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Maternity blues in Athens, Greece:
A study during the first 3 days after delivery
F. Gonidakis a,⁎, A.D. Rabavilas b , E. Varsou a , G. Kreatsas c , G.N. Christodoulou d
a
Department of Psychiatry, Athens University Medical School, Greece
b
University Mental Health Research Institute, Athens, Greece
c
2nd Department of Obstetrics and Gynaecology, Athens University Medical School, Greece
d
Athens University Medical School, Greece
Received 14 April 2006; received in revised form 23 August 2006; accepted 23 August 2006
Available online 29 September 2006
Abstract
Background: Although maternity blues have been studied in many countries worldwide the factors that influence the occurrence of
this clinical entity are not well understood. The purpose of this study was to investigate the prevalence, time course and
symptomatology of maternity blues in a Greek urban environment as well as the relation of maternity blues with certain clinical and
sociodemographic factors.
Method: A study of a sample of 402 women that were recruited during the first day after delivery. Each woman completed the
Kennerley's Blues Questionnaire on a daily basis for the first 3 days of puerpartum. Clinical and sociodemographic data were
obtained through questionnaires and personal interview.
Results: 179 (44.5%) women experienced severe maternity blues during the first 3 days after delivery. Delivery by caesarian
section (P = 0.006), stressful events during pregnancy (P = 0.02), depressive feelings the last month prior to delivery(P = 0.002),
anxiety on the day of delivery (P = 0.001) and hypochondriasis (P = 0.001) were the factors that were found to relate significantly to
maternity blues.
Conclusion: The women's emotional condition prior and after delivery, delivery via caesarotomy, as well as fears concerning
somatic health had strong impact on the occurrence of maternity blues.
© 2006 Elsevier B.V. All rights reserved.
3. Results
(1970) that consists of two 20-item subscales mea-
suring anxiety as state (STAI-1) and trait (STAI-2). 3.1. Response rate and sample characteristics
The scale has been translated and validated for the
Greek language (Liakos and Giannitsi, 1984). 43 of the total 445 women were excluded from the
c) The Whitley Index (WI) is a 14-item self-rating scale study giving a response rate of 90.3%. 20 of the 43 women
produced by Pilowski (1967) for the measurement of (46.5%) could not read in Greek (all 20 women were
hypochondriasis. immigrants), 12 (28%) refused to participate, 4 (9.3%)
d) The revised Schalling–Sifneos Personality Scale gave birth to a child who faced serious medical problem, 4
(SSPS) (Sifneos, 1986) is a 20-item self-rating scale (9.3%) were found suffering from depression in day 1
for the measurement of alexithymia. (MADRS N 20), 2 (4.6%) were suffering from a chronic
e) The Maudsley Obsessive–Compulsive Inventory somatic disease (Hepatitis C caused by iv heroin use and
(MOCI) is a 30-item self-rating scale that was created diabetes mellitus under treatment with insulin) and finally
by Hodgson and Rachman (1977). It consists of 1 (2.3%) woman was excluded because she was suffering
4 subscales: checking, inhibition, doubts and cleaning. from schizophrenia and was under treatment with
f) The List of Threatening Experience (LTE) is a 12-item antipsychotic medication. There were no statistically
scale of stressful life events created by Brugha et al. significant differences in demographic and clinical data
(1985) that have been used successfully in puerpartum between the group of women that participated in the study
studies (Yamashita et al., 2000; Yoshida et al., 1997). and the group that was excluded (Table 2).
The same procedure that was followed with the B.Q. Table 1 summarizes the sample characteristics.
for the translation and adjustment of the scale in the
Greek language has also been followed with LTE. 3.2. Incidence and timing of the maternity blues
h) The Montgomery–Asberg Depression Rating Scale
(MADRS) (Montgomery and Asberg, 1979) is a When the cutoff point of 8 was applied, 93 women
semi-structured 10-item scale. The MADRS focuses (23.1%) experienced severe maternity blues during the
more to the psychic manifestations of depression first day after delivery, 87 (21.6%) during the second
rather on the somatic ones and thus is more suitable day and 107 (26.6%) during the third day. During the
Fig. 2. Day-by-day percentage of women that scored positively in each symptoms cluster of Blues Questionnaire.
whole first 3 days of puerpartum 179 women (44.5%) in day 7 the mean score was much lower (mean = 4.24 S.D. =
total experienced severe maternity blues. The 7th day 4.47). One-way repeated measures ANOVA of the four
after delivery 382 (95%) of the 402 women were measurements indicated that there were significant
reached through telephone interviews. 66 (17.3%) of differences of the BQ scores over the week of observation
them were still experiencing severe maternity blues. (Wilks' Lambda: F = 41.1, df = 3, P b 0.001).
