Introduction to Bioelectronics and Bioinformation Engineering

Long Quiz 3 – BIOELECTRONICS: Electronics and Biosensors SET A

School of Chemical Engineering and Chemistry

Multiple choice: Choose the best answer.

1. The following are descriptions of biomaterials except

a. biomaterials are used in medical devices. c. biomaterials should be compatible to biosystems.
b. biomaterials may be synthetic or natural. d. biomaterials are biodegradable.

2. Defined as the rate of flow of electric charge through a conductor per unit time.
a. Voltage c. Power
b. Potential d. Current

3. The unit of electric potential is given in

a. Volt c. Joule
b. Ampere d. Watt

4. The opposition to the flow of electrons in an electric circuit.

a. Voltage c. Potential
b. Resistance d. Current

5. It represents the amount of energy dissipated by a component

a. current c. work
b. power d. potential

6. It is the rate of transfer of energy (work) per unit time.

a. Voltage c. Current
b. Potential d. Power

7. A device that measures current in a circuit

a. ammeter c. transistor
b. voltmeter d. potentiometer

8. The unit of resistivity is given as

a. ohm/meter c. ohm -meter
b. meter - second d. ohm/second

9. For a bioelectronic system, it is required that

a. it is large enough to function efficiently inside the cell.
b. there is biocompatibility of the device.
c. there is electronic coupling and communication between the biomolecules and biomaterial.
d. it is miniaturized so that it can promote stability of the system.

10. Measure of a material’s resistance to current flow.

a. potential difference c. conductivity
b. voltage regulation d. resistivity

11. An electrical component that limits or regulates the flow of electrical current within a circuit.
a. transistors c. detector
b. regulator d. resistor

12. A high resistivity indicates a material that readily

a. inhibits movement of electrical charge c. spreads out flow of electrical charge
b. allows movement of electrical charge d. prevents spread out of ionic charge

13. Spectrophotometers measures the amount of emitted, absorbed or transmitted

a. vibrational energy c. electric energy
b. rotational energy d. electromagnetic energy

14. In the Clark oxygen electrode, which is the working electrode where reduction of oxygen occurs?
a. Pt anode c. Pt cathode
b. Ag/AgCl anode d. Ag/AgCl cathode

15. The amount of current produced in the redox reaction inside the Clark electrode is _______ proportional to the rate of
electrons transferred from ___________.
a. inversely, O2 to H2O c. directly, O2 to H2O
b. inversely, H2O to O2 d. directly, H2O to O2

16. Common type of monochromator used in spectrophotometers

a. prism c. silica
b. quartz glass d. tungsten filament

17. Measures the amount of current flowing through an electrochemical cell when a constant potential is applied to the
electrodes.
a. Votammetry c. Galvanometer
b. Spectrophotometry d. Amperometry

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 Introduction to Bioelectronics and Bioinformation Engineering
Long Quiz 3 – BIOELECTRONICS: Electronics and Biosensors SET A

18. The concentration of glucose is indicated by the

a. increase in partial pressure of hydrogen c. increase in partial pressure of oxygen
b. decrease in partial pressure of hydroxide d. decrease in partial pressure of oxygen

19. The glucose biosensor makes use of the enzyme

a. glucose aminidase c. glucose hydrolase
b. glucose phosphorylase d. glucose oxidase

20. The amount of oxygen consumed in the reaction is measured by

a. increase in partial pressure of hydrogen c. increase in partial pressure of oxygen
b. decrease in partial pressure of hydroxide d. decrease in partial pressure of oxygen

21. Defined as the potential difference between the two sides of the membrane of a nerve cell when the cell is not
conducting an impulse
a. action potential c. membrane potential
b. equilibrium potential d. resting potential

22. A type of evoked potential which allows the study of the functioning of nerve, spinal cord and the brain.
a. somatosensory evoked potential c. brainstem auditory evoked potential
b. visual evoked potential d. sensory nerve action potential

23. It represents electrical activity in the brain.

a. brain potential c. brain impulse
b. brain wave d. brain damage

24. Device used to detect and measure patterns and relative strengths of electrical activity emanating from the brain.
a. Computed Tomography c. Positron Emission Tomography
b. Electroencephalography d. Magnetic Resonance Imaging

25. Which of the following is an application of artificial intelligence

a. Data modeling c. Mathematical paradigm of response to stimuli
b. Data processing d. Physical paradigm of response to stimuli

