WHAT IS IMMUNOLOGY?

Immunology is the study of the body’s

mechanisms that
(1) discriminate between self and non-self,
and
THE IMMUNE SYSTEM (2) eliminate non-self components such as
Carlo Chris S. Apurillo
College of Medical Technology
RTR Medical Foundation
infectious agents.
(Stanley, 2002)

SIGNIFICANT MILESTONES IN IMMUNOLOGY

WHAT IS SEROLOGY? ➤

➤
1798
Edward Jenner
➤ smallpox vaccination
Serology is the scientific study of serum and
other body fluids.
SIGNIFICANT MILESTONES IN IMMUNOLOGY SIGNIFICANT MILESTONES IN IMMUNOLOGY
➤ 1862 ➤ 1880-1881
➤ Ernst Haeckel ➤ Pasteur
➤ phagocytosis ➤ Live, attenuated chicken
cholera and anthrax vaccines
➤ 1885
➤ Therapeutic vaccination; first
report of live “attenuated”
vaccine for rabies

SIGNIFICANT MILESTONES IN IMMUNOLOGY SIGNIFICANT MILESTONES IN IMMUNOLOGY

➤ 1883-1905 ➤ 1890
➤ Elie Metchnikoff ➤ Emil Adolf von Behring
➤ Cellular theory of immunity ➤ Shibasaburo Kitasato
through phagocytosis ➤ Humoral theory of immunity
proposed
SIGNIFICANT MILESTONES IN IMMUNOLOGY SIGNIFICANT MILESTONES IN IMMUNOLOGY
➤ 1900 ➤ 1949
➤ Paul Ehrlich ➤ Jonas Salk
➤ Antibody formation theory ➤ Albert Sabin
➤ Development of polio vaccine

SIGNIFICANT MILESTONES IN IMMUNOLOGY

➤ 2005
➤ Ian Frazer
➤ Development of human
papilloma virus vaccine

THE IMMUNE
SYSTEM
functions?
INNATE VS. ADAPTIVE IMMUNITY INNATE VS. ADAPTIVE IMMUNITY

Source: http://nfs.unipv.it/nfs/minf/dispense/immunology/lectures/files/evolution_immunity.html

Source: http://freaksnotgeeks.blogspot.com/2008/11/overview-of-adaptive-immunity-antigens.html

BODY DEFENSES: FIRST LINE OF DEFENSE BODY DEFENSES: SECOND LINE OF DEFENSE
➤ skin
➤ mucous membranes
➤ cilia
➤ normal flora
➤ acidity of the vagina
➤ secretions
➤ mucus
➤ sebum
➤ cerumen
➤ gastric juice
➤ tears
➤ sweat
BODY DEFENSES: SECOND LINE OF DEFENSE BODY DEFENSES: THIRD LINE OF DEFENSE

inflammation
phagocytosis

INNATE VS. ADAPTIVE IMMUNITY

Source: http://freaksnotgeeks.blogspot.com/2008/11/overview-of-adaptive-immunity-antigens.html