10,12 which may contribute to be safe and feasible, the early mobil- followed no predetermined proto-
the body structure and function ity program team was unsure col. On average, patients were seen
impairments, activity limitations, whether early mobilization would be by physical therapists 2 to 3 days a
participation restrictions, and safe in a trauma and burns popula- week. Bed rest was the standard
decreased quality of life seen in tion. Thus, the teams preliminary
patients years after discharge from objective was to determine whether
the TBICU.1317 Yet, no previous an early mobility program could be Available With
studies have investigated the safety, safely implemented in this popula- This Article at
feasibility, or effectiveness of early tion. Subsequent primary objectives ptjournal.apta.org
mobilization in patients who are crit- were to assess the effects of an early
eTable: Common Injuries in
ically ill and who have sustained trau- mobility program on complication Patients Admitted to a Trauma
matic or burn injuries. rates, ventilator days, and LOS in the and Burns Intensive Care Unit
TBICU and hospital.
Listen to a special Craikcast
Local Problem on the Special Series on
The UAB Hospital is a 900-bed uni- Method Rehabilitation in Critical Care
versity hospital and an American Col- Ethical Issues with editors Patricia Ohtake, Dale
lege of Surgeonsverified level 1 The University of Alabama at Bir- Strasser, and Dale Needham.
trauma center. In 2004, a new emer- mingham (UAB) Investigational
Audio Podcast: Rehabilitation of
gency department and 28-bed TBICU Review Board approved this initia- Patients With Critical Illness
were opened to handle increasing tive as a quality improvement project symposium recorded at CSM
numbers of trauma visits each year. and waived the requirement for 2013, San Diego, California.
There were 54,654 visits to the emer- informed consent.2

February 2013 Volume 93 Number 2 Physical Therapy f 187


Downloaded from http://ptjournal.apta.org/ by Kimber Gerlich on February 27, 2013
An Early Mobilization Protocol in a Trauma and Burns Intensive Care Unit

Table 1. Planning the Intervention


Trauma and Burns Intensive Care Unit (TBICU) Early Mobility Program A quality improvement framework
Variable Description
of Plan-Do-Check-Act (PDCA) was
used to develop and assess the early
Physical therapy Upon patient admission to the TBICU
referral mobilization initiative in the
Initial patient Physical therapy initial patient screening and assignment to mobility
TBICU.21,22 Peter Morris, MD, was
management level contacted to clarify details of the
Identification of passive-range-of-motion (PROM) precautionsa early mobility program developed
Physical therapist examination when appropriate
for patients in acute respiratory fail-
Intervention Level 1: Patient unconscious or with contraindications present to ure at Wake Forest Medical Center.5
active exercise and progression to sitting. Nursing standard of
care,b daily physical therapy screening. Progression criteria to
Planning meetings were held
level 2: medically able to begin sitting in bed (back supported) between January 2009 and April
and initiation of active-assisted exercises, able to follow 5 simple 2009 with the acute care physical
motor commands.
Level 2: Level 1 care continued. PT/NRTc: active-assisted to active
therapy manager, nurse manager,
exercises, mobility training; sitting up in bed (back supported). nurse educator, TBICU medical
Progression criteria to level 3: able to sit up (back supported) in director, and trauma program direc-
bed for 20 min, 3 times a day, and able to move arm against
gravity.
tor designated as program champi-
Level 3: Level 2 care continued. PT/NRT: sitting on edge of bed ons. Meeting discussions focused on:
initiated. Progression criteria to level 4: able to move leg against (1) development of an early mobility
gravity.
Level 4: Level 3 care continued. PT/NRT: standing and active
program tailored to the needs of the
transfers to chair with assistance initiated. Mobility progressed to trauma and burn population, (2) con-
walking. traindications to the protocol, (3)
Communication Daily rounds personnel and physical resources,
tools Mobility flow sheetd (4) staff education, (5) sedation man-
PROM/Mobility Precautions form
Team daily report agement, (6) barriers to implementa-
Discipline specific documentation tion of the protocol, and (7) commu-
a
Identification of soft tissue, skeletal, vascular, and integument impairments precluding range of nication and coordination among
motion.
b
team members.
Nursing standard of care: Positioning every 2 hours, PROM.
c
PTphysical therapist, NRTnursing and respiratory team (nurses, patient care technicians,
respiratory therapist).
d
Protocol development. The early
Data include patient mobility level, PT and nursing initials that intervention provided, and level
updates. mobility program team reviewed and
adapted the early mobility program
described by Morris et al5 that pro-
gressed ICU patient mobility based
activity level ordered upon admis- accident, pedestrian injury, fall, on medical stability, cognitive abili-
sion. This usual care for patients blunt or penetrating injury, machin- ties, and motor status. The program
in the TBICU was similar to that ery injury, or burn, results in an indi- description, which includes inter-
reported by Morris et al in 20085 and viduals need for critical care. Respi- ventions and progression criteria, is
Needham et al in 2010.3 ratory failure in this population detailed in Table 1. The nursing stan-
typically is not due to an acute infec- dard of care included positioning of
The trauma and burns population tion or exacerbation of a chronic pul- the patient every 2 hours and daily
differs significantly from those indi- monary condition, but rather due to routine passive range of motion
viduals admitted to medical ICUs. chest trauma, smoke inhalation, or (PROM) as determined by the phys-
Most individuals with traumatic and acute lung injury secondary to ical therapy staff. If more skilled
burn injuries are independent at the trauma. The mean Injury Severity range-of-motion activities were war-
community level prior to admission. Scale (ISS) score of patients admitted ranted, such as in patients with
Although comorbidities are present to the TBICU in 2009 to 2010 was burns, a physical therapist per-
in individuals with traumatic and 22.2 (SD9.4 35), indicating that formed this intervention. Active-
burn injuries, these comorbidities the majority of patients had injuries assisted to active exercises were ini-
are not the primary reason for an that were classified as severe to very tiated in level 2, with progression to
individuals admission to the TBICU severe.20 the use of weights and resistance
(eTable, available at ptjournal.apta. bands in levels 3 and 4. Patient
org).19,20 Rather, a precipitating trau- mobility was progressed by the phys-
matic event, such as a motor vehicle

