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KAUSHAL BHATT

Syllabus overview for


GPAT/NIPER.
Pharmaceutics:
 Lachman – chapter 1 to 7 are important. Chapter 8, 11 – 22 are to be
done from this book. Tables on page number are important – 27,
37,44,98, 151,165,174,321,357
(only ingredients),416
(onlyingredients),419,434,453,463,467,508,514,515518,521,522,
551570 (names only), 621,631, 634, 642, 646 (tricky question
like most permeable can be asked), 648.
 Martin – if you read Subramanyam whole, then do chapter 1, and
last 2 chapters (biomaterials and delivery systems from it.)
 Brahmankar – whole book, read units of various parameters. CDDS.
Remember various release models.
 Cosmetics - remember only general things from B. M. Mitthal.
 R. M mehta – Posology, calculations are important.
 Cooper-gun – read method for sterilization of various injections given
at the end of
book.Containers, surgical instruments and sterilization at least see if u get
time.
 Extra – stability testing, ICH guidelines, drug approval process like
NDA, ANDA, ORANGE BOOK.
 Intellectual property rights (NIPER only).
 What is being studied in niper is also asked.(that leave to us)

 Gmp guidelines.

Pharmacology:

 Rang and dale remains the standard book for GPAT/NIPER. (do all
important tables from it.)
 K.D TRIPATHI – see heamatology, cancer, antibiotics, disinfectants and
vaccines from it.
 See adverse drug reactions from ROGER-WALKER book.
 Clical trials.
 Pharmacological classification from KDT only.

Medicinal chemistry:
 Wilson – read only following things:
KAUSHAL BHATT

 Structures of important drugs(s) and their starting material.(sm)

For Structures :

Dapsone, Isoniazid, Ethambutol, Pyrizinamide, Metronidazol, Methoxy Penicillin,


Chloroquine, Ampicilin, Chlorpromazine, Haloperidol, Diazepam. Glutethimide,
Phenobarbitone, Nikethamide, Isoprenaline, Ephedrine, Propranalol,
Neostigmine, Furosemide, Hydrochlorthiazide, Lignocaine, Procaine,
Diphenhydramine, Pethidine, Indomethacin, Phenylbutazone, Thyroxine,
Acetozolamide, Thiotepa, Cloxacillin, Nephazoline, Phentolamine, Streptomycin,
Penicillin, Nitrofurantoin, Thiobendazole, Digitoxin, Atropine, Cocaine,
Methotrexate, Trimethoprim, Clonidine, Phentoin, Papverine, Quinine,
Chlorthalidone, Hydralazine, Mepyramine, Promathazine, Cyclizine,
Cetrizine, Cyproheptadine, Triprolidine, Astemizole, Cimetidine, Ranitine,
Antazoline, Tripelennamine, Benzocaine, Ketamine, Thiopentone, Valproic Acid,
Carbamazepine, Methohexital, Amitryptiline, Testosterone, Progesterone,
Hydrocortisone, Diethylstilbesterol, Dienesterol, Ethacrynic Acid, Allopurinol,
Captopril, Proparanalol, Guanethidine, Dextropropoxyphene. Ibuprofen , Fentanyl,
Indomathacin, Prednsolone, Betamethasone, Triamicinolone, Cortisone, Estradiol,
Cholesterol, Stanozolol, Probenecid, Ketoconazole, Amphotericin, Nystatin,
Primaquin, Artemisin, Gentamicin,Neomycin, Erythromycin, Ampicilin,
Amoxicillin, Tranyl Cypromine, Chloramphenicol,
Metronidazole, Mebendazole, Thiabendazole, Cyclophophamide, Chlorambucil,
Cisplatin, Diloxanide Furoate, Trimethoprim, Mefloquine, Mafenide,
Amantidine, Zidovudine, Stavudine, Lamivudine, Foscarnet, Ganciclovir, Acyclovir,
Alprazolam, Triazolam, Diazepam, Buspirone, Promazine, Pargyline, Guanadrel,
Terazosin, Dopamine, Dobutamine, Noradrenaline, Atenolon, Pralidoxime,
Isoprenaline, Pyridostigmine, Tacrine, Papaverine, Naloxone, Naltrexone,
Morphine, Triamterene, Amiloride, Diltiazem, Verapamil, Nifedipine,
Amlodipine, Atropine, D- Tubocurarine, Succinyl Choline, Emetine,
Hydralazine, Reserpine, Vit. E, Tocopherols, Vit. A, Spiranolactone,
Caffeine, Codeine, Piperacillin, Ticarcillin, Idoxiuridine, Fluorouracil,
Metformin, Rosiglitazone, Glipizide, Gliburide, Busulfan, Mercaptopurine,
Melphalan,Methyl Dopa, Minoxidil, Sulindac, Flucortisone, Ciprofloxacin,
Gatifloxacin,Tamoxifen, Tolbutamide, Bupivacaine, Clomiphene, Diethyl
Carbamazepine, Undecylenic Acid,Flucytosine, Griseofulvin,
Terbinafine, Tolnaftate, Miconazole, Itraconazole, Lomefloxacin,Piperazine,
Ivermectin, Kanamycin, Gentamicin, Minocycline, Rolicycline, Clindamycin,
Vancomycin, Colistin, Polymixin, Bacitracin, Gramicidin, Mechlorethamine,
Ifosfamide, Procarbazine, Carboplatin, Hydroxyurea, Ketamine, Propofol,
Halothane,Primidone, Gabapentin, Theophylline, Theobromine, Amphetamine,
Sibutramine, Buproprion, Phenylephrine, Tolazoline, Phentolamine, Donepezil,
Edrophonium, Torasemide, Nitroglycerin, Digoxin, Enalapril, Losartan, Valsartan,
Clofibrate, Gemfibrozil, Fenofibrate, Nicotinic Acid, Probucol, Warfarin, Glimepiride,
KAUSHAL BHATT