The analysis of the daily mean scores indicated that Contrary in the NMB group the B.Q. mean score
there were different time patterns between the blues (MB) decreased significantly from day 1 (mean = 3.99, S.D. =
and the non-blues (NMB) groups. The time patterns are 1.63) to day 2 (mean = 3.30, S.D. = 1.47, two-tailed t-
presented in Fig. 1. In the MB group the BQ mean score test = 4.7, P = 0.001). There was no difference between
increased significantly in day 3 (mean = 8.72, S.D. = 4.69) day 2 and day 3 (mean = 3.42, S.D. = 1.65, two-tailed t-
compared to the mean scores of day 1 (mean = 7.70, S.D. = test = − 0.8, P = 0.4). In day 7, the mean score was lower
3.85, two-tailed t-test = − 00.2, P = 0.03) and day 2 (mean = 3.19, S.D. = 4.2). One-way repeated measures
(mean = 7.42, S.D. = 3.96, two-tailed t-test = − 0.3, ANOVA of the four measurements indicated that there
P = 0.005). There was no difference between the mean were also significant differences of the BQ scores
scores of days 1 and 2 (two-tailed t-test = 0.5, P = 0.5). In (Wilks' Lambda: F = 8.9, df = 3, P b 0.000).
112 F. Gonidakis et al. / Journal of Affective Disorders 99 (2007) 107–115
Table 3 (mean scores: 8.21, 8.12, 9.12, 4.12 for the 1st, 2nd, 3rd
Demographic, medical and data concerning pregnancy, delivery and and 7th days, respectively) and the NMB group (mean
puerperium: (a) scale and (b) nominal variables
scores: 3.99, 3.20, 3.12, 2.97 for the 1st, 2nd, 3rd and
(a) Scale variables 7th days respectively).
MB NMB t-test
group group 3.3. Clusters of symptoms
t df P
(mean (mean
score) score)
The time course for each of the 7 clusters of symp-
Demographic and social variables
toms is presented in Fig. 2. Depression was the least
Age 28.9 29.4 0.9 400 0.4
Years of education 12.6 12.5 − 0.4 400 0.7 often scored cluster followed by Reservation. On the
Years of marriage 3.7 4.7 2.7 400 0.008 contrary, Hypersensitivity and Retardation were the
Husband's age 33.9 33.9 − 0.4 400 0.9 most often scored clusters followed by Despondency,
Husband's years of education 12.5 12 − 1.2 400 0.2 Decreased Self-Confidence and Primary blues.
Medical data
Number of previous 0.2 0.4 1.9 400 0.007 3.4. Demographic, medical and data concerning
stillbirths pregnancy, delivery and puerpartum
Number of previous births 0.6 0.7 0.4 400 0.7
Number of abortions 0.4 0.3 − 0.8 400 0.4 a) Demographic and social variables: The maternity
Smoking during pregnancy 5.1 5.3 0.1 400 0.9
blues group (M.B.) differed significantly from the
(cigarettes/day)
non-maternity blues group (NMB) only in the mean
(b) Nominal variables score of the years of marriage (MB = 3.7, NMB = 4.7)
MB NMB Chi square test b) Medical variables: No differences were found
group group between the two groups.
χ2 df P
c) Pregnancy and delivery: Caesarian section was more
Demographic and social variables frequent (47% vs. 31%) in the MB group
Marital status (married) 96.1% 97.3% 0.6 1 0.7
c) Puerpartum: Women in the MB group reported more
Evaluation of marriage 8% 6% 0.9 2 0.6
(average/poor) often (14.6% vs. 6.3%) than those in the NMB group
Occupation (housewives) 30.8% 27.8% 4.7 1 0.1 that they did not intend to breastfeed and also 1 week
Nationality (Greek) 62.6% 67.6% 1.3 1 0.3 after delivery that they were not breastfeeding
(24.6% vs. 15.7%) (Table 3a,b).