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An Early Mobilization Protocol in a Trauma and Burns Intensive Care Unit

ical therapist and integrated into the Table 2.


nursing plan of care. Contraindications to Trauma and Burns Intensive Care Unit Early Mobility Program
Levels 3 and 4a
Contraindications to the early Variable Contraindication
mobility program. As the safety Unstable fractures Cardiovascular instability (eg, significant ventricular
of the early mobility program in a Spine instabilityb dysrhythmias, cardiac tamponade, acute or unstable
trauma and burns population had Conditions requiring continuous angina, myocardial infarction, critical hemodynamic
sedation or paralytic monitoring)
not been established before, the medications, such as open Vascular access requiring femoral or dorsal pedis arterial
TBICU medical director identified abdominal wounds (fascia line
specific contraindications to the ini- visible)b Pulmonary instability (eg, daily fiberoptic bronchoscopy
Use of pressor or inotropic to manage endobroncheal secretions or inhalation
tiation of early mobility program lev- medications to maintain injury, mechanical ventilation requiring FIO2 0.50 or
els 2 and higher (Tab. 2). Cardiovas- hemodynamic stability PEEP 10 cm H2O to maintain acceptable gas
cular, pulmonary and musculoskeletal exchange, pressure control ventilation with driving
pressures greater than 22 cm H2O)
instability formed the basis for the Nasotracheal intubation due to high extubation risk
majority of the contraindications. In a
FIO2fraction of inspired oxygen, PEEPpositive end-expiratory pressure.
contrast to studies conducted in the b
Levels 2 to 4.
medical ICU,57,23 we did not include
medical diagnoses such as neuro-
degenerative diseases as contraindi-
cations to early mobility, as they are Sedation management. The seda- therapist rounded with the nurse
rarely seen in our population. tion protocol did not change for the manager each morning to discuss
early mobility program. However, changes in patients status, including
Personnel and physical resources. patients in levels 2 to 4 received planned procedures for the day.
An additional full-time physical ther- more frequent sedation interrup- After conference, the medical staff
apist was required to support the tions to enable them to actively shared updated patient reports with
early mobility program. Administra- participate in the early mobility the physical therapist and clarified
tive approval for this position was program. weight-bearing and other precau-
obtained and interim staffing plans tions. Collaborative team work
developed until this individual was Barriers. The early mobility pro- ensured that mobility was prioritized
hired. More bedside chairs were allo- gram team members reported barri- while not interfering with other
cated to the TBICU to meet out-of- ers to implementation similar to care.
bed activities. those cited in other studies5,11,24,25:
time and a fear that more aggressive Physical therapy and nursing staff
Staff education. Nursing and mobility activities would result in documented completed activities on
physical therapy managers identified increased risk of cardiac and pulmo- a bedside flow sheet (Appendix 1).
educational needs for both staffs. nary complications. To address the As patient activity levels changed,
The physical therapy manager con- safety concerns, outcomes associ- the physical therapist indicated this
ducted overview sessions for all ated with previous early mobiliza- on the form. When applicable, the
team members highlighting the need tion studies were reviewed and rein- physical therapist also posted at the
for and benefits of an early mobility forced with staff. During the first bedside a PROM/Mobility Precau-
program. To address PROM and several weeks, team members under- tions form that described precau-
common positioning and range-of- estimated the time that care coordi- tions to PROM for the nursing staff
motion limitations seen in the TBICU nation required while overestimat- (Appendix 2). Conditions that lim-
population, physical therapists con- ing time needed for the performance ited performance of PROM included
ducted 30-minute instructional ses- of actual activities. As the teams those that required spine or limb
sions for all nursing staff, with reached higher levels of perfor- immobilization to prevent further
resource materials available at each mance, they no longer viewed time injury or promoted healing, such as
nursing station. Physical therapists as a barrier. skin grafting.
underwent more intensive training
in respiratory care procedures, Communication and collabora- Planning the Study of the
mechanical ventilation management, tion. Timely and efficient commu- Intervention
emergency procedures related to nication among team members was a Effectiveness of the early mobility
unintentional extubation, and seda- critical component to ensuring the program was assessed using mea-
tion and analgesia management. initiatives success. The physical sures that considered patient safety

