Professional Documents
Culture Documents
Presumptive Treatment / At Risk Populations Additional diagnostic testing for cause of organ failure
and site of infection
The patient populations listed below may manifest ABG
infection in atypical ways. Consider treatment for sepsis if Basic Metabolic Panel
acutely decompensating. Blood and Urine Cultures
CBC with diff.
Abdominal Pain / Distention Glasgow Coma Scale, RASS
Indwelling medical device or IV lines INR, PT
Altered mental status Lactate
History of recent chemotherapy LFT
History of organ transplant Urine Output
Elderly with unclear etiology of illness
Immunosuppressive status Narrow antibiotic treatment as soon as
source/organism is identified (see ASP Infection
Initial Management Phase (First 24 hours) by site antibiotic grid and the Multi-drug Resistant
Organism (MDRO) treatment table)
History and Physical Remove central line as soon as possible following
Source control (remove and address infection positive cultures for Staphylococcus aureus, gram-
source) negative bacteria or yeast blood stream infection
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