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Care and management of a stoma:

maintaining peristomal skin health


Anna Boyles and Sharon Hunt

Anatomy and physiology of the skin


ABSTRACT The skin is the largest organ in the human body, accounting
It is estimated that around one in 500 people in the UK are living with for up to approximately 16% of the total body weight of an
a stoma, with approximately 21 000 operations that result in stoma average adult, weighing twice as much as the brain (Tortora
formation being performed each year (Colostomy Association, 2016). These and Derrickson, 2009). On average, skin is 1-2 mm in depth,
people face a unique set of challenges in maintaining the integrity of their although it can vary in its thickness depending on its individual
peristomal skin. This article explores the normal structure and function of functions and particular area of the body; the eyelids are only
skin and how the care and management of a stoma presents challenges for 0.5 mm in depth, whereas the plantar region of the foot can
maintaining peristomal skin health. Particular focus is paid to the incidence be up to 4 mm (Brooker, 1998). According to Turkington
of skin problems for those living with a stoma, whether it is temporary and Dover (2007), the skin is compiled of thick outer layers,
or permanent, and the factors that contribute to skin breakdown in this a complex system of sweat glands sensitive to temperature
population. Wider factors such as the central role of the clinical nurse alteration and a strong layer of fatty tissue and sensitive cells,
specialist and the impact of product usage on positive outcomes and health which alert the body to pain, pressure, touch, irritation, heat
economics are also considered. and cold triggers, all residing just beneath the skin surface.
Key words: Anatomy and physiology  ■ Skin  ■ Stoma care  The skin contains an acid mantle, an invisible covering with
■ MARSI  ■ Skin breakdown  ■ Quality of life  ■ Outcomes
a pH range of 4 to 5.5. This provides the closed skin surface
with a protective barrier from outside influences, damage and

T
injury, particularly excessive moisture, bacteria and frictional
he skin is often referred to as the largest organ surfaces. The acid mantle aids the skin in the prevention of
of the body and performs a number of functions excessive fluid and electrolyte loss to maintain homeostasis
vital to the maintenance of homeostasis (Tortora (Tortora and Derrickson, 2009). When the acid mantle is
and Derrickson, 2009). The formation of a stoma ‘interrupted’ through either an increase of acidity or alkalinity,
and management of its output with appliances and the skin is vulnerable to epidermal stripping, infection and
accessories can prove to be a challenge to this equilibrium wound development (Bateman and Roberts, 2013).
for a variety of reasons. The Colostomy Association (2016) Skin types vary from individual to individual and can be
estimates that there are currently 120 000 people living with segregated generally into four types: dry, oily, normal and
a stoma in the UK, with around 21 000 operations performed sensitive, which can affect how the skin responds to both internal
annually for a wide range of bowel and urinary diseases and and external stimuli, nutrients and moisture levels (White, 2014).
disorders, meaning around 1 in 500 people face this challenge
on a daily basis. Stratum corneum
This article explores the normal structure and functions The skin is comprised of three main layers: the epidermis, the
of the skin, the factors that can influence the preservation of dermis and subcutaneous tissue (Kanitakis, 2002) whose overall
good skin health, the perspective that stoma care has on the function is to absorb, excrete, protect, secrete, thermoregulate,
importance of maintaining good skin integrity and the burden pigment produce, perceive senses and provide a safe environment
that the care and management of a stoma place on patients through immunological responses (Hampton and Stephen-
and those who care for them. Haynes, 2005).
The uppermost layer, the epidermis, consists of 90% stratified
squamous epithelium cells known as keratinocytes, whose
function is to synthesise keratin, a protein with a strong protective
Anna Boyles, Nurse Specialist, Stoma Care, King’s College function. It also contains 8% melanocytes, responsible for the
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Hospital NHS Foundation Trust production of the pigment melanin, and 2% langerhans and
Sharon Hunt, Lead Advanced Nurse Practitioner, Wellway Medical merkel cells, which allow immune responses and touch sensation
Group, Independent Specialist Wound Care respectively (Tortora and Derrickson, 2009). Ceramide is the
Accepted for publication: August 2016 main component of the stratum corneum of the epidermis layer,
together with cholesterol and saturated fatty acids. Ceramide

