1) The study examined the records of 757 HIV-positive patients at an outpatient treatment center in Dakar between 2008-2012 and found that 76 (10%) of these patients had tuberculosis, indicating a high prevalence of TB/HIV co-infection.
2) The average age of patients with TB/HIV co-infection was 42.5 years and most had HIV-1. Nearly 40% reported a history of tuberculosis and 17 patients were malnourished.
3) Pulmonary tuberculosis was the most common form, accounting for 72.4% of cases. Anemia and severe immunosuppression were common findings. The lethality rate among those with TB/HIV co-infection was 7
1) The study examined the records of 757 HIV-positive patients at an outpatient treatment center in Dakar between 2008-2012 and found that 76 (10%) of these patients had tuberculosis, indicating a high prevalence of TB/HIV co-infection.
2) The average age of patients with TB/HIV co-infection was 42.5 years and most had HIV-1. Nearly 40% reported a history of tuberculosis and 17 patients were malnourished.
3) Pulmonary tuberculosis was the most common form, accounting for 72.4% of cases. Anemia and severe immunosuppression were common findings. The lethality rate among those with TB/HIV co-infection was 7
1) The study examined the records of 757 HIV-positive patients at an outpatient treatment center in Dakar between 2008-2012 and found that 76 (10%) of these patients had tuberculosis, indicating a high prevalence of TB/HIV co-infection.
2) The average age of patients with TB/HIV co-infection was 42.5 years and most had HIV-1. Nearly 40% reported a history of tuberculosis and 17 patients were malnourished.
3) Pulmonary tuberculosis was the most common form, accounting for 72.4% of cases. Anemia and severe immunosuppression were common findings. The lethality rate among those with TB/HIV co-infection was 7
Ambulatory Treatment Center in Dakar. Ka D1, Ngom Guéye NF2, Fall N1, Touré-Badiane NO1, Diop N1, Batista G1, Ndiaye K1, Ndour CT1, Seydi M1, Faye MA1.
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Abstract
To determine the prevalence of tuberculosis and describe its epidemiological, clinical,
paraclinical, and therapeutic characteristics and its outcome in patients with HIV. This retrospective, descriptive, and analytical study examined the records of patients with HIV at our outpatient treatment center and selected those who were antiretroviral-naive and presented tuberculosis between January 2008 and December 2012. Among a total of 757 HIV-positive patients, 76 had tuberculosis, for a prevalence of 10 %. The sex ratio of 1.23 favored men. The average age was 42.5 years (range: 25 to 69 years. Nearly all these patients (71 cases) had HIV-1. A history of tuberculosis was reported by 39.5 %. Seventeen patients were malnourished. Management included chemoprophylaxis with cotrimoxazole for 64 patients. The pulmonary form predominated (72.4 %). Among these forms, there were 34 cases of negative microscopy tuberculosis and 21 cases of positive microscopy tuberculosis. The extrapulmonary forms (21 cases) were dominated by tuberculosis in the lymph nodes (11 cases), the pleura (7), pericardium (2), and peritoneum (1). Anemia was found in 44 patients. Severe immunosuppression was noted in 90 %, with CD4+ cell counts <350/mm3. Lethality was 7.9 %. TB/HIV coinfection is a major public health problem in Africa. Better coordination of activities in support of programs for tuberculosis and HIV/AIDS are needed.