Professional Documents
Culture Documents
T
injury, particularly excessive moisture, bacteria and frictional
he skin is often referred to as the largest organ surfaces. The acid mantle aids the skin in the prevention of
of the body and performs a number of functions excessive fluid and electrolyte loss to maintain homeostasis
vital to the maintenance of homeostasis (Tortora (Tortora and Derrickson, 2009). When the acid mantle is
and Derrickson, 2009). The formation of a stoma ‘interrupted’ through either an increase of acidity or alkalinity,
and management of its output with appliances and the skin is vulnerable to epidermal stripping, infection and
accessories can prove to be a challenge to this equilibrium wound development (Bateman and Roberts, 2013).
for a variety of reasons. The Colostomy Association (2016) Skin types vary from individual to individual and can be
estimates that there are currently 120 000 people living with segregated generally into four types: dry, oily, normal and
a stoma in the UK, with around 21 000 operations performed sensitive, which can affect how the skin responds to both internal
annually for a wide range of bowel and urinary diseases and and external stimuli, nutrients and moisture levels (White, 2014).
disorders, meaning around 1 in 500 people face this challenge
on a daily basis. Stratum corneum
This article explores the normal structure and functions The skin is comprised of three main layers: the epidermis, the
of the skin, the factors that can influence the preservation of dermis and subcutaneous tissue (Kanitakis, 2002) whose overall
good skin health, the perspective that stoma care has on the function is to absorb, excrete, protect, secrete, thermoregulate,
importance of maintaining good skin integrity and the burden pigment produce, perceive senses and provide a safe environment
that the care and management of a stoma place on patients through immunological responses (Hampton and Stephen-
and those who care for them. Haynes, 2005).
The uppermost layer, the epidermis, consists of 90% stratified
squamous epithelium cells known as keratinocytes, whose
function is to synthesise keratin, a protein with a strong protective
Anna Boyles, Nurse Specialist, Stoma Care, King’s College function. It also contains 8% melanocytes, responsible for the
© 2016 MA Healthcare Ltd
Hospital NHS Foundation Trust production of the pigment melanin, and 2% langerhans and
Sharon Hunt, Lead Advanced Nurse Practitioner, Wellway Medical merkel cells, which allow immune responses and touch sensation
Group, Independent Specialist Wound Care respectively (Tortora and Derrickson, 2009). Ceramide is the
Accepted for publication: August 2016 main component of the stratum corneum of the epidermis layer,
together with cholesterol and saturated fatty acids. Ceramide
Pacinian corpuscle
Nerve fibre skin moisture, whereas apocrine glands, which are activated by
hormones, produce what is commonly known as body odour,
Figure 1. Skin structure
when the secreted sweat metabolises with skin flora (Casey, 2002).
Table 1. Medications: cutaneous side effects and their causes In the final layer, the subcutaneous, fat cells or lipocytes are
separated by fibrous septa made up from large blood vessels and
Medication Cutaneous side effect Cause
collagen. Considered an endocrine organ, subcutaneous fatty
Steroids Bruising Act non-selectively so tissue provides the body with buoyancy, insulation and acts as a
Skin thinning impair healthy anabolic store for energy. It also provides protection and attachment to
processes that build up
Delayed healing underlying bone and muscle tissue (James et al, 2006).
organs and tissues
Fragile skin The skin requires regular maintenance to keep it at its
optimum functioning capacity (cleaning appropriately,
Anti-coagulants Bruising Inhibition of blood clotting
protection from the harmful sun rays, oxygenation through
Prolonged bleeding
physical exercise and a mixed varied healthy diet in rich
Chemotherapy Rash Act non-selectively so nutrients, alongside adequate fluid intake). These key aspects
Dry skin target rapidly dividing cells of skin care become more important as the body ages (National
Delayed healing Institute of Arthritis and Musculoskeletal and Skin Diseases
Increased bleeding from (NIH), 2016).
