Professional Documents
Culture Documents
1
Need not be transferred from Concept:
one person to another Consider the susceptibility of
the host
Contagious Diseases Susceptibility
Diseases that can easily be o Pertains to degree of
transmitted resistance
If resistance is low,
susceptible person is prone to
Concepts: infection
All communicable diseases
are infectious but not Types of Hosts:
contagious 1.1) Patient
Because there is the A person infected manifesting
presence of a living signs and symptoms
microorganism
Because not all of the 1.2) Carrier
microorganisms can be easily Individual who harbors
transmitted microorganisms but shows no
signs and symptoms
All contagious diseases are
infectious 1.3) Suspect
Individual whose medical
All contagious diseases are history and symptoms
communicable diseases suggests that he may be
developing a specific infection
Diphtheria is a disease, which Signs and symptoms are
is suggestive
o Contagious
o Communicable 1.4) Contact
o Infectious Individuals who come in close
association or in contact or
Malaria is a disease, which is exposed to infected person
o Communicable
o Infectious Concepts:
o But not contagious The PATIENT is the least
source of infection
Tetanus is a disease, which is The PATIENT has the least
o Infectious only chance to spread
microorganisms
o Because he manifests
Epidemiological Triad
Three (3) factors for a disease to signs and symptoms of
take place the disease, he is
1. HOST isolated
A person o Precautionary
An animal measures are now
taken
2
The CARRIER has the Syphilis is not fatal in the first
highest potential to spread trimester
infection Syphilis is fatal in the third
o Because he does not trimester
manifest signs and Anti-bacterial medications
symptoms of the give only temporary immunity
disease
o However, he has the Viruses
microorganisms Can only multiply in living
things
2. AGENT Reservoir is a living thing
Microorganisms Can pass through the body
They have the highest filters:
population among all living o Blood Brain Barrier
things o Placental Barrier
Not all are susceptible to It gives rise to self-limiting
microorganisms diseases
Not all microorganisms are Viral infections have own time
virulent frame
Example:
Concepts: o Colds last for 2-3 days
Virulence with watery secretions
Strength and power of as symptoms
microorganisms to cause After this,
infection complications
Pathogenicity of microorganisms would be the
Capacity of microorganisms to one present with
cause infection yellowish or
mucoid
Two (2) most common discharges
microorganisms causing infections probably
Bacteria indicative of
Viruses sinusitis
o Influenza is present for
Bacteria one week
Can multiply in both living and After one week,
non-living things pneumonia sets
Cannot pass through filters in in.
the body because they are big Medical management for viral
Therefore, it is okay to have infections:
bacterial infection even during o Treated
pregnancy, except for symptomatically not by
Treponema pallidum, which anti-viral agents
passes through the placental o Antibiotics may be
barrier after the 16th week of used to treat secondary
pregnancy. bacterial infections
3
o Purpose is to increase 3. Portal of Exit
body resistance From the reservoir,
microorganisms look for a
3. ENVIRONMENT way out
Must be conducive and This pertains to the
favorable to growth of individual’s body system
microorganisms Examples:
Example: o T. pallidum’s portal of
o Clostridium tetani will exit is the genitourinary
not cause infection in system
the presence of oxygen o Measles’ virus portal of
because it is an exit is the respiratory
anaerobic system
microorganism o Salmonella typhosa’s
portal of exit is the
Concept: gastrointestinal tract
There must be an interplay between
the three factors: 4. Mode of Transmission
Host When outside of the host, this
Agent pertains to the
Environment microorganism’s means of
for infection to set in. transportation
Examples:
CHAIN OF INFECTIOUS PROCESS o T. pallidum’s mode of
A cycle transmission is sexual
It is continuous contact
o Measles’ virus mode of
Six (6) Factors transmission is
1. Causative agent airborne nuclei
Microorganisms o Salmonella typhosa’s
mode of transmission
2. Reservoir is fecal-oral ingestion
A place where
microorganisms can live and 5. Portal of Entry
multiply A microorganism’s way in to
Examples: the new host
o T. pallidum’s reservoir Also corresponds to the
is the human genitalia individual’s body system
o Measles virus reservoir Examples:
is the nasopharynx o T. pallidum’s portal of
o Salmonella typhosa’s entry is the
reservoir are the genitourinary system
Peyer’s patches of the o Measles’ virus portal of
small intestines entry is the respiratory
system
4
o Salmonella typhosa’s IMMUNITY
portal of entry is the State of having resistance
gastrointestinal tract State of being free from
infection
6. Susceptible Host
Concept: Two (2) Types of Immunity
Objective or goal is to limit, Natural Immunity
prevent or control spread of Acquired Immunity
communicable diseases by
breaking the chain of 1. Natural Immunity
diseases Inherent in an individual’s
Look for the weakest link in body tissues and fluids
the chain A person is born with it
Among the six (6) factors, the A person dies with it
MODE OF TRANSMISSION It is within the genes that you
is the weakest link have these antibodies
o It is not the This is a rare type of immunity
CAUSATIVE AGENT Example:
because of its huge o Race
population
o It is not the 2. Acquired Immunity
RESERVOIR (i.e. you This is the more common type
cannot remove the of immunity
nasopharynx in It is either a person is able to
humans infected by PRODUCE it or a person is
measles virus) able to GET it
o It is not the PORTAL
OF EXIT nor the Two (2) Types of Acquired
PORTAL OF ENTRY Immunity
(i.e. you cannot remove
the genitals of humans 2.1) Active Acquired Immunity
infected by T. pallidum) An actual participation of the
o It is not the individual’s body tissues and
SUSCEPTIBLE HOST fluid in PRODUCING
for you cannot kill it. immunity
You produce the antibodies
IMPORTANT CONCEPTS!!! yourself when
Typhoid mode of transmission microorganisms are given to
is fecal-oral ingestion you
First word is the PORTAL OF
EXIT Two (2) Ways of Producing
Second word is the PORTAL Antibodies:
OF ENTRY 2.1.1) Naturally Acquired Active
DO NOT INTERCHANGE Immunity
THIS!!! Antibodies are produced by
nature
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Unintentionally If the site has not dried off,
Examples: there will be VACCINE
o Previous attack of a FAILURE!
disease Therefore, squeeze off excess
o Chicken pox attack alcohol
wherein antibodies are
produced by nature 2.2) Passive Acquired Immunity
o Measles attack wherein Immunity is developed due to
antibodies are presence of antibodies within
produced by nature the serum, which is not
Sub-clinical immunity coming from the individual
o Developed due to itself
constant exposure to You get it or it is given to you
certain infection
o Body produces Two (2) Types of Passive Immunity
antibodies non- 2.2.1) Naturally Acquired Passive
intentionally by nature Immunity
that provides immunity Done by nature
Antibodies given or obtained
2.1.2) Artificially Acquired Active by nature, in an unintentional
Immunity manner
Body produces antibodies Examples:
because it was intentionally o Infants below six (6)
done months seldom
Examples: develop infection
o Vaccines o Maternal transfer of
Attenuated antibodies
(weakened) o Placental transfer of
microorganisms antibodies
o Toxoids o Infants who are breast-
Attenuated fed
toxins Colostrum
(poisonous intake
substances) Contains
produced by antibodies from
microorganisms mother given
Concepts! unintentionally
When administering vaccines
or toxoids, alcohol is NOT 2.2.2) Artificially Acquired Passive
used to clean injection site. Immunity
Use instead cotton balls with Administration of substances
a clean bowl of water. containing antibodies in an
When alcohol is used, be sure intentional manner
alcohol HAS DRIED OFF Examples:
before administration of the o Anti-toxins
vaccine or toxoid o Anti-serum
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o Gamma globulin Know the MODE OF
o Immunoglobulins TRANSMISSION
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There are only two (2) Department of Health is
PERMANENT composed of CHILDREN
CONTRAINDICATIONS to BELOW FIVE (5) YEARS
Immunization OLD
Allergy
Encephalopathy without CDT VACCINE
known cause or convulsions Cholera, Dysentery, Typhoid Vaccine
within seven (7) days after Given by DOH for free
pertussis vaccine Adult dose is 0.5 cc
administration Adult injection site is the
deltoid muscle
There are four (4) TEMPORARY Child dose is 0.25 cc
CONTRAINDICATIONS for Child injection site is the
Immunization vastus lateralis
Pregnancy Given INTRAMUSCULARLY
o (i.e. MMR vaccine) (I.M.)
Recent receipt of blood Given when there are
products outbreaks of epidemic
o Wait two (2) to three (3) Immunity lasts only for six (6)
months months.
Very severe disease
o Hospital confinement Anti-Rabies Vaccine
o Hospital personnel will Target group would be the
decide when animals
immunization would be Animals are brought to the
given Barangay for free
Immunocompromised immunization
situation Barangay Captain is
responsible for obtaining
Fever, diarrhea and colds are vaccines from DOH
NOT CONTRAINDICATIONS Dogs must initially be
to Immunization. registered before this vaccine
Immunization can still be could be administered
given despite their presence
1.3) Environmental Sanitation
In a private setting, the Objective:
physician can POSTPONE o No proliferation of
IMMUNIZATION in the arthropods, rodents
presence of fever, diarrhea, (both of which are good
colds because patient is vectors)
returned by mother to the Presidential Decree 856
physician once these Sanitation Code
conditions are resolved. Also includes submission of
Current target group of sex workers in determination
Expanded Program on of sexually transmitted
Immunization of the diseases
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o For gonorrhea – two It intends to limit the
times a month microorganisms to be within
o For syphilis – once a the patient
month
o Physical Examination – 2.1.2) Reverse Isolation
once a month Also called Protective
Isolation
Presidential Decree 825 Intended to protect the
Anti-Littering Law immunocompromised patient
Proper disposal of garbage from infection
Anyone caught littering would Intends to keep
have a penalty of Php2,000 to microorganisms out of the
Php5,000 and imprisonment patient
for one (1) year.
Concepts:
1.4) Proper Supervision of Food Quarantine
Handlers Limitation of freedom of
A responsibility of the movement of a well person
Department of Health during the longest incubation
facilitated by its Sanitary period
Inspectors It involves the separation of
Also a responsibility of the persons who are carriers
Bureau of Food and Drug These are persons who are
Monitors food and drug sold not sick
to public to assure that it is These are persons who do
safe for consumption not manifest signs and
symptoms of the disease
2. CONTROL ASPECT
Done when signs and Center for Disease Control’s two
symptoms are already present (2) Revised Isolation Precautions
There is already the presence
of infection 1) Standard Precaution
Goal is to limit the infection Best strategy to prevent
nosocomial infection
2.1) Isolation Slowly taking place of
Separation of an infected Universal Precaution
person during period of Applies to all patients
communicability regardless of their diagnosis
Applies to blood and all body
Two (2) ways of Isolation fluids, excretions and
2.1.1) Strict Isolation secretions except sweat.
Intended to protect other Applies to mucous membrane
persons (not the patient) from and non-intact skin
infection
Concept:
Universal Precaution
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Has double standards o Cap / Bonnet
Used only if patient is o Goggles
diagnosed or suspected of o Mask
having blood-borne diseases
3. Avoidance of Needle Stick or
Elements included in Standard Sharps Injury
Precautions Do not recap, bend or break
1. Practice hand washing for each needles
patient care There must be puncture-
For contact with body fluids of resistant sharps collector
patient
Duration is 10 – 15 seconds IMPORTANT CONCEPT!!!
Length of washing is not If patient is diagnosed as
important having communicable
What is important is the disease, practice both
friction that is applied Standard Precaution and
Transmission-based
Concepts: Precaution
For Medical Asepsis:
Hand is lower than the elbow Transmission Based Precaution
Hand is the dirtiest part Airborne Precaution
Elbow is the cleaner part Use of mask
Special ultrafilterable mask
For Surgical Asepsis: Particulate mask
Hand is placed up and o For measles, chicken
remains up pox, TB
Hand is the cleanest portion
Elbow is less clean than the Droplet Precaution
hands No contact to mucous
membrane, nose, mouth
2. Use of Protective Barriers or Use mask – ordinary mask
Use of Personal Protective will do
Equipment (PPEs) Use goggles
If you wear them all, the o For meningitis, mumps,
correct sequence for wearing pertussis, German
them would be: measles, diphtheria
o Mask
o Goggles Contact Precaution
o Cap / Bonnet Avoid person to person
o Gown contact
o Gloves Use gloves
If you are about to remove Use gown
them, the correct sequence is: For diarrheal diseases,
o Gloves typhoid, cholera, hepatitis,
o Do hand washing skin diseases like ringworm,
o Gown scabies and pediculosis
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Placarding
Control Measures other than o Placing “NO
Isolation SMOKING” sign when
1. Disinfection there is oxygen
Killing of pathogenic inhalation in progress.
microorganisms by physical or
chemical means (i.e. boiling, COMMUNICABLE DISEASES OF
soaking) THE CENTRAL NERVOUS
SYSTEM
Types of Disinfection
Bacterial infections
Concurrent Disinfection Tetanus
Done when the person is still Meningitis
a source of infection
Example: Viral Infections
o When patient is still in Encephalitis
the hospital Poliomyelitis
Boil all patient gowns Rabies
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into a VEGETATIVE FORM,
which can be destroyed by Two (2) Types of Toxins in Tetanus
the presence of oxygen
Why is Clostridium tetani 1. Tetanolysin
abundant in soil? Dissolves red blood cells
o Normal habitat of C. Results to anemia
tetani is in the Thus, patient is pale-looking
intestines of
herbivorous animals 2. Tetanospasmin
(i.e. cows, carabaos, Causes muscle spasm
goats, sheep, horses) Acts on MYONEURAL
o Manure of these JUNCTION of the muscles
animals is used as and on the INTERNUNCIAL
fertilizer FIBERS of the spinal cord and
Mode of Transmission of C. the brain.
tetani Results into multiple muscle
o Break in skin integrity spasms
Person is at risk for infection Inhibits the spastic muscle
when there is any kind of from sending transmissions to
would (i.e. splinter or the brain, which would inhibit
salubsob, tooth decay, otitis progression of spasms. Due
media) to this, adjacent muscles will
also undergo spasm similar to
Important Concepts! a chain reaction or a domino
You need not be wounded by reaction.
a RUSTY OBJECT to acquire
tetanus In the wound, there would be an
inflammatory response:
In the newborn, tetanus Rubor - rednes
neonatorum is caused by poor Calor - heat
cord care. Tumor - swelling
Dolor - pain
When C. tetani enters the Functiolaesa – loss of function
body, it seldom migrates to
the bloodstream where
oxygen is present
Signs and Symptoms of Tetanus
C. tetani remains in the The patient manifests:
wound but the effects are o Restlessness
systemic o Fever
o Profuse Sweating
IMPORTANT CONCEPT!
Toxin is released to the blood IMPORTANT CONCEPTS!!!
and is responsible for the Masseter muscle is involved
manifesting signs and o It functions for
symptoms of the disease mastication, for
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opening and closing of o Resulting into
the mouth constipation
o Tetanus affects strong
muscles Abdominal muscles are
o Therefore, it affects the affected
closing of the mouth o Results into abdominal
muscle rigidity
o This is called o Abdomen is hard as a
LOCKJAW or board
PRISMUS o This sign serves as a
basis for recovery
Facial muscle is affected o If abdominal rigidity
o Gives rise to “risus decreases, it means
sardonicus” that the patient is on
o Known as the his way to recovery
“Sardonic Smile”
o Also known as “Ngiting Extremity muscles are
Aso” affected
o Patient is smiling but o Results into stiffness of
his eyebrows are extremities
raised. o There is difficulty in
flexing
Spinal muscle is affected o Robot gait is evident
o Resulting into the
Ophistotonus position Concept!
o This is the arching of Thus, almost all of the
the back muscles are rigid and stiff in
o In the vernacular, it is Tetanus!
called “LIAD”
Diagnostics for Tetanus:
Respiratory muscles are
affected 1. Clinical Observation
o Results to difficulty of Assess patient physically
breathing, dyspnea and Assess for the presence of
chest heaviness lockjaw
If this is positive, a logical
Genitourinary tract muscles question would be – “Do you
are affected have a wound”
o Results into urinary
retention 2. Obtain history of wound
o Intervention would Wound Culture
involve catheterization If there is a fresh wound,
microorganism is still present
Gastrointestinal muscles are there
affected
Concept:
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The shorter the incubation increase in the dose of
period, the poorer the the drug
prognosis
Shortest incubation period is 2 IMPORTANT CONCEPT!!!
