MCB ch 5
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1. What advantage do the cristae
confer on the mitochondria?
A) They allow the mitochondria
to shrink.
B) They greatly increase the
surface area for aerobic
respiration machinery.
C) They confer resiliency on the
cells.
D) They allow swelling of
mitochondria.
E) They activate the matrix
2. When fusion of mitochondria
becomes more frequent than
fission, the mitochondria
tend to become __________.
A) more elongated
B) more interconnected
C) more numerous
D) more distinct
E) more elongated and more
interconnected
3. The presence of Ca
2+
ion transport molecules in the
inner mitochondrial membrane
is
consistent with the
mitochondrion's role in _______.
A) muscle contraction
B) regulating cytosolic Ca
2+
ion concentration
C) ATP manufacture
D) ADP manufacture
E) control of membrane fusion
4. Mitochondria are sites of the
__________.
A) synthesis of certain amino
acids
B) synthesis of heme groups
C) uptake of Ca
2+
ions
D) release of Ca
2+
ions
E) All of these are correct.
They greatly increase the 5. Which of the following regulate both endoplasmic
surface area for aerobic intracellular levels of Ca reticulum and
respiration machinery. 2+ mitochondria
ions?
A) Golgi apparatus
B) ribosomes
C) endoplasmic reticulum
D) mitochondria
E) both endoplasmic reticulum and
mitochondria
6. The inner boundary membrane is proteins responsible
particularly rich in which of the for the import of
more elongated and more following? mitochondrial proteins
interconnected A) protons
B) proteins responsible for the
import of mitochondrial proteins
C) Krebs cycle enzymes
D) enzymes of the glycolytic
pathway
E) glycosaminoglycans
7. What evidence suggests that the 1
outer mitochondrial membrane has
regulating cytosolic Ca evolved from the
2+ outer membrane that is present as
part of the cell wall of certain
bacteria?
1) the presence of porins in both
membranes
2) the virtual absence of
cholesterol from both membranes
3) both membranes being rich in
cardiolipin
4) both membranes being rich in
diphosphatidylglycerol
A) 1
B) 2
C) 3
...
D) 4
E) 1 and 4
8. From what does the mitochondrial 4 12. What happens to the carbons of pyruvate They are
RNA polymerase appear to have that do not enter the Krebs cycle? converted to
evolved? A) They are converted to carbohydrates. CO2
1) the multisubunit RNA polymerase B) They are converted to CO2.
found in prokaryotic cells C) They are converted to glucose.
2) the multisubunit RNA polymerase D) They are converted to ATP.
found in eukaryotic cells E) They are converted to carbon monoxide
3) the multisubunit RNA polymerase (CO).
found in bacterial viruses
13. What molecule is responsible for conveying ...
(bacteriophage)
2 carbons from pyruvate to the Krebs
4) the single subunit RNA
cycle?
polymerase found in bacterial
A) Coenzyme G
viruses (bacteriophage)
B) Coenzyme A
A) 1
C) Acetate
B) 2
D) pyruvate
C) 3
E) oxaloacetate
D) 4
E) 1 and 2 14. Which component involved in the Krebs ...
(TCA) cycle is bound to the inner
9. In what ways can pyruvate and aerobic processes
mitochondrial membrane?
NADH be metabolized? using Krebs cycle,
A) oxaloacetate
A) fermentation, hydrolysis of PGAL fermentation
B) acetyl CoA
B) condensation of PGAL and
C) succinate dehydrogenase
fermentation
D) succinate
C) aerobic processes using Krebs
E) succinyl CoA
cycle, fermentation
D) anaerobic processing using Krebs 15. Where are most of the enzymes of the ...
cycle, fermentation Krebs cycle located?
E) aerobic processing using Krebs A) in the intercristal space
cycle, hydrolysis of PGAL B) on the cristae
C) on the ribosomes
10. How many carbons from 13 original 52
D) in the soluble phase of the mitochondrial
glucose molecules enter the Krebs
matrix
cycle in the
E) in the intermembrane space
presence of oxygen?
A) 0 16. To what is the 2-carbon fragment of acetyl oxaloacetate
B) 13 CoA added to make citric acid at the start of
C) 26 the Krebs cycle?
D) 52 A) oxaloacetate
E) 78 B) citric acid
C) succinate
11. How many carbons from 13 original 0
D) -ketoglutarate
glucose molecules enter the Krebs
E) isocitric acid
cycle in the
absence of oxygen? 17. What is the terminal electron acceptor of O2
A) 0 the electron transport chain?