the stoma surface When skin is damaged owing to injury, infection, friction,
Pruritis excessive moisture, trauma, or dehydration, a system of
biological changes come into action. These are correlated
Nicorandil Ulceration Not understood
into set phases: haemostasis, inflammation, proliferation and
maturation (Collier, 2002).
creates a water-impermeable, protective organ to prevent Haemostasis is the response which starts immediately after
excessive water loss owing to evaporation, as well as a barrier skin injury; it is achieved by a combination of vasoconstriction
against the entry of microorganisms (Hill and Wertz, 2009). to conserve blood loss and the release of clotting factors, with the
Trans epidermal water loss (TEWL) relates to the amount clot acting as a bacterial barrier and a framework for migrating
of water that transfers from within the body to the external cells (Benbow, 2005).The clotting cascade is initiated and a mesh is
environment through the epidermis layer; for example, in formed trapping blood cells to start the next phase of inflammation.
perspiration (Elias, 2005). Gray et al (2011) suggested that Inflammation occurs because of the extensive vasodilation
TEWL increases when skin dysfunction—such as stripping presenting heat, swelling, erythema and often discomfort to the
trauma, infection, eczema and psoriasis—occurs. site of injury, where increased neutrophils appear to cleanse the
The TEWL process is significantly reliant on ceramides, area of bacteria and devitalised tissue, a phase that occurs over
© 2016 MA Healthcare Ltd
which play an essential role in minimising water loss, ensuring a 24–48 hour period (Collier, 2002). Wound exudate, which is
the moisture level of the stratum corneum is optimised and produced at this phase, contains substances that are vital for the
maintaining skin health and protection (Coderch et al, 2003). tissue to progress to full healing, such as neutrophils, macrophages,
Other important aspects related to fluids and management lymphocytes, proteases and essential growth factors. When
within the biological system of the body that ceramides are contained, wound exudate is vital for wound healing; however,
of 2–2.5 cm (Hall et al, 1995), and ileal conduits should be making the stool passed likely to be soft to semi-formed and
similar to an ileostomy spouting 1.5–2.5 cm (Fillingham, 2005). less irritant.A colostomy is also likely to have periods of relative
The need for this type of length in a stoma spout is directly inactivity over the course of the day and tends to function
related to the consistency, amount and content of its output. more in keeping with what patients have been used to as their
As a colostomy is formed from part of the colon, most of the usual bowel habit.
author’s (A.B.) practice, patients who have a higher output ■■ Loss of the dermal matrix
will often need to change their appliance more regularly or ■■ Loss of subcutaneous tissue
use accessories, such as seals or skin barrier films, to protect ■■ Epidermal thinning
the peristomal skin and reduce the incidence of irritation ■■ Reduction of the cohesion between dermal and
and breakdown. epidermal layers
■■ Reduced vascularity within the group who had undergone surgery for intractable
■■ Reduced elasticity incontinence reported an increase in sexual activity.The concept
■■ Reduced tensile strength of sexual function covers both paradigms under consideration
■■ Less moisture (Lober and Fenske, 1991; Cutting, 2008; here, and it is worthy of note that while physical problems may
Wysocki, 2012). stop some patients from fulfilling their normal sexual function,
Ethnicity is also being shown to have an effect on how other more subjective issues such as self-perception and body
skin is affected by exposure to adhesives. Differences in confidence also exert their influence.