– 3 days. When administering tetanus
An incubation period of one horse serum, always have
month has a better prognosis ready the following:
than an incubation period of 2 o EPINEPHRINE
– 3 days. o CORTICOSTEROID
These would be necessary to
Three (3) Objectives of Medical counteract any delayed
Management reaction, which may cause
hypersensitivity reactions
Neutralize the toxin leading to anaphylaxis and
This is the top priority eventually the death of the
The toxin is responsible for patient.
the signs and symptoms of
the disease and the systemic 2. Kill the Microorganism
infection Give Penicillin
Give anti-tetanus serum or o This is the drug of
tetanus anti-toxin choice to kill the
o It comes from a horse bacteria
serum In the fresh wound, do daily
o Do skin testing first cleansing with the use of
o If (+) for skin testing, hydrogen peroxide
DO NOT GIVE the Then apply antiseptic solution
drug. like Betadine or Povidone
Resort to human Then cover wound with THIN
serum – tetanus DRESSING to allow air to
immunoglobulin circulate through the wound.
It may also be good to expose
Concept: the wound but avoid contact
In the Philippine setting, the with flies.
horse serum is still given
despite a positive skin test. 3. Prevent and Control Spasm
This is done by giving Give muscle relaxant
fractional doses. o Given during the acute
Example: phase of tetanus
o Initial administration of o Done via the I.V. route
0.01 of drug and 0.99 Give Diazepam / Valium
PNSS o Use I.V. push or I.V.
o After 30 minutes, 0.05 drip
of the drug and 0.95 of
PNSS Concepts:
o After another 30
minutes, another
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I.V. drip regulation is titrated 3. Proprioceptive
based on the frequency of the There is participation of
spasm. patient and other persons
o The more frequent the Examples are touching,
spasm, the faster the turning, jarring the bed of the
rate of the titration patient
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Use padded tongue depressor When given:
for retaining patency of the o 1st Dose: 6 weeks
airway after birth; 0.5 ml
Respiratory Infection o 2nd Dose: 10 weeks
Turning to side is usually not after birth; 0.5 ml
done o 3rd Dose: 14 weeks
o This results to pooling after birth; 0.5 ml
of respiratory Number of Doses:
secretions in the lungs o Three (3)
o This leads to Interval between Doses:
pulmonary infection o Four (4) weeks
Profuse sweating and draft Administration Site:
exposure also leads to o Vastus lateralis muscle
pulmonary infection Route:
Therefore, always keep o Intramuscular
patient dry; especially at the
back. IMPORTANT CONCEPTS!!!
Expect fever to set in after
Physical Injury administration of DPT vaccine
For falls: o Give paracetamol
o Never leave the patient
o Apply warm compress
alone
for better drug
o If you do leave the
absorption
patient, keep the o Immediately follow up
padded side rails up
with cold compress to
o Keep call light within
avoid soreness
the reach of the patient If tenderness or swelling on
Fractures due to spasm: site of injection is present:
o Caused by restraining o Do cold compress
by relatives within twenty-four (24)
hours
Provide Patient with Comfort o Then do warm
Measures
compress
Oral care
Observe for signs of
o To prevent mouth sores
convulsions within seven (7)
o Cotton swab used on days after DPT immunization
inner and outer chick o This indicates that child
o Do not use toothbrush has reaction with the
pertussis component of
IMPORTANT CONCEPT!!! the drug
Attack of tetanus does not o Therefore, succeeding
give permanent immunity doses of DPT will NOT
BE GIVEN
Vaccine Given: o Give ONLY the DT
Diphtheria Pertussis Tetanus
components
Vaccine or DPT vaccine
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o If DPT is given again, 5th Dose given:
this predisposes the o 10-05-2007 (After one
child to neurologic (1) year from the LAST
disorders dose)
Observe if child cries
uncontrollably IMPORTANT CONCEPTS!!!
This is an Succeeding doses of Tetanus
indication of Toxoid are given based on
development of DATE OF LAST DOSE
neurologic If a person is high-risk, give
disorders. booster dose every five (5)
years
DPT Immunization for Pregnant If a person is low risk, give
Individuals booster dose every ten (10)
Dose: 0.5 ml years
Route: Intramuscular Effect of Tetanus Toxoid
Number of Doses given: administration on the Mother
o Two (2) doses with Slight soreness or heaviness
three (3) booster doses on site of injection
or;
o Two (2) doses with Wound Care
booster dose given Wash wound with soap and
every pregnancy running water
When given: Place antiseptic solution on
o 1st Dose: Anytime wound
during second trimester Use thin dressing
of pregnancy Band Aid Plastic Strips are
o 2nd Dose: With one allowable as they have air
(1) month interval ventilation holes
o Booster Dose: Given Do not use plaster
with successive Use only those types of
pregnancy/ies plasters with air ventilation
holes to introduce oxygen to
For High-Risk Individual the wound
1st Dose given:
o 03-05-2005 Key Concept!!!
Avoid Wounds
2nd Dose given:
o 04-05-2005
rd MENINGITIS
3 Dose given:
Inflammation of the meninges
o 10-05-2005 (six
(covering of the brain and
months after the LAST spinal cord)
dose)
th
4 Dose given: Concepts!
o 10-05-2006 (After one Meninges are composed of:
(1) year from the LAST o Dura mater
dose)
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o Arachnoid mater o Disseminated
o Pia mater Intravascular
Cerebrospinal Fluid or CSF is Coagulation occurs
found in the and leads to vascular
SUBARACHNOID SPACE collapse
o Vascular collapse leads
Causative Agents in Meningitis to death in ten percent
Viral (10%) of patients
o CMV – o This ten percent (10%)
Cytomegalovirus has the FULMINANT
Opportunistic TYPE or the
infection for Waterhouse-
AIDS Freiderichen Syndrome
Fungal (characterized by
o Cryptococcal vascular collapse)
Meningitis o Causative agent is
Source is Neisseria meningitides
excreta of fowls
and feathered Important Concept!
animals In children below four (4)
Another form of years old, Neisseria
opportunistic meningitidis is a normal flora
infection for in the nasopharynx.
AIDS If resistance goes down,
Bacterial these children become prone
o Tubercle Bacilli to infection
TB meningitis
Staphylococcal meningitis Mode of Transmission
o Secondary to skin Droplet transmission
infection In cryptococcal meningitis:
Haemophilus influenzae bacilli o Inhalation of spores
o Common cause of
meningitis in the United Portal of Entry
States Respiratory system via the
Meningococcemia nasopharynx
o Meningococcemial
meningitis Pathophysiology of Meningitis
o Spotted Fever Disease From the nasopharynx, the
o Most fatal microorganism goes to the
o The only type of bloodstream
Once in the bloodstream, the
meningitis where the
microorganism causes
VASCULAR SYSTEM
petechiae formation (pin point
is affected
red spots on the skin)
o Bleeding is triggered
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From the bloodstream,
microorganism goes to the Pathophysiology of
meninges and irritates them Meningococcemia
o There is inflammation Portal of entry of Neisseria
of the meninges and meningitidis is also the
accumulation of nasopharynx
substances in the The bacteria then goes to the
meninges bloodstream
This results into increased Presence of bacteria in the
Intracranial Pressure (ICP) bloodstream causes
o Increased ICP leads to: ecchymosis
Severe o These ecchymoses are
headache blotchy (pantal-pantal)
Projectile purpuric lesions
Vomiting o They are purplish in
Two (2) to three color
(3) feet away o Usually found on the
from patient wrist and the ankles
o Management involves From the bloodstream, they
turning patient to side go to the meninges and
Position kidney irritate them.
basin about two Same sequence of events
(2) to three (3) follow as mentioned above
feet away
Altered Vital Signs Signs and Symptoms of
o Increased Temperature Meningitis
o Decreased Pulse Rate Once the microorganism is at
o Decreased Respiratory the nasopharynx:
Rate o Fever
o Increase in Systolic o Headache
Blood Pressure and o Sore throat
Normal Diastolic o Cough
Pressure o Colds
This results in Other signs and symptoms
the widening of present as discussed in the
the Pulse pathophysiology
Pressure
Convulsions (seizures) Pathognomonic Sign of Meningitis
Diplopia Nuchal Rigidity
o Due to choking of optic Stiffening of the neck
discs o No flexing of the neck
o Double vision but not o No hyperextending of
crossed eyed the neck
o Determined by finger o No turning from side to
counting side
Altered level of consciousness Abnormal Reflexes
19
o Positive for Kernig’s Viral infection is present if:
Sign o CSF is clear
Place patient in No infection is present if:
supine position o CSF is clear
Flex both knees
toward the Send CSF for Laboratory
abdomen Examination
Then ask the Laboratory findings would
patient to extend show:
the legs o Increased protein
If pain is levels
present, the o Increased White Blood
patient is said to Cell levels
be positive (+) o Decreased Sugar
for Kernig’s Sign content
or difficulty of
extending the Concepts
leg If caused by bacteria, do
Positive for Brudzinski’s Sign Culture and Sensitivity test
o Place the patient in o This is done to know
supine position what bacteria caused
o Flex the neck the infection
o If there is no reaction, o This is also done to
the patient is said to be determine what drug
negative (-) for will be used to kill the
Brudzinski’s Sign. offending
o If there is microorganism
INVOLUNTARY
DRAWING UP of the If CSF is clear, it is subjected
LEGS / HIP upon to Counter Immuno-
flexion of the neck, the Electrophoresis (CIE)
patient is said to be This is done to determine if
positive (+) for causative agent or a protozoa
Brudzinski’s Sign
IMPORTANT CONCEPT!!!
Diagnostic Tests for Meningitis In patients with HIGHLY
INCREASED INTRACRANIAL
1. Lumbar Puncture PRESSURE due to CNS
Cerebrospinal Fluid (CSF) is infection, lumbar puncture or
the specimen used aspiration of the CSF is
o Assess for the color of CONTRAINDICATED
the CSF o This will bring about
Bacterial infection is present HERNIATION OF THE
if: BRAIN and would
o CSF is yellowish, eventually lead to
turbid, cloudy death
20
Therefore, it is important that the urine output must
the nurse performs Physical increase by thirty (30)
Assessment before doing a to fifty (50) ml.
lumbar tap. o If no changes in urine
output occurs, then
2. Blood Culture Mannitol is not effective
Done because microorganism o Refer this to the
can travel to the bloodstream physician
If there are convulsions due to
Medical Management of CNS infection
Meningitis o Give anti-convulsants
If bacterial Dilantin
o Give anti-bacterial Phenytoin
agent in the form of Routes of Administration of
antibiotics Dilantin
If viral o Per Intravenous
o Symptomatic Nursing Care for
If fungal I.V.
o Give Amphotericin B administration of
If with inflammation Dilantin
o Give corticosteroids in Sandwich
the form of Dilantin
DEXAMETHASONE with NSS
o Never give NSS –
PREDNISONE Dilantin –
Prednisone NSS
does not cross Rationale:
the Blood-Brain Dilantin
barrier would
Prednisone crystallize
causes sodium o Per Orem
retention Nursing Care for
Retains CSF P.O.
If with excess CSF administration of
o Give osmotic diuretic in Dilantin
the form of MANNITOL Do
o Check blood pressure frequent
before administration oral care
as it causes Do gum
hypotension massage
o Monitor the intake and o Rationale:
output to evaluate the Dilantin causes
effectiveness of gingival
Mannitol hyperplasia or
o Expect that after two overgrowth of
(2) to three (3) hours, the gums
21
4. Potential for fluid and
Important Concept! electrolyte imbalance due to
Dilantin is never given projectile vomiting
Intramuscularly Monitor intake and output
o This is irritating to the Provide fluids per orem
tissues
o This has an erratic Important Concept
effect An attack of meningitis does
not provide permanent
Nursing Care immunity
Symptomatic
Supportive Preventive Measures
22
Thus, for TB patients, they ENCEPHALITIS
have to spit out
nasopharygeal secretions Signs and Symptoms
Swallowing is allowable for With altered level of
other respiratory infections consciousness
With lethargy
2. Cover nose and mouth when o Difficult to awaken
sneezing and coughing o Patient is abnormally
sleepy
Important Concepts! With behavioral changes
When you transfer patient… Brain is immediately affected
o Make the patient wear relative to meningitis
a mask so as not to
infect people in the Diagnostic Tests
hallway, elevator, etc. 1. Lumbar Puncture
Wear mask when you enter Specimen is cerebrospinal
the patient’s room fluid (CSF)
Laboratory Results would
3. Vaccine indicate:
Hib vaccine for Haemophilus o Increased Proteins
influenza o Increased White Blood
Cells
BRAIN FEVER o Normal Sugar Content
Arbovirus
Arthropod-borne Virus 2. Electroencephalogram (EEG)
To assess extent of brain
Primary cause damage
St. Louise Patient recovers but because
Japan B he is epileptic, he develops
Australian X: Equine (E-W) irreversible brain damage
Medical Management
Mode of Transmission Symptomatic due to viral
Mosquito bites cause
o Aedes Sollicitans
o Culex tarsalis Concepts!
Ticks of horse No permanent immunity is
Migratory birds obtained from attack of
encephalitis, only temporary
Secondary cause immunity, due to causation by
Post racene encephalitis various viruses
23
CLEAN PROGRAM Important Concepts!
o C – Chemically Treated When Brunhilde infects you,
Mosquito Net Leon or Lansing will no longer
o L – Lavivorous fishes affect you!
o E – Environmental
Sanitation In the Philippines, the most
o A – Anti-mosquito Soap prominent type is Brunhilde!
(Basic Soap)
o N – Neem Trees or Mode of Transmission
Eucalyptus Tree (draws Droplet
away mosquitoes) o In early stage of
infection, virus if found
Concepts! at nasopharyngeal
To kill mosquitoes in canal, secretions
pour oil or gas in canal
o This depletes oxygen Fecal-Oral Route
present in the canal o In late stage of
o There is no need to transmission, virus is
light it up found at the mouth
24
Patient recovers respiratory
Disease process is aborted depression
But there will be instances
when disease process will not Once in the CNS, the
be aborted microorganism will also
cause:
Tonsils Peyer’s Patches o Stiffness of the
▼ ▼ hamstring
Cervical Mesenteric o Patient will be positive
Lymph Lymph for HOYNE’S Sign and
Nodes Nodes exhibit a HEAD DROP
▼▼▼ ▼▼▼ o To check for Hoyne’s
BLOODSTREAM Sign
▼▼▼ Lift shoulders of
Central Nervous System patient when
lying supine or
2nd Stage: Pre-paralytic Stage of extend head of
Poliomyelitis patient beyond
Central Nervous System is the edge of the
already involved but there will bed
be no paralysis If head of patient
drops, he is said
Signs and Symptoms: to be positive (+)
Once in the CNS, for Hoyne’s Sign
microorganism will cause:
o Sever muscle pain Once in the microorganism is
Do not keep on in the CNS, the patient would
turning or elicit a POKER SPINE
holding patient o Ophistotonus with head
Do not do retraction
massage o Sitting position cannot
No positioning be assumed
will relieve o Therefore, patient will
patient assume a TRIPOD
o Instead, what would POSITION
relieve the patient
would be: Central Nervous System
Application of ▼▼▼
warm packs Paralysis
Analgesics
o Never administer Concept!
