Professional Documents
Culture Documents
1) N.R is a patient with gout has recently increase in blood pressure, what antihypertensive not to be
taken
Ocular Symptoms- Conjunctival itching, conjunctival watering, Redness, Burning, Clear and watery
discharge
a-Stock’s law
c-Noyes whitney(dissolution)
d-Raoult’s law
a-extra pyramidal
b-increase prolactin
c-postural hypotension
d all of above
Tips : orthostatic hypotension is most common in elderly with low potency (FGA) first generation
antipsychotics ( chlorpromazine, methotrimeprazine)
5-photosenstivity shows
6-lung cancer
a-influenced by environment
a-oily stools
d-should exercise
Dose Adults : > 19 y – 1ml im * 3 at 0 , 1, 6 months OR Day (0, 7, 21, 365 days)
9-a manager is feeling his staff doesn’t give enough care for patients in her multicultural (divert)
community. Should do all except
a-give courses
b-hire multi ethnic staff
a-retrovirus
b-adenovirus
c-mycobacterium
Tips: Isotonic :- The solute concentration is the same on both sides of the membrane.(misbhah 34-6)
a-baclofen
b-dantrolene
c-suxamethonium
d-pancronium
15-a nurse calls about a patient having fentanyl patch that falls during bathing and destroyed, the refill
stay 2 days after.
17-elder patient switched to oral liquid solution instead of oral pills, the cause is
a-dysphagia
b-cognitive disorder
c-parkinson disorder
d-allergy
c-turbid fluid
20-a,b,c,d,e are patients having different drugs. order them from the most important to the least to be
reported to the dose
a 1 70% 10%
b 2 90% 5%
c 3 50% 10%
d 4 70% 25%
e 5 10% 90%
A- b-a-d-c-e
B- b-a-c-d-e
C- a-c-b-e-d
22-isotonic solution
d-1000 mg twice
29-woman in her 24 week of pregnancy suffer from polipteal pain(pain in the back knee)which is the
sign of deep vein thrombosis, she should take
a-ASA
b-clopidogrel
d-warfarin
e-dalteparin
a-insulin
b-metformin
c-metformin+glypiride
a-appt
b-thromboplastin time
d-given subcutaneously
a-candida
b-smoking cessation
c-xerostamia
d-diaper rash
e-vaccination schedules
b-minocycline
c-erythromycin
d-ciprofloxacin
e-tetracycline
Tips : patient with acne and resistant to oral antibiotics , use isotretinoin
b-release information to a concerned party if the aim is to prevent him from committing suicide
38-a lady uses sun block with SPF 15, that’s means
d-sun burn will occur 15 times less if sun block was not applied
a-partnership
b-corporation
c-co operative
d-franchise
e-sole ownership
mixed with 8gm of 0.2%zinc ointment and 14gm ointment base, what is the final conc of zinc
0.025 gm in 10gm and 0.016 gm in 8 gm . Now ointment base is 14 gm so total base is 32 gm and med is
0.041gm, find out for 100gm, and you will get the %
42-how long it will take for a drug with k=0.0005day -1 to reach 10%
(4606 days)
50-complications of diabetes
a-o/w is hydrophilic
c-w/o is hydrophopic
a-muscle pain&cramps
b-muscle weakness
c-colored urine ("tea-colored", due to the presence of myoglobin)
d-odor in urine
55-When a pharmaceutical company starts a research for a new medication, it has to protect her rights
by making registration for : 2007
a) Logo
b) Copy Right
c) Trade Name
d) Patency
e) Brand Name
56- A patient has dark urine, and muscle pains (rhabdomyolysis) . Which of the following drug may be
patient on?
A-Metronidazole
B-Atorvastatin
C- Rifampin
D-Bismuth
E-Lithium
a-herpes simplex
b-herpes zoster
c-treponema
d-nisseria
e-HIV
a- Lung
b- Kidney
d- Spleen
e- Liver
60-pharmacist tell the pharmacy assistant to council a patient about antibiotic, this is against
a. cisplatin b.cyclophosphamide
67-treatment of scabies
c-leave 8-12hrs
72-for HPLC
74-which is photosensitive
75-epitetracycline-----------tetracycline (epimerization)
78-drug which is extensively metabolized and there is renal failure, which is affected
a-systemic clearance
d-protein binding
79-in renal failure, all are true except (increase in albumin level in blood)
84-which passes B.B.B the least (choose the least partition coefficient)
Nitrogenous base - Adenine, guanine, cytosine, thymine (only in DNA), uracil (only in RNA)
Phosphates - One to three, two of which are usually hydrolyzed to provide the energy to attach the
nucleotide and form the phosphodiester bond
a-activated by light
b-found in large no. than rods
Tips :The rods are more numerous, some 120 million, and are more sensitive than the cones.
c. appetite d. sleep
in blood
(loratidine)
Tips: essential amino acids are the components of proteins that make them essential in the diet.
