SYRINGE PUMP

SMARTFUSION
CSP-100NE/CSP-100NS

OPERATION MANUAL

NIPRO CORPORATION

0905N
 General
1. The device should be used only by skilled and experienced professionals.

2. When installing the device, make sure of the following points.

1) Install in a dry place where the device can not be splashed with water.
2) Install in a place where the device can not be affected with atmospheric pressure, temperature, humidity,
ventilation, sunlight, dust, salt, the air containing sulfur, etc., and others.
3) Always make sure the device is placed stably. Avoid inclined plane, vibration, and impact (also during
transfer).
4) Do not install the device where any chemical agents are kept or any gases are produced.
5) Note the frequency, voltage, and allowable current (or power consumption) of the power source.
6) Ground the device properly.

3. Prior to use the device, make sure of the following points.

1) Check the switch contacts, polarity, dial setting, meter, etc. and make sure the device functions accurately.
2) Check that the device is securely grounded.
3) Check that all the cords are connected correctly and firmly.
4) Be cautious of using other devices concomitantly as accurate diagnosis may be impeded or hazard may be
induced.
5) Recheck the external circuit that is connected directly to the patient.

4. While using the device, make sure of the following points.

1) Always watch out for any abnormality in the device system and the patient.
2) When any abnormality is found with the device and the patient, take appropriate measure such as pressing
the [Stop] switch after making sure that there is no hazard to patient by halting the device operation.
3) Prevent the patient from touching the device.

5. After each use of the device, make sure of the following points.
1) Turn off the device after putting the operational switch and dial, etc. back to the initial state using the specified
procedures.
2) When removing the cord, do not apply excessive force. Always hold the plug to remove the cord.
3) When storing the device, make sure of the following points.
[1] Store the device in a dry place where it can not be splashed with water.
[2] Store the device in a place where it can not be affected with atmospheric pressure, temperature, humidity,
ventilation, sunlight, dust, the air containing salt, sulfur, etc., and others.
[3] Always make sure the device is placed stably. Avoid inclined plane, vibration, and impact (also during
transfer).
[4] Do not store the device where any chemical agents are kept or any gases are produced.
4) Clean the accessories, cords, and cables after each use and keep them organized in one place.
5) Always clean the device after each use so that it can be readily used next time.

6. When the device malfunctions, do not try to repair it. Put a proper notice on the device and ask the service
personnel for repair.

7. Do not modify the device.

8. Maintenance and inspection

1) Periodically check the device and its parts.
2) When using the device first time after it has not been used for a long time, check that the device functions
normally and safely prior to use.

2
Contents
Contents . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3

SAFETY WARNINGS/CAUTIONS . . . . . . . . . . . 4
Warning . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4
Contraindication / Prohibition . . . . . . . . . . . . . 4
Precautions for use in relation
to the operational procedures . . . . . . . . . . . . . 5
Precautions for use . . . . . . . . . . . . . . . . . . . . . 5
Product Overview . . . . . . . . . . . . . . . . . . . . . . . 6
Product Overview . . . . . . . . . . . . . . . . . . . . . . 6
Features . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6
Name of each part/Configuration . . . . . . . . . . 7
External View of the Main Body . . . . . . . . . . . . 7
Operation Panel . . . . . . . . . . . . . . . . . . . . . . . . 7
Accessories . . . . . . . . . . . . . . . . . . . . . . . . . . . 8
Applications (optional) . . . . . . . . . . . . . . . . . . . 8
Operating Procedure. . . . . . . . . . . . . . . . . . . . . 9
1.Preparation . . . . . . . . . . . . . . . . . . . . . . . . . 9
2.Turning the Power On . . . . . . . . . . . . . . . . 9
3.Opening the “Slider guarding bar” . . . . . . 11
4.Loading the syringe . . . . . . . . . . . . . . . . . 11
5.Setting the flow rate . . . . . . . . . . . . . . . . . 13
6.Priming . . . . . . . . . . . . . . . . . . . . . . . . . . . 13
7.Clearing the Total Infusion Volume . . . . . 14
8.Venipuncture . . . . . . . . . . . . . . . . . . . . . . 14
9.Starting Infusion . . . . . . . . . . . . . . . . . . . . 15
10.For displaying the total
infusion volume during infusion . . . . . . . . 15
11.Changing the flow rate during infusion . . 16
12.Completing the infusion . . . . . . . . . . . . . . 16
13.Turning off the power . . . . . . . . . . . . . . . . 17
If the alarm sounds during infusion . . . . . . . . 18
Other operational procedures . . . . . . . . . . . . 19
Replacing the syringe to continue infusion . . 19
Operating on the internal battery . . . . . . . . . 19
Method of switching modes . . . . . . . . . . . . . 20
Switching the alarm volume . . . . . . . . . . . . . . 20
Change the occlusion pressure
detection level . . . . . . . . . . . . . . . . . . . . . . . . 21
Changing the nearly-empty alarm timing . . . 22
Setting date and time . . . . . . . . . . . . . . . . . . . 23
Displaying the history . . . . . . . . . . . . . . . . . . 24
Indicating the time
for periodic maintenance . . . . . . . . . . . . . . . . 25
Displaying the total operation time . . . . . . . . 26
Setting of maximum flow rate. . . . . . . . . . . . . 26
Changing the syringe brand . . . . . . . . . . . . . 26
Setting of serial communication . . . . . . . . . . 26
After Operation . . . . . . . . . . . . . . . . . . . . . . . . 27
Cleaning. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27
How to Deal with Alarm and Trouble . . . . . . . 28
Error Code list . . . . . . . . . . . . . . . . . . . . . . . . 30
Maintenance and inspection . . . . . . . . . . . . . 36

Specifications . . . . . . . . . . . . . . . . . . . . . . . . . 36

3
SAFETY WARNINGS/CAUTIONS
For safe operation, be sure to comply with the following warnings and cautions.
The following labels appear at places in this manual to indicate the magnitude of risk and
damage that may occur in the event that these warnings and precautions are not observed.
This label preceding precautions indicates that
Warning there will be a possible risk of death or serious
personal injury if the precautions in the box are
not observed.
This label preceding precautions indicates that
Caution there will be a possible risk of personal injury or
property damage if the precautions in the box
are not observed.
Warnings
1. Confirm that the flange of the syringe barrel is set in the slit firmly and the flange of the syringe
plunger is held securely by the syringe clamp.
(If the above warnings are not observed, not only the various alarm functions but also the flow rate
accuracy can not be guaranteed.)
2. When starting infusion, confirm infusing state and the site of venipuncture. Do not rely on the alarm
function only. Regularly confirm that the remaining amount in the syringe and the set flow rate are
consistent.
3. When the infusion line is occluded, take appropriate corrective actions such as clamping the
infusion line to prevent over infusion
4. Use this pump at a place sufficiently distant from high-frequency wave generating devices such as
medical electric knife, a mobile telephone, radio apparatus to avoid malfunction caused by radio-
wave interference. Connect the pump to a power outlet different from these devices and ground the
pump appropriately.
5. If the pump is dropped onto the floor, or given an impact, immediately stop using it.
(The pump needs service even if it appears normal externally and no abnormal operations are
observed as the inside may be damaged. Contact our sales representative in charge.

Contraindication / Prohibition
1. This pump is specially designed for disposable syringes. Therefore, avoid using any syringe once used.
2. Use only the specified syringes for the pump.
(If a syringe other than the specified is used, flow rate accuracy and alarm functions can not be
guaranteed. Moreover, a medical accident may result.)
3. Do not use the pump in the controlled area of radiological equipment/MRI and in the hyperbaric
oxygen therapy room. Do not use the pump placed outside the hyperbaric oxygen therapy room but
with the infusion line put inside.
(This pump has not been designed with the use in these environments taken into account. Using this
pump under these environments may cause the pump to malfunction, break, or induce explosion)
4. Do not use this pump in a flammable environment.
(The pump may induce fire or explosion.)
5. Do not connect this pump to a circuit in which an excessive negative pressure may arise.
(The syringe plunger may come off the slider of the pump causing the solution to be infused rapidly.)
6. Do not use this pump concomitantly with gravity infusion.
(The pump may not operate according to the specifications: Air bubbles may be formed at the
connection point of the infusion lines downstream to the pump or an alarm state downstream to the
connection site can not be detected.)

