Professional Documents
Culture Documents
DAFTAR PUSTAKA
12. Global Burden of Viral Hepatitis [database on the internet]. WHO Geneva.
2010 [cited 12 Desember 2013]. Available from: http://
www.who.int/evidence/bod.
13. Hepatitis B and HIV Coinfecton Clinical Protocol [database on the internet].
WHO European Region. 2010 [cited 16 Desember 2013].
14. Laporan Hasil Riset Kesehatan Dasar RISKESDAS Indonesia [database on
the internet]. Departemen Kesehatan. 2007 [ cited 2 Januari 2014].
15. Profil Kesehatan 2008 [database on the internet]. Departemen Kesehatan.
2009 [cited 2 Januari 2014]. Available from: http//www.depkes.go.id .
16. Setiawati, M. Perbandingan Validitas Maddrey’s Discriminant Function dan
Skor Child-Pugh dalam Memprediksi Ketahanan Hidup 12 Minggu pada
Pasien Sirosis Hepatis. Semarang: Fakultas Kedokteran Universitas
Diponegoro; 2009.
17. Deep vein thrombosis in patient with cirrhosis [database on the internet].
Lesmana, dkk. 2009 [cited 16 Januari 2014]. Available from:
http://www.who.int/research/en.
18. Simamora, C. T. Hubungan Komplikasi, Skor Child-Turcotte dan Usia Lanjut
Sebagai Faktor Resiko Kematian Pada Pasien Sirosis Hati di RSUD Dr.
Soedarso Pontianak. Pontianak; 2013.
19. Malau, A. S. Karakteristik Penderita Sirosis Hati Yang Dirawat Inap Di
Rumah Sakit Martha Friska Medan Tahun 2006-2010. Medan; 2011.
20. Report of The Regional Committee for the Eastern Mediterranean Fifty-sixth
Session Fez, Morocco 5–8 October 2009 [database on the internet]. Mohsni.
2009 [cited 6 Pebruari 2014]. Available from: http://search.who.int/.
21. Statistics by Country for Cirrhosis of the liver [database on the internet]. US
Census Bureau, International Data Base. 2005 [cited 11 Januari 2014].
Available from: http://www.cureresearch.com/c/cirrhosis_of_the_liver/stats-
country_ printer.htm.
22. Ndraha. The Indonesian Journal of Gastroenterology, Hepatology, and
Digestive Endoscopy. Volume 10, Number 3; 2009.
23. Hadi, S. Gastroenterologi. Bandung: Penerbit Alumni Bandung; 2002.
51
34. Arguedes MR, Fallon MB. Cirrhosis of the liver and its complications. In:
Carpenter CCJ, Griggs RC, Loscalzo J, editors. Cecil essentials of medicine.
Edisi XI. Pennsylvania: Saunders, 2004: 411-7.
35. Price S.A. Patofisiologi konsep Klinis Proses-proses Penyakit, Edisi VI.
Jakarta: EGC; 2006.
36. Kayacetin E, Efe D, Dogan C. Portal and splenic hemodynamics in cirrhotic
patients: relationship between esophageal variceal bleeding and the severity
of hepatic failure. Journal of Gastroenterology, 2004; 39: 661-7.
37. Friedman SL, McQuaid KR, Grendell JH. Current diagnosis and treatment in
gastroenterology. 2nd ed. New York: Mc Graw Hill, 2003: 644-62.
38. Porth CM. Pathophysiology: concepts of altered health states. 5th ed.
Philadelphia, 1998: 761-6.
39. Weiss GR. Clinical oncology. Connecticut: Appleton & Lange; 1993.
40. Cardenas A, Arroyo V. Mechanism of water and sodium retension in
cirrhosis and the phatogenesis of ascites. Best Pract Res Clin Endokrinol
Metab 2003; 17: 607-22.
41. Cheney CP, Goldberg EM, Chopra S. Cirrhosis and portal hypertension: an
overview. In: Friedman LS, Keeffe EB, editors. Handbook of liver disease.
2nd ed. China: Churchill Livingstone, 2004: 125-37.
42. Gilroy J. Basic neurology. 3rd ed. New York: Mc Graw Hill, 2000: 517-8.
43. Hassan HA. Spontaneous Bacterial Peritonitis. Dalam: Adi S, editor. Naskah
lengkap pendidikan kedokteran berkelanjutan XVI. Surabaya: Laboratorium
SMF Penyakit Dalam FK Unair RSUD Dr. Sutomo, 2001: 41-59.
44. Hirlan. Nutrisi enteral dan parenteral pada penderita penyakit hati kronik.
Dalam: Soeroso S, Haryoko W, Setiati TE, Kosim HMS, Triwara B, editor.
Gizi klinik: Nutrisi enteral dan parenteral. Badan Penerbit Universitas
Diponegoro; 1994.
