Discover African Jobelyn

Antioxidant Powerhouse!

• Joint Health
• Immune System
Support
• Cardiovascular
Health
• Red Blood Cell
Development
Discover Jobelyn – A traditional
African preparation of Sorghum bicolor.
Blueberries, pomegranate, grapeseed, açai
berry… and many more. Everywhere
you turn, familiar and not-so-familiar
foods and herbs are touted for their
“antioxidant strength.” With all the buzz
about antioxidants these days, it can be
overwhelming to choose the one that is
right for you.
Besides, what are antioxidants? How can
they be so helpful for so many health
conditions? Are they just a trendy health fad?
Let’s answer those questions while looking
at one antioxidant source in particular that
could provide you and your family with
incredible health-changing benefits.
B
oth in its African homeland and in North America, a folk remedy
herbal extract has recently caught the attention of medical
researchers. Sorghum bicolor is a grain long known for its high
nutritional value. But only a special traditional extract of the leaf sheath
draws out the plant’s incredible health benefits.
African tribal culture has long touted the extract for its value in helping
people who struggle with anemia, heart disease, joint pain, and poor
immune system response. Today’s scientific studies are quickly confirming
those folk uses. Yet, one must ask, “How can a single herbal ingredient
help with such a broad range of conditions?”
The secret is the extract’s sky-high antioxidant rating and anti-
inflammatory effects. One company has made Sorghum bicolor leaf extract
available to the U.S. market under the name Jobelyn™. The product has
an Oxygen Radical Absorbance Capacity (ORAC) of 3,123 µmoleTE/g.
That’s three times that of açai berries! Complementing that antioxidant
rating is Jobelyn’s anti-inflammatory effect. The extract has demonstrated
selective COX-2 inhibition, providing effective reduction in inflammation
without the side effects of common prescription medications.
In short, all the conditions that Jobelyn addresses look unrelated, but they
actually have two major factors in common. They are all tied closely to
underlying states of cyclical inflammation and oxidative damage. Let’s
take a closer look at oxidative and inflammatory processes in the body.
Then it will be easier to understand how the extract supports such a
wide variety of systems and functions.
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Antioxidants: Inflammation:
Working to protect the body on a cellular level When the body’s crisis switch gets stuck in the “on” position
Oxidation. We know it’s a bad Jobelyn, a traditional Sorghum bicolor leaf The other core benefit of Jobelyn is its anti-
thing for the body, and doctors extract demonstrates an ORAC rating two times inflammatory effect. It’s important to have a
tell us to eat lots of antioxidant the total value of 13 antioxidant foods!
basic understanding of the inflammation process.
fruits and vegetables. But how (ORAC) per mg. Typically, when inflammation first occurs, it’s a
does oxidation happen anyway? Blueberries 24.00 mmoleTE/g good thing. Inflammation is the body’s standard
Plums 9.49 mmoleTE/g
We need oxygen for life. Our response to injury or infection. When there’s
Blackberries 20.36 mmoleTE/g
lungs take it in, and a complex Oranges 7.50 mmoleTE/g
a crisis in the body—whether that’s a sprained
network of capillaries and Frozen Tart Cherries 20.33 mmoleTE/g ankle, a torn ligament, or a case of the flu—the
alveoli enable red blood cells Red Grapes 7.39 mmoleTE/g body gears up, sending extra white blood cells and other immune system
to acquire the oxygen and Açai Berries 997.00 mmoleTE/g components to the place or places where there is a problem. That’s
deliver it throughout the Strawberries 15.00 mmoleTE/g why an injury site swells up or your glands get big when you’re sick.
Dried Tart Cherries 68.00 mmoleTE/g
body. But, as oxygen is used Inflammation hurts, and the pain is the body’s way of demanding that
Tart Cherry Juice 128.00 mmoleTE/g
in various processes, tiny Concentrate you rest the injured part or get extra sleep.
electrons can break off. These Canned Water-packed 17.00 mmoleTE/g
Inflammation is an intelligent system that, when working properly,
unpaired electrons are called Tart Cherries