4
 SAFETY WARNINGS/CAUTIONS
Precautions for use in relation to the operational procedures
1. Be sure to prime the line before starting the infusion.
(This expels the air out of the tube, eliminates the gap between the flange of the syringe barrel and
the slit, and starts infusion as soon as the [Start] switch is pressed.)
2. Do not remove the syringe without closing the infusion line.
3. Be sure to connect an external device that operates normally when using the external
communication function of the pump. The pump should not be infusing while it is connected to
an external device.
4. Do not use this product and other infusion systems at the same time.
(If other infusion systems are used concomitantly, the pump may not operate according to the
specifications.)
5. When using the pump for microinfusion, be careful of the kink in the infusion line.
(The time to occlusion detection takes longer as the flow rate is set lower. The solution may not be
infused for a long time if kink occurs.)
6. The solution should have reached the room temperature prior to infusion.
(Infusing cold solution may raise the friction resistance of the syringe plunger causing the occlusion
alarm to occur frequently.)
7. When using a prefilled syringe, adjust the setting to the prefilled syringe used.
(The pump may not operate according to the specifications if a prefilled syringe is used without the
setting changed.)
8. If any abnormality is found, contact our sales representative in charge.

Precautions for use

1. Prior to using the pump at the first time after purchase, connect it to AC mains and charge it at least 15 hours.
2. Check that the buzzer sounds and all the lamps blink when the [Power] switch is turned on.
3. If “ ”~“ ” appears on the [Flow rate/Total Infusion Volume] display and the alarm
sounds while self-check is being performed at the power-on or during infusion, the system may be
malfunctioning. Stop using the pump immediately.
4. Install the pump in a place where there is no possibility of the solution splashed onto the AC mains
connector, which may cause short-circuiting.
5. The difference in height between the pump and the patient should be minimized.
6. The internal battery self-discharges even if not used. Charge the internal battery at least 15 hours
when using the pump at first time after it has not been used for a long time.
(It is recommended that the internal battery should be discharged and charged once in a month.)
7. Before using this pump concurrently with an electric cautery, note the following precautions.
1) The extent of high-frequency noise varies for each model of electric cautery. Bigger noises come
from older type of electric cautery (Vacuum tube and gap system). Such model of electric
cautery should be avoided.
2) Provide the sufficient distance between the cord (cautery holder, cautery cord and cord of
counter electrode) or main unit of electric cautery and this pump.
3) Plug the electric cautery and this pump to different power outlets.
8. Turn off the power of this pump and store the slider after each use.
9. Before cleaning the pump, note the following precautions.
1) Be sure to turn off the power, and unplug the power cord.
2) Do not immerse and clean the pump in the water or other solutions.
(Ingress of solution into the pump may cause short-circuit of the electric circuit.)
3) Do not autoclave or EOG sterilize the pump.
4) Do not use alcohol, thinner or any other organic solvent.

5
Product Overview
Product Overview

Nipro Smartfusion is a medical syringe pump designed for precise continuous infusion of
vasodilatation and vasopressor drugs, analgesics, anti-cancer drugs, anti-coagulants, nutrition for
premature and new born babies, various hormone drugs, and the like with microcomputer control.
The pump operates on AC 100V – 240V mains or internal battery and incorporates a sensor that
detects the size of the syringe loaded. The infusion speed is adjusted and purge is performed as the
following: the rotation speed of the stepping motor is pulse-controlled, then, the rotating motion is
converted into the linear motion to move the slider that pushes the syringe plunger. Abnormality
detection sensors such as syringe loading in-completion, occlusion, and nearly-empty detection
sensors are incorporated as safety devices.

Features

• Small and compact. Easy for carrying and installing multi pumps. Can be stored in a small space.
• Compatible with 10, 20, 30, and 50(60) mL disposable syringes.
• Constantly watches for the syringe plunger disengagement.
• The occlusion detection pressure can be switched to three levels (L, M, and H).
• Flow rate can be set to a desired value in the wide range (0.1-300.0 mL/h).
• Can be operated on either of the three power sources: AC mains, internal battery or Pump Uniter.
• Can be continuously operated on internal battery for approximately 2 hours.
(New internal battery, ambient temperature of 25°C, after charged 15 hours with the power off, flow
rate of 5.0 mL/h)
• Four levels of lamp indication show the amount and remaining charge of the internal battery.
• Disposable syringes from Nipro, Terumo, JMS, and TOP and other brands can be used by changing
the default setting.
• Large pilot lamp with good visibility is incorporated.
• The set flow rate is shown in large figures. The figures below the decimal points are shown smaller.
This prevents the flow rate setting error. The figures below the decimal points are shown smaller and
the color is different.
• The upper part of the operation panel is allocated to the display and the lower part to the operational
section for ease of use.
• The syringe clamp is easy to use: the user just need to pull it up.
• The history data can be exported to PC using the external communication function.
• The alarm sound volume can be switched to three levels.
• The timing for nearly-empty alarm can be switched to three levels.

6
Name of each part/Configuration
External View of the Main Body

[Pilot] Lamp
Syringe Clamp
Slider
Slit
Slider
Guarding Bar

Computer Interface
Connector

Operation Panel
AC-power inlet

Operation panel
13 15 1617181920
10 11 12 21 22 2324
14

1 2 3 4 5 6 7 8 9
1. [Power] Switch 13. [mL/h] Lamp
Press to turn on or off the power Illuminates when the [Flow Rate/Total Infusion Volume] display
2. [Function] Switch shows flow rate
Press to indicate the size of the syringe loaded or to make setting 14. [mL] Lamp
in various modes. Illuminates when the [Flow Rate/Total Infusion Volume] display
3. [Shift ] Switch shows total infusion volume or syringe size
Press to alternate between flow rate and total infusion volume 15. [Flow Rate Setting] Mode Lamp
4. [Flow rate setting] Switches Illuminates when the [Flow Rate Setting] Switches are activated
Press to set the numerical value such as flow rate. Pressing the up 16. [Purge] Mode Lamp
switch( ) increases the value and pressing the down switch( ) Illuminates during purge
decreases the value. 17. [Infusing] Mode Lamp
5. [Clear] Switch Illuminates during infusion
Press to clear the total infusion volume 18. [Stop] Mode Lamp
6. [Purge] Switch Illuminates when the infusion is stopped
The infusion fluid is being purged while this switch is kept pressed. 19. [Internal battery Indication] Lamp(s)
7. [Start] Switch Blink(s) when the pump is powered by the internal battery. One to
Press to start the infusion three green lamp(s) or one red lamp blink(s) depending on the
8. [Stop] Switch residual amount of the internal battery
Press to stop the infusion 20. [AC Connect] Lamp
9. [Mute] Switch Illuminates when the pump is connected to AC mains
Press to mute the alarm sound 21. [Nearly Empty] Alarm Lamp
10. [Flow Rate] Lamp Illuminates when the nearly empty alarm occurs
Illuminates when the [Flow Rate/Total Infusion Volume] display 22. [Reminder] Alarm Lamp
shows flow rate Illuminates when operation reminder alarm occurs
11. [Total Infusion Volume] Lamp 23. [Occlusion Pressure] Alarm Lamp
Illuminates when the [Flow Rate/Total Infusion Volume] display Illuminates when occlusion alarm occurs
shows the total infusion volume 24. [Syringe Load In-completion] Alarm Lamp
12. [Flow Rate/Total Infusion Volume] Display Illuminates when the syringe load in-completion alarm occurs
Shows flow rate, total infusion volume, syringe size, occlusion
pressure detection level, syringe manufacturer, alarm sound
volume, date and time, history, and error code

7
Name of each part/Configuration
Accessories

AC Power Cord Pole Clamp Operation Manual

Applications (optional)

Pump Uniter PC Access Communication Cable

PU3-200NC,NE,NS SPS-100
The DC power is supplied to each pump Necessary to export the history by external
loaded and internal battery of the syringe communication function
pump is fully charged in approximately
15 hours.
The rack dedicated for syringe pumps is
attachable to the bed rail, etc.

8
Operational Procedures
1 Preparation

Before using this pump, read P. 2, “General” and

P. 4-5, “SAFETY WARNINGS/CAUTIONS.”

* When using this device for the first time,

connect it to the AC power source and charge
the internal battery at least 15 hours. Mounting Screw
Fixing to the infusion stand
Use the supplied pole clamp to fix the pump
securely to the infusion stand. To attach the
pump to the clamp, insert the mounting screw
Pole Clamp Infusion Stand
of the clamp into the screw hole on the bottom
of the syringe pump. (Fig. 1)
Fig. 1

Caution
Confirm the stability of the infusion stand.