Morphine From the CNS, the patient will
It is a narcotic experience paralysis.
analgesic that This leads to the third (3rd)
would cause stage of the disease
25
3rd Stage: Paralytic Stage Patient has cranial nerve
Presence of paralysis affectations and anterior horn
Characteristics of Paralysis: cell affectations
o Flaccid
Soft Important Concepts!!!
Flabby Not all patients will develop paralysis
Limp If patient is non-paralytic,
o He has GOOD
Important Concept! PROGNOSIS
Flaccid Paralysis is
PATHOGNOMONIC SIGN of Diagnostic Tests
Poliomyelitis
1. Lumbar Puncture
Three (3) Types of Paralysis Laboratory results would
reveal:
1. Bulbar Type o Increased White Blood
Cranial nerves are affected Cell levels
9Th cranial nerve o Increased Protein
(Glossopharyngeal Nerve) levels
and 10th cranial nerve (Vagus o Normal Sugar levels
Nerve) affectations give rise
to: 2. Muscle Testing
o Respiratory problems To determine what specific
o Vocal cord swelling / muscle is affected
paralysis
o Excessive salivation 3. Electromyelogram
o Aspiration To determine extent of muscle
o Regurgitation involvement
26
o This works on the 1st Dose – at six
principle of Negative (6) weeks old
Pressure Breathing 2nd Dose – at ten
o No tracheostomy tube (10) weeks old
needed (tracheostomy 3rd Dose – at
tube or endotracheal fourteen (14)
tube work on the weeks old
principle of Positive o Important Concepts!!!
Pressure Breathing) Do not feed
o Capsular in shape child for thirty
o With glass windows (30) minutes
o With metal plate after
o Works on electricity administration of
o During brownout or OPV
o Rationale:
power shortages,
operate the machine For better
manually absorption
o It has a steering wheel, o If child vomits,
which can be REPEAT!!!
manipulated manually o If child has diarrhea
o Patient stays in the Iron Give OPV
Lung Machine for But do not
months record it
Not all of the
Nursing Care for Poliomyelitis vaccine may be
Symptomatic and Supportive absorbed
Psychological Aspect of Care properly
o Use empathy When OPV 3 is
given four
weeks after,
Preventive Measures
record it as OPV
1. Immunization
2
Vaccine given:
o Oral Polio Vaccine
Integrated Management of
(OPV) or Sabin
Childhood Illnesses (IMCI)
o Dose:
o Tell mother also that
Two (2) to three
she should be very
(3) drops
careful in handling
o Route:
stool of child because
Oral this vaccine eliminates
o Number of Doses: virus to the stool
Three (3) o If significant others at
o Interval: home are
Four (4) weeks immunocompromised
o When given: o Do not administer OPV
o Due to feces of child
27
o Rather give, IPV or o Fox
Inactivated Polio o Wolves
Vaccine / SALK o Boar
o Dose: o Monkeys
0.5 cc o Bats
o Route: o Cats
Intramuscular o Dogs
o Number of Doses:
Three (3) Causative Agent:
o Interval: Rhabdovirus
Four (4) weeks o A neurotropic virus
o When given: o Has special affinity to
1st Dose – at six neurons and the
(6) weeks old Central Nervous
2nd Dose – at ten System
(10) weeks old
3rd Dose – at R H A B D O V I R U S
fourteen (14) ▼▼▼ ▼▼▼
weeks old Peripheral Efferent
o Rationale: Nerves Nerves
Because stool of ▼▼▼ ▼▼▼
child may CNS Salivary
contain the virus Pathologic Gland
if OPV is given Lesions of Rabid
(negri bodies) Animal
28
o Corneal transplantation years (this is the
o Kissing animal longest
o Dog licking wounds incubation
period recorded
Manifestation: in the
In Animals Philippines)
o Incubation Period
Three (3) to Stage 1 – Invasive Stage
eight (8) weeks Numbness on the site of the
bite
Stages of Manifestations in Itchiness on the site of the
Animals bite
Flu-like symptoms
Stage 1 – Dumb Stage o Fever
Animal will have complete o Headache
change in disposition o Sore throat
May show any of the following Marked Insomnia
behaviors: Restless
o Withdrawn Irritable
o Stays in one corner Apprehensive
o Depressed Slight photosensitivity
o May be overly Vague symptoms
affectionate
Can lick wounds Important Concept!
o May be walking to and When a family member at
home is bitten by a rabid
from
animal, vaccinate all people at
o Hyperactive
home because patient has
o Manic
virus at saliva
It is better if the animal is
withdrawn as it is easy to note Stage 2 – Excitement Stage
Acrophobia
Stage 2 – Furious Stage o Fear of Air
Easily agitated
Hydrophobia
Easily bites
o Fear of Water
With vicious look
Important Concept!
With drooling of the saliva
Air and Water both cause
Expect the animal to die
PHARYNGOLARYNGEAL
Dying and biting happens on
SPASM
this stage
This is characterized by:
Animal can die without biting
o A drowning sensation
Manifestation: o Strangulation to death
In Humans syndrome
o Incubation Period o Like breathing in thick
Ten (10) days to smoke
twenty one (21) Other signs and symptoms
29
o Photosensitivity
o Maniacal behavior Brain Biopsy of the Animal
o Resembles attitude of Identifies presence of negri
a rabid animal bodies
o Easily agitated 10% of animals have rabies
o Runs after people but are negative for negri
o Violent bodies
o Because virus may
o Club walls
travel through efferent
o Jumps out of window
nerves and may not
have reached the CNS
Important Concepts!
before death
Before, THORAZINE and
Therefore, do the next test…
BENADRYL were given for
maniacal behavior but had
Direct Fluorescent Antibody Test
proven to be ineffective
(DFA Test)
Now, HALOPERIDOL and
Confirmatory test for rabies
BENADRYL are administered
and are very effective against
Observation of the Animal
maniacal behavior
Done for ten (10) days
Important Concept!
Stage 3 – Paralytic Sage
o Submit yourself for
Patient’s spasms will stop
treatment if, within ten
He can be fed, etc.,
(10) days:
Paralysis sets in from toes
Animal dies
going upwards
Animal shows
If respiratory system is
behavioral
affected, the patient will die
changes
Manifestation of signs and
Consider the following:
symptoms sets within 24
o Site of Bite
hours and death follows
If above waist
Important Concept!!! Submit
Rabies is a preventable but yourself
not a curable disease for
Maximum time before death treatment
occurs is seventy-two (72) as soon
hours. as
possible
Diagnostic Tests Done Before This is
Patient Manifests Signs and due to the
Symptoms proximity
of the bite
Important Concept! to the
There is no diagnostic brain
examination done to humans, o Velocity of Virus
ONLY TO ANIMALS
30
Three o Stock dose is 0.5 cc /
millimeters per vial
hour (3mm/hr)
o Extent of Bite Purified Duck Embryo Virus
Submit yourself o PDEV
for treatment at o Lyssavac
once if: o Stock dose is 1.0 cc /
You have vial
multiple
bites Purified Chick Embryo Cell
You have o PCEC
a deep o Also one of the more
bite common types
o Reason for the Bite o Rabipur
If bite is o Stock dose is 1.0 cc /
provoked vial
Example:
You Important Concepts!!!
stepped If given intramuscularly (I.M.)
on the o Do skin testing first
dog’s tail If given intradermally (I.D.)
Do not o No skin testing is done
worry Site
If unprovoked o Deltoid
Example: o Vastus lateralis
There is
Important Concepts!!!
no reason If active form of vaccine
Then, If via I.M.
WORRY, Schedule is:
because Dose Day Example Dosage Remarks
IT IS A 1st 00 03/05/ 2 vials 1 cc on
RABID 2005 each site;
DOG!!! One on
the left
and one
on the
Medical Management right
Post-Exposure Prophylaxis 2nd 07 3/12/ 1 vial One site
Vaccines 2005 only
3rd 21 3/26/ 1 vial One site
2005 only
Active Form of Vaccine
Important Concepts!!!
Made up of microorganisms
Counting is ALWAYS BASED
Purified Vero Cell Vaccine
on the FIRST DOSE!!!
o PVCV
You can afford not to continue
o One of the more
vaccine if dog does not die
common types after ten (10) days
o Verorab
31
However, continuance is 4th 28 04/01/ 0.1 cc if Given on
encouraged because doing so to 2005 Verorab one site
30 to or only
would give three (3) years of 04/03/ 0.2 cc if
immunity 2005 Lyssavac
If you abort vaccination, you Or
will not get three (3) years of Rabipur
immunity 5th 90 06/03/ 0.1 cc if Given on
2005 Verorab one site
When you get bitten again, or only
you start all over again 0.2 cc if
In case the dog: Lyssavac
o Died Or
o Disappeared Rabipur
o Was killed within (3) Important Concepts!!!
Verorab
days
o Once reconstituted is
Avail of complete doses plus a
BOOSTER DOSE only potent for eight (8)
o Booster Dose hours
Antibodies are produced in
Given at DAY 91
about seven (7) days
In the tabulated
Therefore, also give passive
example
form of vaccine.
Schedule
would be
at
Passive Forms
6/05/2005
Temporary antibodies
Dosage is
one vial Animal Serum
If via I.D. Equine Rabies
Schedule is: Immunoglobulin (ERIG)
Dose Day Example Dosage Remarks
1st 00 03/05/ 0.1 cc if Given on o Anti-rabies serum
2005 Verorab each site: o HyperRab
or Right and o FaviRab
0.2 cc if Left
Lyssavac
Or Important Concepts!
Rabipur Do skin test first
2nd 03 3/08/ 0.1 cc if Given on o If negative for skin test,
2005 Verorab each site: give drug
or Right and
0.2 cc if Left
Dosage is based
Lyssavac on body weight
Or and is provided
Rabipur in direct
3rd 07 3/12/ 0.1 cc if Given on proportion
2005 Verorab each site:
0.2 cc / kg body
or Right and
0.2 cc if Left weight is the
Lyssavac standard
Or Example:
Rabipur
32
A 50 kg side of the
person buttocks
would o Other half is...
receive Infiltrated
10 ml of around site of
ERIG bite using four
Cost is distinct points or
approxim Given inside the
ately wound of the
Php1,800 patient
/ 5.0 cc o This is prophylactic and
o If positive for skin test, is not considered as a
give HRIG or Human treatment
Rabies Immunolobulin
Imogam Nursing Care
Rabuman Place patient in a dim and
0.133 cc / kg quiet environment
body weight is Keep patient away from sub-
the standard utility room
dose Restrain the patient before he
Example: exhibits maniacal behavior
A 50 kg Wear all Personal Protective
person Equipment when you enter
would the room because patient
receive continues to spit
6.65 cc of
HRIG Preventive Measures
Cost is Be a responsible pet owner
approximately o Have pets immunized
Php4,500 / 2.0 Wash wound with soap, water
cc and antiseptic
o This is given as a Then observe the dog
single dose within
seven (7) days from Important Concept!!!
the date of the bite Virus rabies is destroyed by
o After seven days, 60°C heat for thirty-five (35)
patient already has seconds
antibodies Therefore, you will not acquire
o Computed Dosage is rabies from eating dog meat
divided in two
Half is given
Intramuscular COMMUNICABLE DISEASES OF
On the THE CIRCULATORY SYSTEM
ventrogluteal
muscle or at the
DENGUE HEMORRHAGIC FEVER
33
Life span of these types of
mosquitoes is four (4) months
Important Concept!
Dengue Fever is different from
Dengue Hemorrhagic Fever! Mechanical Transmitter
Dengue fever is an affectation After this mosquito bites an
of the circulatory system infected person, the very next
without bleeding person it bites is the only
o It is a mild form of person who gets the virus.
hemorrhagic fever One is to one
Immediate transfer of virus
Causative Agent:
Arbovirus Aedes aegypti
Carried from one person to More common in the
another by an Arthropod Philippines
Day-biting
Low-flying
Types of Dengue Viruses Low-extremity biting
Type 1 – Onyong-nyong virus Breeds on clear, stagnant
Type 2 – Chikungunya water usually in urban area
Type 3 – West Nile o Old tires
Type 4 – Flavivirus o Flower vases
o Brought epidemics in o Plant cans
several areas in the In the Philippines, any area is
Philippines a dengue risk area
Other information:
o When it lands on a
Mode of Transmission surface, body of
Mosquito Bite mosquito is on a
Biological Transmitters PARALLEL POSITION
o Aedes aegypti and two (2) legs are
o Aedes albopectus raised
Mechanical Transmitter o It has white stripes on
o Culex fatigans legs
o It has a gray-
millennium color
Biological Transmitter
After this mosquito has bitten Four Classifications of Dengue
an infected person, after eight Hemorrhagic Fever
(8) to ten (10) days, it can
transfer virus to other people DHF Grade 1
Virus becomes a part of the Increased grade fever (lasts 3
system of the mosquito as – 5 days)
long as it is alive o Even if antipyretics are
given, fever will persist
34
o Fever will come down If patient recovers, he only
but the patient is still has Dengue Fever (and not
febrile Dengue Hemorrhagic Fever)
o Important Concept! Dengue Fever is also called:
Therefore, give o Dandy Fever
antipyretic round o Breakbone Fever
the clock
Pain is present DHF Grade 2
o Headache If there is persistence of signs
o Periorbital pain and symptoms of DHF Grade
o Pain behind the eyes 1
o Joint and bone pain If there is bleeding from:
o Abdominal Pain o Nose – epistaxis
Nausea and o Gums – gum bleeding
Vomiting o Vomiting of blood –
Presence of Pathological Hematamesis (coffee
Vascular Changes ground appearance
o Petechiae from the stomach)
o Herman’s Sign Upper Gastro-Intestinal Tract
Generalized Bleeding
redness o Melena
Flushing of the skin Passing of black
tarry stool
Acted upon by
INFECTED MOSQUITO digestive
▼▼▼ enzymes
BLOODSTREAM (multiplies) Lower Gastro-Intestinal Tract
▼▼▼ Bleeding
Multiple lesions in the o Hematochezia
bloodstream Passing of fresh
▼▼▼▼ ▼▼▼▼ blood in the
Increased Increased stool
Capillary Capillary Then, these signs and
Fragility Permeability symptoms indicate the START
(causes easy (allows shifting OF HEMORRHAGIC FEVER
bleeding; of fluid from
difficult to stop one DHF Grade 3
due to compartment Persistence of signs and
thrombocytopenia; to symptoms of DHF Grade 2
poor clotting another leads With signs of circulatory
to ascites; collapse or failure
hemo- With cold clammy skin
concentration Nursing Alert!
o Check for capillary refill
Important Concept! o How?
35
Apply pressure Three (3) criteria that must be
on nailbeds present before you perform
Normal capillary the tourniquet test:
refill time is o Person must be at
about one (1) to least six (6) months old
two (2) seconds o Fever should be more
If capillary refill than three (3) days
time is about o No other signs of DHF
three (3) are present
seconds or Patient only
more, blood flow feels fever
is sluggish due If there are other
to circulatory manifestations (i.e.
failure stomachache), do not do
Check Vital Signs tourniquet test
o Indicators of How is it done?