percutaneous absorption rates and the level of stratum corneum The incidence of stomal complications holds a great influence
lipid (ceramide) content and tensile mechanical properties of over patients’ objective functioning. Nordström and Nyman
the dermis (skin rigidity) across skin tones all play a part. This (1991) found that higher incidences of complications and
concept is still emerging, but there is some evidence to show practical problems with stoma care made patients more likely
that darker skin tones tend to have a higher degree of rigidity to stop work and restrict social activity.This was consistent with
than lighter skin tones that may make it more prone to injury the group studies by Pitmann et al (2009), who found that the
(Evans et al, 2012), while ceramide levels have been found to severity of complications, such as sore skin and appliance leaks,
be higher in Asian skin types and lowest in darker skin types had a direct correlation with the severity of the impact which in
(Richards et al, 2003). turn led to problems with adjustment postoperatively. Gooszen
Additional intrinsic factors can also increase the risk of skin et al (2000) also found this within their study group.They also
damage.These range from comorbidities, such as diabetes, renal revealed that the link between the incidence of complications
failure, immunosuppression, hypertension and peristomal varices, and degree of isolation was stronger where people had a pre-
to other conditions such as psoriasis, eczema, malnutrition and existing level of social constraint. Of these participants 17%
dehydration. Extrinsic factors including dry skin, maceration, were unable to achieve a level of self-care, meaning they had
radiotherapy, friction from the appliance or clothing, as well as lost their independence and were reliant on others for help. It is
certain medications, also have an effect on the skin that increases worth noting that this study group were living with a temporary
the risk of MARSI. stoma. Other studies of similar groups showed uncertainty and
worries over disclosure, coping strategies, looking for practical
Quality of life and wellbeing solutions to complications and difficulties with exercise, sleep,
There are a variety of reasons why a stoma may be formed. sex, pouch management and clothing, (Neuman et al, 2011;
The raising of a stoma will always be part of a wider disease Danielsen et al, 2013). Many patients report a good quality of
or disorder process, which means that people will arrive at life despite stoma related difficulties (Neuman et al, 2012), but
that point from a range of physical and psychological places. there seem to be differences between how these patients and
Regardless of the reason for stoma formation, it will always have those living with a permanent stoma perceive their quality of life.
a multifaceted impact on how people live their lives. For those living with a permanent stoma, Feddern at al (2015)
Quality of life is generally concerned with two aspects of found there was little or no impact on how patients perceived
information: functional status and how patients judge their their quality of life. Nair et al (2014) saw a dip at 2 weeks
health to affect their quality of life (Muldoon et al, 1998). postoperatively that returned to preoperative levels by 3 months,
Relating health to these physical and mental parameters allows and Chambers et al (2012) found a response shift towards good
the assessment of two factors: objective functioning (the ability quality of life. Campos-Lobarto et al (2011) compared those
to perform tasks) and subjective wellbeing (how an individual undergoing abdominoperineal excision (APER) and formation
evaluates their state of health). of permanent colostomy with those undergoing low anterior
The concept of objective functioning can relate to a range resection. The APER group had a lower start point at time of
of physical tasks, from the ability to walk a certain distance surgery; at 6 months, the differences between the groups was
to the ability to resume a normal sex life, while it may also not significant and had disappeared by 36 months.
encompass an individual’s ability to perform cognitive and It is easy to see that living with a stoma has some inevitable
social tasks. In terms of stoma care, it can be more related to effects on how people view themselves and live their lives.
achieving a level of confidence to resume normal routines, Complications such as sore skin appear to have a direct negative
such as work and social activities, as well as being physically impact on patient outcomes in this area, but there are wider
capable of going back to a job that requires a certain level issues that are worthy of note. In terms of money, the cost
of physical activity. In a study by Nugent et al (1999) 8% of of prescribed stoma care products in England for 2015 was
colostomists and 11% of ileostomists changed their job as a £280 million, of which £74 million was on accessories. To
result of surgery, but within the same group, 50% of respondents give this figure some context, the total cost of dispensed
reported that their stoma had little or no effect on their ability prescriptions in that year was £9.27 billion (Health and Social
to find work. In terms of sexual function within the group, Care Information Centre, 2016).As this cost is purely related to
© 2016 MA Healthcare Ltd
45% of ileostomists and 43% of the colostomists experienced the materials needed for stoma care, these figures do not take
problems after surgery. Nordstrom and Nyman (1991) reported into account any extra costs that treating complications may
that 90% of male urostomists experienced impotence, while incur.These may include additional medications or treatments,
the female participants reported little or no sexual activity referral on to other specialities, such as dermatology and,
after surgery. However, it is worth noting that those patients importantly, nursing time and resources needed to assess and
care. By placing the patient at the centre of that care, delivered England. http://bit.ly/2bDAU9D (accessed 19 June 2016)
Herlufsen P, Olsen AG, Carlsen B et al (2006) Study of peristomal skin
in a timely way and with a basis in robust evidence, the CNS disorders in patients with permanent stomas. Br J Nurs 15(16): 854–62
remains key in championing these positive outcomes. This Hill JR, Wertz PW (2009). Structures of the ceramides from porcine palatal
stratum corneum. Lipids 44(3): 291–95. doi: 10.1007/s11745-009-3283-9.