1. Connect the furnished AC power cord to the AC

power inlet on the left side of the pump. (Fig. 2)
2. Plug the power cord into power outlet with a
proper grounding terminal.

* [AC Connect] lamp illuminates. (Connect to

the AC power source and charge it at least 15 AC Power Cord
hours when using it for the first time after
purchase or after it has not been used for a
long time.)
AC Power Inlet

Fig. 2
2 Turning the power on

1 Make sure that the syringe is not loaded. Then,

press the [Power] switch to turn the power on.
(Fig. 3)
The buzzer sounds and all the lamps blink as the
self-check function is performed.
2. Discontinue the use immediately if error
code[ ]~[ ] is displayed on the
[Flow Rate/Total Infusion Volume] display and
the alarm sounds. [Power] switch

* Refer to P. 31 “Maintenance and inspection”

for the error codes. Fig. 3

9
Operational Procedures
3. Confirm that the brand of the syringe to be used
corresponds to the setting in the pump.

* [Infusion Volume]
] appears on the [Flow Rate/Total
display to indicate the
[Flow Rate/Total
Infusion Volume]
display
syringe brand setting in the pump (about two
seconds). (Fig. 4)
( [*] is a number between 1-15. [__] are
blanks.)

Fig. 4

indication Manufacturer or type indication Manufacturer or type indication Manufacturer or type

NIPRO(JAPAN) 10-20-30-50mL Currently not in use. ROMSON 20-50mL
NIPRO(Overseas) 10-20-30-50mL TOP(JAPAN) 10-20-30-50mL ALSHIFA 10-20-50mL
TERUMO(JAPAN) 10-20-30-50mL Currently not in use. BBRAUN(JAPAN) 10-20-30-50mL
TREUMO(USA) 10-20-30-50mL Currently not in use. SHERWOOD(JAPAN) 60mL
JMS(JAPAN) 10-20-30-50mL HINDUSTAN 20-50mL B-D(JAPAN) 10-20-30-60mL

Warnings
· Confirm that the brand of the syringe to be used
corresponds to the setting in the pump. If they do not
match, alarm functions can not be guaranteed as
flow rate error exceeding the tolerance may arise.
· This pump is for disposable syringes only. Do not
reuse a syringe that has been used once.
· Stop operation immediately if any abnormality is detected.
Contact our sales representative in charge immediately.

4. The set occlusion detection level appears on the

[Flow Rate/Total Infusion Volume] display as
“ ” for about 2 seconds.
([*] is a number from 1-3.)

Indication Occlusion Pressure Detection Level

L : 40 ± 20 kPa

M : 70 ± 25 kPa

H : 100 ± 30 kPa
[Pilot] lamp

5. Confirm that [0.0] appears on the

[Flow Rate/Total Infusion Volume] display and [Syringe Load
[Flow Rate, [mL/h], [Flow Rate Setting] mode, [Flow Rate] lamp [mL/h] lamp In-completion] alarm
lamp
and [Stop] mode lamps illuminate. (Fig. 5)
6. Confirm that [Syringe Load In-completion] alarm
lamp illuminates and the [Pilot] Lamp illuminates
in red. (Fig. 5)

* This indicates that the syringe is not loaded. [Flow Rate Setting] mode lamp [Stop] mode lamp

Fig. 5

10
 Operational Procedures
3 Opening the “Slider guarding bar”

1. Open the “Slider guarding bar” and press in the

“Slider guarding bar lock.” (Fig. 6)
Slider
guarding
bar
Caution
If the “Guarding bar lock” is not pushed all the
way in and locked correctly, the flow rate
accuracy can not be guaranteed since the slider Slider guarding
bar Lock
is unprotected. Moreover, there is a possibility of
damage by the impact.
Fig. 6
4 Loading the syringe

1. Connect the syringe filled with solution and the

infusion line aseptically.

Caution
Lure lock type infusion line and syringe are
recommended.

2. While holding the slider lever, move the slider to

Slider lever
the right. (Fig. 7)

Fig. 7

3. Pull up the syringe clamp, and insert the flange Syringe clamp Flange of the syringe barrel
of the syringe barrel into the slit. (Fig. 8)

Warning
If the flange is not properly inserted into the slit,
flow rate accuracy and alarm functions can not
be guaranteed.

Slit

Fig. 8

11
Operational Procedures
4. Push down the “syringe clamp” silently to secure
the syringe.

* Figures indicating the syringe size appear on

the [Flow Rate/Total Infusion Volume] display
(about 2 seconds) and [mL] lamp illuminates.
Confirm that the indications match the syringe
to be used.

5. Hold the slider lever and move the slider forward

Slider
until it touches the flange of the syringe plunger
Flange of the syringe
lightly. (Fig. 9) plunger

Slider lever

Fig. 9

6. Release the slider lever to let the slider hook

Flange of the syringe plunger
hold the flange of the syringe plunger securely. slider lever
(Fig. 10)

* IfLoad
the syringe is loaded properly, the [Syringe
In-completion] alarm lamp will disappear.

Warning Slider hook

If the flange of syringe plunger is not securely

held with the slider hook, “siphoning (infusion by
gravity)” or “reverse flow” could result. Flow rate
accuracy can not be guaranteed. Fig. 10

7. While holding down the [Function] switch, the

loaded syringe size set in the pump appears on
the [Flow Rate/Total Infusion Volume] display.
(Fig. 11)

[Function] switch

Fig. 11

12
 Operational Procedures
5 Setting the flow rate

1. Confirm that the [Flow Rate] and [mL/h] lamps

are on and flow rate is on the [Flow Rate/Total
Infusion Volume] display. (Fig. 12) [Flow Rate] lamp [Flow Rate Setting]
[mL/h] lamp mode lamp
2. Confirm that the [Flow Rate Setting] mode lamp
is on, which indicates that the flow rate can be
entered. (Fig. 12)
3. Press the [Flow Rate Setting] switches and set
the flow rate per an hour (mL/h). (Fig. 12)
* Pressing the up switch ( ) increases the value
and pressing the down switch ( ) decreases
[Flow Rate Setting]
switches
the value. Set the figure for each digit. Fig. 12

* The flow rate can be set to any desired value in

the range of 0.1-300.0 (mL/h) in 0.1 (mL/h) step.
6 Priming

Warning
Perform this procedure before inserting I.V.
catheter into the patent.

Caution
The priming volume is added to the Total
Infusion Volume

1. Confirm that the [Syringe load In-completion] alarm

lamp is off and the syringe is loaded properly.
Confirm that no alarm is generated.

* Ifswitch
any alarm is generated, press the [Mute]
to cancel the alarm. Then, eliminate
the cause of the alarm.
[Purge] mode lamp
(Refer to P. 28, “How to deal with alarm and
trouble.”)
2. Pressing the [Purge] switch starts the priming [Purge] switch
and the total infusion volume during the priming
is shown on the [Flow Rate/Total Infusion Fig. 13
Volume] display. (Fig. 13)

* Check that the buzzer sounds intermittently,

the [Pilot] lamp blinks rapidly in green, and the
Flange of the syringe barrel
[Purge] mode lamp illuminates.

* The priming volume is added to the Total

Infusion Volume

Warning
Prime the line before starting infusion. Unless Slit
the line is primed, the air stays in the tube; the
gap exists between the flange of the syringe
barrel and the slit, which cause the delay of
infusion when the [Start] switch is pressed. (Fig. 14) Fig. 14

13
Operational Procedures
7 Clearing the Total Infusion Volume

To clear the volume added to the total infusion

volume during priming, perform the following [Total Infusion Volume] lamp

procedures. If you do not need to clear this volume,

proceed to P. 14, “8.Venipuncture.”

1. Press the [Shift] switch and confirm that total

infusion volume appears on the [Flow Rate/Total
Infusion Volume] display. (Fig. 15)

* [Total Infusion Volume] and [mL] lamp

illuminate. [Shift] switch [mL] lamp

Fig. 15

2. While the total infusion volume is on the display

(about 15 seconds), keep holding down the
[Clear] switch (about 1 second) to clear the total
infusion volume. (Fig. 16)

* Confirm that [0.0] appears on the [Flow Rate/

Total Infusion Volume] display.

[Clear] switch

Fig. 16
8 Venipuncture

1. Confirm that the pump is stopped. Then,

puncture the I.V. catheter into the patient. (Fig. 17)
I.V. catheter

Warning
Alarm system is not provided for detecting the
I.V. catheter coming out of the vein resulting in
extravenous infusion. Therefore, confirm the
point of venipuncture periodically.