Medical data
Treatment for 11% 8% 1.1 1 0.3
conceiving difficulties 3.5. Clinical measurements
Pregnancy and delivery The MB group scored higher than the NMB group in
Unwanted pregnancy 17.3% 11.7% 2.6 1 0.1 all the scales with the exception of SSPS and the
Negative mother's reaction 22.3% 18.8% 2.3 2 0.5
checking and inhibition subscales of MOCI. The most
at the announcement
of pregnancy significant differences were observed with STAI 1 (state
Mother's satisfaction 72.6% 78.9% 2.2 1 0.1
with the infants sex Table 4
Method of deliver 46.9% 30.9% 10.8 1 0.001 Clinical measurements
(caesarian section) MB group NMB group t-test
addition, some studies found no relation at all between OCD symptomatology has been found to worsen
breastfeeding and MB (Hau and Levy, 2003; O'Hara during pregnancy and puerperium (Abramowitz et al.,
et al., 1991). In our study it was not only breastfeeding 2003). The MB group was found to have higher scores
but also intention to breastfeed that differed between in the MOCI total and two of the MOCI subscales
MB and NMB group. Since breastfeeding was not found (doubt and cleaning) but regression analysis did not
in regression analysis to have a significant impact on indicate that obsessionality, as measured by MOCI, had
maternity blues our hypothesis was that it might be any influence on the development of MB.
indirectly related to maternity blues through anxiety The third personality trait that was investigated was
and/or depressive feelings. Looking back at our data we alexithymia. Alexithymia is characterized by difficulties
found that women who were not willing to breastfeed in differentiating one's feelings and verbally expressing
had higher scores on STAI (state) (t-test = 4.1, P = 0.001) them (Kooiman, 1998). How would a woman who is
and MADRS (t-test = 0.2, P = 0.09) than women who facing difficulties expressing her feelings would react to a
intended to breastfeed. situation were everyone would expect her to be emotional;
The third aim of our study was to investigate the Alexithymia has never been studied in women that
relation of maternity blues with depressive feelings and develop maternity blues. Our hypothesis that alexithymia
stressful life events prior to delivery and stress at the day might relate with MB was based on the relation between
of delivery. Unfortunately the evaluation of the first two alexithymia and physical symptoms (Kooiman, 1998),
factors was done respectively as women were asked to depression (De Gennaro et al., 2004) as well as panic
describe how they were feeling during the last month attacks (Marchesi et al., 2005). Alexithymia measure-
of their pregnancy after they had delivered their baby. This ments did not differ between the MB and NMB group thus
limitation was due to the fact that most of the women were failing to verify our hypothesis.
not followed up during pregnancy in the obstetric clinic To conclude, our study tried to offer a better under-
and they were admitted to the maternity ward on the day standing of maternity blues in a Southern European
of delivery. Stressful life events during pregnancy have cultural environment. This study indicates that maternity
been reported in the literature to relate to the development blues are experienced by women in Greece in similar
of maternity blues (Pop et al., 1995; O'Hara et al., 1991). frequency and timing, regardless of family support but
Depression and anxiety during pregnancy have also been maybe through different symptoms than in Northern
reported as factors that have a strong influence on the European countries. Also according to the results of this
development of the blues. Murata et al. (1998) reported study anxiety and depressive feelings measured on the
that poor emotional condition prior to pregnancy was day of delivery as well as stressful life events during
related with depressive emotions after delivery. Similar pregnancy and hypochondriac fears seem to have a
results have been reported by Hensaw (2003) and strong impact on the development of the blues. The
Adewuya (2005). It is noteworthy that even when relation of maternity blues and caesarian section should
women that scored higher than 20 in the MADRS were alert obstetricians especially in Greece where around one
excluded the MADRS score was still related to the third of women deliver through surgery.
occurrence of maternity blues.