B) 13 A) water
C) 26 B) O2
D) 52 C) CO2
E) 78 D) CO
E) glucose
18. What is the name of the process by chemiosmosis 23. What is the final electron acceptor in ...
which the electron transport chain the electron transport chain?
generates the A) water
electrochemical gradient that drives B) carbon dioxide
ATP production in the mitochondrion? C) carbon monoxide
A) osmosis D) hydrogen
B) diffusion E) oxygen
C) facilitated diffusion
24. What is formed when electrons reach water
D) chemiosmosis
the bottom of the mitochondrial
E) frusion
electron transport
19. On average, how many ATPs would 24 chain and bind to the final electron
be made if 4 NADH and 6 FADH2 acceptor?
molecules A) water
donated their high-energy electrons B) carbon dioxide
to the mitochondrial electron C) carbon monoxide
transport chain? D) hydrogen
A) 10 E) oxygen
B) 24
25. How do many potent respiratory They bind to the
C) 12
poisons exert their effect? cytochrome
D) 30
A) They break down oxygen. oxidase catalytic
E) 20
B) They bind to electrons. site
20. How do mitochondria generate and by generating an C) They bind to the cytochrome
store the energy used to produce ionic oxidase catalytic site.
most of the ATP (electrochemical) D) They bind to oxygen.
made during aerobic respiration? gradient E) They denature the inner
A) by producing heat mitochondrial membrane.
B) by generating a heat gradient
26. You are trying to figure out an c
C) by generating an ionic
electron transport pathway including
(electrochemical) gradient
the following
D) by generating a Cl
electron transport molecules: B, K, T,
-
Q and X. You do so by employing
ion gradient
inhibitors for
E) by generating a Na
various steps in the process. When
+
you do, you get the following results:
ion gradient
Inhibitor Electron Transport
21. The direct formation of ATP by the ... Molecules Trapped in Reduced Form
transfer of a phosphate group from a Ticin Q & K
donor Digitin K
molecule to ADP is called ________. Estin T, K, Q & B
A) substrate-level phosphorylation Lucin Q, K & T
B) oxidative phosphorylation What is the order of the molecules
C) cyclic photophosphorylation (the pathway) in the electron
D) noncyclic photophosphorylation transport chain
E) indigenous phosphorylation suggested by the above data from
the most reduced to the least
22. What type of electron carrier has a ...
reduced molecule?
prosthetic group derived from vitamin
A) K —> T —> B —> Q —> X
B2?
B) K —> X —> B —> Q —> T
A) flavoproteins
C) K —> Q —> T —> B —> X
B) cytochromes
D) X —> B —> T —> Q —> K
C) copper atom containing carriers
E) T —> B —> K —> Q —> X
D) ubiquinone
E) iron-sulfur proteins
27. Pathways in which H
+ pathways and proton wires
ions can "hop" through a
channel by exchanging
themselves with
other protons present along
the pathway are called
___________.
A) proton-conduction
pathways
B) electrical wires
C) proton wires
D) proton conveyer belt
E) proton-conduction
pathways and proton wires
28. Electrochemical gradients
have both a(n) _________ and
a(n) __________ component.
A) concentration, acidic
B) acidic, electrical
C) concentration, basic
D) concentration, electrical
E) acidic, basic
29. Electrochemical gradients
have both a(n) _________ and
a(n) _________ component.
A) concentration, acidic
B) acidic, electrical
C) concentration, basic
D) chemical, voltage
E) acidic, basic
30. Why did DNP kill patients
who took the drug to help
them lose weight?
A) It caused the patients to
oxidize their fat stores in a
vain attempt to maintain
normal
ATP levels.
B) It blocked hemoglobin.
C) It caused an infection.
D) It caused total paralysis.
E) It prevented the patients
from breathing.
proton-conduction
concentration, electrical
32.
chemical, voltage
It caused the patients to
33.
oxidize their fat stores in a
vain attempt to maintain
normal
ATP levels
31. What is the purpose of They function as a source of
uncoupling proteins in heat production during
mammalian brown adipose exposure to cold
tissue? temperatures
A) They give the tissue its
color.
B) They help the tissue
expand and contract when
needed.
C) They function as a source
of heat production during
exposure to cold
temperatures.
D) They allow the production
of a larger number of ATPs
per glucose.
E) They allow muscles to
contract more efficiently
The F0 base of ATP synthase ...
serves as a(n) ______.
A) enzyme that synthesizes
ATP
B) enzyme that hydrolyzes
ATP
C) channel that conducts
protons from the
intermembrane space back to
the matrix
D) channel that conducts
protons from the matrix back
to the intermembrane space
E) proton pump
The energy released by decreases the binding
proton movement through affinity of the active site for
ATP synthase ___________. the ATP product
A) directly phosphorylates
ADP to ATP
B) increases the binding
affinity of the active site for
the ATP product
C) directly phosphorylates
ATP to ADP
D) decreases the binding
affinity of the active site for
the ATP product
E) directly phosphorylates
AMP to ATP1