Fig. 17

14
 Operational Procedures
9 Starting the infusion

1. Confirm that the flow rate is set, the syringe is

loaded securely, and the alarm is not generated. [Infusing] mode lamp

* Ifswitch
any alarm is generated, press the [Mute]
to cancel the alarm. Then, eliminate
the cause of the alarm.
(Refer to P. 28, “How to deal with alarm and
trouble.”)

[Start] switch
2. Press the [Start] switch to commence the
infusion. (Fig. 18) Fig. 18

* Confirm that the [Pilot] lamp blinks in green

and only the [Infusing] mode lamp illuminates.

* The flow rate can not be changed during

infusion. Stop the infusion to change the flow
rate setting.

3. When you need a purge during infusion, press

the [Start] and [Purge] switches at the same
time. The purge starts and the total infusion [Purge] mode lamp [Infusion] mode lamp

volume during purge is shown on the

[Flow Rate/Total Infusion Volume] display.
(Fig. 19)

* Confirm that the buzzer sounds intermittently,

the [Pilot] lamp blinks rapidly in green, and the
[Start] switch
[Purge] mode lamp illuminates.
[Purge] switch

Fig. 19

10 For displaying the total infusion volume during infusion

1. Pressing the [Shift] switch alternates the display

between the flow rate and the total infusion
volume. (Fig. 20)

[Shift] switch

Fig. 20

15
Operational Procedures
11 Changing the flow rate during infusion

1. Press the [Stop] switch to stop the infusion.

(Fig. 21)
[Flow Rate Setting] mode lamp [Stop] mode lamp

* Confirm that the [Pilot] lamp turns off and the

[Flow Rate Setting] and [Stop] mode lamps
illuminate.

[Stop] switch

Fig. 21

2. When changing the flow rate, press the [Flow

Rate Setting] switches to enter the desired value
while the pump is stopped. (Refer to P. 13, [Flow Rate] lamp [Flow Rate Setting]
“5. Setting the flow rate.”) (Fig. 22) [mL/h] lamp mode lamp

[Flow Rate Setting]

switches
Fig. 22
12 Completing the infusion

1. Press the [Stop] switch to stop the infusion.

(Fig. 23)
[Flow Rate Setting] mode lamp [Stop] mode lamp

* Confirm that the [Pilot] lamp turns off and the

[Flow Rate Setting] and [Stop] mode lamps
illuminate.
2. Close the infusion line.

[Stop] switch

Fig. 23

16
 Operational Procedures
13 Turning off the power

1. Keep pressing down the [Power] switch (about 4

seconds) to turn off the power. The buzzer
sounds 3 times every 1 second while the switch
is kept pressed until the power is turned off.
(Fig. 24)

[Power] switch

Fig. 24

2. Hold the slider lever and move the slider to the

right. (Fig. 25) Slider

Caution
Do not remove the syringe before moving the
slider to the right.

Slider Lever

Fig. 25

3. Pull up the syringe clamp and remove the Syringe Clamp

syringe. (Fig. 26)
Syringe

Warning
Do not remove the syringe before closing the
infusion line.

Fig. 26

Caution
• This pump has not been designed to detect any abnormality in infusion such as “over-infusion” or “under
infusion.” During infusion, do not rely solely on the alarm functions and regularly check that the remaining
amount in the syringe and the set flow rate are consistent.
• Confirm that the flange of the syringe barrel is set properly in the slit and that the flange of the syringe
plunger is secured firmly by the slider hook. If the flanges are dislocated, gravity infusion or reverse flow may
occur. Also, it is recommended to minimize the difference in height between the pump and the patient
connection site.
• When the infusion line is occluded, the internal line pressure is increased. Eliminate the cause of occlusion
only after appropriate measures have been taken to prevent over-infusion such as clamping the infusion line.

17
Operational Procedures
If the alarm sounds during infusion

If the [Pilot] lamp illuminates in red and the

[Syringe Load In-completion] alarm lamp turns [Pilot] lamp
on with the alarm sound, the syringe is not
loaded properly.
The infusion has been stopped automatically for
safety. Press the [Mute] switch to cancel the alarm
sound. Load the syringe properly referring to P. 11,
“4. Loading the syringe.” (Fig. 27)

[Syringe Load In-completion] alarm lamp

Fig. 27

If the [Nearly Empty] alarm lamp illuminates and

the alarm sounds intermittently, the remaining
solution amount in the syringe has fallen low.
(Fig. 28) Press the [Mute] switch to cancel the alarm
sound. If you want to continue the infusion, replace
the syringe referring to P. 19, “Replacing the syringe
to continue infusion.”

[Nearly Empty] alarm lamp

Fig. 28

If the [Pilot] lamp illuminates in red and the

[Nearly Empty] alarm lamp turns on with the [Pilot] lamp
alarm sound, the syringe has been emptied.
(Fig. 29) Press the [Mute] switch to cancel the alarm
sound. If you want to continue the infusion, replace
the syringe referring to P. 19, “Replacing the syringe
to continue infusion.”

[Nearly Empty] alarm lamp

Fig. 29

If the [Pilot] lamp illuminates in red and the

[Occlusion] alarm lamp turns on with the alarm [Pilot] lamp
sound, the infusion line is occluded and the line
pressure has exceeded the occlusion detection
pressure.
(Fig. 30) The infusion has been stopped
automatically for safety. Press the [Mute] switch to
cancel the alarm sound. Since the infusion line
pressure is increased, close the line to prevent over-
infusion at the release of occlusion. Hold the slider
lever to release the occlusion. [Occlusion pressure] alarm lamp

Fig. 30

18
Other operational procedures
Replacing the syringe to continue infusion
1. Press the [Stop] switch and close the infusion line. (Fig. 31)
2. After confirming that the brand of the replacing syringe
corresponds to the setting in the pump, load the syringe.
3. After switching the infusion line using a three way
stopcock or equivalent to prevent the solution from
being delivered to the patient, perform priming
referring to P. 13, “6. Priming.”

Warning
[Start] switch
Prime the line before starting infusion. Unless the line is
primed, the air stays in the tube; the gap exists between
Fig. 31
the flange of the syringe barrel and the slit, which cause
the delay of infusion when the [Start] switch is pressed.

4. Clear the total infusion volume if necessary. (Refer

to P. 14, “7. Clearing the total infusion volume.”)
5. Open the infusion line and press the [Start] switch
to commence infusion.
Operating on the internal battery
When the supply of AC power is interrupted or the AC
voltage is decreased during infusion, the pump will be
automatically switched to internal battery operation.
The internal battery powers the pump for about 2
hours (in case of a new internal battery, ambient
temperature of 25°C, after charge of at least 15 hours
with the power turned off, and flow rate of 5.0 mL/h)
*
During internal battery operation, [AC Connect]
lamp is off and the [Internal battery Indication]
lamp illuminates. Check whether the pump is
on internal battery or not by watching these
lamps. (Fig. 32)
[Battery Indication] lamps
Caution
Fig. 32
• Prior to using the pump at the first time after purchase,
connect it to AC mains and charge it at least 15 hours.
• The internal battery self-discharges even if not
used. Charge the internal battery at least 15
hours when using the pump at the first time after
it has not been used for a long time. Discharge 3 green lamps
the internal battery fully once a month. Approx. 90 minutes or more
• When the internal battery voltage has decreased 2 green lamps
and the remaining time on internal battery has Approx. 60 minutes or more
fallen below approx. 30 minutes or so, the buzzer 1 green lamp
sounds every approx. 10 minutes. Connect the Approx. 30 minutes or more
pump to the AC mains immediately. If the pump is 1 red lamp
used continuously without being connected to the Approx. 30 minutes or less
AC outlet, it will automatically shut down.
• When the actual remaining time on internal battery New battery, ambient temperature of 25°C, after charge of at least 15 hours
has become shorter than the time indicated by the with the power turned off, flow rate of 5.0 mL/h
[Internal battery Indication] lamps as shown in the Fig. 33
box on the right, the internal battery is deteriorating.
Ask for internal battery replacement immediately or
keep in mind that the internal battery needs
replacement soon. If the ambient temperature is low,
the remaining time indicated by the [Internal battery
Indication] lamps tends to be longer than the actual
remaining time.
The approximate remaining times indicated by the [Internal
battery Indication] lamps are shown in the right. (Fig. 33)
*
Confirm the [Internal battery Indication] lamps
with the AC mains connected to the pump.
19
Other operational procedures
Method of switching modes

Switch the mode to change the alarm volume,

occlusion detection pressure level, or nearly empty
alarm timing, to switch the syringe setting to prefilled,
to set the date and time, or to display the history.

