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Abstract —The purposes of this research are to result and show the validity and practicality of biology
module with spiritual nuance on human reproduction system material for Senior High School students.
This research used 3 steps from 4D Models those are define, design, and develop. The subjects of this
research were 6 validators, 2 teachers, and 20 students class XI from Madrasah Aliyah Ar-Risalah,
Padang. Data in this research was primary data collected from validity and practicality questionnaire. The
result of validity was 83,85% in criteria valid, practicality by teachers was 80,00% i n c r i t e r i a
p r a c t i c e , and p r a c t i c a l i t y b y students w a s 83,96% in criteria practice.
Keywords — module, spiritual nuance, human reproduction system material,
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