PMID- 28329470

OWN - NLM
STAT- MEDLINE
DCOM- 20171011
LR - 20171011
IS - 1087-2108 (Electronic)
IS - 1087-2108 (Linking)
VI - 23
IP - 1
DP - 2017 Jan 15
TI - Cutaneous manifestations of disseminated gonococcemia.
LID - 13030/qt33b24006 [pii]
AB - BACKGROUND: Sexually transmitted infections, includingurogenital gonorrheal
infection, are a growing healthconcern in the United States. Nearly 50% of
cervicalinfections are asymptomatic. If left undiagnosedand untreated, there
is a
risk of disseminatedinfection. PURPOSE: To describe an 18-year-old
womanpresenting with disseminated gonococcal infectionconfirmed by blood
cultures, skin biopsy, and urinegonococcal probe. We also describe the
presentation,diagnosis, and treatment of disseminated gonococcalinfection,
including discussion of the variousmorphologies of cutaneous lesions that
have
beenreported in the literature. MATERIALS AND METHODS: Thefeatures of a woman
with disseminated gonococcalinfection are presented. Using PubMed, the
termscutaneous, disseminated, gonococcal, gonorrhea,infection, lesions,
manifestations, pustules, skin, andsystemic were searched. Relevant citations
wereutilized and discussed. RESULTS: Hemorrhagic pustules,petechiae, and
purpuric
lesions developed in a youngwoman with fever and joint pain. Blood cultures
grewbeta lactamase negative Neisseria gonorrhoeae andthe Neisseria
gonorrhoeae/Chlamydia trachomatisprobe was positive for both N. gonorrhoeae
and
C.trachomatis. Biopsy revealed bulla with neutrophils,extravasated
erythrocytes,
fibrin deposits in the vesselwalls, and leukocytoclasia. CONCLUSION:
Cutaneouslesions of disseminated gonococcal infection caninclude abscesses,
cellulitis, petechiae, purpuricmacules, necrotizing fasciitis, and
vasculitis. It
isimportant for the clinician to recognize the clinicalsigns and symptoms of
disseminated gonococcalinfection, particularly the various
cutaneousmanifestations.
FAU - Beatrous, Surget V
AU - Beatrous SV
AD - Medical School, Louisiana State University Health Sciences Center, New
Orleans.
Sbeat2@lsuhsc.edu.
FAU - Grisoli, Stratton B
AU - Grisoli SB
FAU - Riahi, Ryan R
AU - Riahi RR
FAU - Matherne, Ryan J
AU - Matherne RJ
FAU - Matherne, Ryan J
AU - Matherne RJ
LA - eng
PT - Case Reports
PT - Journal Article
PT - Review
DEP - 20170115
PL - United States
TA - Dermatol Online J
JT - Dermatology online journal
JID - 9610776
RN - 0 (Anti-Bacterial Agents)
RN - 75J73V1629 (Ceftriaxone)
SB - IM
MH - Adolescent
MH - Anti-Bacterial Agents/therapeutic use
MH - Arthritis, Infectious/*diagnosis/drug therapy
MH - Bacteremia/*diagnosis/drug therapy
MH - Ceftriaxone/therapeutic use
MH - Dermatitis/*diagnosis/drug therapy/pathology
MH - Female
MH - Gonorrhea/*diagnosis/drug therapy
MH - Humans
MH - Neisseria gonorrhoeae
EDAT- 2017/03/23 06:00
MHDA- 2017/10/12 06:00
CRDT- 2017/03/23 06:00
PHST- 2017/01/20 00:00 [received]
PHST- 2017/01/20 00:00 [accepted]
PHST- 2017/03/23 06:00 [entrez]
PHST- 2017/03/23 06:00 [pubmed]
PHST- 2017/10/12 06:00 [medline]
PST - epublish
SO - Dermatol Online J. 2017 Jan 15;23(1).