Heal HIV With Lifeone Therapy

The HIV virus is parasitic. This virus requires selenium, cysteine, glutamine, and tryptophan to replicate.
The human body uses these same four nutrients to create a critical anti-oxidant glutathione peroxidase
(GP).When HIV virus consumes these nutrients severe deficiencies of these four substances and GP
result. These deficiencies are responsible for many of the symptoms of HIV infection (collapse of the
immune system, muscle wasting, dermatitis, diarrhea, neuritis and dementia). Deficiency of selenium is a
more accurate predictor of mortality in HIV infection than is the traditional CD4 T cell count. A fall in
selenium reduces the CD4 T cells because selenium is critical for lymphocyte production.

HIV has difficulty infecting persons who are not selenium deficient and can only progress to AIDS in
persons who have low selenium blood levels. Therefore it appears prudent for patients with a positive
serology for HIV to take 400 mcg of selenium daily if blood selenium levels are low or symptoms
compatible with AIDS infection are present.

The African Country of Senegal with its very high intake of selenium from food grown in high selenium
soil has always had a very low incidence of cancer. A dose of 200 mcg daily of selenium when taken on a
long term basis was proven able to prevent about 50%1 of cancers in the USA. If instituted this simple
measure could save 100,000 lives a year in the USA. Be sure your vitamin preparation contains this
quantity of selenium.

HIV in Uganda and Senegal

AIDS has had a devastating impact in the African nation of Uganda probably worse than any other nation
in the world. Some villages had no surviving adults over the age of 35. Many families had teenagers
raising children and functioning as parents because the parents were deceased.

The nation of Senegal, which has soil containing unusually large amounts of selenium, had only a .5%
HIV incidence in a prenatal clinic in Dakar in 1998. This low prevalence has remained consistently at
1.0% or less since then. The promiscuous sexual practices in Senegal and Uganda are identical.
However, Uganda has low levels of selenium in the soil and there was a 31%2 incidence of HIV in a
prenatal clinic in Kampala in 1990. This suggests that soil containing large amounts of selenium may be a
major factor in protecting citizens from HIV infections.

One of the fascinating findings in HIV patients is that profound, fatal infections can result from infections
with organisms that are considered to be non-pathogenic or of minimal pathogenicity in healthy persons.
This certainly reflects the loss of immune function caused by the HIV virus magnified by loss of ability to
produce glutathione Peroxidase (GP) which is a potent anti-oxidant. When deficient GP leads to oxidative
stress, extensive free radical damage, destruction of cell membranes, and short life expectancy

utritional Therapy Can Control HIV Infections

Dietary Therapy With Selenium And utrients

The simplest effective therapy for HIV may turn out to be dietary restoration of selenium, cysteine,
glutamine, and tryptophan. Such restoration relieves the symptoms of immunosuppression, muscle
1
Clark, Larry M.D. JAMA December 1996
2
Foster, Harold D. What really causes AIDS pg 14 2002 Trafford Publishing 1-250-383-5864 sales@trafford.com
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wasting, dermatitis, diarrhea, and dementia. Repletion of selenium improves immune function. Taking
cysteine improves glutathione levels, which improves T and B lymphocyte function. Glutamine
supplementation restores muscle mass and stops the abnormal permeability of the intestine. Lack of
tryptophan and its synthesized niacin and serotonin causes diarrhea, dementia, dermatitis, and death.
(pellagra). Raising the serotonin level inhibits the multiplication of HIV in T4 lymphocytes. Niacin slows
the progression of HIV to AIDS. However, this dietary approach to HIV infection does not cure HIV. As
soon as the dietary program ceases the patient begins to revert into an ill patient with HIV infection.

The HIV virus can only replicate by seizing selenium, cysteine, tryptophan and glutamine away from the
HIV infected host. This over time this leads to steady erosion of levels of these substances and HIV
symptoms begin. These same 4 nutrients in healthy persons create Glutathione Peroxidase GP which is a
key antioxidant in the human body. Deficiency of GP causes extensive free radical damage, oxidative
stress, lack of defense in the body against the destructive process known as lipid peroxidation which
destroys cell membranes, and decreased life expectancy. T cells lacking GP accumulate lipid
hydroperoxides which stimulate programmed cell death(apoptosis) thus decreasing the quantity of
available T lymphocytes.
Synergistic Action Of LifeOne
Synergy is defined as the interaction of two or more agents or, in this case, phytochemicals so that their
combined effect is greater than the sum of their individual effects. To understand and develop this
complex compound took a great deal of skill. Development of this product required knowledge of the
actions, proper dosages, and favorable interactions involving multiple naturally occurring minerals,
organic plant phytochemicals and liposomes. This knowledge resulted in a product able to contain
effective doses which obtain more favorable results than normally anticipated by the individual
constituents. LifeOne was developed by a clinician who is a herbal expert. His skillful combining of
phytochemicals and other ingredients such as selenium, permitted truly safe and effective doses to obtain
better results. This results in lower costs as well as better results with greater safety.

