UNIVERSITI TUNKU ABDUL RAHMAN ACADEMIC YEAR 2012/2013 APRIL EXAMINATION FHSBI214 BIOLOGY I TUESDAY, 23 APRIL 2013 TIME: 9.00 AM ~ 11.00 AM (2 HOURS) FOUNDATION IN SCIENCE. This question paper consists of 4 questions on 12 printed pages.FHSB1214 BIOLOGY 1 Ql. (@) During a Biology practical class, the students were provided with solution A. They added an equal volume of 5% sodium hydroxide solution to solution A. Next, they added in few drops of 1% copper sulphate solution into the mixture of solution A and 5% sodium hydroxide. The purpose of these procedures is to detect the presence of biomolecules with peptide bonds. They observed that the solution tumed into purple. ) Identify the class of biomolecule that is present in solution A. (1 mark) Draw the monomer of biomolecule in solution A. (2 marks) A student accidentally heated solution A before performing the steps mentioned above, (A) Predict whether purple coloration will be observed. (1 mark) (B) Explain your answer in part (A) above, (2 marks) (b) Sucrose is the organic compound commonly known as table sugar or saccharose. Figure 1.1 shows the structure of sucrose and the process in which sucrose is, broken down into its monomers. ee oo o a Fl eee, one 5a "ans 4° wa veo, -2_| vom Son K so Kl on Figure 1.1 a Identify monomer X, monomer Y and process A. (3 marks) (i) When Benedict test was performed on sucrose, it was observed that the blue colour remained unchanged. Make a conclusion based on this observation. (1 mark) This question paper consists of 4 questions on 12 printed pages:FHSB1214 BIOLOGY I QL.) (Continued: (ii) Monomers X can undergo process B to form polysaccharide P. This polysaccharide can exist in two forms as shown in Figure 1.2. “Be B etn & ere & S$ 3 Polysaccharide P Figure 1.2 (A) Identify polysaccharide P, (marke) (B) Suggest ONE function of polysaccharide P. (1 mark) (©) Compare polysaccharide P and cellulose in terms of their structure, Copy Table 1.1 and write the answers in your answer booklet (4 marks) Table 1.1 Polysaccharide P [Cellulose ‘Monomer (specific name) Branching | (present/absent) Shape Cross linkage Wabsent) (ore This question paper consists of 4 questions on 12 printed pages.FHSB1214 BIOLOGY I QL. (Continued) (©) Lipase is an enzyme that can digest lipids. An experiment was set up to study the effect of temperature on the action of lipase enzyme. Nine test tubes were prepared separately and the experimental set up was designed in a way as shown in Figure 1.3. The nine test tubes which contain 10cm’ of com oil and lem’ of lipase were kept at a range of temperatures between 20°C and 100°C. When experiment starts, the pH of the contents in each test tube was constant, which was 6.5. thermomete | ~~ oy pH meter _--— water bath —-— test tube Figure 1.3 Each test-tube was left for 30 minutes and the reading on the digital pH meter vyas then recorded. The pH readings against different temperatures are plotted in a graph, shown in Figure 14 s om Cr ar) fest test test test tast_ test fast teat tt tube tube 2 tube's— bed tubes tube tube oe 8 tube Temperature "<) Figure 14 “his question paper consists of 4 questions on 12 printed pages.FHSB1214 BIOLO’ QL.(c) (Continued) i ai) ii) i) 2 @ State the products of hydrolyzed com oil (2 marks) With reference to Figure 1.4, state the optimum temperature for lipase to perform its catalytic activity. (1 mark) Briefly explain how lipase activity at this optimum temperature leads to the respective pH in Figure 1.4 (2 marks) Explain why the pH did not change between 80°C and 100°C at the end of the experiment. (4 marks) [Total: 25 marks] In fluid mosaic model, the cell membrane can be viewed as two dimensional solutions of oriented lipids and globular proteins. All cells are enclosed by the plasma membrane in order to differentiate its composition from the surroundings, a) w Gii) Provide ONE terminology that could be used to replace the underline words. (1 mark) Name the globular protein which involved in cell-cell recognition. Briefly explain the importance of this protein. (2 marks) The biomoleeules that found in the cell membrane enable the cell to regulate the chemical exchanges with the environment. Do you agree with this statement? Provide ONE explanation to support your answer. (2 marks) This question paper consists of 4 questions on 12 printed pages.FHSB1214 BIOLOGY I Q2. (Continued) () © Figure 2.1 shows four ways in which molecules may move into an animal cell and out of an animal cell aerobically. The dots show the concentration of molecules. Figure 2.1 State the correct letter, A, B. C or D, to the following processes. (The movement of oxygen molecules. (1 mark) Gi) The movement of carbon dioxide molecules. (1 mark) Gi) The active uptake of glucose molecules. (1 mark) (iv) Based on the answer given in (b) (iii), explain your answer, (2 marks) May is having loose or liquid defecation more than three times in a day. She feels thirsty with dry skin, weak and tired. Doctor diagnosed that she is suffering from diarrhea, Dehydration and exhaustion are the common effects of diarthea. Based on your understanding about the cell tonicity of the blood cells, relate ciarthea with the physical condition of May (5 marks) This question paper consists of 4 questions on 12 printed pages.FHSB1214 