Propyl Thiouracil, Methimazole, Clemastine, Loratidine, Famotidine,


Progesterone, Structure Of All Vitamins, Atovastatin(Lipitor), Simvastatin.

Starting Material:

Dapsone, Isoniazid, Etahmbutol, Pyrizinamide, Chloroquine,


Ampicilin,Chlorpromazine, Haloperidol, Diazepam.
Glutethimide, Phenobarbitone, Nikethamide, Isoprenaline,Ephedrine, Propranalol,
Neostigmeine, Furosemide, Hydrochlorthiazide, Lignocaine, Procaine,
Diphenhydramin, Pethidine, Indomethacin, Phenylbutazone,
Thyroxine, Acetozolamide,
Thiotepa, Cloxacillin, Nephazoline, Digitoxin, Atropine, Cocaine, Methotrexate,
Trimethoprim, Clonidine, Phentoin, Papverine, Quinine, Mepyramine,
Promathazine,Cyclizine, Cetrizine, Cyproheptadine, Triprolidine, Astemizole,
Cimetidine, Ranitine, Antazoline, Benzocaine, Ketamine, Valproic Acid,
Carbamazepine, Methohexital, Amitryptiline, Testosterone, Progesterone,
Hydrocortisone, Diethylstilbesterol, Dienesterol, Ethacrynic Acid, Allopurinol,
Captopril, Proparanalol, Guanethidine, Dextripropoxyphene. Ibuprofen, Indomathacin,
Prednisolone, Betamethasone,
Triamicinolone, Cortisone, Estradiol, Cholesterol, Stanozolol,
Chloramphenicol, , Diloxanide Furoate, Trimethoprim, Mefloquine, Amantidine,
Diazepam, Dopamine, Dobutamine, Noradrenaline, Atenolol, Pralidoxime,
Isoprenaline, Pyridostigmine, Diltiazem, Verapamil, Nifedipine, Amlodipine,
Atropine, D-Tubocurarine, Succinyl Choline, Emetine, Hydralazine, Clofibrate,
Gemfibrozil, Fenofibrate, Nicotinic Acid, Sulindac, Progesterone, Edrophonium,
Nephazoline (These Are Enough) –

important SAR related point:

E:g position responsible for acid instability of


erythromycin. No of isomers for particular
drug.
Active isomer. Group responsible for activity of drug.

Which class drug belongs (chemical class, not pharmacological. Pharmacological class
from K.D TRIPATHI only)

Steroid chapter is very important.


