Full Name : Naeny Fajriah

Phone Number : 082266609871

Title : Association Of Bacterial Vaginosis And Progesterone 
Levels On The First And Second Trimester 
Of Pregnancy
E-mail : fajriahnaeny@yahoo.com

ASSOCIATION OF BACTERIAL VAGINOSIS AND PROGESTERONE

LEVELS ON THE FIRST AND SECOND TRIMESTER OF PREGNANCY
Naeny Fajriah1, Andisa Fadhila2, Maisuri T Chalid1
1
Bagian Obstetri dan Ginekologi
2
Fakultas Kedokteran Universitas Hasanuddin Makassar
Abstract
Introduction:
Bacterial vaginosis (BV) is a clinical syndrome due to the change of Lactobacillus
spp, which is the normal vaginal flora with a high concentration of anaerobic
bacteria. The role of progesterone in the prevention of preterm delivery involves
its capacity to promote anti-inflammatory and pro-relaxant pathways in the uterus
thereby reducing uterine contractility. We hypothesized that progesterone would
promote Lactobacillus spp. Dominance. Our aim is to find the association between
progesterone levels with the incidence of bacterial vaginosis in the first and second
trimester pregnant women.
Method :
Cross-sectional study, using a pregnant women in the first and second trimester.
The sample consisted of 77 pregnant women who came for antenatal care with
vaginal discharge, from January – April 2018. Statistical analysis using chi-square
test.
Results :
No significance difference of Progesterone levels between BV and non BV group
p = 0.233), while age, parity, education and occupation had no significant
association (p> 0.05). Analysis of the progesterone levels with Amsel criteria, it
was found that vaginal pH were found to have significant associations with
progesterone levels (p=0.039, RR 2.095, 95% CI 1.003-4.554).
Conclusions :
There was a significant association between high levels of progesteron in first
trimester of pregnancy with the incidence of bacterial vaginosis.
Key Words :
bacterial vaginosis, progesterone Levels, lactobacillus, gestation