enables patients to concentrate their efforts on building their James WD, Berger TG, Elston DM (2006) Andrews’ diseases of the skin: Clinical
confidence and wellbeing freer from the concern of pouch Dermatology (10th edn) Elsevier Saunders, Philadelphia
Kanitakis J (2002) Anatomy, histology and immunohistochemistry of normal Pitmann J, Kozell K, Gray M (2009) Should WOC nurses measure health-
human skin. Eur J Dermatol 12(4): 390–401 related quality of life in patients undergoing intestinal ostomy surgery? J
Leenen LP, Kuypers JH (1989) Some factors influencing the outcome of Wound Ostomy Continence Nurs 36(3): 254–65
stoma surgery. Dis Colon Rectum 32(6): 500–4 Ratliff CR, Scarano KA, Donovan AM, Colwell JC (2005) Descriptive study
Lober CW, Fenske NA (1991) Cutaneous ageing: effect of intrinsic changes on of peristomal skin complications. J Wound Ostomy Continence Nurs 32(1):
surgical considerations. South Med J 84(1): 1444–46 33–7
Lyon C (2013) The problem stoma – peristomal skin problems. http://bit. Richards GM, Oresalo CO, Halder RM (2003) Structure and function of
ly/2aSs6eY (accessed 13 May 2016) ethnic skin and hair. Dermatol Clin 21(4): 595–600
McMullen CK, Wasserman J, Altschuler A et al (2011) Untreated peristomal Richbourg L, Thorpe JM, Rapp CG (2007) Difficulties experienced by the
skin complications among long-term colorectal cancer survivors with ostomate after hospital discharge. J Wound Ostomy Continence Nurs 34(1):
ostomies. Clin J Onc Nurs 15(6): 644–50 70–9
McNichol L, Lund C, Rosen T, Gray M (2013) Medical adhesives and Rudoni C, Dennis H (2009) Accessories or necessities? Exploring consensus
patient safety: state of the science: consensus statements for the assessment, on usage of stoma accessories. Br J Nurs 18(18): 1106–12
prevention, and treatment of adhesive-related skin injuries. J Wound Ostomy Salvadalena G (2016) Peristomal skin conditions. In Carmel JE, Colwell JC,
Continence Nurs 40(4): 365–80 Goldberg MT (eds) Wound, Ostomy and Continence Nurses Society Core
Muldoon MF, Barger SD, Flory JD, Manuck SB (1998) What are quality of life Curriculum: Ostomy Management. Wolters Kluwer, Philadelphia
measurements measuring? BMJ 316(7130): 542–5 Shellito PC (1998) Complications of abdominal surgery. Dis Colon Rectum
Nair CK, George PS, Rethnamma KS et al (2014) Factors affecting health 41(12): 1562–72
related quality of life of rectal cancer patients undergoing surgery. Indian J Timmons J (2006) Skin function and wound healing physiology. Wound
Surg Oncol 5(4): 266–73 Essentials 1: 8–17
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIH) Tortora G, Derrickson B (2009) Principles of anatomy and physiology: organization,
(2016) http://bit.ly/2aY1ISi (accessed 1 June 2016) support, movement and control systems of the human body (12th edn). JohnWiley
Neuman HB, Park J, Fuzesi S, Temple L (2012) Rectal cancer patients’ quality & Sons, New Jersey
of life with a temporary stoma: shifting perspectives. Dis Colon Rectum Turkington C, Dover J (2007) Skin Deep (3rd edn) Checkmark Books, NYC
55(11): 1117–24 Voegeli D (2012) Moisture-associated skin damage: aetiology, prevention and