45. Doubatty, AC. 2009. Perbandingan validitas skor mayo end stage liver
disease dan skor child-pugh dalam memprediksi ketahanan hidup 12 minggu
pada pasien sirosis hepatis. Semarang: Universitas Diponegoro.
53
Statistics
Albumin Lama
Usia Bilirubin Total serum PPT perawatan
N Valid 303 245 259 226 303
Missing 2 60 46 79 2
Mean 54.17 4.4606 2.3448 8.1827 10.46
Median 54.00 1.9800 2.3000 5.3000 9.00
St d. Dev iation 11.755 5.92105 .60094 12.46432 7.626
Minimum 16 .11 .90 -.90 0
Maximum 81 36.31 4.66 106.30 48
NPar Tests
Albumin Lama
Usia Bilirubin Total serum PPT perawatan
N 303 245 259 226 303
Normal Parameters a,b Mean 54.17 4.4606 2.3448 8.1827 10.46
St d. Dev iation 11.755 5.92105 .60094 12.46432 7.626
Most Extreme Absolute .062 .231 .064 .239 .145
Dif f erences Positiv e .062 .221 .064 .232 .145
Negativ e -.055 -.231 -.040 -.239 -.101
Kolmogorov -Smirnov Z 1.080 3.620 1.023 3.589 2.522
Asy mp. Sig. (2-tailed) .193 .000 .246 .000 .000
a. Test distribution is Normal.
b. Calculated f rom data.
55
Frequency Table
Cumulat iv e
Frequency Percent Valid Percent Percent
Valid Laki-laki 205 67,7 67,7 67,7
Perempuan 98 32,3 32,3 100,0
Total 303 100,0 100,0
Usia
Cumulat iv e
Frequency Percent Valid Percent Percent
Valid < 31 10 3.3 3.3 3.3
31 - 40 21 6.9 6.9 10.2
41 - 50 79 26.1 26.1 36.3
51 - 60 104 34.3 34.3 70.6
61 - 70 59 19.5 19.5 90.1
> 70 30 9.9 9.9 100.0
Total 303 100.0 100.0
HBV
Cumulativ e
Frequency Percent Valid Percent Percent
Valid Ya 184 60.7 60.7 60.7
Tidak 119 39.3 39.3 100.0
Total 303 100.0 100.0
HCV
Cumulativ e
Frequency Percent Valid Percent Percent
Valid Ya 55 18.2 18.2 18.2
Tidak 248 81.8 81.8 100.0
Total 303 100.0 100.0
56
NAFL
Cumulativ e
Frequency Percent Valid Percent Percent
Valid Ya 21 6.9 6.9 6.9
Tidak 282 93.1 93.1 100.0
Total 303 100.0 100.0
Alkohol
Cumulativ e
Frequency Percent Valid Percent Percent
Valid Tidak 303 100.0 100.0 100.0
Lain-lain
Cumulativ e
Frequency Percent Valid Percent Percent
Valid Ya 59 19.5 19.5 19.5
Tidak 244 80.5 80.5 100.0
Total 303 100.0 100.0
Klasifikasi CHILD-PUGH
Cumulat iv e
Frequency Percent Valid Percent Percent
Valid A 15 5,0 6,4 6,4
B 75 24,8 32,1 38,5
C 144 47,5 61,5 100,0
Total 234 77,2 100,0
Missing Sy stem 69 22,8
Total 303 100,0
57
Cumulativ e
Frequency Percent Valid Percent Percent
Valid Ya 59 19,5 19,5 19,5
Tidak 244 80,5 80,5 100,0
Total 303 100,0 100,0
Ensefalopati Hepatikum
Cumulativ e
Frequency Percent Valid Percent Percent
Valid Ya 66 21,8 21,8 21,8
Tidak 237 78,2 78,2 100,0
Total 303 100,0 100,0
Karsinoma Hepatoseluler
Cumulativ e
Frequency Percent Valid Percent Percent
Valid Ya 34 11,2 11,2 11,2
Tidak 269 88,8 88,8 100,0
Total 303 100,0 100,0
Sindr. Hepatorenal
Cumulativ e
Frequency Percent Valid Percent Percent
Valid Ya 5 1,7 1,7 1,7
Tidak 298 98,3 98,3 100,0
Total 303 100,0 100,0
58
Hematemesis
Cumulativ e
Frequency Percent Valid Percent Percent
Valid Ya 79 26,1 26,1 26,1
Tidak 224 73,9 73,9 100,0
Total 303 100,0 100,0
Melena
Cumulativ e
Frequency Percent Valid Percent Percent
