Professional Documents
Culture Documents
The immune system normally guards against germs like bacteria and
viruses. When it senses these foreign invaders, it sends out an army of
fighter cells to attack them.
Normally, the immune system can tell the difference between foreign cells
and your own cells.
ADVERTISEMENT
Why does the immune system attack the body?
Doctors don’t know exactly what causes the immune-system misfire. Yet
some people are more likely to get an autoimmune disease than others.
1. Type 1 diabetes
The pancreas produces the hormone insulin, which helps regulate blood
sugar levels. In type 1 diabetes mellitus, the immune system attacks and
destroys insulin-producing cells in the pancreas.
High blood sugar results can lead to damage in the blood vessels, as well
as organs like the heart, kidneys, eyes, and nerves.
In rheumatoid arthritis (RA), the immune system attacks the joints. This
attack causes redness, warmth, soreness, and stiffness in the joints.
3. Psoriasis/psoriatic arthritis
Skin cells normally grow and then shed when they’re no longer needed.
Psoriasis causes skin cells to multiply too quickly. The extra cells build up
and form inflamed red patches, commonly with silver-white scales of
plaque on the skin.
4. Multiple sclerosis
Multiple sclerosis (MS) damages the myelin sheath, the protective coating
that surrounds nerve cells, in your central nervous system. Damage to the
myelin sheath slows the transmission speed of messages between your
brain and spinal cord to and from the rest of your body.
This damage can lead to symptoms like numbness, weakness, balance
issues, and trouble walking. The disease comes in several forms that
progress at different rates. According to a 2012 study , about 50 percent
of people with MS need help walking within 15 years after the disease
starts.
Joint pain, fatigue, and rashes are among the most common symptoms.
Crohn’s disease can inflame any part of the GI tract, from the mouth
to the anus.
Ulcerative colitisaffects only the lining of the large intestine (colon)
and rectum.
7. Addison’s disease
Symptoms include weakness, fatigue, weight loss, and low blood sugar.
8. Graves’ disease
Graves’ disease attacks the thyroid gland in the neck, causing it to
produce too much of its hormones. Thyroid hormones control the body’s
energy usage, known as metabolism.
9. Sjögren’s syndrome
This condition attacks the glands that provide lubrication to the eyes and
mouth. The hallmark symptoms of Sjögren’s syndrome are dry eyes and
dry mouth, but it may also affect the joints or skin.
Myasthenia gravis affects nerve impulses that help the brain control the
muscles. When the communication from nerves to muscles is impaired,
signals can’t direct the muscles to contract.
The most common symptom is muscle weakness that gets worse with
activity and improves with rest. Often muscles that control eye
movements, eyelid opening, swallowing, and facial movements are
involved.
People with celiac disease can’t eat foods containing gluten, a protein
found in wheat, rye, and other grain products. When gluten is in the small
intestine, the immune system attacks this part of the gastrointestinal tract
and causes inflammation.
A 2015 study noted that celiac disease affects about 1 percent of people
in the United States. A larger number of people have reported gluten
sensitivity, which isn’t an autoimmune disease, but can have similar
symptoms like diarrhea and abdominal pain.
ADVERTISEMENT
Autoimmune disease symptoms
The early symptoms of many autoimmune diseases are very similar, such
as:
fatigue
achy muscles
swelling and redness
low-grade fever
trouble concentrating
numbness and tingling in the hands and feet
hair loss
skin rashes
Individual diseases can also have their own unique symptoms. For
example, type 1 diabetes causes extreme thirst, weight loss, and fatigue.
IBD causes belly pain, bloating, and diarrhea.
With autoimmune diseases like psoriasis or RA, symptoms may come and
go. A period of symptoms is called a flare-up. A period when the
symptoms go away is called remission.
The antinuclear antibody test (ANA) is often one of the first tests that
doctors use when symptoms suggest an autoimmune disease. A positive
test means you may have one of these diseases, but it won’t confirm
exactly which one you have or if you have one for sure.
Eating a well-balanced diet and getting regular exercise may also help
you feel better.
Autoimmune diseases are more common in women, and they often run in
families.
Blood tests that look for autoantibodies can help doctors diagnose these
conditions. Treatments include medications to calm the overactive
immune response and bring down inflammation in the body.
12 sources
v FEEDBACK:
READ MORE
more.
READ MORE
READ MORE
Lupus and RA are both autoimmune diseases and share many symptoms,
so misdiagnosis isn’t uncommon. Autoimmune disease occurs when your
immune system…
READ MORE
Autoimmune Hepatitis
Medically reviewed by Daniel Murrell, MD
READ MORE
The Difference Between Crohn’s, UC, and IBD
Medically reviewed by Deborah Weatherspoon, PhD, RN, CRNA
READ MORE
READ MORE
READ MORE
Understanding Psoriasis in Children: Symptoms,
Treatments, and More
Medically reviewed by Debra Sullivan, PhD, MSN, RN, CNE, COI
READ MORE
READ MORE
SUBSCRIBE
Your privacy is important to us
m v z
Copyright © 2005 - 2019 Healthline Media. All rights reserved. Our content does not
constitute a medical consultation. See a certified medical professional for diagnosis.
Privacy Policy.