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An Early Mobilization Protocol in a Trauma and Burns Intensive Care Unit

and outcomes. The hypotheses injury, and clinical characteristics. were adjusted for age and injury
tested were that early mobilization In addition, common comorbidities severity, as measured by the ISS. For
of patients in the TBICU would be that may have affected the ability of each model, time at risk was defined
safe and feasible and result in fewer patients to participate in the rehabil- as the time to the adverse event
complications, shorter TBICU and itation program were documented. (eg, pneumonia) or hospital dis-
hospital LOS, and no increase in charge, whichever occurred first. To
adverse events during a mobility ses- A primary outcome of interest was meet the assumptions of a Cox
sion. Results from the pilot program safety as related to nosocomial com- model (ie, hazards are proportional
at 4 months revealed a significant plications and adverse events. Each across categories of a certain vari-
decrease in ventilator-acquired pneu- complication was reviewed, and able), age and ISS were categorized.
monia and venous thromboembo- placed into one of the following cat- For all analyses, SAS version 9.2 (SAS
lism.26 The team agreed to continue egories: airway, acute respiratory Institute Inc, Cary, North Carolina)
the early mobility program for an distress syndrome, cardiovascular, was utilized. Descriptive data were
additional 8 months so that further hematologic, musculoskeletal/ obtained for billable physical ther-
data collection and analyses could be integumentary, neurologic, psychiat- apy units charged.
conducted to evaluate outcomes and ric, pulmonary excluding pneumo-
processes. The selected study design nia, pneumonia, renal/genitourinary, Results
was a retrospective cohort study. sepsis, vascular, DVT, and pressure Institutional Outcomes
Data were collected through estab- ulcer. For each patient, the occur- Delivery of patient care in the TBICU
lished hospital electronic systems rence of a complication was counted was transformed from a multidisci-
that included risk management sys- only once (ie, only the first occur- plinary approach in which each dis-
tems for documentation of incidents rence of the complication was con- cipline operated in parallel to an
and adverse events, the trauma reg- sidered). Adverse events related to interdisciplinary approach where
istry for demographic, injury, and safety during mobility sessions were collaboration, communication, and
clinical characteristics of the partici- categorized as: involuntary or self- problem solving occurred beyond
pants, and the billing system for con- extubation, decannulation (vascular the confines of individual disci-
firmation of increased physical ther- device), fall, cardiac event (eg, plines. Nurses, physical therapists,
apy intervention in the TBICU. arrest, new onset of ventricular respiratory therapists, and physi-
tachycardia or fibrillation, hypoten- cians worked together to prioritize
Methods of Evaluation sion, severe hypertension), or respi- patients mobility needs. The early
Clinical and demographic data were ratory event (eg, distress, failure). mobility program teams assumed
collected for patients admitted to the Billing records for two 3-month peri- accountability for their performance
UAB Hospital TBICU from May 2008 ods in 2008 and 2009 (AugustOcto- and developed self-management
through April 2010 from the UAB ber) were used as a surrogate marker skills that promoted ownership of
trauma registry. Registry data are for dose of mobility. goals and a shared decision-making
entered by trained registrars, with process.
data collected from medical charts, Data Analysis
and are compared with documenta- Demographic, injury, and clinical Patient Outcomes
tion in the electronic record to verify characteristics were compared From May 2008 through April 2010,
findings. Additionally, interrater reli- between the early mobility pro- 2,176 patients were admitted to the
ability analyses are performed grams implementation groups using TBICU, 1,044 of whom were admit-
among sampled records to ensure the chi-square test and the t test for ted prior to early mobility program
data are entered correctly among categorical and continuous variables, implementation and 1,132 were
registrars. Those patients admitted respectively. Additionally, a chi- admitted after early mobility pro-
from May 2008 through April 2009 square test was used to determine gram implementation (Tab. 3).
were categorized as admitted prior whether the early mobility pro- Those admitted before early mobility
to early mobilization implementation grams implementation groups dif- program implementation were
(pre early mobility program), and fered by comorbidity status. A Cox younger (P.01), were more likely
those admitted from May 2009 proportional hazards model was to be male (P.02), and had higher
through April 2010 were categorized used to estimate risk ratios (RRs) and ISS scores (23.6 versus 22.2, P.01)
as admitted after early mobilization 95% confidence intervals (CIs) for (Tab. 3). Regarding comorbidities,
implementation (post early mobility the association between early mobil- those admitted to the ICU prior to
program). For each patient, informa- ity program implementation and early mobility program implementa-
tion was collected on demographic, complication occurrence. Models tion were less likely to have arthritis

