1.

In the classification of lipids, the following are examples of precursor and derived
lipids. (Katzung, p212)
1. Ketone bodies
2. Phospholipids
3. Glycolipid
4. Fatty acid
5. Steroids
6. Wax
a. 1, 2, 3 b. 2,4,5,6 c. 1,4,5 d. 1 and 6 e. all of the above

2. The following are neutral lipids (Katzung, p212)

1. Acylglycerol
2. Phospholipids
3. Cholesterol
4. Glycolipid
5. Fatty acid
6. Cholesteryl esters

a. 3 and 6 b. 1,2,3,4 c. 4 and 5 d. 1,3,5,6 e. 1,3,6

3. During fatty acid synthesis, the 2 carbon donor is the ____, while ____ supplies the
electrons.
a. Malonyl Coa, NADPH
b. Palmitate, Malonyl Coa
c. NADPH, Palmitate
d. Acetyl Coa Carboxylase, Fatty Acid Synthase
e. Citrate, NADPH

4. The following statements are true:

a. The presence of the unsaturated fatty acid(s) decrease(s) the Tm of the lipid
b. Diacylglycerol is the initial acceptor of fatty acids during TAG synthesis
c. The major pathway for catabolism of fatty a cids is a cytosolic pathway called β-
oxidation
d. In the first step of fatty acid translocation, the acyl group is transferred from CoA to
carnitine by carnitine palmitoyltransferase II (CPT-II)
e. The oxidation of palmitoyl Coa yields a net ATP of 131.

5. Triacylglycerol synthesis occurs in the:

1. Liver
2. RBC
3. Adipocytes
4. Renal cells
5. Lactating mammary gland
6. Intestinal cells

a. 1,3,4,6 b. 1,3,5,6 c. 1,3,4,5 d. 1 only e. all of the above

6. Phospholipids are composed of the following:
1. alcohol group
2. phosphate
3. fatty acid
4. carboxyl group
5. amide
6. FeSO4

a. 3 and 6 b. 3 and 5 c. 1,2,3,6 d. 1,2,3 e. all of the above

7. The following statements are true EXCEPT:

a. Phosphatidylglycerol occurs in relatively large

amounts in mitochondrial membranes and is a
precursor of cardiolipin
b. The carbohydrate portion of a glycolipid is the
antigenic determinant
c. Glycolipids are molecules that contain both
carbohydrate and lipid components.
d. Ceramide s play a key role in ma inta ining the
skin’s water-permeability barrier.
e. Phosphatidylserine serves as a reservoir of
arachidonic acid in membranes and provides the
substrate for prostaglandin synthesis

8. Ezetimibe, a drug that prevents increased

cholesterol, has which of the following mechanism of
action?
a. It targets the Niemann-Pick C1-like 1 protein
(NPC1-L1)
b. It acts as competitive inhibitors of HMG CoA
reductase
c. It binds to bile salts in the gut; prevent their
reabsorption