Valid Ya 85 28,1 28,1 28,1
Tidak 218 71,9 71,9 100,0
Total 303 100,0 100,0
Ascites
Cumulativ e
Frequency Percent Valid Percent Percent
Valid Ya 224 73,9 73,9 73,9
Tidak 79 26,1 26,1 100,0
Total 303 100,0 100,0
Cumulativ e
Frequency Percent Valid Percent Percent
Valid Ya 1 ,3 ,3 ,3
Tidak 302 99,7 99,7 100,0
Total 303 100,0 100,0
Gastropati HT Porta
Cumulativ e
Frequency Percent Valid Percent Percent
Valid Ya 39 12,9 12,9 12,9
Tidak 264 87,1 87,1 100,0
Total 303 100,0 100,0
59
Efusi pleura
Cumulativ e
Frequency Percent Valid Percent Percent
Valid Ya 38 12,5 12,5 12,5
Tidak 265 87,5 87,5 100,0
Total 303 100,0 100,0
Pneumonia
Cumulativ e
Frequency Percent Valid Percent Percent
Valid Ya 37 12,2 12,2 12,2
Tidak 266 87,8 87,8 100,0
Total 303 100,0 100,0
TB paru
Cumulativ e
Frequency Percent Valid Percent Percent
Valid Ya 5 1,7 1,7 1,7
Tidak 298 98,3 98,3 100,0
Total 303 100,0 100,0
Syok
Cumulativ e
Frequency Percent Valid Percent Percent
Valid Ya 7 2,3 2,3 2,3
Tidak 296 97,7 97,7 100,0
Total 303 100,0 100,0
60
Sepsi s
Cumulativ e
Frequency Percent Valid Percent Percent
Valid Ya 19 6,3 6,3 6,3
Tidak 284 93,7 93,7 100,0
Total 303 100,0 100,0
Penyakit ginjal
Cumulativ e
Frequency Percent Valid Percent Percent
Valid Ya 10 3,3 3,3 3,3
Tidak 293 96,7 96,7 100,0
Total 303 100,0 100,0
Penyakit jantung
Cumulativ e
Frequency Percent Valid Percent Percent
Valid Ya 3 1,0 1,0 1,0
Tidak 300 99,0 99,0 100,0
Total 303 100,0 100,0
Survival rate
Cumulat iv e
Frequency Percent Valid Percent Percent
Valid Meninggal 60 19,8 19,8 19,8
Hidup 243 80,2 80,2 100,0
Total 303 100,0 100,0
Perut membesar
Cumulativ e
Frequency Percent Valid Percent Percent
Valid Ya 111 36.4 36.4 36.4
Tidak 194 63.6 63.6 100.0
Total 305 100.0 100.0
61
Nyeri perut
Cumulativ e
Frequency Percent Valid Percent Percent
Valid Ya 17 5.6 5.6 5.6
Tidak 288 94.4 94.4 100.0
Total 305 100.0 100.0
Berak darah
Cumulativ e
Frequency Percent Valid Percent Percent
Valid Ya 32 10.5 10.5 10.5
Tidak 273 89.5 89.5 100.0
Total 305 100.0 100.0
Muntah darah
Cumulativ e
Frequency Percent Valid Percent Percent
Valid Ya 63 20.7 20.7 20.7
Tidak 242 79.3 79.3 100.0
Total 305 100.0 100.0
Badan lemas
Cumulativ e
Frequency Percent Valid Percent Percent
Valid Ya 15 4.9 4.9 4.9
Tidak 290 95.1 95.1 100.0
Total 305 100.0 100.0
Penurunan kesadaran
Cumulativ e
Frequency Percent Valid Percent Percent
Valid Ya 18 5.9 5.9 5.9
Tidak 287 94.1 94.1 100.0
Total 305 100.0 100.0
62
Mata kuni ng
Cumulativ e
Frequency Percent Valid Percent Percent
Valid Ya 13 4.3 4.3 4.3
Tidak 292 95.7 95.7 100.0
Total 305 100.0 100.0
Lain2
Cumulativ e
Frequency Percent Valid Percent Percent
Valid Ya 48 15.7 15.7 15.7
Tidak 257 84.3 84.3 100.0
Total 305 100.0 100.0
Ensefalopati
Cumulat iv e
Frequency Percent Valid Percent Percent
Valid grade I-I I 32 10.5 44.4 44.4
grade III -IV 40 13.1 55.6 100.0
Total 72 23.6 100.0
Missing Sy stem 233 76.4
Total 305 100.0
Ascites
Cumulat iv e
Frequency Percent Valid Percent Percent
Valid ringan-sedang 180 59.0 80.4 80.4
berat 44 14.4 19.6 100.0
