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a. Heart
b. Kidney
c. Lung
d. Liver
a. Coagulative necrosis
b. Caseous necrosis
c. Enzyme necrosis of fat
d. All the above
5. Progressive atrophy of the brain in later adult life is thought to be part due to
a. Decreased workload
b. Loss of innervation
c. Diminished blood supply
d. Loss of endocrine stimulation
6. Inflammation is
7. The most common mechanism for the formation of leaky endothelium in inflammation is
a. Endothelial retraction
b. Direct endothelial injury
c. Leukocyte mediated endothelial injury
d. Endothelial cell contraction
a. Extravasation of the leukocyte occurs in the order of: adhesion to the wall,
margination and then rolling of the leucocyte across the endothelial wall.
b. Selectins are the primary molecule who play roles with neutrophil activation
c. Integrins are involved in firm adhesion of the leucocyte to the cell wall
d. Endothelial cells will take 6-12hrs before they express their selctin ( E selectin ) in
inflammation
a. When mesothelial cells of the peritoneum, pleural and pericardial linings secrete
fluid it is usually of a fibrinous nature
b. A serous exudation consists primarily of neutrophils, liquefactive necrosis and
oedematous fluid
c. When there are large vascular leaks or an associated procoagulant stimulus you
commonly see a suppurative exudate
d. Ulcers can only occur when tissue necrosis and the resultant inflammation is on or
near a surface
11.In chronic inflammation, all are true except
a. Alcohol abuse
b. Protein malnutrition
c. XI-antitrypsin deficiency
d. CCl4
e. Renal failure
f. Paget’s disease
g. Sarcoidosis
h. Hypoparathyroidism
18. Depletion of AtP cause all EXCEPT
a. efflux of Ca2+
b. efflux of K
c. influx of Na+
d. decrease pH cells
19.The most common causes of fatty liver in the developed world are
a.Hypercholesterolaemia and lipid storage diseases
b.Alcohol abuse and hypercholesterolaemia
c.NAFLD and alcohol abuse
d.NAFLD and hypercholesterolaemia
21. .Regardig white cell extravasation in acute inflammation which of the following pairs are
incorrect
22.Which of the following disorders are examples of chronic leukocyte induced injury
a.Arthritis
b.Asthma
c.Atherosclerosis
d.Septic shock
b.Chemotaxis
d.Vasodilatation
c. Neutrophils release proteolytic enzymes that clean out debris and bacteria
c. The new vessels in angiogenesis are tight and restrict passage of plasma
proteins.
b. Keloid scars grow beyond the boundaries of the original wound and don't
regress
d. The tensile strength after one week in an incisional surgical wound is about
10% of unwounded skin.
a. Anergy
b. Thymic deletion
c. Suppression by regulatory T-cells
d. Antigen sequestration