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An Early Mobilization Protocol in a Trauma and Burns Intensive Care Unit

(P.001), cardiovascular disorders Table 3.


(P.01), diabetes (P.001), neuro- Demographic, Injury, and Comorbidity Characteristics of Patients Admitted to an
logic disorders (P.03), sleep apnea Intensive Care Unit Prior to and After Implementation of an Early Mobility Program
(EMP)a
(P .04), or pulmonary disorders
(P.03; Tab. 3). Prior to EMP After EMP
Characteristic (n1,044) (n1,132) Pb

The overall hospital LOS was signifi- Demographic


cantly shorter, by 2.4 days, in the Age (y), X (SD) 44.1 (18.5) 46.6 (19.6) <.01
post early mobility program group Male (%) 75.1 70.5 .02
(P.02; Tab. 4). When adjusted for Race/ethnicity (%) .59
the ISS score, hospital stay length
Caucasian 69.6 70.0
remained 1.5 days shorter but was
statistically insignificant (data not African American 26.9 25.9

shown). There were no differences Hispanic 2.5 3.3


in TBICU days, mechanical ventila- Asian 0.4 0.5
tion days, mortality, and discharge Other 0.6 0.3
disposition between the 2 groups.
Injury

Mechanism of injury (%) .97


Based on significant differences in
complication rates between groups Blunt 75.4 75.1

(Tab. 4), we adjusted for age and Penetrating 15.1 15.5


injury severity and calculated RR val- Burn 9.5 9.5
ues (Tab. 5). After early mobility ISS score, X (SD) 23.6 (12.8) 22.2 (12.8) .01
program implementation, patients
GCS score, X (SD) 11.9 (4.9) 11.9 (4.9) .72
were less likely to have pneumonia
Spinal cord injury (%) 7.1 5.5 .13
(RR0.79, 95% CI0.66 0.93),
DVT (RR0.67, 95% CI0.50 Long bone fracture (%) 40.6 41.2 .78

0.90), airway complications (RR Upper extremity 22.5 23.8 .49


0.52, 95% CI0.35 0.76), pulmo- Lower extremity 28.7 28.8 .97
nary complications (RR0.84, 95% Comorbidity (%)
CI0.74 0.95), or vascular compli-
Arthritis 5.5 9.7 <.001
cations (RR0.58, 95% CI
Cardiovascular disorder 31.8 37.0 .01
0.45 0.75).
Cancer 1.6 2.1 .44