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involved in include: forming a ‘bricks and mortar’ model
Sensory nerve ending comprising the corneocytes, as the ‘bricks’ embedded in lipids
for touch Cell loss from
Hair shaft stratum corneum with ceramides, or the ‘mortar (Gray et al, 2011;Voegeli, 2012);
structuring and maintaining water permeability barriers within
Stratum corneum
Sweat pore (horny layer) the skin (Feingold, 2007), and forming waterproofing of the skin.
Stratum lucidum This outer layer is dependent on the next layer, the dermis, for
Stratum granulosum its supply of oxygenation, metabolic delivery and waste removal,
Stratum spinosum
because of its avascular structure. The middle layer, called the
Epidermis Stratum basale
Basement membrane zone dermis, is fundamentally built up of an integrated system of
Sebaceous gland
fibrous, filamentous and amorphous connective tissue inclusive
Blood vessels
of a fibrillary protein, known as collagen. The dermis provides
Dermis the bulk of the skin ensuring its elasticity, pliability and tensile
Papilla of hair strength (Kanitakis, 2002). It is in this layer where lymph vessels,
nerve endings, hair follicles and glands which are responsible
Hair follicle for exchanging nutrients between the dermis and epidermis
are found. There are up to 4 million sweat glands containing
Lymph vessels
hair follicles separated into two types, eccrine and apocrine,
Sweat duct Subcutis which are distinguished by their differing structures, locations and
(hypodermis)
Sweat gland
actual secretion. Eccrine glands allow thermoregulation through
Arrector pili muscle
evaporation to the skin surface ensuring temperature control and
Peter Lamb

Pacinian corpuscle
Nerve fibre skin moisture, whereas apocrine glands, which are activated by
hormones, produce what is commonly known as body odour,
Figure 1. Skin structure
when the secreted sweat metabolises with skin flora (Casey, 2002).
Table 1. Medications: cutaneous side effects and their causes In the final layer, the subcutaneous, fat cells or lipocytes are
separated by fibrous septa made up from large blood vessels and
Medication Cutaneous side effect Cause
collagen. Considered an endocrine organ, subcutaneous fatty
Steroids Bruising Act non-selectively so tissue provides the body with buoyancy, insulation and acts as a
Skin thinning impair healthy anabolic store for energy. It also provides protection and attachment to
processes that build up
Delayed healing underlying bone and muscle tissue (James et al, 2006).
organs and tissues
Fragile skin The skin requires regular maintenance to keep it at its
optimum functioning capacity (cleaning appropriately,
Anti-coagulants Bruising Inhibition of blood clotting
protection from the harmful sun rays, oxygenation through
Prolonged bleeding
physical exercise and a mixed varied healthy diet in rich
Chemotherapy Rash Act non-selectively so nutrients, alongside adequate fluid intake). These key aspects
Dry skin target rapidly dividing cells of skin care become more important as the body ages (National
Delayed healing Institute of Arthritis and Musculoskeletal and Skin Diseases
Increased bleeding from (NIH), 2016).
the stoma surface When skin is damaged owing to injury, infection, friction,
Pruritis excessive moisture, trauma, or dehydration, a system of
biological changes come into action. These are correlated
Nicorandil Ulceration Not understood
into set phases: haemostasis, inflammation, proliferation and
maturation (Collier, 2002).
creates a water-impermeable, protective organ to prevent Haemostasis is the response which starts immediately after
excessive water loss owing to evaporation, as well as a barrier skin injury; it is achieved by a combination of vasoconstriction
against the entry of microorganisms (Hill and Wertz, 2009). to conserve blood loss and the release of clotting factors, with the
Trans epidermal water loss (TEWL) relates to the amount clot acting as a bacterial barrier and a framework for migrating
of water that transfers from within the body to the external cells (Benbow, 2005).The clotting cascade is initiated and a mesh is
environment through the epidermis layer; for example, in formed trapping blood cells to start the next phase of inflammation.
perspiration (Elias, 2005). Gray et al (2011) suggested that Inflammation occurs because of the extensive vasodilation
TEWL increases when skin dysfunction—such as stripping presenting heat, swelling, erythema and often discomfort to the
trauma, infection, eczema and psoriasis—occurs. site of injury, where increased neutrophils appear to cleanse the
The TEWL process is significantly reliant on ceramides, area of bacteria and devitalised tissue, a phase that occurs over
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which play an essential role in minimising water loss, ensuring a 24–48 hour period (Collier, 2002). Wound exudate, which is
the moisture level of the stratum corneum is optimised and produced at this phase, contains substances that are vital for the
maintaining skin health and protection (Coderch et al, 2003). tissue to progress to full healing, such as neutrophils, macrophages,
Other important aspects related to fluids and management lymphocytes, proteases and essential growth factors. When
within the biological system of the body that ceramides are contained, wound exudate is vital for wound healing; however,