Curcumin (Tumeric Extract) and Resveratrol lower insulin resistance. This results in improved
metabolism and lower glucose levels. Chrysin binds to estrogen receptors which improves metabolism by
reversing the adverse effects of estrogen excess. Some compounds in LifeOne that have known
synergistic effects are: Diindolylmethane (DIM), Colorius Versicolor, Curcumin (Tumeric Extract),
Green Tea Extract, Chrysin, Quercetin, Resveratrol and Selenium. These components are also carried in a
liposomal base which enables them to be promptly absorbed to be used by the body, rather than being
broken down in the digestive tract.

As an example, one of the components of LifeOne is selenium. The people of Senegal have a very high
intake of selenium, from food grown in high selenium soil. LifeOne uses selenium in the form of Seleno
L. Methionine. This is the most easily assimilated form of selenium.. Its delivery is also enhanced by its
encapsulation in a liposomal matrix. It must be noted however, that selenium alone will not cure AIDS or
cancer. It is the synergy of all of the complex components that make LifeOne unique in its long term
effectiveness.

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 Liposomal Delivery System
Many patients with HIV have diarrhea, impaired absorption of nutrients, and serious weight loss. The
liposomal delivery system took 3 years to perfect. As now constituted it bypasses the HIV damaged
intestine by promptly delivering the LifeOne to vascular and lymphatic vessels where it is quickly
absorbed. This results in higher prolonged blood levels of the nutrients. This makes LifeOne more
efficacious so that weight loss is reversed and recovery of good health is expedited.

LifeOne is a very sophisticated product that took years to develop. The synergism of the products used
permits lower doses to be more effective. The liposomal delivery system took three years of work before
it was perfected. This system produces higher cellular uptake and prolonged circulation of the therapeutic
agents. The water used has no detectable impurities. The company has an outside laboratory analyze all
herbs for rigid specifications before they are purchased. The herbs are then placed in a nitrogen
environment until used for production of LifeOne. This prevents any deterioration of the herb as oxidation
cannot occur in an oxygen free environment. The final product is so complex and the quality of
ingredients is so stringent it would be nearly impossible to duplicate. The clinician developer of Lifeone is
a herbal expert who is highly skilled at formulating products.

LifeOne is composed of natural phytochemical plant compounds and herbal extracts known to have a
positive effect on individual lymphocyte cell lines and to stimulate the debilitated immune systems of
HIV positive patients with AIDS and malignancies. These plant products include: chrysin, resveratrol,
green tea extract, quercetin, curcumin, di-indolymethane, and coriolus versicolor. The product also
contains L-Selenium Methionine. All of the constituents are carried in a specially designed liposomal
base to facilitate direct absorption into the lymphatic system. LifeOne has 2 U.S. patents as an immune
healing substance.

Clinical Results in 4 Patients

This paper reports the lab data and patient findings over the first four months. During that time HIV-
1(RNA) dropped an average of 70% within 38 days, with 3 out of 4 of the patients averaging a 93% drop
in an average 38 days. Absolute lymphocyte count increased an average of 445 cells/ml. CD3+ increased
an average of 344 cells/ml. CD4+ increased an average 168 cells/ml. CD8+ increased an average 175
cells/ml. CD4+/CD8+ increased an average of 0.12. There was improvement in fasting blood sugar
values from 109 mg% to 95 mg%. Fasting cholesterol values fell from 231 mg% to 200 mg% in 4
months.

No side effects were seen in these 4 patients. The falling cholesterol values were felt to be related to
improved metabolism produced by quercetin in the formulation. Lower blood sugar values reflect
improvement in estrogen excess resulting from chrysin binding to estrogen receptors sites, anti-estrogen
effects from di-indolymethane and the decrease in insulin resistance brought about by resveratrol.

