Male Genital Tract

Q.1) What is the most important cause of squamous cell carcinoma of the bladder?
A. Schistosoma
B. E. coli
C. Candida
D. Genetics
E. none of the above

Q.2) A patient presents with dysuria, increased frequency and urgency, low back and pelvic
pain, fever chills, with loss of sex drive and painful erections and ejaculations. He has
infection of the prostate. What is the most common cause of acute prostitis?
A. E. coli
B. Strep.
C. Staph
D. Fungi
E. None of the above

Q.3) A patient presents with an enlarged prostate gland that is not premalignant.
Micrscopically, there is an increased proliferation of stromal and epithelial cells. Corpora
amylacea are also seen. The patients complains of difficulty starting or stopping urination,
with dribbling, nocturia, and fullness of bladder. Which of the following is decreased in this
patient? BPH!!
A. testosterone
B. estrogen
C. pancreatic enzymes
D. none of the above
E. all of the above

Q.4) A patient presents with hematuria, and bone pain in the back. Like the previous
patient, he also has dysuria and interrupted urine flow. He is diagnosed with prostate cancer.
What is the most important marker of his disease?
A. PSA
B. BRCA1
C. None of the above
D. All of the above
E. Who cares
Q.5) __________ gene is affected.
( 1 word )

Possible correct answers:

 RNASEL

Q.6) Is serum PSA cancer specific?

A. No, it is also found in hyperplasia and prostitis
B. yes
C. not sure
D. who cares
E. all of the above

Q.7) Poorly differentiated sheets and nests are seen in grade ________ and well
differentiated glands are seen in grade ____________.
( 1 word )
Possible correct answers:
 5, 1

Q.8) Metastatic disease is stage _____ and extension outside the prostate is stage_______.
( 2 words )
Possible correct answers:
 DC

Q.9) A fetus presents with only one testes because the other one has not completely
descended. The baby has Pader Willi syndrome. Microscopically, there is leydig cell
hyperplasia and hyalinised tubules. The patient has an increased risk of which of the
following?
A. prostate cancer
B. seminoma of the testes
C. gynecomastia
D. all of the above
E. none of the above
Q.10) A patient presents with a unilateral testicular mass and feeling of heaviness in the
scrotum. He also has hydrocele of the testes. AFP levels are normal, however, the HCG levels
are increased. Grossly the tumor appears as a tan lobulated mass. What is a key microscopic
feature seen in this tumor?
A. fried egg appearance
B. polygonal cells
C. spindle shaped cells
D. none of the above
E. all of the above

Q.11) A 2 year old child presents with a well demarcated tumor with cuboidal columnar
cells in sheets and papillae, called Schiller duval bodies. Which of following levels are
increased?
A. Hcg
B. afp
C. alpha1antitrypsin
D. rbc
E. giant cells

Q.12) Stage 2 represents metastasis to retroperitoneal nodes below the _ whereas Stage _
represents metastasis beyond the retroperitoneal nodes
( 1 word )
Possible correct answers:
 diaphragm; 3

Q.13) Malformation of the urethral groove and urethral canal at the ventral surface is _____
and at the dorsal surface is ______.
( 2 words )

Possible correct answers:

 hypospadias; epispadias

Q.14) A Chinese male is diagnosed with a cancer on the frenum of his penis. The lesion is
cauliflower like in appearance. What is the mode of metastasis?
A. lymphatics
B. hematogenously
C. peritoneum
D. none of the above
E. all of the above
Q.15) Chimney sweepers and coal tar is associated with ________ cancers.
( 1 word )

Possible correct answers:

 scrotal

Q.16) Filariasis causes ________ and __________.

( 4 words )

Possible correct answers:

 chylocele and scrotal elephantitis

Q.17) A tight prepucial ring of scar tissue preventing the foreskin over the penis is
_________ whereas the forced retraction of the phimotic prepuce is _________ .
( 2 words )

Possible correct answers:

 phimosis; paraphimosis

Q.18) A patient presents with painful tense testes. He has TB. With time progresses, the
testes atrophied and underwent fibrosis. The located that the infection started off in was the
____________ .
A. testes
B. scrotum
C. epidydimis
D. prostate
E. none of the above

Q.19) A patient with painless enlargement of the testes, would have _________ in the
seminiferous tubules, as a result of autoimmune attack.
( 1 word )

Possible correct answers:

 granulomas