1. Confirm that the infusion is stopped

* The green [Pilot] lamp is off, and the [Stop]

mode lamp illuminates.
2. Press and hold the [Function] switch and [Shift] switch [Function] [Shift] switch
switch
at the same time until the buzzer sounds. (Fig. 34)
3. Confirm that [ ] appears on the [Flow Fig. 34
Rate/Total Infusion Volume] display, which
indicates that the pump is in the alarm volume
switching mode.
4. Each time you press the [Shift] switch, the mode
changes in order of “Switching alarm volume”
(display: ), “Switching occlusion
detection pressure level” (display: ),
“Switching Nearly empty alarm timing”
(display: ), “Switching the syringe
setting to prefilled” (display: ), “Setting
date and time” (display: ), and “Displaying
History” (display: ) mode. (Fig. 35)
[Shift] switch
5. Pressing the [Stop] switch returns the mode to
the default. Fig. 35

Switching the alarm volume

The alarm volume can be switched to 3 levels.

1. Change the mode to “Switching alarm volume” [Flow Rate Setting]
mode lamp
referring to P. 20, “Method of switching the mode.”

* Confirm that [ ] appears on the [Flow

Rate/Total Infusion Volume] display and the
[Flow Rate Setting] mode lamp illuminates. [*]
is a number from 1-3. [ _ ] are blanks. (Fig. 36)
2. Change the setting to the desired level using the
first digit of decimal point switches of the [Start] switch
[Flow Rate Setting]
[Flow Rate Setting] switches. switches

3. Press and hold the [Start] switch until the buzzer Fig. 36
sounds for confirmation and the set value is saved.
4. The alarm volume levels are displayed as the following.

Indication volume

bU_1 Small

bU_2 Medium

bU_3 Large

20
* Operational and purge sound levels can not be changed.
 Other operational procedures
Change the occlusion pressure detection level

Occlusion detection pressure can be switched to 3

levels. [Flow Rate Setting]
mode lamp
1. Change the mode to “Switching occlusion
detection pressure” referring to P. 20, “Method of
switching the mode.”

* Confirm that [ ] appears on the [Flow

Rate/Total Infusion Volume] display and the
[Flow Rate Setting] mode lamp illuminates.
([*] is a number from 1-3.) (Fig. 37)
[Flow Rate Setting] [Start] switch
switches

2. Change the setting to the desired level using the Fig. 37

first digit of decimal point switches of the
[Flow Rate Setting] switches. (Fig. 37)
3. Press and hold the [Start] switch until the buzzer
sounds for confirmation and the set value is
saved. (Fig. 37)
4. The Occlusion detection pressure levels are
displayed as the following.

Indication Occlusion Pressure Detection Level

L : 40 ± 20 kPa

M : 70 ± 25 kPa

H : 100 ± 30 kPa

Caution
If the [Occlusion] alarm is generated frequently,
first, check the infusion line and the syringe,
then, change the flow rate setting without
switching the occlusion detection pressure level.
If the alarm still recurs frequently, switch the
occlusion detection pressure to a higher level.

21
Other operational procedures
Changing the nearly-empty alarm timing
Nearly-empty alarm timing can be switched to 3
levels.
[Flow Rate Setting]
1. Change the mode to “Switching Nearly-empty mode lamp
alarm timing” referring to P. 20, “Method of
switching the mode.”

* Confirm that [ ] appears on the [Flow

Rate/Total Infusion Volume] display and the
[Flow Rate Setting] mode lamp illuminates.
([*] is a number from 1-3.) (Fig. 38)
2. Change the setting to the desired level using the
[Flow Rate Setting] [Start] switch
first digit switches of the [Flow Rate Setting]
switches
switches. (Fig. 38)
Fig. 38
3. Press and hold the [Start] switch until the buzzer
sounds for confirmation and the set value is
saved. (Fig. 38)
4. The Nearly-empty alarm timings are displayed as
the following.

Display Nearly-empty alarm timing

F : Approx. 6 minutes before
drug termination
M : Approx. 30 minutes before
drug termination
S : Approx. 60 minutes before
drug termination

The alarm will be generated at the minimum

remaining volume if the remaining volume for
generating the alarm corresponding to the set
nearly-empty alarm timing is lower than the minimum
remaining volume specified below.

Syringe Size Minimum remaining volume

10mL Approx. 0.6mL

20mL Approx. 0.9mL

30mL Approx. 1.2mL

50mL Approx. 1.5mL

Example ) Empty alarm Nearly-empty alarm set to

approx. 30 minutes before the
In case of 50 mL syringe, Nearly-empty alarm Almost Empty alarm (remaining
drug termination (remaining
amount: approx. 1.5 mL)
amount: approx. 5.0 mL)
timing: M, and Flow rate: 10.0 mL/h
Nearly-empty alarm will be generated when the
remaining amount is approx. 5.0 mL (Fig. 39)
Fig. 39
Example ) Empty alarm
In case of 50 mL syringe, Nearly-empty alarm Almost Empty alarm (remaining
amount: approx. 1.5 mL)
timing: M, and Flow rate: 2.0 mL/h
Nearly-empty alarm will not be generated when
the remaining amount is approx. 1.0 mL (Fig. 40)
Fig. 40
Caution
Almost-empty alarm is always generated. If you
need to continue the infusion, replace the
syringe referring to P. 19, “Replacing the syringe
to continue the infusion.”
22
 Other operational procedures
Setting date and time

1. Change the mode to “Setting date and time”

referring to P. 20, “Method of switching the
mode.”

* Confirm that [ ] appears on the [Flow

Rate/Total Infusion Volume] display for about
2 seconds and the display changes to
[ ] indicating the dominical year.
(Fig. 41)
2. Each time you press the [Start] switch, the
[Flow Rate Setting] [Start] switch
display changes in the order of “dominical year,” switches
“month and date,” and “time.” (Fig. 41) Fig. 41
For example ,
Dominical year of 2005 is shown as [ ]
October 20 is shown as [ ]
Five thirty in the afternoon is shown as
[ ]
3. Switch the display to the item you need to change.
Enter each digit using the corresponding
[Flow Rate Setting] switches. (Fig. 41)
4. The setting will be saved when you press the [Start]
switch to change the displayed item. (Fig. 41)

23
Other operational procedures
Displaying the history

Maximum 200 events of operational history such as

the date and time of infusion start and stop, purge,
alarm, error, and shutdown as well as the set flow
rate and type of the alarm generated can be stored
and displayed.

1. Change the mode to “Displaying history”

referring to P. 20, “Method of switching the
mode.”

* Confirm that history event number [

appears on the [Flow Rate/Total Infusion
]
[Flow Rate Setting] [Start] switch
switches
Volume] display. (Fig. 42)
Fig. 42
2. Press the [Flow Rate Setting] switch to display
the event that you want to refer to. (Fig. 42)
3. Each time you press the [Start] switch, [Flow
Rate/Total Infusion Volume] display changes in
the order of “month and date,” “time,”
“operational parameters,” and [ ]. While
the operational parameters are displayed on the
display, (a) lamp(s) illuminate(s) to indicate the
event occurred at that time. (Fig. 42)
4. “Operational parameters” displayed vary
depending on the event.

Event Indication section

Lamps [Flow Rate · Total Infusion Volume] display

Infusion start [Infusing] mode lamp illuminates Occlusion detection Flow rate Total infusion
Syringe Size pressure level
[Pilot] lamp illuminates in green volume
Infusion stop [Stop] mode lamp illuminates Occlusion detection Flow rate Total infusion
Syringe Size pressure level volume
[Pilot] lamp is off
Purge [Purge] mode lamp illuminates Occlusion detection Total infusion Volume
Syringe Size pressure level
[Pilot] lamp illuminates in green
Alarm An alarm lamp illuminates
[Pilot] lamp illuminates in red
Error [Pilot] lamp illuminates in red Error code

Power-on [ _ ] Remaining battery amount

Power-off [ _ ] Remaining battery amount

Operated on AC [_ _ ] Remaining battery amount

Operated on
internal battery [_ _ ] Remaining battery amount

Shutdown [_ _ ]

24
 Other operational procedures
History export method using the external communication function
1. Change the mode to “Displaying history” referring to P. 20, “Method of switching the mode.”

