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Article Received on: 20/06/11 Revised on: 25/07/11 Approved for publication: 09/08/11
*Email: talhajawaid78@gmail.com
ABSTRACT
High blood pressure, termed "hypertension," is a condition that afflicts almost 1 billion people worldwide and is a leading cause of morbidity
and mortality. More than 20% of Americans are hypertensive, and one-third of these Americans are not even aware they are hypertensive.
Therefore, this disease is sometimes called the "silent killer." This disease is usually asymptomatic until the damaging effects of hypertension
(such as stroke, myocardial infarction, renal dysfunction, visual problems, etc.) are observed. Hypertension is a major risk factor for coronary
artery disease and "heart attacks," which may require coronary artery bypass surgery.
This study describes the antihypertensive activities present in herbal plants. Herbal medicine has made many contributions to commercial
drug preparations manufactured today herbal medicine has been losing ground to new synthetic medicines touted by scientists and physicians
to be more effective and reliable.
Keywords: Hypertension, Medicinal plants, Antihypertensive herbal plants.
INTRODUCTION
Cardiovascular disease (CVD) is the leading cause of can bring blood pressure values into the normal range;
death worldwide. Hypertension is the most common however, if lifestyle changes are not maintained,
cardiovascular disease and a major public health problem hypertension will probably return. Secondary
in both developed and developing countries. The disease hypertension has an organic cause (i.e., kidney disease,
affects both sexes and more and more patients are pregnancy) and must be evaluated and monitored by a
turning up at younger ages. Hypertension is the leading physician since the underlying cause must also be
member of the group of so called “non-communicable addressed. It often takes some time to find the best
diseases” (NCD) and a leading Contributory cause of treatment for pulmonary hypertension.
death worldwide.4 It is believed that hypertension CONCLUSION
contributes about 57 per cent towards all deaths from Herbal medicines are being used by about 80% of the
strokes and 24 per cent towards all deaths from coronary world population particularly in the developing countries
artery disease. for the primary health care. The natural products should
Hypertension is reported to be the fourth contributor to be considered as the best in primary health care because
premature death in developed countries and the seventh of better cultural acceptability, safety, potent,
in developing countries. High blood pressure is the most inexpensive and lesser side effects. Several herbal
common and responds well to lifestyle changes, such as medicines and supplements have been studied as
losing weight, dietary changes, exercise, and stress potential therapeutic agents in the management of
reduction. Natural treatment of essential hypertension hypertension and its related complications.
REFERENCES
1. Benowitz N.L, Katzung BG, editor, Antihypertensive agents. hypertensive rats. The Journal of Nutritional Biochemistry
Basic & Clinical Pharmacology, 2001; 155-80. 2009; 20: 866-875.
2. Gilani AH, Jabeen Q, Ghayur MN, Janbaz KH, Akhtar MS: 8. Sharifi AM, Darabi R, Akbarloo N: Study of Antihypertensive
Studies on the Antihypertensive, Antispasmodic, mechanism of Tribulus terrestris in 2k1c hypertensive rats:
Bronchodilator and Hepatoprotective activities of the Carum Role of tissue ace activity. Life Sciences, 2003; 73: 2963-2971.
copticum seed extract. Journal of Ethnopharmacology 9. Yeh C-T, Huang W-H, Yen G-C: Antihypertensive effects of
2005,98:127-135. Hsian-tsao and its active compound in spontaneously
3. Somova LI, Shode FO, Ramnanan P, Nadar A: hypertensive rats. The Journal of Nutritional Biochemistry
Antihypertensive, Antiatherosclerotic and Antioxidant activity 2009; 20: 866-875.
of triterpenoids isolated from Olea europaea, subspecies 10. Tahraoui A, El-Hilaly J, Israili ZH, Lyoussi B:
africana leaves. Journal of Ethnopharmacology, 2003 ;84:299- Ethnopharmacological survey of plants used in the traditional
305. treatment of Hypertension and Diabetes in south-eastern
4. Maghrani M, Zeggwagh N-A, Michel J-B, Eddouks M: morocco (errachidia province). Journal of Ethnopharmacology,
Antihypertensive effect of Lepidium sativum l. In spontaneously 2007;110: 105-117.
hypertensive rats. Journal of Ethnopharmacology, 2005 ;100: 11. Lin S-Y, Wang C-C, Lu Y-L, Wu W-C, Hou W-C: Antioxidant,
193-197. Anti-semicarbazide-sensitive amie oxidase, and Anti-
5. Kwan C-Y, Chen C-X, Deyama T, Nishibe S: Endothelium- hypertensive activities of geraniin isolated from Phyllanthus
dependent Vasorelaxant effects of the aqueous extracts of the urinaria. Food and Chemical Toxicology, 2008; 46: 2485-249.2
Eucommia ulmoides oliv. Leaf and bark: Implications on their 12. Oh H, Kang D-G, Lee S, Lee H-S: Angiotensin converting
antihypertensive action. Vascular Pharmacology, 2003;40: 229- enzyme inhibitors from Cuscuta japonica choisy. Journal of
235 Ethnopharmacology, 2002; 83: 105-108.
6. Vergara-Galicia J, Ortiz-Andrade R, Castillo-España P, Ibarra- 13. Hernández-Abreu O, Castillo-España P, León-Rivera I, Ibarra-
Barajas M, Gallardo-Ortiz I, Villalobos-Molina R et al: Barajas M, Villalobos-Molina R, González-Christen J et al:
Antihypertensive and Vasorelaxant activities of Laelia Antihypertensive and Vasorelaxant effects of tilianin isolated
autumnalis are mainly through calcium channel blockade. from Agastache mexicana are mediated by no/cgmp pathway
Vascular Pharmacology, 2008; 49: 26-31. and potassium channel opening. Biochemical
7. Yeh C-T, Huang W-H, Yen G-C: Antihypertensive effects of Pharmacology,2009;78: 54-61.
Hsian-tsao and its active compound in spontaneously 14. Gasparotto Junior A, Gasparotto FM, Lourenço ELB, Crestani
S, Stefanello MEA, Salvador MJ et al: Antihypertensive effects