KAUSHAL BHATT

Iupac you can see of above drugs from Harkishan Singh book.just see the structure u
will notice how iupac is given..for some of above drugs IUPAC mIght be complex and
lengthy or not found just leave it.
 Bioisosterism.
 QSAR – From FOYE/SN PANDYA.
 COMPFA like softwares.(NIPER) – LEAVE TO US
 IUPAC from Harkishan Singh book only.

Pharmacognosy:

 Kokate remains the standard book.


 Whole book.
 B.s, c.c, synonym, use, adulterant, chemical test, substitute, structure (of
imp drugs)
 If there are less adulterants or less info about adulterants in Kokate
see Trease and Evans for further.
 Earlier chapters general introduction are important from Kokate.
 Trease-Kvans -see flavonoids and quality control chapter from it.
 Who guidelines – Kokate is good but with limited information. See other
book.
 Caretenoids – Agrawal is good book. Remember only no of double
bonds, structure, use.
 Biochemical pathways – remember starting points.
 Amino acids from which alkaloids are derived are to be remembered E:g
tropane alkaloids from ornithine.
 Microscopy of following drugs:
 Read Khandelwall book other then above microscopies full.

Organic chemistry :

 Read only name reactions: Hoffman rearrangement etc (Mehta
and Mehta or Morrison/Boyd)
 Stereochemistry from (M/M or M/M).
 Various
catalyst from M/M E:g
lindlar
catalyst,wilkinson
catalyst
 General concepts from – M/M
 Glossary of M/M
KAUSHAL BHATT

Inorganic chemistry:

 Bahl and Tuli only –thermodynamic and nuclear pharmacy chapters are
very important. Other chapters are also important.
 Chatwal – remember only common names of compounds and their use
and water for injection limits.

Microbiology :

 Only Kokare (whole book) is enough. For microbiological tests see


INAMDAR.
 Vaccines read from it and also ip.
 Something from Tortora (For Niper – we will say later).
 Diagnostic tests.

Biochemistry :

 Satyanarayan is enough:
Do chapters 1 to 7 and
metabolism chapters. Do all
important tables.
 Biochemical teats (from R.K. GOYAL - available in GUJARAT only
others students should see SATYANARAYAN AND KALE BOOK)
 Fermentation causing microorganism from inamdar.

Pharma analysis:

 MASS – SILVERSTEIN, KASTURE, RAVISHANKAR.


 N – RAVISHANKAR,KASTURE,KEMP. (NIPER – PAVIA)
 UV,IR – RAVISHANKAR, KASTURE, CHATWAL/YR SHARMA.
 AAS/FLAME PHOTOMETRY/FLUORIMETRY –
RAVISHANKAR,KASTURE.
 GRAVIMETRY/REDOX/ACID-
BASE/POALRIMETRY/POLAROGRAPHY/
CONDUCTOMETRY/AMPEROMETRY /ETC– RAVISHANKAR
KASTURE.
 CALCULATIONS - UNDERWOOD.
 DSC/DTA/TGA – MARTIN, REMINGTON,
 KARL-FISCHER/KJELDAHL/CAURIUS/DUMAS etc determination
methods - bahl and bahl or any other book.
 Assays- KASTURE OR RAVISHANKAR.
KAUSHAL BHATT

 See analysis part from /REMINGTON also.


 Circular dichromism.
 Chromatography – RAVISHANKAR/KASTURE.

Jurispudence

 Gk jani/ kuchekar.
 Read important years.
 D and c act
 Schedules
 Form numbers
 Members
 Place of various institutes.

Niper only
 Biostatistics general concepts
 Management/accountancy/partnership: use Gujarat board 11 or 12
standard books like – accountancy, secretial practice etc or what is
studied in NIPER.
 Noble prize winners recent.
 Pharma news recent
 General knowledge.
 Apptitude (Maths)
 Recent approved usfda druigs (do only approved in may/june/july –
upto niper exam date)
 Banks full forms and when they established.

 Pharmaceutical full forms.


 Name and location of important institutes.
 Any other useful information which we say at last time.
 The things which are being studied in niper are also
asked. Most of this we will include in postal /series until you read
above things.
 DON’T READ FOR NIPER BEFORE GPAT.

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