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SKIN HEALTH

when in excess and not managed appropriately, tissues may become


macerated, damaged and healing can stall (Timmons, 2006).
Proliferation or granulation, which occurs around day 3 to
14 (Casey, 2002), is where healthy vascular rich tissue is laid
down within the wound bed, allowing wound contraction and
epithelial cells to migrate, to eventually form closure of the wound.
Epithelial cells form within hair follicles, sebaceous and sweat
glands, which are essential to keeping the new tissue protected,
moist and at optimal functioning states (Timmons, 2006).
The onset of maturation varies extensively depending on
the wound size, closing by primary or secondary intention,
comorbidities and overall skin health. During this phase, the
wound is strengthened and the scar will change in colour
significantly. Fully healed and formed scar tissue is relatively
avascular, containing no hair or sweat glands, and can take from
1 to 2 years to achieve (James et al, 2006).

How the stoma and device can contribute to


peristomal skin breakdown
The incidence of peristomal skin problems is widely described in
the literature. Richbourg et al (2007) reported skin breakdown
as the most common complication in their post discharge study
group and put incidence at 74–83%, while other studies point
towards 21–70% of ostomists (those living with a stoma), dealing Figure 1. Mild peristomal excoriation
with complications or a problematic stoma (Leenen and Kuypers,
1989; Bass et al, 1997; Shellito, 1998; Cottam and Richards, 2006).
Other groups have reported that 6-70% of patients experience
peristomal skin irritation or breakdown (Nugent et al, 1999;
Ratliff et al, 2005) and Lyon (2013) postulated that upwards of
10% of peristomal rashes are unable to be attributed to primary
disease, allergy or infection, and are more likely to be secondary to
a low-grade irritant process related to the occlusion of the stoma
appliance. Examples of mild, moderate and severe peristomal
excoriation are illustrated in Figures 1–3.
A study by Herlufsen et al (2006) found that the majority
of problems are experienced by patients with an ileostomy, of
whom 57% have peristomal skin problems. Of those with an
ileal conduit 48% experience issues, while 35% of colostomists
have problems. These findings could well be attributed to the
amount and type of output being contained, but even taking
this into account, it is clear that for every 10 colostomists
who are still using the vast majority of their gut complement
and will therefore have a more conventional stool, at least 3
will still experience issues with their peristomal skin. Woo
et al (2009) offered that of those ostomists diagnosed with a
peristomal skin disorder, 77% could be related to contact with
their stoma output. Figure 2. Moderate peristomal excoriation
All stomas are created by exteriorising part of the bowel
through the abdominal wall to the surface, where it is everted normal length of gut is still in use. The ileocaecal valve is still
and sutured into place. Colostomies sit relatively flush to the in situ acting as a brake between small and large bowel, and the
skin and ideally should spout 10–15 mm (Cottam and Richards, vast majority of absorption has happened during transit.As such,
2005). Ileostomies should protrude slightly more, with a spout the enzymes and salts that aid digestion have been neutralised
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of 2–2.5 cm (Hall et al, 1995), and ileal conduits should be making the stool passed likely to be soft to semi-formed and
similar to an ileostomy spouting 1.5–2.5 cm (Fillingham, 2005). less irritant.A colostomy is also likely to have periods of relative
The need for this type of length in a stoma spout is directly inactivity over the course of the day and tends to function
related to the consistency, amount and content of its output. more in keeping with what patients have been used to as their
As a colostomy is formed from part of the colon, most of the usual bowel habit.