free radicals. Think of them as Prunes 57.70 mmoleTE/g
the waste product of cellular
Raspberries 12.20 mmoleTE/g
JOBELYN 3,123.00 mmoleTE/g
processes.
Jobelyn has more proven Oxidative Radical Absorbance Capacity
There are some processes (ORAC) than 13 well-known antioxidant-rich fruits–combined!
where free radicals are actually a good thing – for instance, to kill
bad bacteria in certain immune system functions. But, generally free
radicals are not helpful. They bounce around hitting cells and causing
damage, sometimes even breaking off portions of DNA. The grand
sum of this cellular damage is at the root of many health conditions
including cardiovascular challenges, poor immune response, and even the
appearance of wrinkles on the skin. This is the cumulative wear and tear
that results from simply living life. Oxidation is also aggravated by stress,
environmental factors, and poor diet.
The effects can be tempered though, through a diet and supplement
program rich in antioxidants. Just like it sounds, an antioxidant is a
substance that naturally combats oxidation. Antioxidants are substances
that bind up the stray electrons and render them harmless. Antioxidant
foods and dietary supplements are rated using the ORAC scale, which
is a measure of the substance’s ability to absorb free radicals. When
compared to other recommended antioxidant foods, Jobelyn boasts
one of the highest food-source ORAC ratings known. That makes it a
superior choice for antioxidant supplementation.
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initiates the first healing stages in response to an injury or illness.
However, sometimes the inflammation cycle won’t calm down. One
of the most common examples is that of a joint injury that continues to
cause pain long after the original injury has healed. An ongoing state of
inflammation can take the shape of degenerative diseases like arthritis. A
hair trigger inflammation response is also at the core of allergic reactions
and many asthma cases. So, not all inflammation is bad. But when
inflammation won’t stop, or it happens in an unproductive manner (ie.
allergies, asthma, rheumatoid arthritis), it can drastically limit people and
threaten their quality of life.
Scientists have found a group of enzymes involved in inflammation and
other processes in the body. These enzymes are referred to as the COX
(Cyclooxygenase) enzymes. One in particular, COX-2, is a major player
in the bio-chemical cascade that results in inflammation and resulting
pain.
Common non-steroidal anti-inflammatory drugs (NSAIDs) inhibit all
COX enzymes. This is called non-selective COX-inhibition. Ongoing
use typically results in unwanted side effects such as peptic ulcers—an
inflammatory condition in itself. That’s a sad situation; having decreased
inflammatory pain in one part of the body, you wind up inadvertently
causing inflammation elsewhere!
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This is where Jobelyn comes in. Thankfully, some natural herbal sources
have been found to exhibit selective inhibition for COX-2 only—the
COX enzyme that is most active in the inflammation process. The
traditional African extract of Sorghum bicolor is one of these herbal
sources. Acting as a proven selective COX-2 inhibitor, Jobelyn soothes
the inflammation cycle and brings it to a centered state.1, 2 Rather than
acting as a pain-killer only, masking the symptoms, it works at the level of
the inflammation process itself hindering COX-2 activity. This selective
COX-2 inhibition results in a steady reduction of inflammation and pain,
without the unwanted side effects common with NSAIDs.
Applying the Science:
How Sorghum bicolor leaf extract helps specific conditions
Blood Cell Health – Jobelyn provides
strong antioxidant support for red blood cells.
Understanding the oxidation process, it’s easy to
see how red blood cells might be particularly
vulnerable to the damaging effects of oxygen
radicals. Red blood cells are the body’s oxygen
carriers. In the course of their 120-day lifespan,
they are constantly in contact with this double-
edged sword – the element that we require for life, which is also the
origin of oxidation. Adding to the challenge is the fact that mature red
blood cells do not have a nucleus, so they cannot produce new proteins in
response to oxidative damage. One way to support red blood cell health
is to prevent oxidation through strong antioxidant supplementation.
Antioxidant supplementation is especially important for people whose
red blood cell health is compromised due to anemia, including Sickle
Cell Disease. Recent scientific studies have looked specifically at the
effects of Jobelyn on anemia and found that it effectively increases packed
cell volume (PCV – the sheer number of blood cells) and hemoglobin
concentration (Hb – an indicator of red blood cell health).3-7 Preliminary
human clinical research in Nigeria has confirmed these results, showing
some beneficial effects after just a week of supplementation and significant
improvements for 102 of 113 patients after 6 weeks.8
In the case of Sickle Cell Disease, not only does Jobelyn help in its
antioxidant activity, but its anti-inflammatory properties may be of
.4
benefit too. Some researchers believe that sickle red cells can provoke
inflammation throughout the circulatory system because the deformed
cells physically hinder smooth blood flow.9 Jobelyn works both at the
level of protecting the red blood cells from oxidation and on the level of
protecting the circulatory system from the inflammation state that can
create even more free radicals. This herbal remedy cuts off the cycle of
oxidation and inflammation that aggravates sickle cells. While it can’t
cure the physical shape and structure of the sickle cells, it can lessen the
damage and effects of the cell deformity.
Cardiovascular Health – Seeing how helpful
Jobelyn is for the stressed circulatory system in
Sickle Cell Disease patients, it’s a small step to
recognize how helpful it is for cardiovascular
health in general. The medical community
now views free radical oxidation and ongoing
inflammation as primary contributors to heart
disease, cholesterol build-up, and arteriosclerosis (severe thickening and
hardening of artery walls).
Just as red blood cells are exposed to lots of free radicals, so are heart
and blood vessel cells. Heart cells also have the added stress of being
involved in constant contraction. This muscle activity produces plenty
of free radicals as a byproduct. Antioxidant protection is vital for the
cardiovascular system.10
Not only do antioxidants prevent damage to individual cells, they can
also prevent the breakdown of nitric oxide (NO). NO is a gas naturally
produced in the cardiovascular system, which helps promote relaxation
and expansion of the blood vessels. By supporting NO, antioxidant
supplementation can enhance blood flow. This explains why Jobelyn has
been found to enhance circulation.11
The cardiovascular system also benefits from Jobelyn’s anti-inflammatory