* Confirm that history event number [ ] appears on the [Flow Rate/Total Infusion Volume] display.
2. Connect the computer interface connector of the pump and serial port of the external device with a
communication cable.
3. Press and hold the [Purge] switch until the buzzer sounds for confirmation. The pump starts the transmission
of its history data. Confirm that the [Pilot] lamp blinks in green while the data is being transmitted.
4. Confirm that the [Pilot] lamp turns off and the buzzer sounds when the transmission is completed. Disconnect
the communication cable.
5. The initial settings for serial communication are as follows. If the settings are changed, consult our sales
representative in charge:

Baud rate Data length Parity bit Stop bit length

9600 [bps] 8 Even 1

Indicating the time for periodic maintenance

The pump indicates that it is the time for periodic

maintenance after a certain time has elapsed.
[ ] appears on the [Flow Rate/Total Infusion
Volume] display when the self-check is completed.
(Fig. 43)
* Pressing any switch returns the display to the
default mode.

Caution
It is about the time for periodic maintenance.
Maintenance and service are required. Contact
Fig. 43
our sales representative in charge.

25
Other operational procedures
Displaying the total operation time
Total operation time from the pump is put into service and up to the present can be displayed. Contact our sales
representative in charge.

Setting of maximum flow rate

The maximum flow rate can be set in the range of 0.1 - 300.0 (mL/h). Contact our sales representative in charge.
* Purge rate can not be changed.

Changing the syringe brand

Syringes of the following brands are compatible with the pump.

The syringe brand setting in the pump can be changed by shifting the internal switch. Contact our sales
representative in charge. (Fig. 44)

indication Manufacturer or type indication Manufacturer or type indication Manufacturer or type

NIPRO(JAPAN) 10-20-30-50mL
NIPRO(Overseas) 10-20-30-50mL
TERUMO(JAPAN) 10-20-30-50mL
TREUMO(USA) 10-20-30-50mL
JMS(JAPAN) 10-20-30-50mL
Currently not in use.
TOP(JAPAN) 10-20-30-50mL
Currently not in use.
Currently not in use.
HINDUSTAN 20-50mL
ROMSON 20-50mL
ALSHIFA 10-20-50mL
BBRAUN(JAPAN) 10-20-30-50mL
SHERWOOD(JAPAN) 60mL
B-D(JAPAN) 10-20-30-60mL

[Flow Rate/Total
Infusion Volume]
display

Fig. 44

Warning
• If the specifications of the above syringe are changed, the accuracy and alarm functions may not be
guaranteed. Consult our sales representative in charge.
• If the brand of the syringe to be used does not correspond to the syringe setting in the pump, alarm functions
can not be guaranteed as flow rate error exceeding the tolerance may arise.

Setting of serial communication

Settings for serial communication can be adjusted. The following parameters are changeable. Contact our sales
representative in charge.

Baud rate [bps] 4800, 9600, 19200, 38400

Parity bit None, Odd, Even
Stop bit length 1, 2

26
After Operation
Cleaning

If the fluid splashes on the pump during or after operation, wipe the fluid immediately with a cloth. Also,
clean the pump with a wet cloth on a regular basis.

Caution
• Power off and remove the AC power code before cleaning.
• Do not immerse the pump in water.
• Do not sterilize or autoclave the pump.
• Do not use thinner or alcohol for cleaning.

27
How to deal with alarm and trouble
Alarm or trouble occurs, the following things could be suspected as the cause(s). Take corrective actions
according to these instructions. If failure is not corrected, contact your local Nipro dealers.
Key Word Symptom
Power supply AC connect lamp does not
light after connecting AC
power source.
The power is not turned on
with the internal battery.
Internal battery Display does not correspond
to the scale of operation time.
Display “bU_*” appears on the [Flow
Rate / Total Infusion Volume]
display. (“*” is a number.)
“OCC*” appears on the [Flow
Rate / Total Infusion Volume]
display. (“*” is a number.)
“QUA*” appears on the [Flow
Rate / Total Infusion Volume]
display. (“*” is a number.)
“PF5*” appears on the [Flow
Rate / Total Infusion Volume] mode to prefilled syringe.
display. (“*” is a number or -.)
“AdCL” appears on the [Flow
Rate / Total Infusion Volume]
display momentarily, then 4
digit number appears.
“H***” appears on the [Flow
Rate / Total Infusion Volume]
display. (“*” is a number.)
“P” appears on the 3rd digit of The device is in prefilled
integer on the [Flow Rate / syringe mode.
Total Infusion Volume] display.
“PF5*” blinks on the [Flow
Rate / Total Infusion Volume]
display. (“*” is a number or -.)
[Battery] lamps blink.
“E_**” appears on the [Flow
Rate / Total Infusion Volume]
display. (“*” is a number.)
“-OH-” blinks on the [Flow
Rate / Total Infusion Volume]
display.
Indicators and the display
works irregularly.
28
Cause
The AC power inlet does not
connect properly to the AC
power source.
AC power code is snapped.
Otherwise the system is
suspected to be in trouble.
The internal battery runs
short in capacity.
The internal battery has run
out its lifetime.
Otherwise, the system is
suspected to be in trouble.
The internal battery should be
checked periodically.
The device is in alarm volume
switching mode.
The device is in occlusion
detection level switching
mode.
The device is in nearly empty
alarm timing switching mode.
The device is in switching
The device is in date and time Pressing the [Stop] switch puts the
setting mode.
The device is in history mode. Pressing the [Stop] switch puts the
The device is in simple
switching mode to prefilled
syringe.
The pump is operated on
battery.
The system is suspected to
be in trouble
The maintenance date is due.
The system is suspected to
be in trouble
Corrective actions
Check the AC power inlet.
Exchange the AC power code.
Contact your local Nipro dealer.
After connecting to AC power source,
recharge the internal battery for 15 hours
or more. If the power is not turned on
even after such recharging, the internal
fuse of the main unit may be
disconnected. Contact your local Nipro
dealer.
The internal battery must be replaced.
Contact your local Nipro dealer.
By referring the “Periodic Check-Up”
Pressing the [Stop] switch puts the
device back to the normal operation.
Pressing the [Stop] switch puts the
device back to the normal operation.
Pressing the [Stop] switch puts the
device back to the normal operation.
Pressing the [Stop] switch puts the
device back to the normal operation.
device back to the normal operation.
device back to the normal operation.
Please contact our sales
representative.
Please contact our sales
representative.
[Battery] lamps will stay lit when AC
power source is connected.
Ask for repair.
Ask for inspection and maintenance.
Ask for repair.
 How to deal with alarm and trouble
Key Word Symptom Cause Corrective actions
Start Infusion Even when the “Start Button” is Flow rate is specified Confirm the specified flow rate.
pressed, the buzzer sounds, correctly.
and the pump is not start.
“Syringe Load In-completion The syringe brand, which is Confirm the syringe setting. To change
Lamp” illuminates and “Pilot used, may not correspond the setting of syringe brand, contact
Lamp” flashes in red. from the setting. your local Nipro dealer.
Syringe Plunger is not Set the syringe correctly.
properly engaged.
Slider hook is not properly engaged. Set the syringe correctly.
Otherwise, the system is Contact your local Nipro dealer.
suspected to be in trouble.
Flow Rate The pump does not infuse the The infusion line is not Press the “Stop Button” to stop infusion and
solution. released or made the priming. clamp the infusion line. Set the syringe plunger
correctly, make the priming and start infusion.
The accuracy of flow rate is The syringe brand which is Confirm the syringe setting. To change
questionable. used, may not correspond the setting of syringe brand, contact
from the setting. your local Nipro dealer.
Syringe is not properly engaged. Set the syringe properly.
Otherwise the system is in trouble. Contact your local Nipro dealer.
Alarm “Reminder “Reminder Alarm Lamp” “Start Button” is not pressed. Press the “Start Button”
Alarm Lamp” illuminates and “Pilot Lamp”
blinks in red. Buzzer sounds.
Alarm [Syringe [Syringe Load In-completion] The syringe is disengaged Close the infusion line and reload the syringe.
Load In-completion] alarm lamp] lamp turns on and during infusion. Prime the line taking care not to deliver the
the buzzer sounds. The [Pilot] solution to the patient. Switch the flow to the
lamp illuminates in red and patient and open the infusion line. Press the
infusion stops. [Start] switch to commence infusion.
Alarm has recurred and infusion The system is suspected to Ask for repair.
has stopped again after re-start. be in trouble
[Syringe Load In-completion] The brand of the syringe Check the syringe brand setting in the
alarm lamp] lamp has turned loaded does not match the pump and the brand of the syringe
on and the [Pilot] lamp brand of the syringe set in the loaded. If you need to change the
illuminates in red. pump. syringe brand setting in the pump,
contact our sales representative.
The syringe is not held by the Load the syringe correctly.
syringe clamp.
The flange of the syringe plunger Load the syringe correctly.
is not held by the syringe hook.
If none of the above is found, the Ask for repair.
system may be malfunctioning.
Alarm lamps stay lit even after The system is suspected to Ask for repair.
the above remedies are taken. be in trouble
Alarm “Nearly “Nearly Empty Lamp” flashes, The volume of solution in To continue the infusion, replace the
Empty” and the buzzer sounds. syringe runs short. syringe. Buzzer can be silenced by
pressing the “Mute Button.”
The “Nearly Empty Lamp” The syringe has been pushed To continue the infusion, replace the
illuminate and “Pilot Lamp” out. syringe. Buzzer can be silenced by
flash in red, the buzzer sounds, pressing the “Mute Button.”
and the pump is stopped.
After the above action, the The system is in trouble. Contact your local Nipro dealer.
alarm is still running.
Alarm “Occlusion” The “Occlusion Pressure The infusion line is occluded. First, clamp the infusion line. Confirm that the
Alarm Lamp” illuminate and infusion line is not occluded. If any irregularity
“Pilot Lamp” flash in red, the is found, remove the cause of the problem.
buzzer sounds, and the pump After removing the line, make the priming and
is stopped. start the infusion.
When infusion is re-started, The system is suspected to Contact your local Nipro dealer.
the buzzer sounds again, and be in trouble
the pump is stopped.
Occlusion has occurred in the The internal pressure in the Release the internal pressure of the infusion line
infusion line. infusion line higher than the and restart the infusion. If the alarm is still goes
set level. on, set the occlusion pressure level to high.