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The risk of medical adhesive
related skin injury
Adhesives used in stoma appliances and accessories play a part in
maintaining skin integrity. However, there is a potential for the
adhesives themselves to cause skin problems. Medical adhesive
related skin injury (MARSI) is a mechanism of skin injury that
occurs when the skin to adhesive attachment is stronger than the
skin cell to skin cell attachment. This causes a cohesive failure
within the structure of the skin that leads the epidermal layers
to part or separates the epidermis from the dermis (McNichol,
2013). This type of injury may manifest itself in a number of
ways; from the removal of layers of the stratum corneum (so-
called skin stripping) and maceration from trapping moisture
next to the skin for prolonged periods, to tension injuries such
as blisters or tears. While there may not be any visible trauma,
there is a cumulative removal of epidermal cells that over time
will result in a compromise to the skin barrier function, that will
Figure 3. Severe peristomal excoriation
in turn result in the mounting of an inflammatory and wound
healing response.
The output from an ileostomy is looser, as stool will not There are a number of factors that lead to the mechanism of
have passed through the colon where the majority of water injury.These include the energy required to remove the adhesive,
is reabsorbed, giving the stool its form and consistency. The the composition of the adhesive and the occlusiveness of the
volume of output passed from an ileostomy increases inversely adhesive.The moisture that gets trapped underneath an occlusive
to the length of remaining small bowel in continuity, but a dressing leads to maceration and irritation of the skin, which
normal output for a terminal ileostomy is considered to be increases the risk of mechanical trauma. Hydrocolloid adhesives
600–800 ml in 24 hours (Black, 1997). Anecdotally, many trap moisture over time, meaning the skin becomes macerated
patients manage without problems with an output of around and more permeable, thereby increasing its susceptibility to
1000 ml in 24 hours; anything above this can be considered friction and irritants. However, it has been argued that the ability
a high output, putting patients at risk of dehydration and of hydrocolloid barriers to absorb excess moisture can reduce
electrolyte imbalance (Nightingale and Woodward, 2005). Small these unfavourable side effects when compared to other occlusive
bowel content from an ileostomy still contains the acids and salts barriers (Zaih and Maibach, 2002).
secreted higher in the gut to be used for chemical digestion, McNichol et al (2013) postulated that MARSI constitutes
which gives it a more corrosive nature when it comes into ‘a significant negative impact on patient safety.’ Aside from the
contact with peristomal skin. obvious physiological effect of skin damage leaving wounds that
An ileal conduit will pass urine at a steady rate as the storage require healing, associated pain, an increased risk of infection and
provided by the bladder has been lost. An average volume further skin breakdown, there are also psychological ramifications.
may be around 1500 ml per day (Burch, 2006), although this Patients with skin damage can suffer compromise to their
is variable on the level of hydration and renal function of the quality of life through interference with their normal physical
individual. Exposure of the peristomal skin to urine will in itself activities.This can lead to social isolation, increased anxiety and
increase risk of irritation, but there is an added consideration even depression (Herlufsen et al, 2006; Woo et al, 2009; Boyles,
of maceration where the appliance holds the moisture next 2010a; McMullen et al, 2011; Salvadalena, 2016). Add to this the
to the skin for long periods, thus increasing permeability and financial implications of treating this type of injury-not only in
the risk of breakdown. terms of supplies but also service provision and time-then the
In practice, higher stomal outputs provide a greater multifaceted negative effects of this type of injury will soon mount.
challenge to containment and skin protection. Looser output
in larger volume will find the smallest weakness or gap in Intrinsic factors contributing to peristomal
the hydrocolloid barrier, meaning the skin will be exposed skin breakdown
to the stool and make the appliance more likely to leak. A There are various intrinsic factors that can have an influence
more corrosive output will also contribute to the corrosion on how skin behaves when exposed to the various stressors
of the hydrocolloid adhesive, known colloquially as ‘melt’, brought about by both the stoma and appliance.
which also leads to a loss of the skin barrier next to the stoma As skin ages, it becomes more susceptible to damage and
and an increased risk of subsequent skin problems. In the breakdown as a result of the following factors:
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author’s (A.B.) practice, patients who have a higher output ■■ Loss of the dermal matrix
will often need to change their appliance more regularly or ■■ Loss of subcutaneous tissue
use accessories, such as seals or skin barrier films, to protect ■■ Epidermal thinning
the peristomal skin and reduce the incidence of irritation ■■ Reduction of the cohesion between dermal and
and breakdown. epidermal layers