26. Deals with the behavior, precise control and manipulation of fluids that are geometrically constrained to a small scale.
a. Fluid mechanics c. Microfluidics
b. Hydraulics d. Mass transfer

27. The output transduced signal that is measured is light signal for this type of biosensors.
a. Resonant Biosensor c. Ion-sensitive Biosensor
b. Thermal-detection Biosensor d. Electrochemical Biosensor

28. It is the basic technique used to define the shape of micromachined structures.
a. Etching c. Thin film deposition
b. Photolithography d. Doping

29. Neurons communicate via chemical and electrical synapses, in a process known as
a. neurotransmission. c. synaptic transmission.
b. Neurotransmitter. d. neurosynapsis.

30. A propagating electrical signal that is generated by exploiting the electrically excitable membrane of the neuron
a. Resting potential c. Repolarization
b. Action potential d. Upshoot phase

31. Device which measures emissions from radioactively labeled chemicals that have been injected into the bloodstream
and uses the data to produce two- or three-dimensional images of the distribution of the chemicals throughout the brain
and body.
a. Computed Tomography c. Positron Emission Tomography
b. Electroencephalography d. Magnetic Resonance Imaging

32. EEG recording system consists of

a. electrodes with conductive media c. analog to digital converter
b. amplifiers with filters d. radio frequency coils

33. It measures the change in heat either in the form of absorption from or radiation of heat to the system as result of a
chemical reaction
a. Resonant Biosensor c. Ion-sensitive Biosensor
b. Thermal-detection Biosensor d. Electrochemical Biosensor

34. It is a physical or chemical process used to produce thin films with high-purity, high-performance solid materials.
a. Etching c. Thin film deposition
b. Photolithography d. Doping

35. The following are characteristics of MRI except

a. MRI uses X-rays or radioactive materials.
b. MRI provides detailed view of the brain in different dimensions.
c. MRI is safe, painless, non-invasive.
d. Patients can eat or drink anything before the procedure.

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 Introduction to Bioelectronics and Bioinformation Engineering
Long Quiz 3 – BIOELECTRONICS: Electronics and Biosensors SET A

36. It is a device used to label specific drugs or analogues of biomolecules with small amounts of radioactivity.
a. PET scanner c. radiotracer
b. PET sensor d. cyclotron

37. How does PET detect compounds which accumulate in the brain?
a. through brain signals.
b. through radioactivity.
c. through electromagnetic energy
d. through x-rays.

38. Which is true about CT or CAT scan?

a. uses radio waves to produce high-quality two dimensional images of brain structures
b. it involves the use of a radioactive material.
c. It creates images of the brain structure but not its function.
d. it can provide functional view of the brain.

39. In this type of biosensors an acoustic wave transducer is coupled with antibody (bio-element).
a. Resonant Biosensor c. Ion-sensitive Biosensor
b. Thermal-detection Biosensor d. Electrochemical Biosensor

40. Involves the modification of properties of the device layer, by ion implantation creating a low and controllable level of
atomic impurity.
a. Etching c. Thin film deposition
b. Photolithography d. Doping

Problem Solving:
1. A conductor measures 3 cm in diameter and 40 cm long with a resistivity of 0.8·m. For a voltage of
2.0kV during defibrillation, calculate the power dissipated. (10 points)

2. What is the resistance value of a resistor with a color band pattern as follows: (5 points)
BROWN, RED, ORANGE, SILVER

Color Number % Tolerance

Brown 1
Red 2
Orange 3
Yellow 4
Green 5
Gold -1 5
Silver -2 10
colorless 20

3. Five resistors R1 to R5 are connected in parallel. All the resistances R1 to R5 are 4.70k. What is the
total resistance of this combination? (5 points)

4. A dc circuit contains three resistors in parallel R1 = 22, R2 = 47 and R3 = 68 across a battery that
supplies a voltage V = 3.0V. Find the power dissipated by each resistance. What is the total dissipated
wattage? (10 points)

5. Suppose all three resistors have values of 100 (two resistors in series and in parallel with the third
resistor) and that I1 = 2.0A and I2 = 1.0A. What is the battery voltage? (10 points)

6. Give one (1) technique on coupling the “bio”-element with the sensor element. Discuss the technique
briefly. You may use figures in discussing your answer. ( 5 points )

7. Enumerate the five types of biosensors and describe each. ( 10 points )

8. Give one (1) technique in biosensor fabrication. Discuss the technique briefly. (5 points)

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