Many current pharmaceutical therapies for AIDS are both expensive and full of undesirable side effects.
This small study was designed to compare the results of a high quality nutrient formulation (LifeOne)
with current AIDS therapies.

HAART Therapy for AIDS

Highly active antiretroviral therapy (HAART) in the treatment of HIV-1 is associated with a decrease in
viral replication, often to undetectable levels and with an increase in CD4-T lymphocytes (helper T-cells).
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Unfortunately residual HIV-1 replication recurs with incomplete recovery of CD8-T lymphocytes
(cytotoxic, natural killer cells). (1) The initial increase in CD4+ cells is accompanied by a proportionally
larger drop in CD8+ cells.

The CD8+ cells are an essential factor in inducing CD4-T cells to increase production of Interferon
gamma and FAS-Ligand. These two molecules are critical to long term CD8+ function in the killer cell
mode in HIV-1. (2)

In contrast, LifeOne herbal formula, a natural phytochemical immune system booster therapy, increased
absolute lymphocyte cell counts, increased CD3+, increased CD4+, and increased CD8+ while decreasing
HIV-1 viral load 70% in 42 days.

Normally CD3+ cells are mature T-cells and natural killer cells. In HAART studies CD3+ levels drop or
are not measured, according to Willard-Gallo, K et al (4). HIV-1 retrovirals incapacitate their T-cell host
by interfering with the CD3+ antigen activation pathway. CD3+ lymphocyte counts increased an average
of 1895 cells/ml in 42 days.

Recently many serious side effects of HAART have been recognized. In particular, a syndrome of
Lipodystrophy (peripheral fat loss and/or abdominal obesity) and Hyperlipidemia occurs in 60 to 80% of
patients treated with HAART. (5, 6) Hyperinsulinemia, insulin resistance, and impaired glucose tolerance
have all been observed. This chronic and progressive disorder can lead to diabetes mellitus Type 2.
Increases in triglycerides and VLDL associated with HAART are very disconcerting and the impact on
cardiovascular disease has to be a serious concern.

The metabolic effects of LifeOne when combined with a low glycemic diet are clearly beneficial resulting
in an improved lipid profile and lowered average serum glucose levels. Glucose dropped 10%,
cholesterol dropped 30% and triglycerides dropped 40% in an average of 42 days.

This herbal formula synergistically combines a proprietary blend of herbal extracts and phytochemical
compounds with a liposomal delivery system in an easy to administer suspension. The ingredients include
Chrysin, Coriolus versicolor, Diindolylmethane, Resveratrol, Tumeric Extract, Green Tea Extract,
Quercetin, and L-Selenium Methionine.

Many patients with advanced immune deficiency disorders have been returned from bed ridden states to
good health with LifeOne.

CASE REPORTS

The patients were seen by Dr. A. who did the initial histories and physical examinations. All patients
received a metabolic profile, complete lymphocyte subset panel, HIV-1(RNA) viral load, and complete
blood cell counts.

Extensive counseling in a low glycemic diet was provided (no sugar, pasta, rice, corn, white potatoes,
bananas, bread). Fresh vegetables, lean meat, fish, chicken and fruit were encouraged. Dairy products
were largely eliminated. Whey isolate protein up to 100 grams daily was strongly recommended to help
reverse their protein depleted state. The patients drank distilled water about 90 ounces daily. Prill bead
water would be even more valuable.

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LifeOne therapy one ounce three times daily after meals was initiated. Laboratory tests were repeated
every thirty days. Patients were seen at 2 week intervals for a month and then had monthly visits
thereafter.

Patient #1 9/28/02
This 24 year old male was diagnosed with AIDS in December 1996 when he was admitted to Bajanor
Hospital with acute pneumonia, severe respiratory insufficiency, and an extreme state of cachexia. A
diagnosis of pulmonary tuberculosis had been established in 1977 after a right submaxillary biopsy
confirmed the presence of tuberculosis. He was treated with Ethambutol, Rifampin, and Streptomycin.
His condition improved and he did relatively well until 1998 when he complained of severe fatigue. In
February 1999 he began treatment for HIV with Epivir, Cerik and Sustiva. His primary complaints were
severe bouts of diarrhea and fatigue. The patient contracted HIV-1 Virus through passive, promiscuous
homosexual contact.