Total 224 73.4 100.0
Missing Sy stem 81 26.6
Total 305 100.0
63
Surv iv al rate
Meninggal Hidup Total
Jenis kelamin Laki-laki Count 39 166 205
% wit hin Surv iv al rate 65,0% 68,3% 67,7%
% of Total 12,9% 54,8% 67,7%
Perempuan Count 21 77 98
% wit hin Surv iv al rate 35,0% 31,7% 32,3%
% of Total 6,9% 25,4% 32,3%
Total Count 60 243 303
% wit hin Surv iv al rate 100,0% 100,0% 100,0%
% of Total 19,8% 80,2% 100,0%
64
Surv iv al rate
Meninggal Hidup Total
HBV Ya Count 35 149 184
% wit hin Surv iv al rat e 58.3% 61.3% 60.7%
% of Total 11.6% 49.2% 60.7%
Tidak Count 25 94 119
% wit hin Surv iv al rat e 41.7% 38.7% 39.3%
% of Total 8.3% 31.0% 39.3%
Total Count 60 243 303
% wit hin Surv iv al rat e 100.0% 100.0% 100.0%
% of Total 19.8% 80.2% 100.0%
Surv iv al rate
Meninggal Hidup Total
HCV Ya Count 8 47 55
% wit hin Surv iv al rat e 13.3% 19.3% 18.2%
% of Total 2.6% 15.5% 18.2%
Tidak Count 52 196 248
% wit hin Surv iv al rat e 86.7% 80.7% 81.8%
% of Total 17.2% 64.7% 81.8%
Total Count 60 243 303
% wit hin Surv iv al rat e 100.0% 100.0% 100.0%
% of Total 19.8% 80.2% 100.0%
Surv iv al rate
Meninggal Hidup Total
NAFL Ya Count 3 18 21
% wit hin Surv iv al rat e 5.0% 7.4% 6.9%
% of Total 1.0% 5.9% 6.9%
Tidak Count 57 225 282
% wit hin Surv iv al rat e 95.0% 92.6% 93.1%
% of Total 18.8% 74.3% 93.1%
Total Count 60 243 303
% wit hin Surv iv al rat e 100.0% 100.0% 100.0%
% of Total 19.8% 80.2% 100.0%
65
Surv iv al rate
Meninggal Hidup Total
Alkohol Tidak Count 60 243 303
% wit hin Surv iv al rate 100.0% 100.0% 100.0%
% of Total 19.8% 80.2% 100.0%
Total Count 60 243 303
% wit hin Surv iv al rate 100.0% 100.0% 100.0%
% of Total 19.8% 80.2% 100.0%
Surv iv al rate
Meninggal Hidup Total
Lain-lain Ya Count 18 41 59
% within Surv iv al rate 30.0% 16.9% 19.5%
% of Total 5.9% 13.5% 19.5%
Tidak Count 42 202 244
% within Surv iv al rate 70.0% 83.1% 80.5%
% of Total 13.9% 66.7% 80.5%
Total Count 60 243 303
% within Surv iv al rate 100.0% 100.0% 100.0%
% of Total 19.8% 80.2% 100.0%
66
Surv iv al rate
Meninggal Hidup Total
Klasif ikasi A Count 0 15 15
CHI LD-PUGH % within Surv iv al rate ,0% 8,2% 6,4%
% of Total ,0% 6,4% 6,4%
B Count 4 71 75
% within Surv iv al rate 7,7% 39,0% 32,1%
% of Total 1,7% 30,3% 32,1%
C Count 48 96 144
% within Surv iv al rate 92,3% 52,7% 61,5%
% of Total 20,5% 41,0% 61,5%
Total Count 52 182 234
% within Surv iv al rate 100,0% 100,0% 100,0%
% of Total 22,2% 77,8% 100,0%
67
Crosstab
Surv iv al rate
Meninggal Hidup Total
Usia < 31 Count 1 9 10
Expected Count 2.0 8.0 10.0
% wit hin Surv iv al rate 1.7% 3.7% 3.3%
% of Total .3% 3.0% 3.3%
31 - 40 Count 3 18 21
Expected Count 4.2 16.8 21.0
% wit hin Surv iv al rate 5.0% 7.4% 6.9%
% of Total 1.0% 5.9% 6.9%
41 - 50 Count 15 64 79
Expected Count 15.6 63.4 79.0
% wit hin Surv iv al rate 25.0% 26.3% 26.1%
% of Total 5.0% 21.1% 26.1%
51 - 60 Count 19 85 104
Expected Count 20.6 83.4 104.0
% wit hin Surv iv al rate 31.7% 35.0% 34.3%
% of Total 6.3% 28.1% 34.3%
61 - 70 Count 15 44 59
Expected Count 11.7 47.3 59.0
% wit hin Surv iv al rate 25.0% 18.1% 19.5%
% of Total 5.0% 14.5% 19.5%
> 70 Count 7 23 30
Expected Count 5.9 24.1 30.0
% wit hin Surv iv al rate 11.7% 9.5% 9.9%
% of Total 2.3% 7.6% 9.9%
Total Count 60 243 303
Expected Count 60.0 243.0 303.0
% wit hin Surv iv al rate 100.0% 100.0% 100.0%
% of Total 19.8% 80.2% 100.0%
Chi-Square Tests
Crosstab
Surv iv al rate
Meninggal Hidup Total
Ef usi pleura Ya Count 3 35 38
Expected Count 7.5 30.5 38.0
% wit hin Surv iv al rate 5.0% 14.4% 12.5%
% of Total 1.0% 11.6% 12.5%
Tidak Count 57 208 265
Expected Count 52.5 212.5 265.0
% wit hin Surv iv al rate 95.0% 85.6% 87.5%
% of Total 18.8% 68.6% 87.5%
Total Count 60 243 303
Expected Count 60.0 243.0 303.0
% wit hin Surv iv al rate 100.0% 100.0% 100.0%
% of Total 19.8% 80.2% 100.0%
Chi-Square Tests
Crosstab
Surv iv al rate
Meninggal Hidup Total
Pneumonia Ya Count 15 22 37
Expected Count 7.3 29.7 37.0
% wit hin Surv iv al rate 25.0% 9.1% 12.2%
% of Total 5.0% 7.3% 12.2%
Tidak Count 45 221 266
Expected Count 52.7 213.3 266.0
% wit hin Surv iv al rate 75.0% 90.9% 87.8%
% of Total 14.9% 72.9% 87.8%
Total Count 60 243 303
Expected Count 60.0 243.0 303.0
% wit hin Surv iv al rate 100.0% 100.0% 100.0%
% of Total 19.8% 80.2% 100.0%
Chi-Square Tests
Crosstab
Surv iv al rate
Meninggal Hidup Total
TB paru Ya Count 0 5 5
Expected Count 1.0 4.0 5.0
% wit hin Surv iv al rate .0% 2.1% 1.7%
% of Total .0% 1.7% 1.7%
Tidak Count 60 238 298
Expected Count 59.0 239.0 298.0
% wit hin Surv iv al rate 100.0% 97.9% 98.3%
% of Total 19.8% 78.5% 98.3%
Total Count 60 243 303
Expected Count 60.0 243.0 303.0
% wit hin Surv iv al rate 100.0% 100.0% 100.0%
% of Total 19.8% 80.2% 100.0%
Chi-Square Tests
Crosstab
Surv iv al rate
Meninggal Hidup Total
Sy ok Ya Count 7 0 7
Expected Count 1.4 5.6 7.0
% wit hin Surv iv al rat e 11.7% .0% 2.3%
% of Total 2.3% .0% 2.3%
Tidak Count 53 243 296
Expected Count 58.6 237.4 296.0
% wit hin Surv iv al rat e 88.3% 100.0% 97.7%
% of Total 17.5% 80.2% 97.7%
Total Count 60 243 303
Expected Count 60.0 243.0 303.0
% wit hin Surv iv al rat e 100.0% 100.0% 100.0%
% of Total 19.8% 80.2% 100.0%
Chi-Square Tests
Crosstab
Surv iv al rate
Meninggal Hidup Total
Sepsis Ya Count 18 1 19
Expected Count 3.8 15.2 19.0
% wit hin Surv iv al rate 30.0% .4% 6.3%
% of Total 5.9% .3% 6.3%
Tidak Count 42 242 284
Expected Count 56.2 227.8 284.0
% wit hin Surv iv al rate 70.0% 99.6% 93.7%
% of Total 13.9% 79.9% 93.7%
Total Count 60 243 303
Expected Count 60.0 243.0 303.0
% wit hin Surv iv al rate 100.0% 100.0% 100.0%
% of Total 19.8% 80.2% 100.0%
Chi-Square Tests
Crosstab
Surv iv al rate
Meninggal Hidup Total
Peny akit Ya Count 4 6 10
ginjal Expected Count 2.0 8.0 10.0
% wit hin Surv iv al rate 6.7% 2.5% 3.3%
% of Total 1.3% 2.0% 3.3%
Tidak Count 56 237 293
Expected Count 58.0 235.0 293.0
% wit hin Surv iv al rate 93.3% 97.5% 96.7%
% of Total 18.5% 78.2% 96.7%
Total Count 60 243 303
Expected Count 60.0 243.0 303.0
% wit hin Surv iv al rate 100.0% 100.0% 100.0%
% of Total 19.8% 80.2% 100.0%
Chi-Square Tests
Crosstab
Surv iv al rate
Meninggal Hidup Total
Peny akit Ya Count 0 3 3
jantung Expected Count .6 2.4 3.0
% wit hin Surv iv al rate .0% 1.2% 1.0%
% of Total .0% 1.0% 1.0%
Tidak Count 60 240 300
Expected Count 59.4 240.6 300.0
% wit hin Surv iv al rate 100.0% 98.8% 99.0%
% of Total 19.8% 79.2% 99.0%
Total Count 60 243 303
Expected Count 60.0 243.0 303.0
% wit hin Surv iv al rate 100.0% 100.0% 100.0%
% of Total 19.8% 80.2% 100.0%
Chi-Square Tests
Crosstab
Surv iv al rate
Meninggal Hidup Total
Perdarahan Ya Count 7 52 59
v ar. Esof Expected Count 11.7 47.3 59.0
% wit hin Surv iv al rate 11.7% 21.4% 19.5%
% of Total 2.3% 17.2% 19.5%
Tidak Count 53 191 244
Expected Count 48.3 195.7 244.0
% wit hin Surv iv al rate 88.3% 78.6% 80.5%
% of Total 17.5% 63.0% 80.5%
Total Count 60 243 303
Expected Count 60.0 243.0 303.0
% wit hin Surv iv al rate 100.0% 100.0% 100.0%
% of Total 19.8% 80.2% 100.0%
Chi-Square Tests
Crosstab
Surv iv al rate
Meninggal Hidup Total
Ensef alopati Ya Count 41 25 66
Hepatikum Expected Count 13.1 52.9 66.0
% wit hin Surv iv al rate 68.3% 10.3% 21.8%
% of Total 13.5% 8.3% 21.8%
Tidak Count 19 218 237
Expected Count 46.9 190.1 237.0
% wit hin Surv iv al rate 31.7% 89.7% 78.2%
% of Total 6.3% 71.9% 78.2%
Total Count 60 243 303
Expected Count 60.0 243.0 303.0
% wit hin Surv iv al rate 100.0% 100.0% 100.0%
% of Total 19.8% 80.2% 100.0%
Chi-Square Tests
Crosstab
Surv iv al rate
Meninggal Hidup Total
Karsinoma Hepatoseluler Ya Count 5 29 34
Expected Count 6.7 27.3 34.0
% wit hin Surv iv al rate 8.3% 11.9% 11.2%
% of Total 1.7% 9.6% 11.2%
Tidak Count 55 214 269
Expected Count 53.3 215.7 269.0
% wit hin Surv iv al rate 91.7% 88.1% 88.8%
% of Total 18.2% 70.6% 88.8%
Total Count 60 243 303
Expected Count 60.0 243.0 303.0
% wit hin Surv iv al rate 100.0% 100.0% 100.0%
% of Total 19.8% 80.2% 100.0%
Chi-Square Tests
Crosstab
Surv iv al rate
Meninggal Hidup Total
Sindr. Hepatorenal Ya Count 2 3 5
Expected Count 1.0 4.0 5.0
% wit hin Surv iv al rate 3.3% 1.2% 1.7%
% of Total .7% 1.0% 1.7%
Tidak Count 58 240 298
Expected Count 59.0 239.0 298.0
% wit hin Surv iv al rate 96.7% 98.8% 98.3%
% of Total 19.1% 79.2% 98.3%
Total Count 60 243 303
Expected Count 60.0 243.0 303.0
% wit hin Surv iv al rate 100.0% 100.0% 100.0%
% of Total 19.8% 80.2% 100.0%
Chi-Square Tests
Crosstab
Surv iv al rate
Meninggal Hidup Total
Hematemesis Ya Count 17 62 79
Expected Count 15.6 63.4 79.0
% wit hin Surv iv al rate 28.3% 25.5% 26.1%
% of Total 5.6% 20.5% 26.1%
Tidak Count 43 181 224
Expected Count 44.4 179.6 224.0
% wit hin Surv iv al rate 71.7% 74.5% 73.9%
% of Total 14.2% 59.7% 73.9%
Total Count 60 243 303
Expected Count 60.0 243.0 303.0
% wit hin Surv iv al rate 100.0% 100.0% 100.0%
% of Total 19.8% 80.2% 100.0%
Chi-Square Tests
Crosstab
Surv iv al rate
Meninggal Hidup Total
Melena Ya Count 18 67 85
Expected Count 16.8 68.2 85.0
% wit hin Surv iv al rate 30.0% 27.6% 28.1%
% of Total 5.9% 22.1% 28.1%
Tidak Count 42 176 218
Expected Count 43.2 174.8 218.0
% wit hin Surv iv al rate 70.0% 72.4% 71.9%
% of Total 13.9% 58.1% 71.9%
Total Count 60 243 303
Expected Count 60.0 243.0 303.0
% wit hin Surv iv al rate 100.0% 100.0% 100.0%
% of Total 19.8% 80.2% 100.0%
Chi-Square Tests
Crosstab
Surv iv al rate
Meninggal Hidup Total
Ascites Ya Count 47 177 224
Expected Count 44.4 179.6 224.0
% wit hin Surv iv al rate 78.3% 72.8% 73.9%
% of Total 15.5% 58.4% 73.9%
Tidak Count 13 66 79
Expected Count 15.6 63.4 79.0
% wit hin Surv iv al rate 21.7% 27.2% 26.1%
% of Total 4.3% 21.8% 26.1%
Total Count 60 243 303
Expected Count 60.0 243.0 303.0
% wit hin Surv iv al rate 100.0% 100.0% 100.0%
% of Total 19.8% 80.2% 100.0%
Chi-Square Tests
Crosstab
Surv iv al rate
Meninggal Hidup Total
Peritonitis bakterial Ya Count 1 0 1
spontan Expected Count .2 .8 1.0
% wit hin Surv iv al rate 1.7% .0% .3%
% of Total .3% .0% .3%
Tidak Count 59 243 302
Expected Count 59.8 242.2 302.0
% wit hin Surv iv al rate 98.3% 100.0% 99.7%
% of Total 19.5% 80.2% 99.7%
Total Count 60 243 303
Expected Count 60.0 243.0 303.0
% wit hin Surv iv al rate 100.0% 100.0% 100.0%
% of Total 19.8% 80.2% 100.0%
Chi-Square Tests
Crosstab
Surv iv al rate
Meninggal Hidup Total
Gastropati Ya Count 5 34 39
HT Porta Expected Count 7.7 31.3 39.0
% wit hin Surv iv al rate 8.3% 14.0% 12.9%
% of Total 1.7% 11.2% 12.9%
Tidak Count 55 209 264
Expected Count 52.3 211.7 264.0
% wit hin Surv iv al rate 91.7% 86.0% 87.1%
% of Total 18.2% 69.0% 87.1%
Total Count 60 243 303
Expected Count 60.0 243.0 303.0
% wit hin Surv iv al rate 100.0% 100.0% 100.0%
% of Total 19.8% 80.2% 100.0%
Chi-Square Tests
Surv iv al rate
Meninggal Hidup Total
Ensef alopati grade I-II Count 5 27 32
% within Surv iv al rate 12.5% 84.4% 44.4%
% of Total 6.9% 37.5% 44.4%
grade III-IV Count 35 5 40
% within Surv iv al rate 87.5% 15.6% 55.6%
% of Total 48.6% 6.9% 55.6%
Total Count 40 32 72
% within Surv iv al rate 100.0% 100.0% 100.0%
% of Total 55.6% 44.4% 100.0%
Surv iv al rate
Meninggal Hidup Total
Ascites ringan-sedang Count 36 143 179
% wit hin Surv iv al rate 76.6% 81.3% 80.3%
% of Total 16.1% 64.1% 80.3%
berat Count 11 33 44
% wit hin Surv iv al rate 23.4% 18.8% 19.7%
% of Total 4.9% 14.8% 19.7%
Total Count 47 176 223
% wit hin Surv iv al rate 100.0% 100.0% 100.0%
% of Total 21.1% 78.9% 100.0%
85
Surv iv al rate
Meninggal Hidup Total
Tahun 2010 Count 22 90 112
% wit hin Surv iv al rat e 36.7% 37.0% 37.0%
% of Total 7.3% 29.7% 37.0%
2011 Count 22 101 123
% wit hin Surv iv al rat e 36.7% 41.6% 40.6%
% of Total 7.3% 33.3% 40.6%
2012 Count 16 52 68
% wit hin Surv iv al rat e 26.7% 21.4% 22.4%
% of Total 5.3% 17.2% 22.4%
Total Count 60 243 303
% wit hin Surv iv al rat e 100.0% 100.0% 100.0%
% of Total 19.8% 80.2% 100.0%
Crosstab
Surv iv al rate
Meninggal Hidup Total
Klasif ikasi A Count 0 15 15
CHI LD-PUGH % within Surv iv al rate .0% 8.2% 6.4%
% of Total .0% 6.4% 6.4%
B Count 4 71 75
% within Surv iv al rate 7.7% 39.0% 32.1%
% of Total 1.7% 30.3% 32.1%
C Count 48 96 144
% within Surv iv al rate 92.3% 52.7% 61.5%
% of Total 20.5% 41.0% 61.5%
