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2. Glucose and galactose are epimers and they differ structurally in orientation of H and OH on:
a. C1 b. C3 c. C2 d. C5 e. C4
10. The reducing ability of a carbohydrate is due to the presence/or formation of:
a. A free carboxyl group b. A free hydroxyl group c. Enediol formation d. Presence of a 1-4 linkage
e. Formation of ring structure
22. Spermatozoa in seminal fluid utilises the following sugar for its metabolism:
a. Galactose b. Glucose c. Sucrose d. Fructose e. Mannose
8. A fatty acid which is not synthesised in human body and has to be supplied in the diet:
a. Palmitic acid b. Oleic acid c. Linoleic acid d. Stearic acid e. Valeric acid.
10. The triacyl glycerol present in plasma lipoproteins are hydrolysed by:
a. Lingual lipase b. Pancreatic lipase c. Co-lipase d. Lipoprotein lipase e. Adipokinetic lipase.
18. The maximum number of double bonds present in essential fatty acids is:
a. 1 b. 2 c. 3 d. 4 e. 5
19. Cerebrosides are composed of:
a. Sphingosine, fatty acids, glycerol, phosphoric acid b. Sphingosine, fatty acids galactose
c. Glycerol, fatty acids, galactose d. Glycerol, fatty acids, galactose, sphingol
e. Sphingosine, glucose, fatty acids, glycerol.
2. All PGs have a structure based on prostanoic acid which contains a cyclopentane ring and has carbon atoms:
a. 10 b. 15 c. 18 d. 20 e. 25
3. Regarding arachidonic acid the following statements are all true except:
a. Can be synthesised from linoleic acid. b. It is a 20 carbon fatty acid with five double bonds.
c. It is a precursor of PG-I2 d. It can form cyclic endoperoxide PG-H2
e. It is a precursor of Tx-A2
11. All prostaglandins have in common in addition to cyclopentane ring one double bond between positions:
a. C5 and C6 b. C7 and C8 c. C9 and C10 d. C11 and C12 e. C13 and C14
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4. All of the following are sulfur containing amino acids found in proteins except:
a. Cysteine b. Threonine c. Cystine d. Methionine e. Homocysteine
6. With the exception of glycine, all amino acids found inproteins are:
a. Optically inactive b. Dextrorotatory c. Of L-configuration d. Laevorotatory
e. Of D-configuration
7. In protein structure, the -helix and -pleated sheet are examples of:
a. Primary structure b. Secondary structure c. Tertiary structure d. Quaternary structure
e. Subunit structure
8. Glutathione is a:
a. Dipeptide b. Polypeptide c. Oligopeptide d. Tripeptide e. None of the above
19. Ninhydrin reaction gives a purple colour and evolves CO2 with:
a. Peptide bonds b. Histamine c. Egothioneine d. Asparagine e. Serotonin
5. Plasma proteins which contain more than 4 per cent hexosamine are designated as:
a. Microglobulins b. Cryoglobulins c. Mucoproteins d. Glycoproteins e. Orosomucoids
6. Plasma proteins which are precipitated best by 1/5th saturation of ammonium sulphate:
a. Albumin b. 2-globulins c. -globulins d. Euglobulins e. Fibrinogen
2. Immunoglobulin classes are differentiated from each other on the basis of their:
a. Electrophoretic mobility b. Molecular weight c. By their light chains d. By their heavy chains
e. By Sedimentation co-efficient
3. The serum antibody responsible for fighting gram +ve pyogenic bacteria is:
a. IgD b. IgE c. IgG d. IgA e. All of the above
10. In considering the properties of immunoglobulins, which of the following statement is true?
a. Half-life of IgG is shorter than IgA and IgM b. ‘L’-chains determine the class of immunoglobulins
c. Less than 50 per cent of total immunoglobulins is IgG
d. In respiratory tract secretions, the predominant immunoglobulin is IgA e. IgA can cross placental barrier
11. For differentiating malignant from benign paraproteinaemias the following can be useful:
a. Measurement of serum proteins
b. Measurement of cryoglobulins
c. Measurement of serum immunoglobulins
d. Detection of polyclonal light chains in urine
e. None of the above
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6. Which of the following statements about an enzyme exhibiting allosteric kinetics with cooperative interaction is false?