Physical Exam- Wt. 164lbs. Ht. 5ft. 4in. B.P. 120/80 P.76 R.R.20
Complete physical examination was performed with no abnormalities detected.

11/8/02 Progress note- B.P. 90/60, Pulse 78, Resp. 20, Temp 36.9 C
He feels much more energetic, which he attributes to the herbal formula. He reports having had a dry
cough.

12/8/02 Progress note- B.P. 110/70, Pulse 87, Resp. 24, Temp 36.5 C
Has noticed a marked increase in energy. The preliminary clinical studies show improvement in relation
to CD4+ and viral load. He sustained a closed fracture of the left ankle in an escalator fall that required a
cast and 3 days of hospitalization.

01/8/03 Progress note- B.P. 120/80, Pulse 70, Resp. 20, Temp 37.2 C.
No unusual findings.

Patient #2 10/3/02 Initial Consultation

This 26 year old male was diagnosed with AIDS in September 1999. He initially
presented with pulmonary tuberculosis which was treated for 6 months with INH and ethambutol. He
also had prophylaxis with trimethoprim sulfamethoxazole after being diagnosed with meningitis the same
year.

Physical Exam- Wt.186, Ht. 5ft. 5in. B.P. 125/85, P.68, R.R.22, Temp 36.7 C.
Complete physical examination was performed with no abnormalities detected.

10/24/04 Progress note- B.P.120/80, Pulse 78, Resp. 22, Temp.36.7 C.

Patient relates having had slight diarrhea which now is under control. He says he has a great deal of
energy,

11/8/02 Progress note- B.P.120/80, Pulse 73, Resp. 19, Temp. 37.1C
He claims to feel very well, with higher energy levels.

11/18/02 Progress note-

Laboratory studies show increase in CD4+ from 150 to 225. Also his CD8+ increased from 150 to 326.
The HIV-1 viral load decreased from 67,400 to 4,010.

11/26/02 Progress note- B.P. 120/70, Pulse 72, Resp. 20, Temp. 36.8
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He has high activity and energy levels.
He continues on 1 ounce of LifeOne, three times daily. At the end of the first 30 days the dosage
may be reduced to 1/2 ounce three times daily.

12/5/02 Progress note-

No symptoms

Patient #3 10/14/02 Initial Consultation

This 48 year old male patient positive for the HIV-1 virus was diagnosed in 1997 after his wife died of
complications of pneumonia and AIDS. The patient is heterosexual and became infected through his wife
who had been infected by a previous partner.
At this time this patient has no manifestations or symptoms of immunosuppression or incapacitating
infirmities related to HIV-1. He presents having been treated with anti-retrovirals as follows:
Norvir- Ritonavir 2 every12 hours
Crixivan and Indinavir 2 every 12 hours
Videx- Didanosine 2 in the morning
Retrovir 1 q 12 hours
Sustiva and Efavirenz 3 at night
Novavir and Zidovudine 2 every 8 hours
He also takes multi-vitamins once a day. The patient presents with previous lab tests revealing an elevated
CD4+ and a non-detectable viral load. Our baseline tests, however, showed a depressed CD4+ of 117
cells/ml and a viral load of 2900.

Physical exam- B.P. 140/90, Pulse 82, Resp 23, Temp 36.9 C
Physical examination revealed loss of all teeth. The second heart sound was split.

11/22/02 Progress note-

Patient reports he feels better work capacity to work He feels his vitality has increased by 100%. The
laboratory results show improvement over previous laboratory tests.

Patient #4 10/15/02 Initial Consultation

This is a male patient 35 years old who has had HIV-1 since 1996. His HIV manifested with
pneumocystis carinii and Karposi’s sarcoma. He is homosexual and got the virus from sexual contact.
Presently, he is physically asymptomatic. He has taken retrovirals since 1996.

Physical exam- Wt.190, Ht.5ft.9in. B.P. 120/75, Pulse 68, Resp. 18, Temp 36.7 C
Complete physical examination revealed only dental caries.

Clinical plan-
Review of previous lab studies revealed that CD4+ values fluctuated between 526 and 867. Viral load is
43.600.

10/24/02 Progress note- B.P. 120/80, Pulse 78, Resp. 18, Temp 36.7 C
Patient feels increased energy with greater productivity at work.

11/22/02 Progress note-

Patient says he feels much better.