Circulatory Failure: o Get the blood pressure
Hypotension or of the patient
decreased blood o Add systolic and
pressure diastolic pressures
Rapid but weak o Divide the sum by two
pulse o Apply that pressure on
Rapid
the cuff. . .
respiration
For five (5)
minutes if the
DHF Grade 4
patient is
With signs and symptoms of
pediatric
DHF Grade 3
For ten (10)
With shock
minutes if the
Hypovolemic shock due to
patient is an
excessive blood loss due to
adult
uncontrolled bleeding
o Deflate the Blood
Pressure Cuff
Diagnostic Tests for Dengue
o Check for the presence
Hemorrhagic Fever
of petechial formation
1. Tourniquet or Rumpel Leede’s o If greater than or equal
Test to petechial formations
Test for capillary fragility per square inch, then
Concept! patient is positive (+) to
o This is only a Tourniquet Test
presumptive test for o Therefore, patient is
DHF (not a probably suffering from
confirmatory test) Dengue Hemorrhagic
o Not all patients are Fever
subjected to this test To confirm the diagnosis, do
the next test. . .
36
associated
2. Blood Examination with viral
Platelet Count infection
o Normal value is If there is bleeding
150,000 to 400,000 o Give coagulants
platelets per cubic Vitamin K
millimeter Aquamephyton
o Values lower than the Konakion
normal indicate that Vitamin C
patient is positive (+) To increase capillary
for Dengue resistance
Hemorrhagic Fever Provide blood transfusion
Hematocrit Determination
o Measures degree of Nursing Management
hemoconcentration Prioritize bleeding prevention
o Normal value is 37% to and control
54% For gum bleeding
o Values higher than the o Use cotton swab
normal indicate that o This is softer than any
patient is positive (+) toothbrush
for Dengue Provide ice chips
Hemorrhagic Fever Advise patient to gargle
o It will not cause injury
Medical Management o Use mouthwash
Symptomatic Use soft-bristled toothbrush
No specific treatment o Consider this as the
last measure to be
Important Concepts! taken compared with
If patient is febrile the three others above
o Administer antipyretic Keep patient on NPO if
o But never use aspirin patient vomits blood
Potentiates Apply ice pack over epigastric
clumping of region of patient
platelets Doctor may order NGT
Results to insertion
bleeding For gastric lavage, use ice
o ASA is not given to cold NSS or coagulant
children below twelve Provide adequate nutrition
(12) years old and Avoid dark colored foods
when cause of disease
is unknown.
Side effect is Important Concept!
Reye’s Attack of Dengue
Syndrome Hemorrhagic Fever does not
A neurologic give permanent immunity
disorder
37
o It breeds in CLEAR,
Prevention: SLOW FLOWING
Practice CLEAN PROGRAM WATER
of the DOH o It is common in
Rural Areas
Mountainous
MALARIA Areas
Also called Ague Forested Areas
King of tropical diseases Palawan
Manifested by indefinite Dumaguete
periods of chills and fever Surigao
o It lands on the surface
on a forty-five (45)
Important Concepts! degree angle or in a
Microorganism is a slanting position
PROTOZOA
Plasmodium has four species
o Plasmodium malariae
o Plasmodium ovale
o Plasmodium vivax
One of the most Pathophysiology of Malaria
common in the
Philippines P LAS M O D I U M
o Plasmodium falciparum ▼▼▼
Another of the BLOODSTREAM
most common in ▼▼▼▼ ▼▼▼▼
the Philippines Inside RBC (for Those that don’t
o The most fatal due to reproduction) penetrate RBC
its tendency to multiply go to the LIVER.
rapidly They do nothing
Plasmodium is acquired and may remain
through a mosquito bite – dormant for
Anopheles mosquito 3 – 5 years.
Blood is needed by the female They wait for the
Anopheles mosquito for the liver to release
fertilization of its eggs the RBC for
them to
penetrate other
Important Concepts! RBC
Anopheles mosquito is ▼▼▼
o A NIGHT biting Inside RBC
mosquito
It bites from Important Concepts!!!
sunset to Once inside the Red Blood
sunrise or from Cells (RBC), the
dusk to dawn
38
microorganism multiplies and o Headache
destroys the RBC. o Abdominal Pain
This leads to ANEMIA! o Vomiting
Rupturing of membranes of Nursing Responsibilities
Plasmodium coincides with o Lower the body
the presence of CHILLS in the temperature
patient o Provide tepid sponge
Presence of more or new bath
microorganisms in the o Provide cold compress
bloodstream causes FEVER!
o Increase fluid intake
o Provide light, loose
Important Concepts!
If you have malaria and your clothing
last attack is more than five o Provide antipyretic as
(5) years ago, then you can ordered
be a blood donor
If your last attack is less than Stage 3 – Wet Stage
five (5) years ago, you Patient exhibits:
CANNOT BE A BLOOD o Profuse sweating
DONOR o Feeling of weakness
Malaria can also be obtained
by BLOOD TRANSFUSION Nursing Responsibilities
o Make patient
Manifestations of Malaria comfortable
o Keep patient dry and
Stage 1 – Cold Stage warm
Lasts for ten (10) to fifteen o Provide fluids to
(15) minutes prevent dehydration
Chilling sensation is present o Make patient rest
Shaking, chattering of the lips comfortably in bed
is present
Nursing Responsibilities Important Concepts!!!
o Provide warmth In other types of sicknesses
o Blankets or disorders, chills occur
o Warm drinks before fever
o Not warm compress This is due to body’s response
o Hot water bag on soles to heat loss
of the feet In ordinary infections, higher
o Expose to heat lamp or temperatures are seen during
droplight CHILLS because patient is
trying to retain heat
Stage 2 – Hot Stage In malaria, increased
Last for four (4) to six (6) temperature occurs on
hours FEVER or HOT STAGE
The patient has: There is no fever during the
o Fever cold stage
39
Chills occur due to the release During the Hot Stage, the
of Plasmodium microorganism is in the
bloodstream
Key Concept! During the Cold Stage, the
If causative agent is P. microorganism is inside the
falciparum, its rapid red blood cells
multiplication and RBC
destruction would lead to… Quantitative Buffy Coat (QBC)
o Anemia This is seldom done
o Liver then This test is expensive
compensates and Specimen used is blood
results to A rapid test for malaria
HEPATOMEGALY You do not have to wait for
o Splenomegaly fever to set in to undergo this
o Mild jaundice test
sometimes occurs You can extract blood earlier
o Cerebral Hypoxia
Restlessness Medical Management of Malaria
Confusion Anti-malarial Agents
Delirium Drug of Choice
Convulsions o Chloroquine
Loss of Other Drugs used:
consciousness o Primaquine
Coma o Atabrine
o Black Water Fever o Pancidar
Passing out o Quinine
black urine or A reserve drug
dark red urine for severe type
due to rapid of malaria
RBC destruction
This may lead to Important Concepts!
death Anti-malarial agents are
cautiously used in pregnant
Diagnostic Tests for Malaria women
They are considered as
Blood Smear or Malarial Smear ABOTIFACIENT AGENTS
Best time to collect o They can cause
o At the HOT STAGE ABORTION
o At the peak of fever However, this is NOT
(this is when the CONTRAINDICATED
microorganism is in the because if mother (infected
blood stream) with malaria) is not treated,
the child may be born with
Concepts! NEONATAL MALARIA
Child with Neonatal Malaria
exhibits the following:
40
o Decreased levels of Three (3) C’s
RBC o Coryza
o Immature liver o Cough
o Severe anemia o Conjunctivitis
Child may die Kuplick Spots
o Fine red spots with
Key Concepts! bluish white spot at the
Malaria may be acquired center
through: o Found at the inner
o Blood Transfusion cheeks
o Vertical Transfusion o This is the
RBC passes PATHOGNOMONIC
through the SIGN of Measles
placenta (not the
microorganism) Eruptive Stage
Rashes are now present
Important Concept! Maculopapular Rashes
An attack of Malaria does not o Flat to elevated
provide permanent immunity o Reddish in color
A repeat bite from a malaria o With blotchy
mosquito is not needed appearance
because the microorganism o In the vernacular,
may be dormant in the liver pantal-pantal
Prevention o Face of the patient
Practice the CLEAN
looks bloated
PROGRAM of the DOH
o Cephalocaudal
distribution
COMMUNICABLE DISEASES OF
Appears first on
THE INTEGUMENTARY SYSTEM
the hairline
Head to toe
Viral Communicable Diseases
distribution
Measles
o Appears on the 3RD
German Measles
Chicken Pox DAY of illness
Herpes Zoster o Within two (2) to three
(3) days, the entire
MEASLES body will be covered
with rashes
Causative Agent
Morbilli 3. Post-eruptive Stage
o Paramyxovirus Time when rashes start to
Rubeola Virus disappear
Fine, branny desquamation
Manifestations of Measles appears
Then the desquamation peels
1. Pre-eruptive Stage off
41
Peeling off proceeds in a Keep patient’s back dry and
cephalocaudal manner warm
It is only the rashes that will o Rationale
be peeling off, NOT THE Exposure to
SKIN of the patient draft gives rise
Concept! to cough and
o Use of Colantro cold
o Has a burning effect It gives rise to a
o Causes skin to likewise good medium
peel off for growth of
o Use of colantro is now microorganisms
discouraged Leads to
pulmonary
Diagnostic Tests for Measles complications
like pneumonia,
Concept! which could lead
There is no specific diagnostic to death
test for measles Provide hygienic measures
o Eye care
1.Clinical Observation Measles
patients have
Medical Management for Measles much “MUTA”
Symptomatic Management To prevent eye
Recovery dependent on complications
Nursing Care o Ear care
To prevent otitis
Nursing Care media
Maintain and increase body o Mouth care
resistance of the patient o Nasal care
Provide the following: o Skin care
Adequate rest Taking a bath or
Adequate nutrition taking a sponge
o No diet restrictions bath is not
o Provided that patient is contraindicated
not a hypersentitive However, do not
individual (i.e. prone to expose the
allergies) patient to draft
o Seafood or poultry
products are Other Nursing Care
contraindicated if the Symptomatic nursing care
patient is allergic to Patient is photophobic
these foods o Provide dim and quiet
o Increase oral fluid environment
intake
o Especially those rich in Important Concept!
Vitamin C
42
Attack of measles gives o Age of fifteen (15)
permanent immunity to the months
disease Dosage:
o 0.5 cc
Key Concept! Route:
When is the patient o Subcutaneous
communicable? Site:
Patient is communicable o Deltoid muscle
before rashes appear or Ask mother if the child has
during the pre-eruptive stage. allergies to egg and neomycin
o MMR is made up of
Preventive Measures duck embryo and
1. Immunization neomycin
Anti-measles vaccine (AMV) o If patient is allergic to
When given:
egg
o Age of nine (9) months
Give vaccine
Dosage: But observe for
o 0.5 cc signs and
Route: symptoms of
o Subcutaneous allergies
Site: o If patient is allergic to
o Deltoid muscle neomycin
Important Instructions to be Do NOT give
given to the mother of the MMR vaccine
patient! It may cause
o Child may experience anaphylaxis
fever
o Give paracetamol to Important Concept!
lower the body DOH Program on Measles
temperature o Ligtas Tigdas
o After three (3) to four Immunization Program
(4) days, child will have in 2004
a rash formation. This
is a NORMAL Mode of Transmission
REACTION to the Airborne
vaccine
o In fact, it is a good Prevention
reaction, indicating that Proper disposal of
the patient’s body has nasopharyngeal secretions
produced anti-bodies to Cover the mouth when
measles coughing or sneezing
Key Concepts!!!
Important Concepts! Measles is not fatal by itself
In the private setting, MMR Common complications
vaccine is given… o Bronchopneumonia
When: o Encephalitis
43
o Rashes are smaller
GERMAN MEASLES compared with those of
Also called: measles
o Rubella o Also has
o Three (3) day disease cephalocaudal
o Poteln distribution
o Appears first at the
Causative Agent head
Pseudoparamyxovirus Important Concept!
o Rubella Virus o Once the rashes
Togavirus appear, within twenty-
four (24) hours, the
Mode of Transmission entire body is filled with
Droplet (not airborne) rashes
o However, head-to-toe
Manifestations of German Measles distribution is not as
distinct as in measles
1. Pre-eruptive Stage Key Concepts!
Fever may be present or o Patient is positive for
absent enlargement of lymph
If patient has fever, it lasts nodes
only for one (1) to two (2) Suboccipital
days lymph nodes
Patient has mild cough and Posterior
mild cold auricular lymph
NO CONJUNCTIVITIS nodes
o Therefore, he only has Posterior
two (2) C’s. cervical lymph
Important Concept! nodes
o Enanthem of German o This is a differentiating
Measles are called factor between German
FORSCHEIMER Measles (positive for
SPOTS enlargement of lymph
Fine red spots nodes) and Measles
Also called (negative for
petechial spots enlargement of lymph
Appears on the nodes).
soft palate
3rd Stage – Post-Eruptive Stage
nd
2 Stage – Eruptive Stage Rashes now start to
With maculopapular rashes disappear
o Not reddish but pinkish But they disappear at the third
o Not blotchy but discreet (3rd) day of illness
o Appearance is fine Important Concept!
o Slightly unnoticeable o In measles, rashes just
start to manifest
44
themselves by the third After three (3) days, the virus
(3rd) day of the illness has already passes through
o Enlarged lymph nodes the placenta
will gradually subside o Therefore, once
pregnant, women
Diagnostic Tests, Medical should be already
Management, Nursing given gamma globulin
Management and Preventive German Measles is more fatal
Measures for German Measles are to pregnant women relative to
THE SAME AS THAT FOR Measles
MEASLES All people have been exposed
to measles, therefore, anti-
Important Concepts! bodies to measles have
An attack of German Measles already been developed.
gives permanent immunity Not all have been exposed to
When is German Measles German Measles, therefore,
communicable? not all have developed anti-
o During the entire bodies to German Measles
course of the disease. MMR vaccine
o Until enlarged lymph o Measles, Mumps,
nodes return to normal Rubella vaccine
German Measles is NOT o If you are an
FATAL adolescent, you can
It can become fatal if patient receive this but do not
is on her first trimester of be pregnant within the
pregnancy due to chances of next three (3) months
giving birth to a child with because you may give
congenital anomalies: birth to a child with
o Microcephaly congenital anomalies
o Congenital Defect
(Tetralogy of Fallot, CHICKEN POX
etc.) Also called Varicella
o Cataract leading to
blindness Causative Agent
o Deafness and mutism Varicella Zoster Virus
Mere exposure of pregnant o Can be found both on:
woman to German Measles Nasopharyngeal
MUST BE AVOIDED Secretions
o If exposed during the Secretions of
first trimester of rashes
pregnancy, pregnant o But only causes
mother must infection if. . .
immediately receive It enters the
immunoglobulin or nasopharynx
gamma globulin within
seventy-two (72) hours.
45
o Does NOT cause
infection by skin to skin Additional Concepts!!!
contact These rashes are itchy
Therefore, it is a MUST that
Mode of Transmission the patient takes a bath DAILY
Airborne If the patient does not take a
bath. . .
Three (3) Stages of Manifestation o Patient will perspire
o Patient will accumulate
Stage 1 – Pre-Eruptive Stage dirt
Presence or absence of low- o Dirt + Wetness + Itchy
grade fever rashes will lead to
Headache greater itching and
Body malaise would eventually result
Muscle pain into SCRATCHING
Lasts for twenty-four (24) to Scratching may be avoided
forty-eight (48) hours while the patient is awake
However, scratching during
Stage 2 – Eruptive Stage sleep is common among
Presence of rashes Chicken Pox patients
o Vesiculopustular
rashes Key Concept!
