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• Plaques
• Tangles
hypothesis”.
• However, there is growing evidence for the role of additional factors
such as oxidative stress, neuroinflammation, and mitochondrial
dysfunction in the pathogenesis of AD.
DIAGNOSIS:
• Detailed patient history
• Information from family and friends
• Laboratory tests like:
Rule out vit B12 and folate deficiency
Rule out hypothyroidism with TFT tests
Blood cell count , serum electrolyte and LFT
• Other diagnostic tests:
CT, PET or MRI scans may aid diagnosis.
• Currently, clinical diagnosis of AD is based on the National Institute of
Neurological Disorders and Stroke—Alzheimer’s Disease and Related
Disorders Association (NINCDS–ADRDA) criteria.
They can detect the patients with AD in their preclinical stage, monitor
the disease progression.
TREATMENT:
There is NO CURE for
Alzheimer’s disease!!!
Primary goals of therapy are: