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Which of the following is the most likely explanation for multiple drug resistance to
antibiotics that has increased from one type of bacteria to other type of bacteria?
a) Adaptation
b) Decreased bioavailability
c) Gene transfer
d) Mutation
e) Pharmacogenetic
ANSWER: C
B C
Increase in cardiac force
3. Which of the following provides information about the largest response a drug can
produce regardless of dose?
a. Drug potency
b. Maximal efficacy
c. Mechanisms of receptor action
d. Therapeutic index
e. Therapeutic window
4. Which of the following drugs has no antibacterial effect but use in combination with beta-
lactam antibiotics due to its penicillinase inhibitory effect
a. sulbactam
b. vankomycin
c. aztreonam
d. chloramphenicol
e. nafcillin
5. 1. Which of the following drugs is bactericidal?
6. a) Macrolides
7. b) Chloramphenicol
8. c) Sulphonamides
9. d) Ampicillin
10. e) Etambutol
11. 2. Please indicate the selective antimicrobial drug.
12. a) Inhibitors of protein synthesis
13. b) Antimicrobials that bind to 30s subunit
14. c) Folate synthesis inhibiting sulfonamides
15. d) Antimicrobials that bind to 50s subunit
16. e) Inhibitors of nucleic acid synthesis
6. Indicate the drug that acts via H2 histamine receptors when used in the
treatment of gastroduedonal ulcers.
a) Omeprazole
b) Famotidine
c) Aluminum hydroxide
d) Sodium bicarbonate
e)Lansoprazole
15. The phenomenon that you observed when you administer a combination of
morphine and petidine to rats on analgesic threshold is called................
a) Addition b) Subtraction
c) Synergism d) Antagonism
e)Agonisnm
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18. Which of the following is a general (nonspecific) CNS depressant?
a) Morphine
b) Naloxone
c) Anesthetic gases and vapors
d) Meperidine
e) Codeine
a) Methadone
b) Codeine
c) Tebaine
d) Naloxone
e) Papaverine
? 21. Morphine interacts with which of the following subtype of opioid receptors?
a) κ
b) δ
c) μ
d) Є
e) All
22. Indicate the one that is not among clinical uses of H2 receptor antagonists.
a) Peptic duodenal ulcer
b) Erosive Esophagitis (GERD)
c) Allergic reactions
d) Gastric ulcer
e) Hypersecretory conditions
23. Which of the following receptors of Histamine is responsible for gastric acid
secretion?
a) H1 b) H2
c) H3 d) H4
e) H5
24. Which of the following is not among uses of the H2 Histamine antagonists?
a) Gastroesophageal reflux disease b) Heartburn
c) Dispepsia d) Peptic ulcer caused by H pylori
e) Nonulcerdispepsia
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25. Which of the following is not derived from opium poppy, papaver
somniferum?
a) Morphine
b) Codeine
c) Tebaine
d) Papaverine
e) Enkephalin
39. Which of the following is not observed in an individual during the abstinence
syndrome of morphine dependence?
a) Ptosis b) Diarrhea
c) Sedation d) Sweating
e) Tremors
1. Choose the correct one for the mechanism of action for Amphotericin B.
a) Has greater affinity for mammalian plasma membrane cholesterol than
for fungal plasma membrane ergosterol
b) Has greater affinity for fungal plasma membrane ergosterol than for
mammalian cholesterol
c) Has equal affinity for fungal plasma membrane ergosterol as for
mammalian cholesterol
d) Inhibits protein synthesis in the 30s subunit of the ribosomes
e) Inhibits protein synthesis in the 50s subunit of the ribosomes
A) Propranolol – Salbutamol
B) Tetracyclin – Calcium
C) Phenytoin – theophylline
D) Antacid – iron
E) Itraconazole – Verapamil