Development of Do not scratch rashes
Vesiculopustular Rashes: Scratching results to infection
o Initially, these rashes or pox marks!!!
are macules – FLAT
RASHES SCRATCHING WHILE ASLEEP
o They will become ▼▼▼
elevated or become RUPTURES THE VESICLES
PAPULES ▼▼▼ ▼▼▼
o Then, another set of Leads to skin Permanent
macules appear Infection Scar
o The original rashes ▼▼▼ (Pox mark)
(now papules) will Becomes a
become vesicles Boil,
o Pus then develops or a Furuncle
Important Concept! (big Boil),
o It is only during the or a Carbuncle
eruptive fever stage (several boils
that you can see all the attached to one
following: another)
Macules ▼▼▼
Papules Results to cellulitis
Vesicle or gangrene
Vesiculopustular
Rashes Important Concepts:
46
The distribution of the rashes
are: 3rd Stage – Post-Eruptive Stage
o Generalized Rashes now start to crust
o Found all over the body They start to dry
Found first on the trunk They start to peel off
Found on the covered parts of If rashes start to dry, let them
the body peel off by themselves
Then found on the scalp If allowed to dry and peel off,
Abundantly found on the there will be no infection
covered parts of the body and However, it leaves a pox mark
then on the exposed parts of
the body Diagnostic Test for Chicken Pox
Clinical Observation
Key Concept!
Period of Communicability Medical Management of Chicken
o Until the LAST RASH Pox
has crusted!!! Symptomatic management as
o Easily and highly- causative agent is a virus
contagious upon the
appearance of rashes Additional Concepts!
Zovirax or Acyclovir
Important Concepts! o Not a treatment for
During the summer season, if chicken pox
you have not had chicken pox o Virus is not always
and if you are responsive to this drug
immunocompromised, DO o Some viruses are
NOT GO OUT resistant (drug has no
Duration of the Disease effect) while some are
o Two (2) weeks sensitive to it and
patient will heal within
Important Characteristic of three (3) days
Chicken Pox Rashes o Dosage is four (4) to
Rashes have UNIFOCULAR five (5) tablets per day
appearance for one week
They have one focus Zovirax Cream
Rashes appear one at a time o Protects skin from
and they NEVER FUSE infection but does not
TOGETHER protect against pox
There is always a gap marks
between one rash to another Zovirax may be effective but it
rash does not allow the patient to
o If rashes get into produce antibodies.
contact with each Therefore, let the normal
other, it is no longer course of Chicken Pox occur
Chicken Pox.
o It is HERPES ZOSTER Nursing Care for Chicken Pox
47
Same as in measles the nerve and become
But more focus should be dormant
given on SKIN CARE Therefore, next exposure to it
o Rationale: will not give you Chicken Pox
To prevent skin New Varicella Zoster Virus will
infection go to the nerve and activate
Complication is dormant virus to give you
encephalitis Herpes Zoster
Herpes Zoster is the dormant
Important Concepts! or inactive type of Chicken
Attack of Chicken Pox gives Pox
permanent immunity You CANNOT have Herpes
Period of Communicability Zoster until you have obtained
o Until last rash has Chicken Pox
crusted Adults usually affected by
Herpes Zoster because what
Preventive Measures is affected is the ganglion of
1. Immunization posterior nerve root
Varivax
o Varicella Vaccine HERPES ZOSTER
Dosage Also called
o 0.5 cc o Shingles
Route o Zone
o Subcutaneous o Acute Posterior
For children below thirteen Ganglionitis
(13) years old
o Single dose is given Causative Agent
o Site of administration is Varicella Zoster Virus
the deltoid muscle
For those thirteen (13) years Mode of Transmission
old and above Droplet
o Two doses are given
o With one (1) month Manifestations of Herpes Zoster
Same as those of Chicken
interval
Pox
Rashes are also
2.Proper disposal of nasopharyngeal
vesiculopustular
secretions
However, there are
differences in the
3.Cover nose and mouth when
characteristics of rashes
sneezing or when coughing
Herpes Zoster rashes are:
o Not itchy
Important Concepts!
Not all of the Chicken Pox o More of painful
virus would leave your body. because nerves are
Some are left behind, travel to affected
48
o Even if patient has and
recovered and rashes remove
are long gone, pain the fishy
may be persistent up to odor
two (2) months. This is
NORMAL Important Concept!
o Rashes do not have An attack of Herpes Zoster
generalized distribution does not give permanent
o Has a unilateral immunity
distribution because it Most common complications
follows the nerve of Herpes Zoster
pathway o Skin infection
o Always vertical or o Encephalitis
longitudinal (on one
side) Preventive Measures
o Rashes do not have Same as that of Chicken Pox
unifocular appearance
but APPEARS IN Important Concepts!!!
CLUSTERS Children are mostly affected
in:
Diagnostic Test and Medical o German Measles
Management for Herpes Zoster o Measles
Same as in Chicken Pox o Chicken Pox
Additional Medical Management Adults are mostly affected in:
Application of Potassium o Herpes Zoster
Permanganate (KMnO4)
compress over the rashes of COMMUNICABLE DISEASES OF
the patient THE RESPIRATORY SYSTEM
Rationale:
o To obtain three-fold Bacterial
effect Diphtheria
Astringent effect Pertussis
To dry the Tuberculosis
rashes Pneumonia
Bactericidal
effect Viral
To Colds
decrease Influenza
chances
of skin Causative Agent
infection Corynebacterium diphtheriae
Oxidizing effect (Klebs-Loeffler Bacillus)
To This bacteria does not only
deodorize affect the respiratory tract
the o If it affects the mucous
rashes membrane, this is
49
called CUTANEOUS bloody, smells like a
DIPHTHERIA rat)
Types of Cutaneous Due to rubbing of nose, this
Diphtheria results to upper lip and nasal
o Conjunctival Diphtheria excoriation
Conjuctiva is Pathognomonic Sign
affected o Presence of
o Vaginal Diphtheria pseudomembrane
Vaginal mucosa o However, not
is affected appreciable in the
o Diphtheria of the NASAL TYPE
Prepuce o This is found within the
Affectation of the nasal septum
uncircumcised o Speculum is needed
prepuce of the o But is usually covered
male by irritating nasal
o Wound Diphtheria discharge
Affects wounds
Especially of 2. Pharyngeal Type or Faucial
burn patients Type
Affects the pharynx and the
Important Concepts! tonsils
Respiratory Diphtheria Patient complains of:
o Is the more common o Sore Throat
type of diphtheria o Dysphagia
Wound Diphtheria Presence of
o Is the rare type of pseudomembrane, which is
diphtheria visible upon opening of the
mouth
Mode of Transmission Pseudomembrane is present
Droplet on the following:
o Soft palate,
Manifestations of Diphtheria o Uvula
Depends upon its o Pillars of the tonsils
classification The pseudomembrane can be
Three (3) Types of Respiratory described as:
Tract Infections o Grayish-white
membrane
1. Nasal Type o Like cigarette ash
Nasal passages are affected
Patient also has a BULL
With irritating nasal discharge
NECK appearance
o Characterized by
o Enlargement of the
serosanguinous
neck
secretion with foul
mousy odor (whitish,
50
o Specifically of the
anterior upper aspect Important Concepts!!!
of the neck Normally, when a person
o This is due to breathes in, the chest
inflammation and expands
enlargement of cervical But with over usage of
lymph nodes accessory muscles, chest wall
o Anterior upper aspect does not expand, rather, it
of the neck is: DRAWS IN!!!
Reddish In order to detect chest
Warm to touch indrawing, look at the
There is pain subcostal area (lower area of
Tenderness the chest region). This
The difference between a elevates due to severe
person with Pharyngeal Type dyspnea
of Diphtheria and a person Do not look at the sternum or
with double chin is that double at the intercostals spaces
chin people have on their Check for chest indrawing
necks: when:
o Normal skin color o The patient is calm
o Normal temperature o The patient is not
o No pain crying
o The patient is not
breast-feeding (chest
indrawing is NORMAL
3. Laryngeal Type under this condition)
Affects the larynx or the voice o The patient is bottle-
box feeding (chest
With hoarseness of voice indrawing is NORMAL
With loss of voice under this condition)
o Aphonia but only Chest indrawing is constant in
temporary a patient with diphtheria
Larynx also serves as airway Chest indrawing is always
passage present in any position in a
o Therefore, there is: patient with diphtheria
Dyspnea
Difficulty Important Concepts!!!
of Pseudomembrane is also
breathing present
Body compensates and uses o Present in the larynx
accessory muscles o Laryngoscope is
needed to see the
Important Concepts! pseudomembranes
Overuse of accessory Pseudomembranes may
muscles results to chest trigger cough
retractions or chest indrawing Characteristics of cough:
51
o Barking cough Confirmatory Test
o Dry o To identify the
o Metallic microorganism
o Croupy o To determine if
o Husky patient is still
Due to hoarseness of voice communicable
Important Concept!
Key Concept! o Patient is still
Laryngeal Type of Diphtheria communicable until
may become severe three (3)
consecutive results
LARNGEAL TYPE OF DIPHTHERIA of negative (-) nose
▼▼▼ and throat culture
Laryngeal Edema are obtained
▼▼▼
Airway Obstruction Medical Management for
▼▼▼ Diphtheria
Respiratory Obstruction Three (3) Objectives:
▼▼▼
Respiratory Distress 1. Neutralize the toxin
▼▼▼ The toxin brings about
Death systemic effects
Therefore, give anti-diphtheria
Therefore, management is toxin
EMERGENCY o Do skin test first
TRACHEOSTOMY o If positive for the skin
Among the three types of test
Diphtheria, Laryngeal Give drug
Diphtheria is the most fatal Because there is
due to the possibility of no Diphtheria Ig
respiratory obstruction, which But give in
may lead to death. fractional doses
Also have ready and handy
Diagnostic Tests for Diphtheria the following:
o Epinephrine
1. Schick’s Test o Corticosteroid
Test for immunity or
susceptibility to diphtheria 2. Kill microorganism
Give anti-biotics
2. Moloney Test Drug of Choice
Test to determine o Penicillin
hypersensitivity to diphtheria Important Concept!
toxin Scraping the
pseudomembrane does not
Nose and Throat Swab kill the microorganism
Most commonly done test It only causes bleeding
52
When the above signs and
3.Prevent Respiratory Obstruction symptoms are observed,
Performance of emergency immediately seek consultation
tracheostomy
2. Maintenance of Patent Airway
Nursing Management for Proper position of patient
Diphtheria o Upright
o Semi-Fowler’s
1. Place patient on complete bed Encourage Deep Breathing
rest until two (2) weeks after Exercises and coughing
recovery exercises with pursed lip
Rationale: Chest Physiotherapy
o To prevent the number Increased oral fluid intake to
one complication – liquefy the secretions
MYOCARDITIS Frequent turning to sides to
o Myocarditis leads to prevent pooling of secretions
death Do inhalation therapy with
o Toxin released by doctor’s order.
microorganism has o Nebulization
special affinity for heart o Steam Inhalation
muscles Perform Postural Drainage
o Toxin released travels with doctor’s order
to the bloodstream If patient cannot expectorate,
o Goes to the heart suction secretions as needed
o Waits for opportunities
when heart’s resistance 3. Provide adequate nutritious diet
to go down: Soft diet due to the presence of
When the heart dysphagia
is overloaded
with work 4. Other nursing managements
When the heart are symptomatic and supportive
is under
stressful Important Concept!!!
activities An attack of diphtheria does
Therefore, provide not provide permanent
COMPLETE BED REST immunity since the causative
agent is a bacteria
Signs and Symptoms of
Myocarditis Preventive Measures
Marked facial pallor
Very irregular pulse rate 1. Immunization
Hypotension DPT vaccine
Chest pain or epigastric pain
Important Concept! 2.Proper disposal of nasopharyngeal
secretions
53
3. Cover the nose and the mouth To loosen thick and tenacious
when sneezing or coughing secretions
Therefore, child coughs for
4. Never kiss the patient. five (5) to ten (10) times
Diphtheria affects all ages When patient is unsuccessful
Common in children in expectorating narrow
passageway requires long
PERTUSSIS inhalation
Also called If patient keeps on coughing
o Whoofing cough o He may choke on his
o Chin cough mucous
Only affects children below six o This results to vomiting
(6) years old o Therefore, the patient
is positive for vomiting
Causative Agent Due to pressure exerted on
Cocobacillus vomiting, there could be
Both aerobic and anaerobic o Congested face
o Bordatella pertussis (bloated face)
o Haemophilus pertussis o Congested tongue
Purple in color
Mode of Transmission Due to pressure
Droplet exerted on the
Manifestations of Pertussis tongue by the
Three (3) Stages teeth when
coughing
1. Catarrhal Stage o Teary-red eyes with
Highly contagious protrusion due to
Colds pressure exerted when
Nocturnal coughing coughing
o Coughing is present at o Distention of face and
night neck veins
Fever o Involuntary micturition
Tiredness and defecation
Listlessness o Abdominal hernia due
to pressure exerted on
2. Paroxysmal or Spasmodic abdominal wall when
Stage coughing
With five (5) to ten (10) If patient is vomiting:
successive, forceful o Metabolic alkalosis
coughings, which ends on a occurs
prolonged inspiratory phase This will trigger convulsions
or a WHOOF due to electrolyte imbalance
To loosen mucous plug on
airway (this causes the patient Convalescent Stage
to cough) Patient is no longer
communicable
54
Signs and symptoms will now Decreases oxygen demand
start to subside Decreases oxygen
Patient is now on the road to consumption
recovery
2. Prevent Aspiration
Diagnostic Tests for Pertussis Proper position of patient
o Upright position in
1. Nasal Swab feeding
During spasmodic attacks of
2. Bordet-Gengou Test cough
Specimen is nasopharyngeal o Hold all feedings and
secretion keep patient on NPO
(nothing per orem)
3. Agar Plates For children below six (6)
Specimen is nasopharyngeal years old:
secretion o If bottle-fed
Inform mother
4. Cough Plate that nipples in
Specimen is nasopharyngeal bottle should
secretion only have a
SMALL BORE to
Medical Management lessen chances
Anti-biotic Treatment of aspiration
o Drug of Choice o Feed child with a
Erythromycin medicine dropper
Pertussis Immune Globulin
For nocturnal cough 3. To manage vomiting:
o Give mild sedation Monitor Intake and Output
Replace fluids and Assess for signs of
electrolytes lost due to dehydration
vomiting Provide proper I.V. regulation
Important Concept!!! Provide adequate fluids with
o No expectorant should extra aspiration precaution
be given to pertussis
patient 4.Application of Abdominal Binder
o This stimulates To prevent abdominal hernia
coughing
o Mucolytics are Important Concept!
allowable No permanent immunity from
an attack of Pertussis is
Nursing Management for acquired. However, second
Pertussis attacks are rare. Age
decreases risks
1. Complete Bed Rest
To conserve the energy of the Preventive Measures
patient Same as for Diphtheria
55
But you can kiss the patient o Eating of the bird is not
because you (adults) are necessary to get
above six (6) years old (in infected
Diphtheria, all ages are Mycobacterium avium
affected) Complex
o Most common
TUBERCULOSIS opportunistic infection
Also called for AIDS patients in the
o Koch’s infection United States
o Phthisis
o Galloping Consumption Important Concept!
o Pulmonary Patients infected with
Tuberculosis Tuberculosis bacilli are most
of the time asymptomatic
Causative Agent Symptoms are usually seen
Mycobacterium tuberculosis after four (4) to eight (8)
o Acid-fast bacteria weeks.