effects. Fatty plaque build-up in blood vessels often occurs due to low-
grade inflammation and irritation throughout the vessel walls. This
inflammation makes it easier for cholesterol particles to stick to the
lining of the blood vessels. Reducing inflammation can actually lower
the incidence of atherosclerosis (fatty plaque deposits) and coronary
events.1, 2, 10
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 Joint Health – Just as oxidation and inflammation
are at the core of blood cell and cardiovascular
health threats, this troublesome duo is also
involved in causing joint degeneration and pain.
The intricate connective tissue and surfaces
of our joints are under constant challenge
from daily use. Ongoing wear and tear, along
with occasional injury, result in plenty of free radical production and
inflammation. Without antioxidant support and balancing of the
inflammation process, the result can be achy joints and limited range of
motion.
We’ve touched on the role of Jobelyn as a powerful antioxidant and a
very selective COX-2 inhibitor. Jobelyn has also demonstrated an ability
to inhibit the release of pro-inflammatory proteins called cytokines. We
learned how the combination of anti-inflammatory and antioxidant
support results in dramatic improvements for the cardiovascular system.
The same benefits can improve joint health too.
In the joints, inflammation and oxidation create a self-reinforcing cycle.
Inflammation creates oxygen free radicals as a byproduct, which can in
turn cause more damage, which creates more inflammation, and so the
cycle goes. Sorghum leaf sheath extract, which provides both antioxidant
and anti-inflammatory effects, has been found to bring a dynamic end
to this cycle.1, 2
A reduction in inflammation and pain means more range of motion and
the freedom to work the joint and build strength. Strength-building
through physical therapy helps prevent future injury. By ending a
damaging pain cycle, Jobelyn has been found to begin a positive cycle of
improving joint health especially when combined with an appropriate
exercise program.
.6
Immune System Response – It takes a little
more explanation to understand how Jobelyn
supports the immune system. As with the case
of red blood cell health, we need to drop down
to a cellular and molecular level and think very
small. It’s the antioxidant activity that is most
vital for immune system support. Specifically,
the extract provides components for the body to build its own super
antioxidant: glutathione peroxidase.
The body creates glutathione and uses it for several protective
tasks including protecting certain immune system cells called CD4
T-lymphocytes. Glutathione contains selenium and three amino acids
(cystein, glutamine, and tryptophan). Jobelyn contains all three of these
amino acids, providing the body with some major building blocks of
glutathione.
Scientists believe this explains some astounding research coming out of
Africa right now. In a preliminary human clinical study involving HIV-
positive patients, Jobelyn supplementation improved compromised CD4
cell counts (30-300/1) by 200-300%. Those with initial CD4 counts
greater than 300 also saw an increase of 20-30%. The increase in cellular
immunity occurred regardless of whether the patient was taking other
antiretroviral drugs.12
Jobelyn is incredibly beneficial for the immune system when the body
is under one of the heaviest attacks imaginable. It makes sense that the
herbal would be helpful as a general immune system boost for anyone
in fine health. Its effects appear to be moderated too; meaning it won’t
make the immune system become overactive. That’s why we see such a
dramatic increase for those with very compromised CD4 counts and a
moderated increase for those who had higher initial counts. So, Jobelyn
is a safe immune support supplement whether you’re looking for a little
extra help during cold and flu season, or if you’re facing a much more
daunting immune system challenge.
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Taking Action: Jobelyn – Heart Health Formula
Which Sorghum bicolor product is right for you?
A blend of Sorghum bicolor leaf extract with hawthorn
Worldwide,there are remarkably few manufacturers producing antioxidant
berry extract and alpha lipoic acid. The combination
sorghum leaf extract. But, in the United States, there is one reputable
supports healthy heart rhythm and function along with
company that makes the extract available under the brand name Jobelyn.
providing overall antioxidant protection for the heart,
Named after the River Jubi region where the sorghum plant once grew
blood cells, and circulatory vessels.
wild, Jobelyn is produced under strict GMP standards and batch-tested
for purity and efficacy.
Supplement Facts Directions for Use:
Health Forever, the manufacturer who produces Jobelyn, offers the Serving Size: One (1) Capsule Servings Per Container: 60
Take one capsule, two or three
Sorghum bicolor leaf extract as a primary ingredient in four condition- times daily with a 12 ounce
Amount % Daily glass of water. May be taken
specific products: Per Serving Value regularly for ongoing support
Sorghum bicolor Leaf Powder. ............250 mg ** of cardiovascular health. In-
Hawthorn Berry Extract ...................... 80 mg ** crease daily water intake when
Jobelyn – Blood Builder Formula Alpha Lipoic Acid................................ 300 mg ** taking Jobelyn products.
**Daily Value not established
A blend of Sorghum bicolor leaf extract with additional
antioxidant alpha lipoic acid and herbal Eleutherococcus
senticosus. Together, these components support blood
cell production, promote blood cell and vessel integrity, Jobelyn – Joint Health Formula
and promote healthy cholesterol levels already within
the normal range.
A blend of Sorghum bicolor leaf extract along with the
Directions for Use: well-known joint health supplement glucosamine.
Supplement Facts Take one capsule, two or
These two ingredients provide synergistic joint and
Serving Size: One (1) Capsule Servings Per Container: 60 three times daily with a 12
ounce glass of water, for cartilage protection and support comfortable range of
Amount % Daily
Per Serving Value as long as immune system motion.
support is desired. May be
Sorghum bicolor Leaf Powder. ............250 mg **
taken regularly for ongoing
Alpha Lipoic Acid .............................. 300 mg ** support of blood building Directions for Use:
Eleuthero Root Extract....................... 500 mg ** activity. Increase daily water
Supplement Facts Take one capsule, two or three
intake when taking Jobelyn Serving Size: One (1) Capsule Servings Per Container: 60 times daily with a 12 ounce
**Daily Value not established
products. Amount % Daily glass of water. May be taken
Per Serving Value regularly for ongoing support
Sorghum bicolor Leaf Powder. .............. 250 mg ** of joint health. Increase daily
Glucosamine Sulfate................................ 80 mg ** water intake when taking
(from Glucosamine Sulfate Potassium) Jobelyn products.
**Daily Value not established