Although not significantly different, Diabetes 3.5 10.2 <.001


a trend toward an increased relative End-stage renal disease 1.5 1.5 .87
risk for cardiovascular complications Gastrointestinal disorder 0.6 1.2 .14
was observed for the post early Genitourinary tract disorder 0.2 0.0 .15
mobility program group (RR1.26,
Hematologic disorder 3.0 4.3 .11
95% CI0.99 1.59) (Tab. 5). Due to
this trend for increased cardiovascu- Musculoskeletal disorder 5.0 6.5 .13

lar complication risk, further analy- Neurologic disorder 8.2 10.9 .03
ses were performed. Models were Obstructive sleep apnea 1.6 3.0 .04
created for each individual type of Previous trauma 7.1 6.1 .38
cardiovascular complication. A nota- Psychiatric disorder 14.5 16.7 .15
ble, but statistically insignificant, risk
Pulmonary disorder 7.7 10.5 .03
was observed for pericardial effusion
or tamponade (RR4.11, 95% CI Substance abuse 31.6 29.9 .39

0.88 19.09). Nonspecified cardio- Smoker 37.5 37.4 .96


vascular complications (RR1.81, a
ISSInjury Severity Scale, GCSGlasgow Coma Scale.
b
95% CI1.16 2.83) were statisti- Based on chi-square and t-test analysis for categorical and continuous data, respectively. Statistically
significant items indicated in bold type.
cally significantly increased in the
early mobility program group. Dys-
rhythmia, unexpected cardiac arrest,

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An Early Mobilization Protocol in a Trauma and Burns Intensive Care Unit

Table 4. able units per visit increased from


Comparison of Hospitalization and Disposition Characteristics and Complication 1.5 to 2.2.
Rates of Patients Admitted to an Intensive Care Unit (ICU) Prior to and After
Implementation of a Trauma and Burns Intensive Care Unit Early Mobility
Program (EMP)
Discussion
Summary
Prior to EMP After EMP This quality improvement initiative
Characteristic (n1,044) (n1,132) Pa
demonstrated that early mobilization
Clinical of patients admitted to a TBICU was
Days in hospital, X (SD) 19.2 (28.2) 16.8 (18.4) .02 safe and effective. Neither acute
Days in ICU, X (SD) 11.0 (16.2) 10.4 (14.0) .33 adverse events nor increased compli-
Days of ventilator support, X (SD) 8.9 (17.4) 7.8 (13.4) .08 cations associated with early mobil-
ity were reported. Our results indi-
Dead (%) 13.2 11.8 .33
cate that during the early mobility
Discharge disposition (%) .31
program period, patients in the
Acute care hospital 1.1 0.9 TBICU significantly reduced airway,
Home 69.8 67.9 pulmonary, and vascular complica-
Long-term acute care 1.8 2.5 tions. Hospital LOS was not found to
Psychiatric facility 1.1 2.0 be different when adjusted for injury
severity and age, as were days of ven-
Rehabilitation facility 17.4 18.1
tilator support and TBICU LOS.
Skilled nursing facility 6.0 6.8