o Also known as tubercle
bacilli Manifestations of Tuberculosis
Afternoon low-grade fever
with night sweats
Mode of Transmission Anorexia
Airborne (most common) Weight loss
Fatigability
Important Concept! Body malaise
Therefore, there is no need to Chest pain / back pain
separate eating utensils! Positive for productive cough
Tuberculosis is not acquired Hemoptysis
through shared utensils. Difficulty of Breathing
Tuberculosis is also acquired Anemia
through ingestion of Amenorrhea in females
contaminated milk
o Causative agent is Three (3) Classifications of
Mycobacterium bovis Patients
or Mycobacterium
bovine 1. According to Extent of Disease
o Tuberculosis of Cattle Basis is on the CAVITATIONS
IN THE LUNGS as seen
o From improperly
through Chest X-ray
pasteurized or
o Minimal Pulmonary
improperly boiled milk
Tuberculosis
Tuberculosis may also be
o Moderately Advanced
acquired from birds
o Mycobacterium avium Pulmonary
Tuberculosis
is the causative agent
o Obtained when taking
care of infected bird
56
o Far Advanced Equipment (PPEs); and
Pulmonary increased body resistance
Tuberculosis through vitamins, adequate
rest and adequate hand
2.According to CLINICAL washing
MANIFESTATIONS
Basis is the presence or TB2
absence of clinical Positive ( + ) to TB exposure
manifestations Positive ( + ) to TB infection
o Active Pulmonary Positive ( + ) to TB testing
Tuberculosis Negative ( - ) to TB symptoms
Infected; with Inactive PTB patients and
signs and carriers are under this
symptoms category
o Inactive Pulmonary They are given prophylactic
Tuberculosis management so that they
Infective; without would not exhibit signs and
signs and symptoms
symptoms; with Start on Anti-Tuberculosis
medication drugs
o INH
o Isoniazid
3.According to American The most
Pulmonary Society effective TB
drug
TB0 Side Effect
Negative ( - ) to TB exposure Peripheral
Negative ( - ) to TB infection Neuritis
Negative ( - ) to TB testing Give Vitamin B6 or pyridoxine
Newborns are under this to counteract INH side effect
classification Increase Vitamin B6 by intake
They are given preventive of:
management in the form of o Beans
BCG vaccine immediately Mongo
after birth Red beans
White beans
TB1 Black beans
Positive ( + ) to TB exposure o Prophylaxis is given for
Negative ( - ) to TB infection six (6) months
Negative ( - ) to TB testing For children
Medical and other healthcare o Prophylaxis is given for
workers are under this nine (9) months
classification For Immunocompromised
They are given preventive patients
management in the form of o Prophylaxis is given for
Personal Protective twelve (12) months
57
o Orange tears
TB3 o Orange secretions and
Positive ( + ) to TB exposure excretions
Positive ( + ) to TB infection o Orange saliva
Positive ( + ) to TB testing o Orange sputum
Positive ( + ) to TB symptoms o Orange feces
Active PTB patients are under Nursing Management
this classification o Inform the patient that
They are given curative
this normally happens
management
o Therefore, remove soft
Combination of Anti-
contact lenses
Tuberculosis drugs to prevent
These may be
drug resistance
permanently
Short-Course Chemotherapy
stained with
o Composed of RIP(E)
orange color
Rifampicin
o Advise the patient to
Isoniazid
use eyeglasses instead
Pyrazinamide
Ethambutol
Isoniazid
May or
Side effect is peripheral
may not
neuritis
be given
Standard Regimen
Nursing Management
o Composed of SI(E)
o Give Vitamin B6 or
Streptomycin
pyridoxine
Isoniazid
Ethambutol
Pyrazinamide
May or PZA
may not Side effect is hyperuricemia
be given Patient is predisposed to
stone formation
Important Concepts!!! Therefore, make urine
Short-Course Chemotherapy alkaline
Side Effects Nursing Management
Causes hepatotoxicity o To alkalinize the urine
Nursing Management
o Increase fluid intake
o Therefore, monitor liver
o Increase intake of
enzyme tests
vegetables
Advise patient to avoid
alcoholic beverages, which
Ethambutol
increase hepatotoxic effects
Side effect is Optic Neuritis
o Causes color blindness
Key Concept!
Rifampicin or inability to
Side effects are: distinguish red from
o Orange urine green
58
Nursing Management If result is CONSISTENTLY
o IMMEDIATELY STOP POSITIVE, it means that the
the medication patient is sensitive to the
because this side effect organism
is IRREVERSIBLE Important Concepts!!!
o This test uses Purified
Important Concepts!!! Protein Derivative or
Standard Regimen PPD
Streptomycin o PPD is administered
o No hepatotoxicity intradermally
o But causes RENAL o Tubercullin testing is
TOXICITY interpreted after forty-
o Nursing Management eight (48) to seventy-
o Monitor the following: two (72) hours
Creatinine levels o A positive result would
Blood Urea give you an induration
Nitrogen (BUN) of greater than ten (10)
levels mm.
Monitor Intake o If patient is positive for
and Output HIV, a positive result
o Also causes would give the patient
OTOTOXICITY an induration of greater
o Nursing Management than five (5) mm
o Assess patient for Three (3) Ways of Performing
tinnitus or ringing of the Tubercullin Testing
ears
o Assess patient for 1.1) Mantoux Test
vertigo, which is Just like a skin test
another sign indicative Utilizes the same technique
of ototoxicity as a skin test
Uses PPD
Key Concept! Interpreted after forty-eight
The American Pulmonary (48) to seventy-two (72) hours
Society classification is the Positive result is bigger wheal
best classification!!! induration
59
This utilizes a special syringe o As the back of tongue
with four (4) small needles for curves upon spitting,
one simultaneous application phlegm goes out
Key Concept!!!
1.3) Vollmer and Pirquet Test o Continuous receipt of
Skin scratch or skin patch test anti-Tuberculosis drugs
Get sterile needle for two (2) weeks will
Get gauze containing PPD give the patient a
Apply this gauze over the negative ( - ) result
scratch or tape this gauze o Therefore, patient is no
over the scratch longer communicable
Keep gauze on for seventy-
two (72) to ninety-six (96) 3. Chest X-Ray
hours Shows extent of lung
Remove after three (3) to four involvement
(4) days Does not reveal causative
Results cannot be interpreted agent
yet Not a confirmatory
Wait for another forty-eight examination
(48) to seventy-two (72) hours
Therefore, results could be Medical Management for
obtained after five (5) to Tuberculosis
seven (7) days!!! Short-Course Chemotherapy
Standard Regimen
Important Concept!
Mantoux Test is the best type Nursing Care for Pulmonary
of test!!! Tuberculosis
o Easier to perform Diet
o Less pain to patient Drugs
o Most accurate results o Most important
Rest
2. Sputum Examination
This is the CONFIRMATORY Important Concept!
TEST for Tuberculosis Do not perform Chest
Done in the morning upon Physiotherapy on PTB patient
rising before oral care This can stimulate or
Collection of Sputum aggravate the following:
o Do deep breathing o Hemoptysis
exercises for three (3) o Frank Bleeding
times
o Open mouth widely Key Concept!
o Put tongue at the back An attack of PTB only gives
of the lower teeth temporary immunity
Preventive Measures
60
1. Immunization (i.e. mother who is
Bacillus Calmette Guerin asymptomatic)
(BCG) vaccine Nursing Management
Number of Doses: o Bring the child to the
o Two health center or clinic
When Given: for INCISION
o 1st Dose – At Birth DRAINAGE
o 2nd Dose – Upon school o Then give prophylactic
entrance INH for nine (9) months
Dosage of First Dose
o 0.05 cc Additional Concepts!!!
Route of First Dose At school entrance
o Intradermal Give booster dose of BCG
Site of First Dose When given:
o Right deltoid muscle o About six (6) to seven
Important Concepts!!! (7) years old
o Do not massage site of Dosage of Booster Dose
injection o 0.01 cc
o Rationale: Route of Booster Dose:
It will spill the o Intradermal
drug Site of Booster Dose
o Child may experience o Left Deltoid muscle
fever Important Concepts!!!
Nursing Management o No abscess formation
o Give paracetamol on site of booster dose
o On site of injection, o Site depends on
there will be an preference of the
abscess formation, mother in a private
which will develop into setting
a scar within two (2) to
three (3) months Preventive Measures (continued)
o If after three (3) 2.Proper disposal of nasopharyngeal
months, abscess is still secretions
present, this is called 3. Cover nose and mouth when
an INDOLENT sneezing or coughing
ABSCESS caused by: 4. Proper pasteurization of milk
Wrong technique
Given PNEUMONIA
subcutaneously Inflammation of the lung
instead of parenchyma
intradermally Caused by several organisms
Child’s
Causative Agents:
exposure to a
Virus
person with TB
o Cytomegalovirus
61
Common about by
opportunistic ASPIRATION
infection in AIDS PNEUMONIA
Protozoa Important Concept!
o Pneumocystis carinii o Lipid Pneumonia
Pneumonia Occurs when oil
Also a common is used in
opportunistic cleaning the
infection in AIDS nose
Bacteria Oil is not
o Most common cause absorbed by the
o Can be caused by lungs
primary infection Therefore, do not use oil-
o Can be secondary to based lubricants in
previous infection: nasogastric tubes.
A complication 4, Productive Cough
A debilitating 5. Presence of Chest Pain or
disease Pleuritic Pain
o Aggravated when
coughing
Mode of Transmission o Use of chest binder is
Droplet encouraged
62
o Cut off is forty (40) o Decreased vocal
breaths per minute fremitus
o If respiratory rate is 41 ‘Ninety-nine’
breaths per minute and verbalized
above, this is indicative o Decreased breath
of Pneumonia sounds
Therefore, if there is fast
breathing, automatically, it is 4. Percussion
Pneumonia Dullness upon percussion
Home management involves
antibiotic therapy Medical Management
Depends on causative agent
Important Concept! If viral
Check for the presence of the o Symptomatic
following: management
o Chest Indrawing If protozoal (PCP)
o Stridor o Drug of choice is
Harsh breath Pentamidine
sound heard If bacterial
during o Administer anti-biotics
inspiration o In the hospital setting,
To check, place drug of choice is
ear on nose or Penicillin
mouth of patient o In the community
o Cough setting, drug of choice
If these three signs are is Cotrimoxazole
present, then there is (administered T.I.D.)
SEVERE PNEUMONIA
Nursing Care for Pneumonia
Diagnostic Tests for Pneumonia Patients
Priority
1. Chest X-ray o Ineffective airway
Expect infiltrations clearance
Lung consolidation Management
This is the confirmatory o Maintain patent airway
examination o Adequate rest
o Adequate nutrition
2. Sputum Examination
Purpose is to know what
Preventive Measures
microorganism brought
1. Immunization
pneumonia
Pneumovax
For prevention of secondary
3. Auscultation
pneumonia
For crackles
Given to adults
For ronchi
63
Given to the elderly with violent diarrhea (which
Community-Acquired occurs continuously)
Pneumonia (CAP)
Mode of Transmission
2. Proper disposal of Fecal – Oral route
nasopharyngeal secretions
Source of Infection
3. Cover the nose and mouth while Food
coughing or sneezing Water
64
o General manifestation Poor skin turgor
is diarrhea Very dry
o Borborygmi is present Nursing Management
Gurgling sound o Patient is placed on a
on the abdomen special bed called the
Typhoid Fever WATEN BED – bed
o Three (3) Clinical with a hole
Features o Pail is positioned
o 1. Rose spots underneath the hole on
This is the the bed
PATHOGNOMONIC o Bed pan is not advised
SIGN for typhoid o Continuous diarrhea
fever makes the bedpan
o 2. Ladder-like fever inadequate in
o 3. Splenomegaly containing all the fecal
Dysentery material
o Characteristics of Stool o Vomiting also
o If Bacillary Dysentery contributes to
Mucoid Stool dehydration
Which could Number 1 indicator of
become blood dehydration in a patient with
streaked if diarrhea is LOSS OF
severe WEIGHT
Microorganism’s o This occurs within or
endotoxin before forty-eight (48)
destroys the hours
intestinal wall Other manifestations of
dehydration, which are seen
o If Cholera after forty-eight (48) hours
Rice-watery are:
stool, which is o Thirst
one after the o Sunken eyes
other o Sunken fontanelles
The o Poor skin turgor
microorganisms
do not destroy Diagnostic Tests for Patients with
the intestinal Gastroenteritis
wall
They only 1. Stool Examination
stimulate Most common diagnostic
peristalsis examination
Rapid dehydration occurs For Typhoid Fever
o Manifested by washer o Stool examination is
woman’s hand not a good test
Decreased skin o Blood examinations are
integrity done
65
o Blood culture is also depression, which
done to identify the leads to anemia and
microorganism even leukemia
o Done during initial In dysentery, particularly
manifestation of the bacillary dysentery, the drug
disease of choice is
In the Philippines, the WIDAL COTRIMOXAZOLE
TEST is done for Typhoid In cholera, the drug of choice
Fever is TETRACYCLINE
o The antigen is detected
o Antigen O Important Concepts on the
Somatic antigen Administration of Tetracycline
If present, the
patient is Tetracycline should not be
positive for given with the following:
infection o Milk or calcium-rich
o Antigen H foods
Flagellar antigen o Antacids
If present, o Iron-preparation
patient has been medication
previously For better Tetracycline
exposed to absorption
typhoid fever or o Give Tetracycline with
immunization one full glass of water
In TYPHIDOT, a blood This drug should not be given
examination is conducted and to children below eight (8)
an antibody is detected years of age because it
causes staining of teeth
2. Rectal Swab This drug is not given to
If patient is positive for pregnant women
gastroenteritis o It is TERATOGENIC to
bone growth of the
Medical Management for fetus because it binds
Gastroenteritis to calcium
Once Tetracycline is expired,
1. Fluid and electrolyte replacement discard it because it will
Oresol increase the toxic effect of the
I.V. fluid drug
Gatorade It must be kept away from
sunlight
2. Antibiotics It must be placed in an amber
In typhoid fever, the drug of bottle
choice is Sunlight destroys component
CHLORAMPHENICOL of tetracycline
o This drug gives rise to
bone marrow Important Concept!
66
Gastroenteritis attack does o Swine Herd’s Disease
not give permanent immunity o Ictero-hemorrhagic
disease
Preventive Management A disease of a low form of
1. Immunization animal found in the farm
CDT immunization
Given only free during RATS
epidemic ▼▼▼
Provides six (6) months Source of Infection
immunity Excreta of Rats
Urine of Rats
2. Avoid the five (5) Fs ▼▼▼
Usual source of infection are Causative Agent (Spirochetes)
the Five (5) Fs: Leptospira canicola
Feces Leptospira interrogans
o Proper excreta (most common in the Philippines –
disposal infects rats)
Food Leptospira hemorragica
o Proper food
preparation Mode of Transmission
o Proper food handling Skin penetration
o Proper food storage Important Concept!
o Avoid eating in No need to have a break in
unsanitary places the skin or to have a wound to
Fingers have leptospirosis
o Hand washing
Flies Individuals who are High-Risk for
o Eradicate Leptospirosis:
o Environmental Sewage Workers
o Those working in
Sanitation
o Insecticide drainage systems
Farmers
o Screening
Miners
Fomites
Slaughterhouse workers
o Do not put anything
(pigs, cattle are sources of
into your mouth infection)
o Most common is the Manilenos
ball pen o Due to flooding
Incidence of leptospirosis
LEPTOSPIROSIS increases during the rainy
Also called season
o Mud Fever
o Swamp Fever Key Concepts!
o Canicola Fever When the microorganism
o Pre-tibia enters, it travels along the
o Weil’s Disease bloodstream
67
It affects other organs
o Striated Muscles Diagnostic Tests for Leptospirosis
o Liver Blood Examinations
o Kidneys o Leptospira
Spirochetes Agglutination Test
have a special (LAT)
affinity here o Leptospira Antigen-
They destroy the Antibody Test (LAAT)
nephrons o Microscopic
o Most common Agglutination Test
complication of (MAT)
Leptospirosis, which Reveals the
brings about death is microorganism
Kidney Failure
Medical Management of
Manifestations of Leptospirosis Leptospirosis
Fever with chills
Presence of intense itchiness Anti-biotics
of the conjunctiva Drug of Choice is
Abdominal Pain TETRACYCLINE
Nausea and Vomiting If patient does not tolerate
Muscle tenderness and pain Tetracycline, give Penicillin
on the calf muscle instead
(gastrocnemius)
o Therefore, the patient Important Concepts on Penicillin
does not like to walk or If given per orem:
stand Give one (1) hour before
For ictero-hemorrhagic type of meals or two (2) hours after
leptospirosis: meals
o Jaundice o It binds with food and
o Hemorrhages on skin becomes digested
and mucous o When this happens, it
membrane will be metabolized and
would have no effect
Important Concept! o Therefore, it is best to
Pathognomonic sign of give Penicillin on an
leptospirosis are the orange empty stomach
eyes or orange sclera of the Do not give with fruit juices or
eyes citrus juices
o These juices destroy
Important Concept! the component of
If the kidney is affected, there Penicillin
would be signs and symptoms o Therefore, give with a
of kidney failure: full glass of water!!!
o Decreased urine output
o Leading to anuria
68
Nursing Management for
Leptospirosis Nursing Care for Mumps Patients
Symptomatic and supportive
Monitor urine output due to 1. Provide Complete Bed Rest
possible kidney failure (CBR) until swelling subsides
Immediately refer to doctor for Rationale:
any signs and symptoms of o To prevent glandular
kidney failure complications:
o In Females:
Preventive Measures Oophoresis or
Eradicate rats by inflammation of
environmental sanitation the ovaries
o Use of rat poison o In Males:
Avoid walking through flooded Orchitis or
areas inflammation of
o Wash with soap and the testes
running water after
walking in floods 2. For males, wear well-fitted
supporters to prevent pulling of
MUMPS gravity on the testes and blood
Infectious parotitis vessels.
