0Name: ___________________________________________________ Date: ___________________________

1. A 65 year old diabetic male with a 15 year history of poorly controlled DM seeks consult for constantly feeling
fullness even after only a few bites. This is occasionally accompanied by nausea or abdominal pain. He otherwise
feels fine. An ultrasound was done which reveals normal findings. He was finally diagnosis with diabetic
gastroparesis. What is the drug of choice for this condition?
A. Metoclopromide B. Ranitidine C. Omeprazole D. Lactulose E. Senna concentrate

2. A newly diagnosed diabetic patient came to the emergency room because of 1 week history of frequent light
headedness, cold sweats and palpitations occurring 2 hours after taking an unknown medication given to him by his
neighbor for diabetes. Which is the most likely medication given to the patient?
A. Sulfonylurea B. Biguanide C. Alpha glucosidase inhibitor
D. Thiazolidinedione E. PPD4 inhibitor

3. Criteria used in the diagnosis of DM can be either of the following, except:

A.HbA1C >or =7.0% B. FPG >or =7.0 mmol/L C. OGTT 2 hour plasma glucose >or =11.1 mmol/L
D. Random plasma glucose >or=11.1 mmol/L + classic symptoms of hyperglycemia/hyperglycemic crisis
E. None

4. It is a group of disorders characterized by insulin resistance, impaired insulin secretion and excessive hepatic
glucose production (with still some insulinsecretion):
A. Type 1 DM B. Type 2 DM C. Central Diabetes Insipidus
D. Nephrogenic Diabetes Insipidus E. None of the above

5. Which of the following drugs is LEAST likely to cause hypoglycemia in a diabetic patient?
A. metformin B. gliclazide C. glibenclamide D. repaglinide E. Nateglinide

6. In the management of diabetic ketoacidosis, what condition can potentially withold the administration of insulin?
A. Hypernatremia B. Hypokalemia C. Metabolic acidosis
D. Impaired mental status E. Severe hyperglycemia

7. Which of the following is not part of the treatment goals in diabetes mellitus according ADA?
A. HBA1c <6.5% B. TAG <130mg/dl C. BP <120/80mmHg D. HDL >60mg/dl. E. All of the above

8. True regarding diabetic ketoacidosis, except:

A. fluid deficit is often 3-5 L
B. Insulin deficiency & glucagon excess are necessary for its development
C. Inadequate fluid intake is the underlying cause
D. initial intravenous fluid replacement: 0.9% NSS
E. Bicarbonate replacement is not necessary.

9. A 55 year old male, both diabetic and hypertensive, has chronic renal failure due to diabetic nephropathy. Which of
the following findings will most likely also be present in the patient?
A. Absence of proteinuria B. Contracted small kidneys on ultrasound
C. Diabetic retinopathy D. Red cell casts in the urine sediment

10. What is the most common form of diabetic neuropathy?

A. Proximal symmetric polyneuropathy B. Proximal asymmetric polyneuropathy
C. Distal symmetric polyneuropathy D. Distal asymmetric polyneuropathy E. None
11. The following are characteristics of a Type I Diabetes mellitus, EXCEPT:
A. Islet Amyloid Deposit on histology
B. Associated with HLA system
C. Severe Glucose intolerance
D. Decreased C-peptide levels
E. Weak genetic predisposition

12. Which of the following statements about insulin synthesis and secretion is not true?
A. Blood glucose level of >70 mg/dl stimulates insulin synthesis.
B. Glucose phosphorylation by glucokinase is the rate-limiting step in glucose-regulated insulin secretion.
C. Glucose is transported to the pancreatic beta cells by an active glucose transport.
E. None of the above

13. Idiopathic pancreatic beta cell destruction which leads to absolute insulin deficiency is classified as:
A. DM type 1a B. DM type 1b C. DM type 2 D. MODY type 2

14. Patient presents with polyuria, polydipsia, and weight loss. If you are suspecting diabetes mellitus, which of the
following will confirm your diagnosis.
A. HBA1C of 6% B. FBS of 6.9mmol/L C. 2-hour plasma glucose during an OGTT is 220mg/dl
D. Random blood sugar of 11mmol/L E. any of the choices

15. Metabolic syndrome refers to metabolic abnormalities that confer an increased risk of cardiovascular disease and
diabetes mellitus. Which of the following does not meet the criteria for metabolic syndrome?
A. Waist circumference of >88cm in a female
B. Triglyceride >100mg/dL
C. HDL <40mg/dL and <50mg/dL in a male and female, respectively
D. BP of 140/90mmHg
E. Fasting blood glucose of 150 mg/dL

16. The following are chronic macrovascular complications of diabetes mellitus, except:
A. Diabetic ketoacidosis B. Retinopathy C. Neuropathy D. Nephropathy E. All of the above

17. Minda, 36 year old G2P1 25 weeks AOG, come to your clinic for follow up check up. You diagnosed her to have
gestational diabetes last month for which you prescribed Metformin 500mg tab once a day. You want to know the
glycemic status over the prior 2 weeks. What test should you request?
A. FBS B. 2 hour OGTT C. Random blood sugar D. HbA1C E. Fructosamine assay

18. A patient was brought to the emergency room by a bystander because of loss of consciousness. His blood sugar
was 30mg/dl. Insulin level was high and C-peptide level was low. The patient gained consciousness after IV glucose
infusion. Which among the following statements is true regarding the cause of hypoglycemia in this patient?
A. It is most likely caused by exogenous insulin injection
B. It is caused by intake of glibenclamide, a sulfonylurea that stimulates the pancreas to secrete insulin
C. The patient has insulinoma, a tumor of the pancreas that secretes excessive amounts of insulin
D. It is most likely due to intake of metformin, an insulin sensitizer that promotes uptake of glucose into cells
E. Both A and B can be a possible cause of the patient's hypoglycemia