Other 2.9 1.8 Interpretation and Relation to


Complication category (%) Other Evidence
Airway 7.1 3.5 <.001 Early mobility of patients in critical
Acute respiratory distress syndrome 1.8 1.5 .62 care settings has gained momentum
in the literature over the past few
Cardiovascular 12.2 15.2 .04
years, with at least 29 articles pub-
Gastrointestinal 9.0 8.0 .38
lished on the topic since January
Hematologic 57.7 54.5 .14 2007.112,2325,2739 Of these publica-
Hepatic/pancreatic/splenic 1.4 1.5 .99 tions, there are at least 6 quality
Musculoskeletal/integumentary 10.7 10.8 .93 intervention studies assessing the
Infection (excluding pneumonia 10.9 9.6 .32 role of exercise or mobility for
and sepsis) patients in an ICU setting.35,7,8,31 For
Neurologic 13.5 14.3 .61 most of our comparisons, we will
Psychiatric 3.4 1.7 .02
focus on the 3 studies most similar to
ours, although the setting for these
Pulmonary excluding pneumonia 49.2 42.2 <.001
studies was a medical ICU. Our early
Renal/genitourinary 18.3 15.0 .04
mobility interventions were mod-
Vascular 15.3 8.5 <.001 eled after that of Morris et al5 and
Deep vein thrombosis 10.9 6.7 <.001 were very similar to those of the
Pneumonia 27.9 22.4 <.01 more recent studies of Schweickert
Pressure ulcer 7.0 7.3 .77
et al7 and Needham et al.3
Sepsis 7.9 6.9 .41
Early mobilization of patients who
a
Based on chi-square test. Statistically significant items indicated in bold type. are critically ill is safe as measured by
mortality rates, adverse events, and
discontinuation in therapy sessions
due to patient response to activity.
cardiogenic shock, myocardial patients during a mobility event in In our study, mortality did not signif-
infarction, and shock rates remained either time period. Billable units icantly change with implementation
unchanged. increased 100% in the post early of the early mobility program. Both
mobility program period, with an Schweikert et al7 and Needham et al3
No adverse events were reported in average of 21.1 units charged per also reported no changes in mortal-
the risk management system for day (Tab. 6). Physical therapy bill- ity. As defined by our study protocol,

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An Early Mobilization Protocol in a Trauma and Burns Intensive Care Unit

Table 5.
Crude and Adjusteda Risk Ratios (RRs)b and Associated 95% Confidence Intervals (95% CIs) for the Association Between Hospital
Complications and Implementation of an Early Mobility Program (EMP) Among Patients in a Trauma and Burns Intensive
Care Unit
Prior to EMP After EMP
Variable (n1,044) (n1,132) Crude RR (95% CI) Adjusted RR (95% CI)

Complications (%)

Airway 7.1 3.5 0.50 (0.340.73) 0.52 (0.350.76)

Pulmonary 49.2 42.2 0.81 (0.720.92) 0.84 (0.740.95)

Pneumonia 27.9 22.4 0.78 (0.660.92) 0.79 (0.660.93)

Cardiovascular 12.2 15.2 1.33 (1.061.68) 1.26 (0.991.59)

Dysrhythmia 6.0 6.8 1.20 (0.851.68) 1.10 (0.781.55)

Unexpected cardiac arrest 2.4 2.3 0.99 (0.571.71) 0.97 (0.561.69)

Cardiogenic shock 0.1 0.1 0.92 (0.0614.74) 0.88 (0.0514.20)

Congestive heart failure 0.5 0.4 0.78 (0.212.92) 0.68 (0.182.64)

Myocardial infarction 0.8 1.1 1.78 (0.714.47) 1.36 (0.533.47)

Pericardial effusion or tamponade 0.2 0.7 4.25 (0.9219.69) 4.11 (0.8819.09)

Shock 1.7 2.2 1.23 (0.672.27) 1.28 (0.692.36)

Not fully specified 3.0 5.0 1.87 (1.202.91) 1.81 (1.162.83)

Vascular 15.3 8.5 0.57 (0.440.73) 0.58 (0.450.75)

Deep vein thrombosis 10.9 6.7 0.64 (0.480.85) 0.67 (0.500.90)

Psychiatric 3.4 1.7 0.60 (0.351.04) 0.60 (0.351.03)

Renal/genitourinary 18.3 15.0 0.86 (0.701.06) 0.83 (0.671.02)


a
Adjusted for age and injury severity. Statistically significant items after adjustment indicated in bold type.
b
Estimated from Cox proportional hazards regression.

no adverse events occurred during complications (eg, adult respiratory given the significant reduction in
early mobilization. Schweikert et al7 distress syndrome, pneumothorax, airway, pulmonary, and pneumonia
reported one case in which decan- pulmonary embolism) seen after the complications found in this study,
nulation of the radial artery catheter early mobility program was likely perhaps daily fiberoptic bronchos-
occurred. In other studies, tempo- due to improved ventilation/perfu- copy did not need to be an absolute
rary or permanent session disrup- sion matching, lung compliance, and contraindication to mobility. The lit-
tions in therapy were considered to mucociliary clearance and a reduc- erature suggests that early mobility
be adverse events and were reported tion in the work of breathing in and airway clearance techniques
to occur in 4% and 16% of sessions.6,7 upright postures.40 In retrospect,