Rationale:
Causative Agent o This predisposes the
Paramyxovirus patient to orchitis and
o Found on the saliva of atrophy leading to
the infected individual sterility
69
o If mumps is on the left Mumps attack gives
side, orchitis is also on permanent immunity
the left side When is the person with
o If mumps is bilateral, Mumps communicable?
orchitis is also bilateral o He is communicable
until swelling subsides
3. Provide adequate nutrition o Highly-contagious two
Provide the following types of (2) days after onset of
diet: swelling
o Soft diet
Because there is Preventive Measures
pain upon Immunization
chewing o MMR vaccine
o Bland diet Proper disposal of salivary
Sour and spicy secretions
foods are Cover nose and mouth while
irritating coughing and sneezing
They increase
salivation and
increase pain COMMUNICABLE DISEASES OF
Thus, kalamansi THE GASTROINTESTINAL TRACT
is AND ITS ACCESSORY ORGANS
contraindicated
for mumps HEPATITIS
patients Inflammation of the liver
o Apple juice and water Brought about by several
are allowed in mumps causes:
patients o Alcoholism
o Drug intoxication
4. Apply ice cap or ice cooler to Hepatotoxic
relieve pain Drugs
Cold application deadens the Anti-
nerve endings temporarily Tuberculosis
This results to numbness drugs
Tylenol
Important Concept! Acetaminophen
Aniel (composed of vinegar o Chemical Intoxication
and dye) has a cold effect that Arsenic
decreases pain o Microorganisms
This is colored blue so that Viral
the person with mumps could Communicable
be easily identified while he is microorganisms
still far away
Important Concept!
Key Concept! Current Number of Viruses
causing Hepatitis
70
Capable of Infecting Humans Those who practice anal –
o Hepatitis A virus oral sex
o Hepatitis B virus
o Hepatitis C virus Incubation Period:
o Hepatitis D virus Two (2) to six (6) weeks
o Hepatitis E virus
o Hepatitis G virus HEPATITIS B
Also called:
Non-pathogenic in Man
o Serum Hepatitis
o Hepatitis H
o Homologous Hepatitis
HEPATITIS A o Viral Hepatitis
Also called: The most fatal form of
o Infectious Hepatitis hepatitis
o Catarrhal Jaundice The most fulminant form of
hepatitis
Hepatitis
o Epidemic hepatitis
Causative Agent
Incidence is in
Hepatitis B virus
epidemic
o DNA-containing virus
proportions
Causative Agent
Important Concept!
Hepatitis A virus
In Hepatitis B infected
o RNA-containing virus
individuals
Important Concepts!
o The Blood
In Hepatitis A infected
Harbors the
individuals:
microorganism
o The feces
o Other body fluids
Harbors the
Tears
microorganism
Saliva
in abundant
Sweat
amounts
Cerebrospinal
o The blood
Fluid
Harbors the
Milk
microorganism
Urine
in minimal
Semen
amounts
o In fact, all fluids
Harbor the
Mode of Transmission
microorganism
Fecal – Oral Transmission
Rarely percutaneous or by
Mode of Transmission
blood transmission
Percutaneous
o Use of contaminated
Individuals AT RISK for Hepatitis
A: sharps and needles
Those living in unsanitary o Blood Transfusion
conditions Oral to oral Transmission
o In saliva
71
Sexual Transmission Hemodialyzing patients
o Seminal fluid Healthcare workers
o Cervical fluid Drug addicts
Vertical Transmission Blood Recipients
Swallowing of amniotic fluid
by the baby Incubation Period
Five (5) to twelve (12) weeks
Individuals AT RISK for Hepatitis
B: HEPATITIS D
Healthcare workers Also called
o All who are in contact Dormant Type of Hepatitis B
with body fluids of
patients Important Concepts!
Blood recipients A person must have Hepatitis
Hemodialyzing patients B before he could be infected
Drug addicts with Hepatitis D
Promiscuous individuals with Hepatitis D cannot multiply by
multiple sex partners itself
It cannot bring about infection
Incubation Period If Hepatitis B is present in the
Six (6) weeks to six (6) body, Delta virus activates
months Hepatitis B virus to help the
Delta virus multiply
HEPATITIS C
Also called: Causative Agent
o Post-transfusion Hepatitis D virus
Hepatitis Delta virus
Rationale:
o Because people who Important Concept!
develop this are those In Hepatitis D infected
who have undergone individuals
blood transfusion o Blood
Causative Agent Harbors the
Hepatitis C virus microorganism
o Other body fluids
Important Concept! Tears
In Hepatitis C infected Saliva
individuals Sweat
Blood Cerebrospinal
Harbors the microorganism Fluid
Milk
Mode of Transmission Urine
Percutaneous Semen
o In fact, all fluids
Individuals AT RISK for Hepatitis Harbor the
C: microorganism
72
Mode of Transmission Individuals AT RISK for Hepatitis
Percutaneous E:
o Use of contaminated Those living in unsanitary
sharps and needles conditions
o Blood Transfusion Those who practice anal –
Oral to oral Transmission oral sex
o In saliva
Sexual Transmission Incubation Period:
o Seminal fluid Two (2) to six (6) weeks
o Cervical fluid
Vertical Transmission HEPATITIS G
Swallowing of amniotic fluid No synonyms
by the baby
Causative Agent
Individuals AT RISK for Hepatitis Hepatitis G virus
D:
Healthcare workers Important Concept!
o All who are in contact In individuals with Hepatitis G
o The Blood
with body fluids of
patients Harbors the
Blood recipients microorganism
Hemodialyzing patients
Drug addicts Mode of Transmission
Promiscuous individuals with Percutaneous
multiple sex partners
Individuals AT RISK for Hepatitis
Incubation Period G:
Three (3) weeks to twelve Hemodialyzing patients
(12) weeks Healthcare workers
Drug addicts
HEPATITIS E Blood Recipients
Also called
o Enteric Hepatitis Incubation Period
Unknown
Causative Agent
IMPORTANT CONCEPTS!!!
Hepatitis E virus
Similar Types or Partner Types
Hepatitis A and Hepatitis E
Important Concept!
Hepatitis B and Hepatitis D
In individuals with Hepatitis E
Hepatitis C and Hepatitis G
o The Feces
Harbors the
Manifestations of Hepatitis
microorganism
Three (3) Stages
Mode of Transmission
1st Stage – Pre-Icteric Stage
Fecal – Oral route
73
This occurs before jaundice arises one hundred twenty
The patient experiences: (120) days
1. Fever End-product of RBC
o Due to infection breakdown is bilirubin
2. Right Upper Quadrant pain o Accumulation of
o Due to inflammation bilirubin into the system
and infiltration of the leads to the 2nd Stage –
liver Icteric Stage
3. Fatigability
4. Weight Loss 2nd Stage – Icteric Stage
5. Body Malaise Patient exhibits:
o The three (3) Jaundice
manifestations above o Due to inability of the
are due to the inability liver to eliminate
of the liver to convert normal amounts of
glucose to glycogen bilirubin
o Body compensates by o Body compensates by
breaking down protein eliminating bilirubin
o End-product of protein through sweat
breakdown would be Pruritus
amino acids o Due to accumulation of
o Amino acids are bile salts in the skin
normally deaminated Tea-colored Urine or Brown-
by the liver so that they colored Urine
could be eliminated o Due to excess bilirubin
6. Anorexia thrown out by the
7. Nausea kidney in the urine
8. Vomiting Acholic Stool or Clay-colored
o Above three (3) Stool
manifestations are due o Due to absence of
to inability of the liver to bilirubin (conjugated
deaminase proteins bilirubin) that normally
Anemia goes to the duodenum
Paleness to color the stool
Pallor Hepatomegaly
o The above three (3) o Enlargement of the
manifestations are due liver
to decreased life span o Due to an overworked
of Red Blood Cells liver
(RBC) Important Concept!
o Normal live span of o Viral infections are self-
RBCs is one hundred limiting
twenty (120) days If no complication arises, this
o In hepatitis patients, would lead to the 3rd Stage –
RBCs live for less than Post-Icteric Stage
74
3rd Stage – Post-Icteric Stage Formerly SGOT
Jaundice disappears Serum Glutamic-Oxaloacetic
Signs and symptoms subside Transaminase
Energy level increases Increases only upon the onset
Patient is on the road to of jaundice
recovery
Important Concept! 1.3) ALP
o It takes three (3) to four Alkaline Phosphatase
(4) months for the liver Increase indicates:
to regenerate or o Obstructive Jaundice
recover o Obstructive Hepatitis
o Physician usually o Obstruction in the
advices rest for Biliary Tract
complete liver recovery
or regeneration 1.4) GGT
Most important Health Gamma Glutamyl Transferase
Teaching: When increased
o Avoid alcohol for a o Patient is experiencing
period of one (1) year TOXIC HEPATITIS
o Avoid over the counter Due to toxic
drugs (OTCs) that are substances
hepatotoxic for one (1) Alcohol
year Hepatotoxic
o Consult physician prior agents
to use of over the
counter drugs. 1.5) LDH
Lactate Dehydrogenase
Diagnostic Tests for Hepatitis When identified, it indicates
liver organ damage
1. Liver Enzyme Tests
Tests for extent of liver 2. Serum Antigen-Antibody Test
damage for Hepatitis
75
HBeAg Inhibits
Protein-independent Antigen multiplication of
Anti-HBe the virus
o Cost:
2.4) For Hepatitis C Approximately
HCsAg Php200 / tablet
Hepatitis C Surface Antigen 2) BRM
Anti-HCs o Biologic Response
Modifiers
Medical Management of Hepatitis o An immunomodulating
No specific treatment drug
Treatment is symptomatic as o Interferons
causative agent is a virus Injectable form
of BRM
Most Common Drugs used in Normal
Hepatitis: substance
Essentiale produced by the
Jetipar body when virus
Silymarine enters the
o The above three (3) human cell
drugs are: o Dosage:
Hepatic Two (2) to three
protectors (3) times a week
Composed of for six (6)
multivitamins, months
phospholipids o Action:
and nutrients Kills the virus
needed by the o Cost:
body so that the
Approximately
liver would not
Php85,000!!!
be overworked
and be relaxed,
and thus,
Nursing Care for Hepatitis
recover
Two (2) Important Aspects
Latest Trend in Pharmacological
1. Provide Complete Bed Rest
Management of Hepatitis
(CBR)
Utilizes a combination of:
To promote liver regeneration
1) Lamivudine
and recovery
o Anti-viral drug
When rested, there is
o Dosage: decreased metabolism
Once daily for Less metabolism leads to
one year decreased liver load
o Action: Liver relaxes and liver
recovers
76
2. Diet years, the patient would
Low fat diet develop cancer of the liver or
o Because there is not cirrhosis of the liver
enough bile released or
produced by the liver Preventive Measures for Hepatitis
Increased Carbohydrate
Intake 1. Immunization
o To spare protein Hepatitis B vaccine
metabolism Number of Doses:
o To decrease amino o Three (3)
acids Interval between doses:
o Accumulation of protein o Four (4) weeks
breakdown products When given:
like ammonia would o 1st Dose – Six (6)
lead to hepatic weeks from birth
encephalopathy o 2nd Dose – Ten (10)
weeks from birth
Butterball Diet o 3rd Dose – Fourteen
o Produces energy (14) weeks from birth
o These are hard Dosage:
candies o 0.5 cc
o Chocolates are Route:
contraindicated o Intramuscular
They contain fat Site:
Protein Intake o Vastus lateralis
o Depends on the Important Concepts!!!
situation o Inform the mother that
o If the patient is infected there would be pain
Provide and soreness on the
moderate injection site
protein intake o A slight elevation on
o If the patient is in the liver enzyme tests is a
recovery stage NORMAL REACTION
Provide to the vaccine
increased
protein intake 2. Avoid the different modes of
o If complications arise transmission
Provide For Hepatitis B, C, and D
decreased o Blood-borne diseases
protein intake There is a Needle-exchange
Program in the United States
Key Concept! and in Australia
The most fatal form of o Every 6:00 PM a
hepatitis is HEPATITIS B! healthcare worker is
Even if patient recovers, after given a knapsack with
twenty (20) or thirty (30) needles and sharps
77
o He then proceed to o Signs and symptoms
areas of distribution – develop at a later stage
alleys
o Exchanges new Manifestations of Gonorrhea
syringes with old
syringes used by drug In males:
addicts. Burning pain, burning
sensation upon urination
COMMUNICABLE DISEASES OF o Due to redness and
THE GENITOURINARY SYSTEM – edema of urinary
SEXUALLY TRANSMITTED meatus brought about
DISEASES by acidic urine
Prostatitis
Bacterial o Abscess formation on
Gonorrhea the prostate gland
Syphilis Purulent Discharges
o Mostly abundant in the
Viral morning
HIV Infection If gonorrhea is persistent, a
AIDS scar develops on the
EPIDIDYMIS
GONORRHEA o Scar obstructs the flow
Also called of the sperm cells
Clap Sterility
Microorganism resembles o Due to obstruction of
hands clapping together sperm cell flow
Strain
Gleet
Jack
GC In females:
Morning Drop Burning sensation upon
urination if urinary meatus is
Causative Agent involved
Neisseria gonorrhea o Urinary meatus is
seldom involved in
Mode of Transmission gonorrhea.
Sexual contact o Cervix is usually the
Important Concepts!
one that is affected
o Most of the time,
Presence or absence of
MALES are infected purulent discharges
Urethra are Important Concept!
affected leading o If there is no burning
to urethritis
pain and no purulent
Females can also be infected
discharge, the patient
o Cervix is affected
may not know that she
is infected
78
o Presence of abscess Presence of
formation on the Gonococcal
Bartholin’s Gland or the Rashes
Skeene’s Gland Papular
o When this abscess Elevated
goes up, it gives rise to Rashes
ENDOCERVICITIS or Pustular
ENDOMETRITIS With pus
Hypogastric Pain May be necrotic
o Due to presence of gonococcal
endocervicitis or rashes
endometritis Polyarthritis develops
Important Concept! Tenosynovitis
o Either of Endocervicitis o Tendons and synovium
or Endometritis could are affected
give rise to Pelvic Important Concept!