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SKIN HEALTH

■■ Reduced vascularity within the group who had undergone surgery for intractable
■■ Reduced elasticity incontinence reported an increase in sexual activity.The concept
■■ Reduced tensile strength of sexual function covers both paradigms under consideration
■■ Less moisture (Lober and Fenske, 1991; Cutting, 2008; here, and it is worthy of note that while physical problems may
Wysocki, 2012). stop some patients from fulfilling their normal sexual function,
Ethnicity is also being shown to have an effect on how other more subjective issues such as self-perception and body
skin is affected by exposure to adhesives. Differences in confidence also exert their influence.
percutaneous absorption rates and the level of stratum corneum The incidence of stomal complications holds a great influence
lipid (ceramide) content and tensile mechanical properties of over patients’ objective functioning. Nordström and Nyman
the dermis (skin rigidity) across skin tones all play a part. This (1991) found that higher incidences of complications and
concept is still emerging, but there is some evidence to show practical problems with stoma care made patients more likely
that darker skin tones tend to have a higher degree of rigidity to stop work and restrict social activity.This was consistent with
than lighter skin tones that may make it more prone to injury the group studies by Pitmann et al (2009), who found that the
(Evans et al, 2012), while ceramide levels have been found to severity of complications, such as sore skin and appliance leaks,
be higher in Asian skin types and lowest in darker skin types had a direct correlation with the severity of the impact which in
(Richards et al, 2003). turn led to problems with adjustment postoperatively. Gooszen
Additional intrinsic factors can also increase the risk of skin et al (2000) also found this within their study group.They also
damage.These range from comorbidities, such as diabetes, renal revealed that the link between the incidence of complications
failure, immunosuppression, hypertension and peristomal varices, and degree of isolation was stronger where people had a pre-
to other conditions such as psoriasis, eczema, malnutrition and existing level of social constraint. Of these participants 17%
dehydration. Extrinsic factors including dry skin, maceration, were unable to achieve a level of self-care, meaning they had
radiotherapy, friction from the appliance or clothing, as well as lost their independence and were reliant on others for help. It is
certain medications, also have an effect on the skin that increases worth noting that this study group were living with a temporary
the risk of MARSI. stoma. Other studies of similar groups showed uncertainty and
worries over disclosure, coping strategies, looking for practical
Quality of life and wellbeing solutions to complications and difficulties with exercise, sleep,
There are a variety of reasons why a stoma may be formed. sex, pouch management and clothing, (Neuman et al, 2011;
The raising of a stoma will always be part of a wider disease Danielsen et al, 2013). Many patients report a good quality of
or disorder process, which means that people will arrive at life despite stoma related difficulties (Neuman et al, 2012), but
that point from a range of physical and psychological places. there seem to be differences between how these patients and
Regardless of the reason for stoma formation, it will always have those living with a permanent stoma perceive their quality of life.
a multifaceted impact on how people live their lives. For those living with a permanent stoma, Feddern at al (2015)
Quality of life is generally concerned with two aspects of found there was little or no impact on how patients perceived
information: functional status and how patients judge their their quality of life. Nair et al (2014) saw a dip at 2 weeks
health to affect their quality of life (Muldoon et al, 1998). postoperatively that returned to preoperative levels by 3 months,
Relating health to these physical and mental parameters allows and Chambers et al (2012) found a response shift towards good
the assessment of two factors: objective functioning (the ability quality of life. Campos-Lobarto et al (2011) compared those
to perform tasks) and subjective wellbeing (how an individual undergoing abdominoperineal excision (APER) and formation
evaluates their state of health). of permanent colostomy with those undergoing low anterior
The concept of objective functioning can relate to a range resection. The APER group had a lower start point at time of
of physical tasks, from the ability to walk a certain distance surgery; at 6 months, the differences between the groups was
to the ability to resume a normal sex life, while it may also not significant and had disappeared by 36 months.
encompass an individual’s ability to perform cognitive and It is easy to see that living with a stoma has some inevitable
social tasks. In terms of stoma care, it can be more related to effects on how people view themselves and live their lives.
achieving a level of confidence to resume normal routines, Complications such as sore skin appear to have a direct negative
such as work and social activities, as well as being physically impact on patient outcomes in this area, but there are wider
capable of going back to a job that requires a certain level issues that are worthy of note. In terms of money, the cost
of physical activity. In a study by Nugent et al (1999) 8% of of prescribed stoma care products in England for 2015 was
colostomists and 11% of ileostomists changed their job as a £280 million, of which £74 million was on accessories. To
result of surgery, but within the same group, 50% of respondents give this figure some context, the total cost of dispensed
reported that their stoma had little or no effect on their ability prescriptions in that year was £9.27 billion (Health and Social
to find work. In terms of sexual function within the group, Care Information Centre, 2016).As this cost is purely related to
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45% of ileostomists and 43% of the colostomists experienced the materials needed for stoma care, these figures do not take
problems after surgery. Nordstrom and Nyman (1991) reported into account any extra costs that treating complications may
that 90% of male urostomists experienced impotence, while incur.These may include additional medications or treatments,
the female participants reported little or no sexual activity referral on to other specialities, such as dermatology and,
after surgery. However, it is worth noting that those patients importantly, nursing time and resources needed to assess and