.8 9 ,
Jobelyn – Immune Support Formula
A blend of Sorghum bicolor leaf extract with additional
immune system supporting herbals Echinacea and
astragalus. May be taken regularly to keep the immune
system working at an optimum level or at the onset
of symptoms to help the body get over an infection
faster.
Directions for Use:
Supplement Facts Take one capsule, two or
Serving Size: One (1) Capsule Servings Per Container: 60 three times daily with a 12
Amount % Daily ounce glass of water for
Per Serving Value* as long as immune system
Sorghum bicolor Leaf Powder. .............. 250 mg ** support is desired. May be
Echinacea purpurea Root Extract 4% . 113 mg ** taken regularly for long-
term support of immune
Astragalus Root Extract 10:1................ 150 mg ** system. Increase daily water
**Daily Value not established intake when taking Jobelyn
products.
E
ven if these particular condition-specific formulas are not of interest,
two of them are perfect for general health and wellness. The Heart
Health and Joint Health Formulas contain the most versatile herbal
blends that are beneficial to anyone, no matter what their health goals are.
If you’re interested in simply experiencing the effects of Sorghum bicolor
leaf extract, these two products are a great place to start.
Jobelyn products are the most trusted source of traditional Sorghum bicolor
leaf extract worldwide. In fact, it was specifically the Jobelyn sorghum
leaf extract that was used as the ingredient source for most of the studies
cited in this booklet. Whenever you’re shopping for an herbal product,
that’s one of the most important qualities to look for—a company that
has had its own ingredient subjected to scientific studies.
Regardless of the specific Jobelyn product you choose, you can rest assured
that it will be safe13 and effective. Within three to four weeks, you’ll be
surprised at the health-changing results. Sorghum bicolor leaf extract has
been a trusted remedy for centuries in traditional African medicine, and
now it’s finally available to the rest of the world. May you discover
increased wellness and renewed energy as you provide your body with
the antioxidant and natural anti-inflammatory support it needs!
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Endnotes
1–Vivacell Biotechnology GMBH (2005) “Anti-Inflammatory effects of
Jobelyn” (Report: Phase I Results).
2–Bensen E, MD-3-3-096-1083. MD Biosciences, Inc., USA, (2008).
“1-16 Evaluation of Four Compounds in an In vitro LPS-Stimulated
Human PBMC Model”
(Report: Indirect Cox Activity Assay).
3–Okochi VI, Okpuzor J, Okubena MO, Awoyemi AK (2003). “The
influence of African Herbal Formula on the haematological parameters
of trypanosome infected rats.” African Journal of Biotechnology 2(9): 312-316.
4–Obinwano C., M.D. (1998). Independent preliminary clinical research.
Golden Heart Medical Centre; Lagos, Nigeria. Supplementation with
Sorghum bicolor leaf sheath extract connected to significant improvements
in cases of anemia resulting from severe malaria, sickle cell anemia, enteric
fever, helminthiasis, and acute lymphoblastic leukemia, and one case of
severe arthritis.
5–Erah PO, Asonye CC, Okhamafe AO (2003). “Response of
Trypanosoma brucei brucei-induced anaemia to a commercial herbal
preparation.” African Journal of Biotechnology. 2(9): 307-311.
6–Ogwumike OO (2002).“Hemopoietic effect of aqueous extract of the
leaf sheath of Sorghum bicolor in albino rats.” African Journal of Biomedical
Research. 5(1-2): 69-71.
7–Okochi V, Okpuzor J, Alli LA (2003). “Comparison of an African
herbal formula with commercially available haematinics.” African Journal
of Biotechnology. 2(8): 237-240.
8–Abia-Okon, DA, M.D. (2008). Independent preliminary clinical
research. Lindabel Medical Centre; Lagos, Nigeria. Significant
improvements in Hb and PCV values in 90% of 113 anemic subjects
supplemented with 250 mg of Sorghum bicolor leaf sheath extract two
times daily for 7 days.
9–Platt, OS (2000). “Sickle cell anemia as an inflammatory disease.” The
Journal of Clinical Investigation. 106(8): 337–338.
11 ,
10–Singh RB, Niaz MA, Agarwal P, Begom R, Rastogi SS (1995).
“Effect of antioxidant-rich foods on plasma ascorbic acid, cardiac enzyme,
and lipid peroxide levels in patients hospitalized with acute myocardial
infarction.” Journal of the American Dietetic Association. 95(7): 775-780.
Where to get Jobelyn

