DRUG STUDY
GENERIC NAME: Biperiden
Brand name: Akineton
Drug Classification: Anticholinergic
DOSAGE, ROUTE,
FREQUENCY (prescribed and
recommended)
 Parkinsonism:
2 mg PO TID to QID;
individualize dosage.
Maximum, 16 mg/day (8
tablets).
 Drug-induced
Extrapyramidal Disorders:
2 mg PO daily to TID
CONTRAINDICATION/S
 Hypersensitivity to Benztropine
 Angle-closure Glaucoma
 Pyloric or Duodenal Obstruction
 Peptic Ulcer
 Myasthenia Gravis
SIDE EFFECTS and
INDICATION MECHANISM OF ADVERSE REACTIONS
ACTION (by system)
 Adjunct in therapyAnticholinergic activity in CNS: Disorientation
of parkinsonism. the CNS that is believed to CV: Orthostatic hypotension
help normalize the Dermatologic: Rash
 Relief of hypothesized imbalance of EENT: Blurred vision
symptoms of cholinergic and GU: Urinary retention
extrapyramidal dopaminergic
disorders that neurotransmission in the
accompany basal ganglia in the brain of
phenothiazine a parkinsonism patient.
therapy
NURSING RESPONSIBILITIES
(at least 10)
1. Give with caution, and reduce dosage in hot weather.
2. Give with meals if GI upset occurs.
3. Ensure that patient voids just before receiving each dose of drug if
urinary retention is a problem.
4. Drug interferes with sweating and ability of body to maintain heat
equilibrium.
5. Decrease dosage or discontinue temporarily if dry mouth makes
swallowing or speaking difficult.
Patient’s Name / Room No.