Total Count 52 182 234
% within Surv iv al rate 100.0% 100.0% 100.0%
% of Total 22.2% 77.8% 100.0%
86
Chi-Square Tests
Status
Variabel Meninggal Hidup Jumlah
n % n % n %
Jenis kelamin
Laki-laki 39 65 166 68,3 205 67,7
Perempuan 21 35 77 31,7 98 32,3
Usia
< 31 tahun 1 1,7 9 3,7 10 3,3
31 – 40 tahun 3 5 18 7,4 21 6,9
41 – 50 tahun 15 25 64 26,3 79 26,1
51 – 60 tahun 19 31,7 85 35 104 34,3
61 – 70 tahun 15 25 44 18,1 59 19,5
> 70 tahun 7 11,7 23 9,5 30 9,9
Etiologi
Virus
HBV 35 58,3 149 61,3 184 60,7
HCV 8 13,3 47 19,3 55 18,2
HBV dan HCV 4 50 13 27,7 17 30,9
Non Virus
NAFL 3 5 18 7,4 21 6,9
Lain-lain 18 30 41 16,9 59 19,5
Klasifikasi CHILD-PUGH
A 0 0 15 8,2 15 6,4
B 4 7,7 71 39 75 32,1
C 48 92,3 96 52,7 144 61,5
Komplikasi
Perdarahan varises esophagus 7 11,7 52 21,4 59 19,5
Ensefalopati hepatikum 41 68,3 25 10,3 66 21,8
Karsinoma hepatoseluler 5 8,3 29 11,9 34 11,2
Sindroma hepatorenal 2 3,3 3 1,2 5 1,7
Hematemesis 17 28,3 62 25,5 79 26,1
Melena 18 30 67 27,6 85 28,1
Ascites 47 78,3 177 72,8 224 73,9
90
Komorbid
Efusi pleura 3 5 35 14,4 38 12,5
Pneumonia 15 25 22 9,1 37 12,2
TB paru 0 0 5 2,1 5 1,7
Syok 7 11,7 0 0 7 2,3
Sepsis 18 30 1 0,4 19 6,3
Penyakit ginjal 4 6,7 6 2,5 10 3,3
Penyakit jantung 0 0 3 1,2 3 1
Ensefalopati Hepatikum
Grade I-II 5 12,5 27 84,4 32 44,4
Grade III-IV 35 87,5 5 15,6 40 55,6
Ascites
Ringan-sedang 36 76,6 143 81,3 179 80,3
Berat 11 23,4 33 18,8 44 19,7
Tahun
2010 22 36,7 90 37 112 37
2011 22 36,7 101 41,6 123 40,6
2012 16 26,7 52 21,4 68 22,4
91
Variabel p
Usia 0,193
PPT 0,000
Tabel deskriptif
Variabel N Mean SD
Status
Klasifikasi
Meninggal Hidup Jumlah p
CHILD-PUGH
n % n % n %
A 0 0 15 8,2 15 6,4 < 0,001
B 4 7,7 71 39 75 32,1
C 48 92,3 96 52,7 144 61,5
Dari uji Chi Square antara Klasifikasi CHILD-PUGH terhadap status survival
didapatkan nilai p = < 0,001, karena p < 0,05 maka dapat disimpulkan terdapat
hubungan yang signifikan antara klasifikasi CHILD-PUGH dengan status survival.
93
Survival Rate
Usia Meninggal Hidup p
n (60) % n (243) %
< 31 1 1,7 9 3,7 0,761£
31 – 40 3 5 18 7,4
41 – 50 15 25 64 26,3
51 – 60 19 31,7 85 35
61 – 70 15 25 44 18,1
> 70 7 11,7 23 9,5
Keterangan :
£
Pearson Chi Square
Survival Rate
Comorbid Meninggal Hidup p
n (60) % n (243) %
Efusi pleura 3 5 35 14,4 0,049*£
Pneumonia 15 25 22 9,1 0,001*£
TB paru 0 0 5 2,1 0,587¥
Syok 7 11,7 0 0 0,000*¥
Sepsis 18 30 1 0,4 0,000*¥
Penyakit ginjal 4 6,7 6 2,5 0,114¥
Penyakit jantung 0 0 3 1,2 1,000¥
Keterangan :
¥
Fisher’s Exact Test
Survival Rate
Komplikasi Meninggal Hidup p
n (60) % n (243) %
Perdarahan varises Esofagus 7 11,7 52 21,4 0,088£
Ensefalopati Hepatikum 41 68,3 25 10,3 0,001*£
Karsinoma Hepatoseluler 5 8,3 29 11,9 0,429£
Sindroma Hepatorenal 2 3,3 3 1,2 0,258¥
Hematemesis 17 28,3 62 25,5 0,656£
Melena 18 30 67 27,6 0,708£
Ascites 47 78,3 177 72,8 0,385£
Peritonitis bacterial spontan 1 1,7 0 0 0,198¥
Gastropati HT Porta 5 8,3 34 14 0,241£
Keterangan :
Identitas
NIM : 22010110110031
Nomor HP : 085737105588
E-mail : tuty.marselina@rocketmail.com