11–Kumar CA, Das UN (2000). “Lipid peroxide, antioxidants and nitric

oxide in patients with preeclampsia and essential hypertension.” Medical
Science Monitor. 6(5): 901-907.

12–Ayuba G, Col. (2003). Independent preliminary clinical research.

Military Hospital, Lagos, Nigeria. Findings: Supplementation with extract
of Sorghum bicolor leaf sheath found to increase CD4 cell counts in HIV
positive subjects when used alone or in combination with ARDs.

13–Eniojukan JF,Aina BA (2009).“Toxicological Profiles of Commercial

Herbal Preparation, Jobelyn®.” International Journal of Health Research.
2(4): 369-374.

Health Forever – Jobelyn Products

Manufactured for distribution in USA by:

Hains Herbal Product, LLC
1.888.328.5279
www.health-forever.com
info@ health-forever.com

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About the Author

W ith a medical career that has

spanned Europe and Africa,
David Abia-Okon, MD is now
the Medical Director at Lindabel
Medical Centre in Lagos, Nigeria.
In his own practice, he specializes
in general and vascular surgery. He
is also intrigued by natural products
and enjoys developing treatment programs that utilize the
best of both mainstream medicine and alternative health.
Dr. Abia-Okon had heard of Sorghum bicolor folk remedies,
but it wasn’t until he had some professional experience
with the extract that he became convinced of its incredible
antioxidant power and protective effects. Colleagues in
Nigeria had conducted studies on a standardized extract
based on the folk remedy and found it helpful for sickle cell
anemia and immune system compromised patients. This
caught Dr. Abia-Okon’s attention, and he began studying
the extract in his own practice. Conducting preliminary
clinical research and reviewing other published studies, he
became convinced of the extract’s power to spark incredible
improvement in a wide variety of health conditions where
inflammation and oxidation are chief aggravating factors.
Dr. Abia-Okon continues to practice in Nigeria, dedicated
to discovering and implementing the best health care
approaches for each individual patient. He is a member of
the Nigerian Medical Association and the Association of
General and Private Medical Practitioners of Nigeria.