We did not have any significant


increase in iatrogenic complications Table 6.
in the early mobility group. To the Comparison of Physical Therapy Utilization for Patients in a Trauma and Burns
contrary, we found a decrease in Intensive Care Unit Admitted Prior to and After Implementation of an Early Mobility
many complications. Based on our Program (EMP)a
outcomes, we found that ambulation Prior to
with endotracheal intubation was a Variable EMP After EMP
safe intervention. Airway complica- Days PT provided 68 71
tions related to reintubation were Midnight census, X (SD) 25.5 (1.0) 25.0 (1.8)
reduced 50% in the post early PT billable units (total) 749 1,498
mobility program group, and no
PT billable units/days PT provided 11.0 21.1
unplanned extubation occurred dur-
ing any mobility event. A reduction PT billable units/visit, X (SD) 1.5 (0.3) 2.2 (0.3)

in pneumonia and other pulmonary a


PTphysical therapy.

February 2013 Volume 93 Number 2 Physical Therapy f 193


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An Early Mobilization Protocol in a Trauma and Burns Intensive Care Unit

may be effective as interventions for days in the post early mobility pro- disciplinary to interdisciplinary
smoke inhalation.41,42 gram group, this finding was statisti- patient care. From the outset, the
cally insignificant. Morris et al5 found quality improvement leadership
Because hospitalization, immobility, a decrease in overall hospital LOS group empowered bedside caregiv-
and especially orthopedic and spinal from 14.5 days to 11.2 days (P.006) ers to work collaboratively and
trauma are risk factors for DVT,43 when adjusted for body mass index, develop ownership of the early
the reduced incidence of DVT in Acute Physiology and Chronic mobility program.30 The concept of
the early-mobility group could be Health Evaluation II scores, and vaso- flexibility evolved from that defined
explained by early active lower- pressors. Unlike other studies,3,5 our as a willingness to change individual
extremity exercises with physical ther- study did not demonstrate that ICU schedules to the willingness to com-
apy and frequent out-of-bed mobility LOS was changed as a result of early promise and develop new skill sets
episodes.44 As proximal DVTs are mobilization. Although the factors outside those traditionally assumed
prone to embolization, the reduction that may have contributed to an by a profession.30 Long-term out-
in DVT and other vascular complica- overall shorter LOS are not clear, we comes were linked to team pro-
tions in the present study also may postulate that patients in the post cesses, enabling team members to
explain the decrease in nonpneumo- early mobility program group were recognize that individual effort alone
nia pulmonary complications, which transferred to the floor having expe- was not sufficient in optimizing
include pulmonary embolism. Previ- rienced fewer complications, thus patient outcomes. Bailey et al30 sug-
ous studies examining DVT and pul- decreasing the extent of further gested that collaboration is as impor-
monary embolism incidence have not rehabilitation services and other tant as or more important than indi-
shown such a decrease.5,8 required care prior to discharge. vidual effort when teams must
Morris et al5 suggested that factors deliver complex care. Thomsen and
On initial analysis, only cardiovascu- such as care standardization, a mul- colleagues study demonstrated that
lar complications increased in the tidisciplinary approach to mobility, an intensive care environment
post early mobility program group. earlier initiation of physical therapy, focused on early mobility by a dedi-
Although they were statistically and a reduction in missed visits may cated and trained team was the sin-
insignificant after adjusting for age contribute to decreased LOS. gle strongest predictor of ambulation
and injury severity, we decided that compared with other medical ICUs
further exploration was warranted. It is difficult to accurately assess how in the facility.29
Several factors may have contributed much mobility or physical activity
to the noted increase in cardiovas- patients received after implementa- As a result of our studys findings, the
cular complications. Although the tion of the early mobility program. acute physical therapy department
incidence of cardiovascular comor- Although the TBICU census and has justified establishing 2 additional
bidities was higher in the early mobi- number of days physical therapy full-time physical therapist positions
lization group, both groups experi- staff provided care in the TBICU dur- to support the program in the TBICU
enced similar rates of dysrhythmias, ing this 92-day period was not differ- and establishing one in the surgical
unexpected cardiac arrest, conges- ent, there was a 100% increase in ICU. Development of a protocol for
tive heart failure, cardiovascular total physical therapy billable units, nurses and physical therapists has
shock, and myocardial infarction, as well as an increase in the units of further integrated early mobilization
which conceivably could be related physical therapy provided per day of into the routine care of patients in
to mobility complications in an ICU service and per visit. This measure the TBICU despite staff turnover. As
population. Pericardial effusion, tam- of dosage indicates a substantial an ongoing component of quality
ponade, and unspecified cardiovas- increase in both frequency and dura- improvement, we plan to conduct
cular complications were higher in tion of interventions provided by periodic chart audits to assess pro-
the early mobility program group; physical therapy staff, but it fails gram fidelity and provide ongoing
however, no evidence supports early to capture the patients mobility educational sessions for new
mobility as a likely cause of these throughout the day with nursing and employees.
complications. Blunt trauma to the respiratory therapy, as well as on
chest, surgical trauma, or infections their own. Limitations
are more likely explanations in our The ability to generalize findings
population.45 Early mobilization protocols are pos- from this study is constrained by the
sible due to a deliberate effort to retrospective study design. A second
Although hospital LOS adjusted for involve all stakeholders in the plan- limitation to our study is that we
injury severity was reduced by 1.5 ning process and a shift from multi- were unable to confirm the mobility