Inflammatory Disease o Effect of disease to
o Pelvic Inflammatory child of mother with
Disease gonorrhea:
A systemic Opthalmic
disease neonatorum
characterized o Management:
by: Give CREEDE’S
Fever PROPHYLAXIS
Severe to prevent
abdominal blindness in the
pain newborn
Nausea Diagnostic Tests for Gonorrhea
and
Vomiting 1. Culture and Sensitivity
This is Collect urethral discharges
secondary Done by scraping mucosa of
to the urethra
gonococcal 2. Papanicolau’s Smear or Vaginal
infections Smear
Sterility and Ectopic For females
Pregnancy
o If gonorrhea persists, it Medical Management of
causes a narrowing of Gonorrhea
the Fallopian Tube
Gonococcal Septicemia 1. Anti-biotics
o Occurs when Drug of Choice
o Penicillin
gonorrhea is already
systemic o Benzathine Pen G
o Signs and symptoms (Penadur)
would include:
79
o Given also to Key Concept!
Rheumatic Heart o If the patient is
Disease patients Pregnant
Important Concepts!!! Sensitive to
o Penicillin G is NEVER Penicillin
GIVEN PER I.V. o Administer
o For I.M. use only SPECTINOMYCIN
o Rationale: instead!!!
If given per I.V., Key Concept!
it will KILL THE o If patient with
PATIENT!!!! gonorrhea has
It is oil based chlamydial infection or
It forms into an vice versa (Gonorrhea
EMBOLUS that and Chlamydia are
would kill the TWIN SISTERS)
patient Do not give
o When given per I.M. Penicillin
Use big gauge Do not give
needle Spectinomycin
Gauge 16 – 18 o Administer
This drug easily DOXYCYCLINE
coagulates instead!!!
This drug easily
clots Nursing Care for Patients with
Therefore, Gonorrhea
administer this Gonorrhea patients are not
drug QUICKLY confined
Dilute with one They are treated on an
(1) cc of outpatient basis
LIDOCAINE
One cubic 1. Psychological Aspect of Care
centiliter (1cc) of STD patients have low self-
Lidocaine plus esteem
four (4) cubic
centiliters of 2. Health Education and Patient
Plain Normal Teaching
Saline Solution To prevent recurrence of
is used to infection
provide less
pain Preventive Measures
o Rationale: Safe Sex
Due to the According to the Center for
incorporation of Disease Control, “safe sex”
an anesthetic in means:
the form of o No sex
Lidocaine
80
o Mutual monogamous o Painless popular
relationship lesions that heal
o Mutual masturbation spontaneously without
without direct contact treatment
Holding of body o Found on the:
parts but no sex Genitals
Important Concepts! Face
o Condom is not an Lips
example of safe sex Tongue
o Condom use is not Under the
100% guaranteed in breasts
preventing infection On fingers
o Best way to prevent o If without treatment,
spread of infection is chancre disappears, it
through BEHAVIOR will signal the start of
MODIFICATION the Secondary Stage
o Also called LOW-RISK
Behavior Secondary Stage of Syphilis
Patient exhibits:
SYPHILIS Flu-like symptoms
Also called: o Sore throat
o Pox o Headache
o Lues o Fever
o Sy Several forms of dermatitis
o Bad Blood Disease o Rashes (Kulugo)
All over the body
Causative Agent o Presence of dry, hard
Treponema pallidum wart-like lesions
Mode of Transmission Condylomalata
Sexual Contact o Infectious lesions that
May be transmitted vertically are fused together
o May pass placental o Found under the breast
barrier after sixteenth and on the genitals
(16th) week of o Highly infectious
pregnancy lesions
Rarely transmitted thorough
Blood Transfusion Key Concept!
o Secondary Stage is
Manifestations of Syphilis highly infectious
Three (3) Stages o Also called Infectious
Stage
Primary Stage of Syphilis Changes in hair growth
Patient exhibits: o Patchy Alopecia all
Chancre over
o Characteristic lesion
81
o Patient has MOTH- Diagnostic Tests for Syphilis
EATEN APPEARANCE
Affects growth of pubic hair 1. Culture and Sensitivity
o Thinning of pubic hair Done by mucosal scraping
o Management:
Patient uses 2. Dark Field Microscopy
aloe vera
Patient uses 3. Blood Examination
Mane and Tail
Key Concept!!! 3.1) FTA-ABS
o Before the Tertiary Fluorescent Treponema
Stage of Syphilis Antibody Absorption Test
occurs, the patient o This is the confirmatory
becomes test for syphilis
ASYMPTOMATIC
o This may be called the 3.2) VDRL
LATENT PHASE Venereal Disease Research
A transition Laboratory
period of one (1) o This is not a definitive
to two (2) years. test
82
o When given I.M. Baby has nasal
Diluent used is discharges
Xylocaine Mother may NOT give birth to
Important Concepts!!! a child with syphilis but may
o Do NOT give birth to a child with LATE
INTERCHANGE SYPHILIS
diluents! o Two (2) years after
o If I.M. preparation is birth, the child will
given via I.V. manifest:
Patient dies due Hutchinson’s
to dysrhythmias Teeth
o If I.V. preparation is Saw-like
given via I.M. teeth
Viscous Anterior Bowing
medication of the Tibia
would give rise Fractured
to pain upon Tibia
administration Backward
Tibial
Nursing Management in Syphilis growth
Same as in gonorrhea Saddle nose
with high palate
Preventive Management of Deafness
Syphilis Persistence of
Same as in gonorrhea dactylitis
o If child with Late
Important Concepts!!! Syphilis is not given
Effect of syphilis to child prophylaxis upon
whose mother developed adolescence
syphilis during pregnancy: Child develops
o Still Birth (baby dies) neurosyphilis
o Syphilitic Baby Child will
Placenta is eventually die
bigger than the Mother may NOT give birth to
baby a child with syphilis
Baby resembles o Child may be born
the appearance NORMAL
of an old man o Child may be ALIVE
Baby has linear and NORMAL
scars at angles o But wait for two (2)
of the mouth years to really declare
Baby has that child is normal
persistent
vesicular Important Concepts!!!
eruptions or If you are pregnant, do not be
blisters infected with syphilis
83
Do not get infected with Therefore, AIDS
syphilis, particularly in the cannot be
third (3rd) trimester of acquired
pregnancy. through the
The nearer you give birth to a swimming pool
child, the greater is the o By Ordinary House
chance that the child would Bleaching Soap with
develop congenital anomalies Sodium Hypochlorite
Zonrox
ACQUIRED IMMUNE DEFICIENCY Chlorox
SYNDROME (AIDS) Purex
Domex
Important Concept!!! Proportion of
Acquired Immune Deficiency bleaching soap
Syndrome (AIDS) is to water is 1:10
DIFFERENT from HIV Important Concepts!
Infection o If virus leaves the body
of an individual infected
HIV Infection with AIDS (i.e. through
Means that you are infected the semen), the virus
with the virus will survive for only four
Initial stage of AIDS (4) hours
AIDS o If it does not penetrate
Means that you are infected another person, the
You manifest a group of signs virus WILL DIE
and symptoms o But if the virus goes out
With decreased or weakened with blood, the VIRUS
immune system WILL REMAIN ALIVE,
This is the end-stage of HIV as long as the BLOOD
infection IS FRESH!!!
Key Concepts! o Once a person dies
All patients with HIV infection with AIDS, the virus
will develop into AIDS remains in the body of
All AIDS patients have passed the individual, as long
through the HIV stage as, the body is HUMID
Causative Agent o Therefore, the body of
Human Immuno-Deficiency Virus
an AIDS victim should
A Retrovirus
be cremated within
A very fragile virus
twenty-four hours after
Can easily be destroyed by:
death or sealed in a
o Seventy percent (70%)
metal coffin, also within
alcohol twenty-four (24) hours
o A temperature of fifty- from death.
six degrees Celsius o The body of an AIDS
(56°C) victim COULD NOT BE
o Chlorine EMBALMED
84
The virus will o Therefore, child is
INFECT THE positive for HIV but
EMBALMERS may this may not mean
the child is infected
Modes of Transmission Child is given up to eighteen
(18) months for HIV testing
Blood Transfusion per Single o After eighteen (18)
Exposure months, child must be
Single Blood Transfusion negative for HIV testing
o Provides 90% chance o If child is still positive
of infection for HIV testing after
eighteen (18) months,
Sexual Contact then the child is
Pandemically, the number one REALLY INFECTED!!!
mode of transmission
o Single exposure gives NORMAL IMMUNE RESPONSE
0.1% to 1.0% chance
of infection Microorganism
o However, due to ▼▼▼
repeated sexual Detected by the Macrophages
encounters, chance of ▼▼▼
infection increases Macrophages will alert T cells
▼▼▼
Contaminated Sharps and Alerted T cells reproduce and
Needles multiply
Single exposure gives 0.1% to ▼▼▼
0.5% chance of infection T cells stimulate the B cells
▼▼▼
Vertical Transmission B cells reproduce and multiply
From the infected mother to ▼▼▼
the unborn fetus B cells release the antibody
o Gives 30% chance of ▼▼▼
infection Antibody produced attacks the
invading microorganism
Important Concepts!!! ▼▼▼
If a child is born to a mother Antigen-Antibody reaction occurs
who is HIV positive, the child ▼▼▼
would ALWAYS have a Manifestation of Disease will be
POSITIVE RESULT for HIV present
TESTING
o HIV testing identifies Important Concept!
the presence of In HIV Infection, there is an
antibodies in the blood alteration in the NORMAL
Child possesses maternal Immune Response
antibodies
HIV (Retrovirus)
85
Has special affinity for T cells As the body takes more time
▼▼▼ to develop antibodies to the
Retrovirus is NOT DETECTED by HIV, the person BECOMES
the Macrophages INFECTED but REMAINS
▼▼▼ ASYMPTOMATIC
Macrophages will NOT BE ABLE TO
ALERT the T cells A WELL-WORRIED INDIVIDUAL
▼▼▼ ▼▼▼
Retrovirus ENTERS the T cell ▼▼▼
▼▼▼ ▼▼▼
Retrovirus releases the enzyme Infected with HIV but is
REVERSE TRANSCRIPTASE ASYMPTOMATIC
This resembles the genetic make-up ▼▼▼
of the T cell ▼▼▼
▼▼▼ ▼▼▼ After six (6) weeks to six (6)
T cell does not destroy the virus ▼▼▼ months (called the WINDOW
▼▼▼ ▼▼▼ PERIOD or the time interval
T cell BECOMES a PRO-VIRUS ▼▼▼ between the infection of the
▼▼▼ ▼▼▼ individual to the production of
Virus multiplies within the T cell ▼▼▼ the antibodies), where the
▼▼▼ ▼▼▼ body produces antibodies
T cell is DAMAGED ▼▼▼
▼▼▼ ▼▼▼
Virus will retrovert before leaving the ▼▼▼
T cell ▼▼▼
▼▼▼ ( + ) for HIV infection
Virus leaves T cell With AID Related Complex (ARC)
▼▼▼ Symptoms
Virus attacks another T cell ▼▼▼
▼▼▼ ▼▼▼
Net effect: No T cells will be present ▼▼▼ Months to years
to stimulate the B cells ▼▼▼
▼▼▼ ▼▼▼
No B cell stimulation ACQUIRED IMMUNE DEFICIENCY
▼▼▼ SYNDROME (AIDS)
No antibody production ▼▼▼
▼▼▼ ▼▼▼
No antigen-antibody reaction occurs ▼▼▼ Months to years
▼▼▼ ▼▼▼
Person is infected but remains ▼▼▼
asymptomatic DEATH occurs
86
Fever with night sweats Continually multiplying and
without a cause continually growing mouth
o All laboratory works are sores
negative
Enlargement of lymph nodes Important Concepts!
without a cause False-Negative Result for
o All laboratory works are AIDS
negative o No antibodies are
Fatigability identified but patient is
Weight Loss already infected
Altered Sleeping Patterns o This occurs during the
Temporary Memory Loss WINDOW PERIOD
Altered Gait The person who undergoes
HIV testing undergoes
Manifestations of AIDS counseling
For adults o This person should not
o Two (2) major engage in any of the
symptoms modes of transmission
o One (1) minor of AIDS before the
symptom window period ends
For Children The ACTIVE PARTNER
o Two (2) major o Considered the GIVER
symptoms o Has less chances of
o Two (2) minor becoming infected
symptoms The PASSIVE PARTNER
o Considered the
Major Symptoms RECEIVER
Fever: One (1) month and o Has greater chances of
above in duration and is being infected
recurrent AGAIN, DO NOT ENGAGE in
Diarrhea: One (1) month and any of the modes of
above transmission of AIDS
Ten percent (10%) weight loss DURING the WINDOW
o Staunted growth in PERIOD!!!
children
Minor Symptoms
Persistent generalized Important Concepts!!!
lymphadenopathy If an adult manifests the
Generalized pruritic dermatitis following:
Persistent cough: One (1) o Two (2) major
month and above symptoms
Oropharyngeal Candidiasis o One (1) minor
Recurrent Herpes Zoster symptom
Progressive Disseminated o Then, that adult is
Herpes Simplex AIDS BONAFIDE
87
If a child manifests the Enzyme-Linked
following: Immunosorbent Assay
o Two (2) major o This is only a
symptoms SCREENING TEST for
o Two (2) minor AIDS
symptoms
o Then, that child is AIDS 2. PCR Test
BONAFIDE Polymerase Chain Reaction
Test
Key Concepts! o Likewise, a
When a person has AIDS, all SCREENING TEST for
microorganisms entering his AIDS
body gives rise to infections o Relatively expensive
These are called o Costs approximately
OPPORTUNISTIC Php5,000 to Php7,000
INFECTIONS per test
In the Philippines, the Number o Results are known
One Opportunistic Infection is within two (2) to three
TUBERCULOSIS (3) hours
88
Indicates HIV Tastes
infection sour
If greater Give
than or together
equal to with fruit
200 juice
Indicates AIDS o Lamivudine
If less o Stavudine
than 200
2.Non-nucleoside Reverse
Medical Management for AIDS Transcriptase Inhibitors
Symptomatic management as Non-NRTIs
virus is the causative agent o Delavirdine
Latest Trend in o Nevirapine
Pharmacologic Management
of AIDS 3. Protease Inhibitors
o COCKTAIL DRUGS PIs
Patient must o Saquinavir
take medication o Indinavir
composed of at o Pitonavir
least twenty-one
o Delfinavir
(21) tablets per
day
Important Concept!
Patient spends
All of the abovementioned
approximately
drugs inhibit multiplication of
Php1,000 per
the virus but DOES NOT KILL
day on drugs
THE VIRUS
Prevents
multiplication of
Nursing Care for AIDS
the virus but
Symptomatic as causative
DOES NOT
agent is a virus
KILL THE
Psychological Care
VIRUS
Promotion of Homeostasis
1.Nucleoside Reverse
Transcriptase Inhibitors
NRTIs
Important Concept!
o AZT Azidothymidine
Role of the Nurse in AIDS
Retrovir
o A counselor
Zidovudine
o ddc
Preventive Measures
Dideoxycitidine
A for Abstinence
Zalcitadine
B for Be Truthful
o ddI
C for Condom use
Dideoxyinosine D for Do not use Drugs
Didanosine
Important Concept!
89
Virus can be found on all body
fluids but will not be enough to
cause infections
Example:
o Six (6) to eight (8)
gallons of saliva are
needed to transmit HIV
90