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failure, the embarrassment of leaks and the self-assurance in
KEY POINTS their products and technique they need to take their normal
■■ The trans epidermal water loss (TEWL) process is significantly reliant on place in the world.  BJN
ceramides, which play an essential role in minimising water loss
■■ Ceramides ensure the moisture level of the stratum corneum is optimised Declaration of interest: this article was supported by Hollister
and maintain skin health and protection
Acknowledgements: the authors thank Edwin Chamanga, Tissue
■■ A stoma will always have a multifaceted impact on how people live their
viability service lead, Hounslow and Richmond Community Healthcare
lives
NHS Trust, for his help with the preparation of the manuscript
■■ Intact peristomal skin is the cornerstone to promoting positive outcomes
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CPD reflective questions


■■ What would be your priorities in caring for a patient with a stoma? Have these changed as a result of reading this
article?
■■ How can you begin to address the psychological impact that can follow on from experiencing practical problems with
stoma management?
■■ Do you feel that your knowledge has improved in regards to skin anatomy and physiology since reading this article?
Has this knowledge increased your understanding of peristomal skin management principles?

Helping nurses treat common skin conditions


Dermatology Differential Diagno

About the book


Skin problems are one of the
most common reasons for
people to seek help from a nurse
or GP in general practice. This
handy reference guide is the

This practical and user-friendly book is made up of articles from a popular series in Practice
essential collection of common
dermatological cases encountere
d in everyday practice with concise
content on the aetiology, diagnosis,
management and prevention
so that healthcare practitione
rs can effectively treat their patients.

Nursing and covers: the aetiology, diagnosis, management and prevention of most common Importantly, this book also examines
patient care, with considerat
ion for how
other issues that impact
factors impact patients and treatment social and psychological
of skin conditions.

dermatological cases; social and psychological factors and their impact on patients and This book comprises updated
highly popular series published
articles from a long running and
in the Practice Nursing journal
the differential diagnosis of dermatolo on

treatment of skin conditions.


gical conditions. It has been
highly illustrated with colour
pictures provided throughout
*Low cost for landlines and mobiles

diagnosis. The chapters have to aid


been presented in a user-friend
format making this a highly practical ly
text for nurses and GPs.
sis

Highly illustrated, with colour pictures throughout, helps to aid diagnosis. Each chapter is About the author
Dr Jean Watkins is a retired GP

Dermatology
and remains an active member
Practice Nursing Editorial Board of the

presented in a user-friendly format making this a highly practical text for nurses and GPs.
and, in April 2004, was awarded
Fellowship of the Royal College a
of General Practitioners.

ISBN-13: 978-1-85642-401-1; 297 x 210 mm; paperback; 200 pages; publication 2010; £29.99 Differential
© 2016 MA Healthcare Ltd

Diagnosis
Jean Watkins

ISBN 1-85642-401-4
Jean Watkins
Order your copies by visiting or call our Hotline 9 781856 424011

www.quaybooks.co.uk +44 (0) 333 800 1900*


www.quaybooks.co.uk

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1

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