a. A plot of V-Vs (S) has a sigmoidal shape
b. An inhibitor may increase the apparent Km
c. Lineweaver-Burk plot is useful for determining Km and Vmax
d. Removal of allosteric inhibitor may result in hyperbolic V-Vs (S) plot
e. Small changes in (S) produce the largest change in V when (S) = Km
8. An enzyme that catalyses the coversion of an aldose sugar to a ketose sugar would be classified as one of the:
a. Transferases b. Isomerases c. Oxidoreductases d. Hydrolases
e. Lyases
9. In which of the following types of enzymes an inducer is not required?
a. Inhibited enzyme b. Cooperative enzyme
c. Allosteric enzyme d. Constitutive enzyme e. None of the above
10. In which of the following types of enzyme water may be added to a C=C double bond without breaking the bond?
a. Hydrolase b. Hydratase c. Hydroxylase d. Esterase
e. Oxygenase
1. All of the following electron carriers are components of the mitochondrial electron transport chain except:
a. FMN b. FAD c. NAD+ d. NADP+ e. Co-enzyme Q
3. Electrons from pyruvic acid enter the mintochondrial electron transport chain at:
a. Nadh – Q reductase
b. Coenzyme Q
c. QH2– cytochrome c-reductase
d. Cytochrome c oxidase
e. Between CoQ and cytochrome b
8. In oxidative phosphorylation the oxidation of one molecule NADPH produces how many ATPs?
a. Zero b. 2 c. 3 d. 4 e. 5
9. In oxidative phosphorylation, one molecule of reduced flavoprotein produces how many ATPs:
a. Zero b. 2 c. 3 d. 4 e. 5
13. The chemical energy required for the synthetic processes is provided by:
a. Phosphorylation of ATP b. Dephosphorylation of ATP c. Phosphorylation of ADP
d. Dephosphorylation of ADP e. All of the above processes
14. Which of the following vitamins of not a component of electron transport chain?
a. Nicotinamide b. Ubiquinone c. Biotin d. Riboflavin e. None of the above
3. In sickle-cell Hb the position 6 of glutamyl residue of - chain of normal adult Hb is replaced by:
a. Lysine b. Tyrosine c. Valine d. Leucine e. Glutamine
10. Sickle cell anaemia is the clinical manifestation of homozygous genes for an abnormal Hb molecule. The mutational event
responsible for mutation in the -chain is:
a. Deletion b. Insertion c. Point mutation d. Crossing over
e. Non-dysjunction
12. The incidence of salmonella infections is most often increased in patients with:
a. Sickle cell anaemia b. -chain thalassaemia c. G-6 PD deficiency of RB cells
d. Hereditary spherocytosis e. Hexokinase deficiency of RB cells
13. Which of the following statement is correct?
a. In Oxy-Hb formation Fe in haem is converted to ferric form
b. CO2 combines with haem to form carboxy-Hb
c. Co combines with NH2 group of Hb to form carbaminocompound
d. H2S combines with oxy-Hb to form sulfhaemoglobin
e. Fe in haem remains in ferrous form in methaemoglobin formation
17. The methylidene bridges of Fe porphyrin ring of haem molecule of Hb arises from:
a. The -carbon of succinyl-CoA
b. The carboxyl carbon of serine
c. The -carbon of serine
d. The -carbon of serine
e. The carbon from CO2
19. Cyanide is poisonous and lethal due to the fact, that it:
a. Inhibits myoglobin of muscle
b. Combines with Rb cells membrane
c. Forms a complex with Hb molecule
d. Inhibits cytochrome oxidase of electron transport chain
e. Damages the brain cells