29
How to deal with alarm and trouble
Error Code list

If [ ]-[ ] appears on the [Flow Rate/Total Infusion Volume] display and the alarm sounds as the
result of self-diagnosis at the time of power-on and or during device operation, the device may be malfunctioning.
Stoptop using the pump immediately and contact our sales representative.

Indication Content of error

Trouble of internal electric circuit

Trouble of internal electric circuit

Trouble of internal electric circuit

Trouble of motor

Trouble of motor

Trouble of drive unit

Trouble of drive unit

Trouble of internal electric circuit

Trouble of internal electric circuit

Trouble of internal electric circuit

*
* [*] appears as a number. [ _ ] appears as blank or space.

30
Maintenance and inspection
Maintenance and inspection are required for safe operation and the longest possible life of the syringe pump.

Cautions for Maintenance and inspection

Warning
Stop using the pump immediately and contact our sales representative in charge if any abnormality is found.

When the pump has been subjected to impact such as by dropping

Warning
If the syringe pump has been subjected to impact such as by dropping, stop using the pump immediately even if it
appears normal externally and no abnormality in operation is found. Contact our sales representative in charge.

Syringes to be used for Maintenance and inspection

Caution
• Use the disposable 10 mL, 20 mL, 30 mL, or 50(60) mL syringes from the specified manufacturers.
• Always use a new syringe for Maintenance and inspection.

Replacement parts
Periodic replacement parts
Periodic replacement parts are the parts that wear and tear over time after the syringe pump has been put into
use and need replacement for keeping their accuracy and function. The parts below may need replacement after
the time shown in the table has elapsed.

Replacement part Time elapsed Reason for replacement

Battery 1.5 ~ 2 years The [Battery Indication] lamp illuminates in red shortly after
the battery has been fully charged.
Upper case Unit (operational 1.5 ~ 2 years Pressing the switch fails or takes time to make the desired input.
panel)
Stepping Motor 2~3 years Abnormality in flow rate is found or noise is heard during infusion.
Main Board (Button Battery) 6~7 years The date and time is not correct.
Clutch Lever 1.5 ~ 2 years Abnormality in flow rate/occlusion detection is found.
Packing for Rod Set 1.5 ~ 2 years Abnormality in slider movement is found.
Rubber Foot 5~6 years The pump rattles or tends to slip when placed on a flat surface.
Slider Rubber 1.5 ~ 2 years The flange of the syringe plunger easily dislocates.
Syringe Clamp O Ring 1.5 ~ 2 years Abnormality in slider clamp movement is found.
Syringe Clamp Set 1.5 ~ 2 years [Syringe Load In-completion] alarm will not turn off, or lights
on frequently.

* The replacement timing for the above parts may differ depending on frequency of the pump use and operating
environment. Consult our sales representative in charge to determine whether a part is necessary to be
replaced or not.
* The useful life of this syringe pump is 5 years. When the pump comes to the end of its useful life, ask for
Maintenance and inspection that may include comprehensive parts replacement.
* The pump should be opened for repair only by our trained service personnel. If the pump is opened for repair by
any person other than our trained service personnel, we will not assume any warranty for the functions.

Replacing the fuse

The fuses are integrated inside the pump. Contact our sales representative in charge.
31
Maintenance and inspection
Periodic check-up points, methods, and cycle

Devices and materials for check-up

Locate the following devices and materials before check-up (excluding the check-up before each use).
1. 50 mL syringe filled with water
(The air in the syringe should be removed)
* Use a syringe from the specified manufacturers
2. Stopwatch
3. Water
4. Measuring cylinder (50 mL) with the graduations of 1.0 mL or smaller
5. Forceps (Kocher clamp)
6. Tube

Check-up before each use

Check the followings prior to each use.

[Check-up method]
1. There is no visible damage to the pump and pole clamp.
2. Pump can be operated on internal battery.
3. [AC Connect] lamp illuminates when the AC power cord is connected to the pump without turning on the
[Power] switch.
4. The pump performs self-check as the following when the [Power] switch is pressed to turn on the pump.
(1) All the lamps blink.
(2) The syringe brand is displayed.

indication Manufacturer or type indication Manufacturer or type indication Manufacturer or type

NIPRO(JAPAN) 10-20-30-50mL
NIPRO(Overseas) 10-20-30-50mL
TERUMO(JAPAN) 10-20-30-50mL
TREUMO(USA) 10-20-30-50mL
JMS(JAPAN) 10-20-30-50mL
Currently not in use.
TOP(JAPAN) 10-20-30-50mL
Currently not in use.
Currently not in use.
HINDUSTAN 20-50mL
ROMSON 20-50mL
ALSHIFA 10-20-50mL
BBRAUN(JAPAN) 10-20-30-50mL
SHERWOOD(JAPAN) 60mL
B-D(JAPAN) 10-20-30-60mL

(3) Occlusion detection level is displayed.

Indication Occlusion Pressure Detection Level

L : 40 ± 20 kPa

M : 70 ± 25 kPa

H : 100 ± 30 kPa

5. Occlusion should be detected when 10 mL, 20 mL, 30 mL, and 50 mL syringes from the specified
manufacturers are loaded.
6. The [Syringe Load In-completion] alarm lamp should illuminate and the [Pilot] lamp should be lit in red when a
syringe is not loaded. The lamps should go off when a syringe is loaded.
7. The infusion should be stopped when the [Stop] switch is pressed during infusion.

32
 Maintenance and inspection
Check-up method for occlusion detection function (once in a month)

Please check the occlusion detection at least once in

a month using the following procedures. Forceps (Kocher clamp)

[Check-up method] Tube

1. Turn on the power.
2. Set the occlusion detection pressure to
M (OCC2).
3. Connect a tube securely to a syringe filled with
water and load the syringe onto the pump. Pump

(Fig. 45)
4. Keep holding down the [Purge] switch until the Fig. 45
water drips from the tube tip.
5. Pinch the midstream of the tube with a forceps Flow rate setting 50 mL/h

Settings
(Kocher clamp) and set the flow rate to 50 mL/h.
Occlusion detection
(Fig. 45) pressure setting M (OCC2)
6. Press the [Start] switch and start a stopwatch at Distance from the syringe
the same time. Take the time till occlusion to the forceps Within 5 mm
alarm.
ment taken
Measure-

Time to [Occlusion] alarm Approx. 120 -

240 seconds

Check-up method for flow rate accuracy (once in two months)

Please check the flow rate accuracy at least once in

two months using the following procedures.

Measuring Tube
[Check-up method] cylinder
1. Turn on the power.
2. Connect a tube securely to a syringe filled with
water and load the syringe onto the pump.
(Fig. 46)
3. Keep holding down the [Purge] switch until the Pump

water drips from the tube tip.