BIOLOGY 1 Q2. (Continuec) @ ai) Gi ) Figure 2.2 Identify the structures labeled as B, C and F, G marks) ‘Name ONE substance that is represented by E. (1 mark) Refer to Table 2.1, compare the structural differences between organelle Aand D. Copy Table 2.1 and write the answers in your answer booklet. (4 marks) Table 2.1 A D Membrane Ribosomes | Suggest a structure that facilitates the movement of structure F from organelle D towards plasma membrane and briefly describe how the movement is brought about (2 marks) [Total: 25 marks] This question paper consists of 4 questions on 12 printed pages.FHSB1214 BIOLOGY I Q3. (a) Figure 3.1 shows the structure of @ mitochondrion, Figure 3.1 (@ Identify structure X in Figure 3.1 and state TWO components that could be found in this region, G marks) (State and briefly explain the adaption of structure Y that could enhance the function of mitochondrion in generating ATP, (2 marks) (&) A simple respirometer, such as that shown in Figure 3.2, has been set up to study the respiration of germinating mung beans, coloured Plunger 1dB menieus bagot germinating sodelime mung beans Figure 3.2 (State the purpose of soda lime in this experimental set up, (1 mark) ii) Give the chemical equation for the cellular aerobic respiration, (2 marks) ‘At the end of this experiment, explain why the coloured water as the indicator has been moved inward. (3 marks) questions on 12 printed pages. ‘This question paper consists o'FHSBi214 BIOLOGY I Q3. (Continued) © i) State the meaning of respiratory quotient (RQ). You may write the ‘meaning in an equation form. (2 marks) The following equation demonstrates the aerobic respiration of the respiratory substrate A, Ciglis602 + 2602 ——> 18120 + 18.CO2 + energy Calculate the respiratory quotient (RQ) of this respiratory substrate. 2 marks) (@) Figure 3.3 outlines anaerobic respiration in yeast cells. oO (i) Gi) (iv) glucose v pyruvate oS product P N Figure 3.3 Identify the components labelled as L, M, N and P. (4 marks) Name the process occurs in Figure 3.3. (I mark) Describe how anaerobic respiration in mammalian cells differs from anaerobic respiration in yeast cells, (2 marks) Anaerobic respiration results in a small yield of ATP compared with aerobic respiration. Provide THREE reasons to support this statement. (3 marks) (Total: 25 marks] ‘question paper consists of 4 questions on 12 printed pages.10 4 BIOLOGY I Q4. (a) Figure 4.1 shows two pairs of homologous chromosomes during meiosis. The letters represent chromosomes. At the end of meiosis, four possible chromosomal combinations can be produced, Figure 4.2 shows the distribution af chromosomes from Figure 4.1 into the gamete cells my At ‘Pa Bt {i} Be Figure 4.1 eS Combination 1 Combination 2 Combination 3. Combination 4 A1&B1 A2 & B2 A1&B2 A2&B1 Figure 4.2 @ With reference to Figure 4.1 and Figure 4.2, name the Mendelian law involved and briefly describe how the daughter cells with different combinations of chromosomes are produced. G marks) (i) Briefly describe the roles of mitotic spindle in chromosomal movements during mitosis (3 marks) This question paper consists of 4 questions on 12 printed pagesFHSB1214 BIOLOGY I Q4. (Continuec’ () © Familial hypercholesterolemia is an inherited trait manifested as markedly elevated total serum cholesterol levels and early coronary heart disease. Figure 43 is a pedigree tree showing the inheritance of this disorder. Affected individuals are highlighted in black, which are coded with numbers 2, 5, 6, 13, and 14. ® wi) Gi) yy Male Oremate Identify the mode of inheritance of this disorder. (autosomal dominan/autosomal recessive?) (1 mark) Figure 4.3 With reference to Figure 4.3, state the evidence to support your answer in VA). (2 marks) Using letter H to represent dominant allele and letter h to represent recessive allele, state the possible genotype for individual 1 and 6 (2 marks) Individual 6 is married with an unaffected woman, Using a Punnett square, calculate the probability that their first child is affected and second child is normal (4 marks) In peas, a gene for tall plants (4) is dominant over its allele for short plants (a). ‘The gene for smooth peas (B) is dominant over its allele for wrinkled peas (6). The ger snes are not linked. A short plant with smooth peas is mated with a tall plant with wrinkled peas and the following F; plants are obtained. 53 tall plants with smooth peas 48 short plants with smooth peas 49 tall plants with wrinkled peas 47 short plants with wrinkled peas (i) State the genotypes of the parents. (2 marks) Gi) Use a Punnett square to show how the results of F; plants are obtained. G marks) This question paper consists of 4 questions on 12 printed pages. -2 FHSB1214 BIOLOGY I Q4. (Continued! (@) Given that organism A has 4 chromosomes in a gamete cell. A diploid cell undergoes meiosis to produce gamete cells, State the number of chromosomes and sister chromatids in each cell at the end of the stated stages. Copy Table 4.1 into your answer booklet and fill in the answers. (5 marks) : Table 4.1 Stage Number of | Number of sister | chromosomes | chromatids G phase of interphase 8 ‘Anaphase I 8 | Telophase | & cytokinesis | I ‘Anaphase 1 a (Total: 25 marks} END OF PAPER is question paper consists of 4 questions on 12 printed pages.