Finally the fourth aim of our study was to investigate References
the relation of maternity blues to personality traits. We
chose hypochondriasis and obsessionality on the
Abramowitz, J.S., Schwartz, S.A., Moore, K.M., Luenzmann, K.R.,
hypothesis that admission to a hospital, having respon- 2003. Obsessive–compulsive symptoms in pregnancy and the
sibility of a newborn baby, staying in a ward with other puerperium: a review of the literature. J. Anxiety Disord. 17 (4),
women and using kitchen utilities and toilets other than 461–478.
their own would stress heavily hypochondriac and Adewuya, A.O., 2005. The maternity blues in Western Nigerian
obsessive women. women: prevalence and risk factors. Am. J. Obstet. Gynecol. 193
(4), 1522–1525.
Murata et al. (1998) reported a relation between the Bergant, A.M., Heim, K., Ulmer, H., Illmensee, K., 1999. Early
blues and the hypochondriasis subscale of MMPI. Our postnatal depressive mood: associations with obstetric and
results support our hypothesis that women that worry psychosocial factors. J. Psychosom. Res. 46 (4), 391–394.
about their physical health are more prone to develop Brugha, T., Bebbington, P., Tennant, C., Hurry, J., 1985. The list of
maternity blues. Similar results concerning the relation threatening experiences: a subset of 12 life event categories with
considerable long term contextual threat. Psychol. Med. 15, 189–194.
between maternity blues and catastrophizing labour pain De Gennaro, L., Martima, M., Curcio, G., Ferrara, M., 2004. The
but not labour pain itself have been recently reported by relationship between alexithymia, depression and sleep com-
Ferber et al. (2005). plaints. Psychiatry Res. 128 (3), 253–258.
F. Gonidakis et al. / Journal of Affective Disorders 99 (2007) 107–115 115
Ehlert, U., Pattala, U., Kirschbaum, C., Piedmont, E., Hellhammer, D.H., Nappi, R., Petraglia, F., Luisi, S., Polatti, F., Farina, C., Genazzani, A.,
1990. Postpartum blues: salivary cortisol and psychological factors. 2001. Serum allopregnanolone in women with postpartum. Blues
J. Psychosom. Res. 34 (3), 319–325. Obst. Gynaecol. 97 (1), 77–80.
Ferber, S.G., Granot, M., Zimmer, E.Z., 2005. Catastrophizing labor Pilowski, I., 1967. Dimensions of hypochondriasis. Br. J. Psychiatry
pain compromises later maternity adjustments. Am. J. Obstet. 134, 382–389.
Gynecol. 192 (3), 826–831. Pitt, B., 1973. Maternity blues. Br. J. Psychiatry 122, 431–433.
Hannah, P., Adams, D., Lee, A., Glover, V., Sandler, M., 1992. Links Pop, V.J., Wijnen, H.A., Van Montfort, M., Essed, G.G., De Geus, C.A.,
between early post-partum mood and postnatal depression. Br. J. Van Son, M.M., Komproe, I.H., 1995. Blues and depression during
Psychiatry 160, 777–780. early puerperium: home versus hospital deliveries. Br. J. Obstet.
O'Hara, M., Schlechte, J., Lewis, D., Wright, E., 1991. Gynaecol. 102, 701–706.
Prospective study of postpartum blues. Arch. Gen. Psychiatry Rodhe, L.A., Busnello, E., Wolf, A., Zomer, A., Shansis, F., Martins,
48, 801–806. S., Tramontina, S., 1997. Maternity blues in Brazilian women.
Harris, B., 1981. Maternity blues in East African clinic attenders. Arch. Acta Psychiatr. Scand. 9, 231–235.
Gen. Psychiatry 38, 1293–1295. Savage, G., 1875. Observations on the insanity of pregnancy and
Hau, F., Levy, V., 2003. The maternity blues and Hong-Kong Chinese childbirth. Guy's Hosp. Rep. 20, 83–117.
women: an exploratory study. J. Affect. Disord. 75, 197–203. Sifneos, P., 1986. The Schalling–Sifneos Personality Scale revised.
Hensaw, C., 2003. Mood disturbances in the early puerperium: a Psychother. Psychosom. 45, 161–165.
review. Arch. Womens Ment. Health 6 (suppl 2), S33–S42. Spielberger, C.D., Gorsuch, R.L., Lushene, R.E., 1970. Manual for the
Hodgson, R.J., Rachman, S., 1977. Obsessional–compulsive com- State–Trait Anxiety Inventory. Consulting Psychologists Press,
plaints. Behav. Res. Ther. 15, 389–395. Palo Alto, CA.