194 f Physical Therapy Volume 93 Number 2 February 2013


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An Early Mobilization Protocol in a Trauma and Burns Intensive Care Unit

dose or to specifically quantify the Kelly Sheils, BSN, Twanda Coates, BSN, 11 Morris PE. Moving our critically ill
Tammy Herdeman, members of the TBICU patients: mobility barriers and benefits.
physical activity levels of individual Crit Care Clin. 2007;23:120.
Trauma Staff, and the Trauma Registry Staff
patients in our early mobility pro- 12 Morris PE, Herridge MS. Early intensive
for assistance.
gram. Additional variables related to care unit mobility: future directions. Crit
Pilot data were presented at the Acute Care Care Clin. 2007;23:97110.
physical therapy interventions, such
Section of the Combined Sections Meeting 13 Holtslag HR, Post MW, van der Werken C,
as the number of visits provided Lindeman E. Return to work after major
of the American Physical Therapy Associa-
per protocol level, were difficult to tion; February 1720, 2010; San Diego,
trauma. Clin Rehabil. 2007;21:373383.
measure, as the patients frequently California. 14 Holtslag HR, van Beeck EF, Lindeman E,
Leenen LP. Determinants of long-term
moved between levels and ade- functional consequences after major trau-
This publication was made possible by the
quate staff were not available to con- UAB Center for Clinical and Translational Sci-
ma. J Trauma. 2007;62:919 927.
duct large-scale chart reviews. Fem- ence Grant UL1TR000165 from the National 15 ODonnell ML, Creamer M, Elliott P, et al.
Determinants of quality of life and role-
oral lines were listed as one of our Center for Advancing Translational Sciences related disability after injury: impact of
contraindications to the early mobil- (NCATS) and National Center for Research acute psychological responses. J Trauma.
Resources (NCRR) component of the 2005;59:1328 1334.
ity program, but recent evidence National Institutes of Health (NIH). Its con- 16 Toien K, Bredal IS, Skogstad L, et al. Health
suggests that patients with these tents are solely the responsibility of the related quality of life in trauma patients.
lines may be safely mobilized.38 authors and do not necessarily represent the Data from a one-year follow up study com-
pared with the general population. Scand
official views of the NIH. J Trauma Resusc Emerg Med. 2011;19:22.
Conclusions DOI: 10.2522/ptj.20110417 17 Ulvik A, Kvale R, Wentzel-Larsen T,
Early mobility in patients who are Flaatten H. Quality of life 27 years after
major trauma. Acta Anaesthesiol Scand.
critically ill and have traumatic and 2008;52:195201.
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Appendix 1.
Trauma and Burns Intensive Care Unit Mobility Team Flow Chart (Not Part of
Medical Record)a
Date/Initial Date/Initial Date/Initial

Level 1

Level 2

Level 3

Level4

Nursing:

PROM 1/day with bath

Patient in chair position 3, 20 min/day

PT:

Initial evaluation

Treatment
a
PROMpassive range of motion, PTphysical therapy.

Appendix 2.
PROM/Mobility Precautions Forma

L Upper Extremity WB R Upper Extremity WB

Instructions: Instructions:

L Lower Extremity WB R Lower Extremity WB

Instructions: Instructions:

Hip Precautions

a
PROMpassive range of motion, Lleft, Rright, WBweight-bearing status.

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