Neuman HB, Patil S, Fuzesi S et al (2011) Impact of a temporary stoma on the treatment. Br J Nurs 21(9): 517–21
quality of life of rectal cancer patients undergoing treatment. Annals Surg White CA, Hunt JC (1997) Psychological factors in postoperative adjustment
Oncol 18(5): 1397–403 to stoma surgery. Ann R Coll Surg Engl 79(1): 3–7
Nightingale J, Woodward JM on behalf of Small Bowel and Nutrition White M (2014) Using silicone technology to maintain healthy skin in stoma
Committee of the British Society of Gastroenterology (2005) Guidelines care Br J Nurs 23(22): 16–20
for management of patients with a short bowel. Gut 55(suppl 4): iv1–12 Williams J (2006) Stoma care part 2: choosing appliance accessories.
Nordström GM, Nyman CR (1991) Living with a urostomy. A follow up with Gastrointestinal Nursing 4(7): 16–9
special regard to peristomal skin complications, psychological and sexual Woo KY, Sibbald RG, Ayello EA et al (2009) Peristomal skin complications
life. Scand J Urol Nephrol Suppl 138: 247–51 and management. Adv Skin Wound Care 22(11): 522–32
Nugent KP, Daniels P, Stewart B et al (1999) Quality of life in stoma patients. Wysocki AB (2012) Anatomy and physiology of skin and soft tissue. In Bryant
Dis Colon Rectum 42(12): 1569–74 R, Nix D (eds) Acute & chronic wounds: current management concepts (4th edn)
Persson E, Hellström AL (2002) Experiences of Swedish men and women 6 Elsevier Mosby, St Louis
to 12 weeks after ostomy surgery. J Wound Ostomy Continence Nurs 29(2): Zhai H, Maibach HI (2002) Occlusion vs barrier function. Skin Res Technol
103–8 8(1): 1–6
This practical and user-friendly book is made up of articles from a popular series in Practice
essential collection of common
dermatological cases encountere
d in everyday practice with concise
content on the aetiology, diagnosis,
management and prevention
so that healthcare practitione
rs can effectively treat their patients.
Nursing and covers: the aetiology, diagnosis, management and prevention of most common Importantly, this book also examines
patient care, with considerat
ion for how
other issues that impact
factors impact patients and treatment social and psychological
of skin conditions.
dermatological cases; social and psychological factors and their impact on patients and This book comprises updated
highly popular series published
articles from a long running and
in the Practice Nursing journal
the differential diagnosis of dermatolo on
Highly illustrated, with colour pictures throughout, helps to aid diagnosis. Each chapter is About the author
Dr Jean Watkins is a retired GP
Dermatology
and remains an active member
Practice Nursing Editorial Board of the
presented in a user-friendly format making this a highly practical text for nurses and GPs.
and, in April 2004, was awarded
Fellowship of the Royal College a
of General Practitioners.
ISBN-13: 978-1-85642-401-1; 297 x 210 mm; paperback; 200 pages; publication 2010; £29.99 Differential
© 2016 MA Healthcare Ltd
Diagnosis
Jean Watkins
ISBN 1-85642-401-4
Jean Watkins
Order your copies by visiting or call our Hotline 9 781856 424011
QB DermaDiffs cover.indd
1
05/08/2010 12:12