(levigation)
98-cotrimoxazole
a-PABA structure
b-THFR inhibitor
(vancomycin)
(epinephrine)
101-for choosing appropriate dose of antibiotic we should put in consideration all except
(pressure atrophy)
104-i.v infusion
a-intermittent or continuous
b-steady state
b-cats in environment
c-hypertention
Drugs: beta blockers, NSAIDS\ASA\COX2 inhibitors, tartrazine, sulfites, radio contrast media
a-gonorhea
b-hepatitis
c-herpes
d-botulism
Tips: It is fatal disease caused by a toxin produced by the bacterium Clostridium botulinum.
a-microcytic
Tips: Better dosing flexibility and outcomes with gum/patch combination therapy {CTC-7 page 184}
109-treatment of epilepsy by
Tips: In epilepsy treatment potentiation of GABA activity required (Tiagabine, Topiramate) and also
reduces NMDA receptor activation.
a-osteoporosis
b-diabetes
c-hypertension
d-increase prolactin
a-amoxicillin
b-etidronate
c-cefuxetine acetate
d-norfloxacin
b-dicalcium phosphate
c-magnesium stearate
114-a female has a prescription for corticosteroids cause she suffer from inflammatory bowel disease,
the concern of the pharmacist to ask her if she suffers from all except
a-diabetes mellitus
b-hypertension
c-breast cancer
d-infection
e-osteoporosis
115-infliximab is used in
a-ashma
b-glomuronephritis
Tips: infliximab is effective in inducing and maintaining remmision in patients with moderate to severe
Crohn’s disease (best with combination therapy with azathioprine) CTC-7 reference
a. interferon
b. amantadin
c. acyclovir
d. infliximab
e.etaneracept
Tips: Peg Interferon alfa-2a used in chronic hepatitis B {180 microgram once weekly for 48 weeks}
a. flutamide
b. finasteride
c. other drugs
a. hypokalemia
b. decrease gluconeogenesis
c.peptic ulcer
d. inhibit pit. Function
c. PAPS d. UDP
e.acetyl co-enzyme A
a. penicillin
b.warfarin
c. benzodiazepin
d. glycosides (digoxin)
c. lithium d. topiramate
129. Which age group shows the highest clearance for theophylline?
a) 1-2 weeks
b) 4-6 weeks
c) 2-6 years
d) 18-25 years
e) 40-65 years
a) To have negative results with people who don't have the disease
Sensitivity (also called the true positive rate, or the recall in some fields)
(e.g., the percentage of sick people who are correctly identified as having the condition).
Tips :Specificity (also called the true negative rate) measures the proportion of negatives that are
correctly identified as such (e.g., the percentage of healthy people who are correctly identified as not
having the condition).
131. vit. D toxicity (Hypervitaminosis D) ?
An excess of vitamin D causes abnormally high levels of calcium in the blood (hypercalcemia).
This can severely damage the kidneys, soft tissues, and bones over time. Constipation, Decreased
appetite (anorexia),
Tips: The Wilcoxon signed-rank test is a non-parametric statistical hypothesis test used
when comparing two related samples, matched samples, or repeated measurements on a single sample
to assess whether their population mean ranks differ (i.e. it is a paired difference test)
Circular DNA is DNA that forms a closed loop and therefore has no free ends. Examples include:
1- sulfa allergy
2- renal impairement
136- Css
Tips: Steady State concentration is eventually achieved when a drug is administered at a constant rate.
At steady state, rate in = rate out. Steady state is achieved after 4 t1/2
(94% of steady state concentration (Css)) to 5 t1/2 (97 % of Css). Loading dose is usually given to get
plasma concentration to steady state quickly
thus decrease the bronchial swelling and secretions that in turn allows better airflow because of
reduced airway obstruction.
Often inhaled steroids are administered since they have fewer side effects than systemic (oral) steroids.
a. ↑ bioavailability
139- patient with jaundice , lower limb. Oedema , abdomin distension . which describes ascitis?
a. jaundice
c. abdominal distension
Abdominal distension
Weight gain
b. estrogen
c. progesterone
c. FSH d. progesterone
the “hydrophilic” (water-attracting) mucoid or mucin layer of the tear film is laid down
is a selective and competitive receptor antagonist of leukotriene D4 and E4 (LTD4 and LTE4)
147- NH2-----CooH ?
a.Actively secreted
b. filtered only
c. partially reabsorbed
d. a & b
149- thixotropy is ;
a. shear thickening
b. shear thinning
Tips: Pseudoplastic flow ( Gel ------------to convert---------- solution)
a. crystal form
b. amorphous form
151- phenytoin metabolite ( given structure ) due to conjugation with ? with glucuronic acid
152- Oxygen toxicity can cause seizures in the brain which is linked directly to the inhibition of:
a) monoamine oxidase
b) catechol-orthomethyl transferase
c) lactate dehydrogenase
d) glutathione reductase
Metabolic degradation
155- manager of pharmacy who when there’s a problem , he doesn’t council his assistants . this type is
called :
156- this structure is for antibiotic . Given against gram –ve that can be used also in :
a.M.S.
b.endocarditis
c.hyperthyroidism
a. 1 b. 2 c. 3 d. 4
a. thalassemia
b. spherocytosis
c. G6PD. Dif.
IV 130
Oral 38
I.P 38
So this drug is
b. ………………… by gut
a.nefidipine b. verapamil
c.diltiazem d. b & c
Tips : The sedimentation rate in a suspension can be determined by the Stoke's equation.
164- which drug depends in its action on the presence of thrombin factor Ш
a.heparin
b.warfarin
c.aspirin
a. Alzheimer b. parkinsonism
a. meningococcal
b. pneumococcal
c. dephteria
d.pertusis
a. α tocopherol
b. β tocopherol
c. γ tocopherol
d. δ tocopherol
MELANOMA, one of the deadliest forms of skin cancer, most often appears as an asymmetrical,
size over time. It may begin as aflat spot and become more elevated. In rare instances, it
DYSPLASTIC NEVI (atypical moles) are unusual benign moles that may resemble melanoma.
People who have them are at increased risk of developing single or multiple melanomas.
The higher the number of these moles someone has, the higher the risk; those who have 10 or more
have 12 times
the risk of developing melanoma compared to the general population. Dysplastic nevi are found
significantly more