12/08/02 Progress note-

The preliminary clinical results show a significant reduction in his viral load and an increase in CD4+.
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Dosage Suggestions

The initial dose of Lifeone should be one ounce three times daily taken after meals. In one month if the
patient is obviously improving the dose of Lifeone can be reduced to one half ounce three times daily
following meals. After 3 months of LifeOne a viral load should be obtained. If there are no viruses
remaining LifeOne therapy should be continued for 6 more months before stopping. If viral particles are
still present the therapy needs to be continued until a full year of therapy has been completed.

Immune System Information

The immune system is amazingly complex. For ease of description, it can be divided into 2 parts, humoral
immunity, concerned primarily with production of antibodies, and cellular immunity, involving the
interaction of multiple cells that process information, recognize “self” and “other”, and effectively destroy
foreign invaders. With regards to HIV infection, we are primarily concerned with immune cells and
proteins coating the outside of the cells which are the target of the HIV virus. This protein is named CD4.
It is found on several cells of the immune system. The cell with the highest concentration of CD4 is
named the CD4+ T cell. The CD8+ cell is also rich in CD4 protein.

• The CD4+ T cell is the primary target of HIV but all other cells exhibiting the CD4 protein are
also adversely affected.
• The primary function of the CD4+ cell is as a helper cell that facilitates the functions of many
other cells of the immune system.
• CD8+ cells are the NK, natural killer cells that recognize and destroy cells presented to them that
are coated with foreign proteins. They may also suppress immune responses. Initially, in the acute
HIV infection, CD8+ cell numbers increase as the immune system is activated. Also acutely, the
numbers of CD8+ T cells may remain elevated or return to normal levels. But apparently
overwhelmed by the sheer numbers of viral particles, large populations of CD8+ cells simply
disappear followed by a decrease in absolute numbers of CD8+ T lymphocytes as the disease
enters the chronic phase.
• CD16+/CD56+ cells are another subpopulation of NK cells with the function of destroying foreign
invaders.
• Arrest of development or failure of function of one or more of these T cell subsets may result in
immunodeficiency or autoimmune diseases.
• Normally, the immune system remains in a state of equilibrium, becoming active when presented
with an invading organism. When the threat is cleared by an intact immune system, it returns to a
state of normalcy.
• The HIV infected immune system, however, is chronically activated. Chronic exposure of the
immune system to a particular viral invader over an extended period may ultimately lead to an
inability to sustain an adequate immune response to that invader. Furthermore, the ability of the
immune system to respond to a broad spectrum of viruses and other threats may be compromised
if the immune system is in a state of chronic activation.

Results of LifeOne Therapy of HIV Infections

Four patients with advanced cases of HIV infection were treated with LifeOne. All four proceeded to
recover from their symptoms of HIV infection. No patients had any side effects from LifeOne therapy.
LifeOne is a safe effective therapy for HIV infections. The product is a complex formulation that is
expensive to produce. Expense probably limits its use for HIV in impoverished nations. LifeOne therapy
is capable of quickly returning invalided HIV patients to normal health.
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Lifeone can be obtained from www.mynaturalhealthteam.com Phone 1-800-416-2806

Dr. James Howenstine’s book A Physician’s Guide To Natural Health Products That Work 831 pg. can
be purchased in hard cover for $39.95 and soft cover for $29.95 from my natural health team.

References
1. Costa, P., et al. Differential disappearance of inhibitory natural killer cell receptors during HAART
and possible impairment of HIV-1 specific CD-8 cytotoxic T lymphocytes. AIDS.200115 (8):965-74.
2. Scott, G., et al. Antiviral immune function of the CD-4 molecule on CD-8 T cells. Dept. of Medicine
UCLA AIDS on line.
3. Paper pending publishing.
4. Willard-Gallo, et al. HIV Infection and expression of the T Cell Receptor. Christian de Duve Institute
of Cellular Pathology.
5. Walli, R., et al.1998 Treatment with protease inhibitors associated with peripheral insulin resistance
and impaired oral glucose tolerance in HIV-1 infected patients. AIDS.12:f167-f173.
6. Viread handout from pharmaceutical manufacturer.
7. Abacavir handout from pharmaceutical manufacturer.

Dr. James A. Howenstine is a board certified specialist in internal medicine. The Second
Edition of his book A Physicians Guide To Natural Health Products That Work is available.

Dr. Howenstine can be reached by phoning 001-506-2262-7504.

E-Mail: dr.jimhow@gmail.com