Iles, S., Gath, D., Kennerley, H., 1989. Maternity blues: II. A Sutter, A.L., Leroy, V., Dallay, D., Verdoux, H., Bourgeois, M., 1997.
comparison between post-operative women and postnatal women. Post partum blues and mild depression symptomatology at
Br. J. Psychiatry 155, 363–366. days three and five after delivery. A French cross sectional
Kennerley, H., Gath, D., 1989. Maternity blues: I. Detection and study. J. Affect. Disord. 44, 1–4.
measurement by questionnaire. Br. J. Psychiatry 155, 356–362. Taylor, A., Littlewood, J., Adams, D., Dorė, C., Glover, V., 1994.
Kooiman, C.G., 1998. The status of alexithymia as a risk factor in Serum cortisol level is related to mood of elation and dysphoria in
medically unexplained physical symptoms. Compr. Psychiatry 39 new mothers. Psychiatry Res. 54 (3), 241–247.
(3), 152–159. Thalassinos, M., Zittoun, C., Rouillon, F., Engelmann, P., 1993.
Lanczik, M., Spingler, H., Heidrich, A., Becker, T., Kretzer, B., Albert, Anxiety and depressive disorders in the postpartum period in
P., Fritze, J., 1992. Post partum blues: depressive disease or pregnant females. J. Gynecol. Obstet. Biol. Reprod. 22 (1),
pseudoneurasthenic syndrome? J. Affect. Disord. 25 (1), 47–52. 101–106.
Levy, V., 1987. The maternity blues in post-partum and post-operative Thorpe, K.J., Dragonas, T., Golding, J., 1992. The effects of
women. Br. J. Psychiatry 151, 368–372. psychosocial factors on the mother's emotional well being during
Liakos, A., Giannitsi, S., 1984. The validity of the revised Greek early parenthood: a cross-cultural study of Britain and Greece.
Spielberger State Train Anxiety Inventory. Encefalos 21, 71–76 J. Reprod. Infant Psychol. 10, 205–216.
(in Greek). Tsukasaki, M., Ohta, Y., Oishi, K., Miyaichi, K., Kato, N., 1991. Types
Marchesi, C., Fonto, S., Balista, C., Cimmino, C., Maggini, C., 2005. and characteristics of short-term course of depression after
Relationship between alexithymia and panic disorder: a longitu- delivery: using Zung's Self-Rating Depression Scale. Jpn. J.
dinal study to answer an open question. Psychother. Psychosom. Psychiatry Neurol. 45 (3), 565–576.
74 (1), 56–60. Yalom, I., Lunde, D.T., Moos, R.H., Hamburg, D.A., 1968.
Moloney, J., 1952. Post partum depression or third day depression Postpartum blues syndrome. Arch. Gen. Psychiatry 18 (1), 16–27.
following childbirth. New Orleans Child Parent Digest. 6, 20–32. Yamashita, H., Yoshida, K., Nakano, H., Tashiro, N., 2000. Postnatal
Montgomery, S.A., Asberg, M., 1979. A new depression scale depression in Japanese women. Detecting the early onset of
designed to be sensitive to change. Br. J. Psychiatry 134, 382–389. postnatal depression by closely monitoring the postpartum mood.
Murata, A., Nadaoka, T., Morioka, Y., Oiji, Saito, H., 1998. Prevalence J. Affect. Disord. 58, 145–154.
and background factors of maternity blues. Gynecol. Obstet. Yoshida, K., Marks, M.N., Kibe, N., Kumar, R., Nakano, H., Tashiro,
Investig. 46, 99–104. N., 1997. Postnatal depression in Japanese women who have giver
Nagata, M., Nagai, Y., Sobajima, H., Ando, T., Nishide, Y., Honjo, S., birth in England. J. Affect. Disord. 43, 69–77.
2000. Maternity blues and attachment to children in mothers of full
term normal infants. Acta Psychiatr. Scand. 101 (3), 209–217.