4. Press the [Clear] switch to clear the total infusion Fig. 46
volume.
Settings

5. Put the tube tip into the measuring cylinder and Flow rate setting 70 mL/h
set the flow rate to 70 mL/h.
6. Press the [Start] switch and start a stopwatch at Operation time 30 minutes
the same time. Press the [Stop] switch to stop
Check

the pump after 30 minutes. Total infusion volume 35 mL

7. Check that the total infusion volume displayed
ment taken

and the amount of water in the measuring

Measure-

cylinder corresponds. (Fig. 46) Amount in the measuring

34 - 36 mL
cylinder

33
Maintenance and inspection
Check-up method for the internal battery (once in a month)

This pump has a internal battery as the auxiliary power source.

The internal battery deteriorates over time regardless of its use and needs periodic replacement. The
replacement timing may vary depending on the frequency of use and the operational environment of the pump.
Battery check-up procedure
Test condition/
Item
Criteria for normality
Charge at least 15 hours with the
AC mains connected.
<Normal> 3 lamps illuminate
Charge
Operate the pump on battery at the
flow rate of 5.0 mL/h with a 50 mL
syringe loaded and wait until the
power shuts down.
Discharge <Normal> The pump operates on
battery for approx. 2 hours.
Abnormal state
Only 2 green lamps
illuminate.
Only 1 green lamp
illuminates.
One red lamp illuminates.
The pump operates on
battery for less than 1 hour.
Although 2 or 3 [Battery
Indication] lamps illuminate
when the power turned on the
battery, only 1 lamp stays lit
after a short while.
Remedy
Battery is deteriorating.
Please keep in mind that the battery
needs replacement.
Battery has deteriorated. Battery
replacement is required. Contact our
sales representative in charge.
Battery has deteriorated. Battery
replacement is required. Contact our
sales representative in charge.
Battery is deteriorating.
Please keep in mind that the battery
needs replacement.
Battery has deteriorated. Battery
replacement is required. Contact our
sales representative in charge.

Caution
• Perform the check-up with the ambient temperature of 25°C.
• After replacing the internal battery with a new one, always check the internal battery function according to the
internal battery check-up procedure above.
Remaining internal battery amount can not be displayed correctly without performing this procedure.
• Perform the internal battery check-up procedure when putting the pump into use at the first time after
purchase or after it has not been used for a long time.
• If any abnormality is found during the internal battery check-up procedure, contact our sales representative in

Periodic maintenance

Maintenance and inspection are required at least once a year for safe operation and the longest possible life of
the syringe pump. Contact our sales representative in charge for the periodic inspection.

Warning
If any abnormality is found, stop using the pump immediately. Contact our sales representative in charge.

Caution
• Use only the specified replacement parts.
• Do not disassemble or try to repair the pump as this may worsen the malfunction. We will not assume any
warranty for the pump disassembled or modified by the user or a third party without prior approval from us, or
used for the purposes other than intended.
• The pump needs service even if it appears normal externally and no abnormal operations are observed after
it has been subjected to impact such as dropping as the inside may be damaged. Contact our sales
representative in charge.

34
 Maintenance and inspection
Periodic inspection check-list

Serial number: Date: / / Checked by:

Check-up before each use

1 Is there any abnormality such as visible damage to the pump or the pole clamp? OK NG
2 Does the pump operate on internal battery? OK NG
Does the [AC Connect] lamp illuminate when the AC power cord is connected without the
3 OK NG
power turned on?
Does the pump perform self-check when the [Power] switch is turned on?
4 (The buzzer sounds and all the lamps blink.) OK NG

5 Does the pump recognize 10, 20, 30, and 50 mL syringes? OK NG

Do the [Syringe Load In-completion] alarm lamp illuminate and the [Pilot] lamp turn on
6 in red when a syringe is not loaded? Do these lamps go off when a syringe is loaded? OK NG

7 Does the pump stop when the [Stop] switch is pressed during infusion? OK NG

Occlusion detection function check-up (once in a month)

Does the [Occlusion] alarm sounds within the specified time range?
8 (About 120-240 seconds: 50 mL syringe, flow rate of 50 mL/h, and occlusion detection OK NG
pressure set to M)

Flow rate accuracy check-up (once in two months)

Is the flow rate accuracy within the specified range?
9 (34-36 mL: 50 mL syringe, flow rate of 70 mL/h, and operation time of 30 minutes) OK NG

Internal battery check-up (once in a month)

10 Does the pump operate on battery at least 1 hour? (5 mL syringe, flow rate of 5 mL/h) OK NG

Final Judgment (If there is at least 1 NG in the above check-up list, the pump needs service.) OK NG
Remarks:

Warning
If any abnormality is found, stop using the pump immediately. Contact our sales representative in charge.

35
SPECIFICATIONS
Brand name......................Nipro Smartfusion
Code number ...................CSP-100NE/CSP-100NS
Syringe to be used ...........10, 20, 30, 50 mL of specified brands
Flow rate setting range.....0.1 - 300.0 mL/h (Max flow rate can be set in the range of 0.1-300.0 mL/h
using the max flow rate setting function.)
Total infusion volume
display range ....................0.1 - 999.9 mL
Purge rate setting .............NIPRO, TERUMO, JMS, TOP, HINDUSTAN, ROMSON, ALSHIFA, BBRAUN,
SHERWOOD, B-D
10 mL syringe : 300 mL/h
20 mL syringe : 500 mL/h
30 mL syringe : 700 mL/h
50(60) mL syringe: 1200 mL/h
Flow rate accuracy ...........Mechanical accuracy: within ±1%
Accuracy including the syringe: within ±3%
(Accuracy of every 1 hour after 1 hour has elapsed since the start of infusion
with a new syringe and at a flow rate of 1.0 mL/h or over)
Occlusion detection
accuracy ...........................Selectable from three levels
[H]: 100±30 kPa (750.1±225.0 mmHg) (1.02±0.31 kgf/cm2)
[M]: 70±25 kPa (525.0±187.5 mmHg) (0.71±0.26 kgf/cm2)
[L]: 40±20 kPa (300.0±150.0 mmHg) (0.41±0.20 kgf/cm2)
Alarm system ...................Nearly empty, Occlusion, Start Reminder, Syringe Load In-complete, and
Internal battery
Special functions ..............1. Alarm volume switching: selectable from 3 levels
2. Occlusion detection pressure switching: selectable from 3 levels
3. Nearly empty alarm timing switching: selectable from 3 levels
4. Repeat alarm: Alarm repeats if the alarm state has not remedied for more
than 2 minutes after the alarm sound cancellation.
5. Shutdown: Power automatically shuts off if the voltage falls below a
certain level when the pump is operated on the internal battery.
6. Power cord disconnection: Alarm sounds when the power cord is
disconnected while the pump is turned on.
7. Simple switching method to PFS: simple method to switching the syringe
setting to PFS
8. Clearing the total infusion volume: Keep pressing the [Clear] switch clears
the total infusion volume.
9. Syringe size recognition: Displays the syringe size loaded.
10. Internal battery remaining amount: Indicates in 4 levels
11. Key lock: Negates the input from the switches.
12. History: Displays the operation history (stores maximum 200 events)
13. Maximum flow rate setting: Maximum flow rate can be set in the range of
0.1-300.0 mL/h.
14. Syringe brand switching: Usable syringe brand setting in the pump can
be changed.
15. Maintenance time indication: Indicates when it is about the time for
maintenance.
16. Displaying the total operation time: Displays the total operation time
Operational conditions ....Ambient temperature: 5 - 40°C Relative humidity: 20 - 90% (without
condensation)
Storage conditions..........Ambient temperature: -20 - 45°C Relative humidity: 10 - 95% (without

36
 SPECIFICATIONS
condensation)
Power source....................AC100V - 240V 50/60Hz
Operable time on internal battery: approx. 2 hours
(In case of a new internal battery, ambient temperature of 25°C, after charge
of at least 15 hours with the power-off, and flow rate of 5 mL/h)
Power consumption ..........20VA at. AC240V
12VA at. AC100V
Classification ....................Class I and internally powered equipment, Type CF applied part, IPX1 (Drip
proof)
EMC standard ..................In compliance with JIS T 0601-1-2:2002
External dimensions.........223 (width) x 95 (height) x 108 (depth) mm (excluding protrusions)
Weight ..............................Approx. 1.5 Kg

37
MEMO
MEMO
NIPRO CORPORATION
3-9-3 Honjo-nishi, Kita-ku, Osaka 531-8510, Japan
Phone : +81-6-6372-2331
Fax : +81-6-6371-7422
http : //www.nipro.co.jp/english/