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EAMON AALIPOUR

eamon.aalipour@gmail.com • 12592 Portada Place • San Diego, CA 92130• (858) 900-8458

EDUCATION
Torrey Pines High School 2015 – Present
Weighted 10-12 GPA: 4.82/4.00
Relevant Coursework: Multivariable Calculus, Linear Algebra, AP Statistics

WORK EXPERIENCE
Research Intern 06/16-08/16
Prof. Thad Kousser
Department of Political Science, UCSD
Worked with machine learning algorithms to analyze mass data on candidate Tweet behavior and its effects on polling status
in the 2016 election.

Research Intern 06/17-08/17


Prof. Michael Sailor
Department of Chemistry & Biochemistry, UCSD
Worked on in vivo biological imaging with luminescent silicon nanoparticles to improve tumor detection. Won best
presentation award.

Research Intern 06/18-Present


Prof. Kyle Gaulton
Department of Pediatrics, UCSD
Used machine learning algorithms to perform multivariate analysis on T1D genomic data. Aimed to discover/cluster novel
risk loci.

EXTRACURRICULAR ACTIVITIES
Robotics Team 03/16 – Present
Head of Outreach (11th) and member of Programming Team. Created outreach programs such as robotics teams at local
schools and raised $5K in funding. Worked with programming team to debug robot code and taught new members Java.

JV/Varsity Academic Team 11/15– Present


JV MVP & Top Scorer and was promoted to Varsity for Playoffs (2018). Inland Varsity champions and 2nd Place at County
Finals (2018).

TEACHING and VOLUNTEERING EXPERIENCE


Assistant for the Algebra Club at Carmel Del Mar Elementary School 09/14 – Present
Gave lectures and graded homework for the club at my former elementary school. Club was aimed at enriching advanced
math students.

Founder of the Machine Learning/Bioinformatics Club 09/18 – Present


Aimed at introducing the basics of machine learning and its applications (bioinformatics specifically) to a beginner audience
using Python.

Private Tutor for Math, English, and Spanish 09/18 – Present


Helped struggling students perform better in their classes by reinforcing topics taught in class and going over examples with
them.

AWARDS and HONORS


Academic Team JV MVP (2018)
Academic Team JV Top Scorer (2018)
Nominated Delegate to Global Leadership Connection (2018)
Inland Varsity Academic Team Champions and Second Place at County Finals (2018)
Second Place Team Honors Statistics Contest (2018)
Semifinalists at FIRST Regional Robotics Competition Las Vegas (2017)
REFERENCES
Mrs. Zakia Chowdhury
AP Calculus Teacher
Torrey Pines High School
3710 Del Mar Heights Rd
San Diego, CA 92130
(858) 755-0125 x2139

Dr. Kyle Gaulton


Assistant Professor of Pediatrics
University of California San Diego
9500 Gilman Dr
La Jolla, CA 92093
858-822-3640
Kyle Gaulton Research Group | University of California San Diego, Department of Pediatrics

Uncovering and characterizing genetic risk mechanisms of Type 1 Diabetes using Multi-Trait Analysis
of GWAS [Manuscript in progress]

Aalipour E1, Chiou J1, Beebe E1, Corban S1, Gaulton K1

1
Department of Pediatrics, University of California San Diego, San Diego, CA, 92093, USA

Abstract:

Type 1 Diabetes (T1D) is a significant global health concern, but its underlying genetic causes remain
poorly understood. In particular, previous efforts to identify susceptible genomic loci have achieved
limited success in describing genetic pathways that are implicated in disease risk. There is thus a
pressing need for strategies that can identify new disease-associated genomic loci in T1D to expand our
mechanistic understanding of the disease.

Disease-associated genomic loci are often found using genome-wide associated studies to find genetic
variants that are present in greater frequency in diseased patients compared to a healthy population, but
one limitation of this approach is that the association analysis is limited to a single disease at a time.
Multi-Trait Analysis of GWAS (MTAG) is a recently described algorithm which can overcome this
limitation by running multivariate analysis of GWAS data from multiple related diseases and thus
greatly increase the statistical power of detecting disease-associated genetic variants for any single
disease. Since patients with T1D often suffer from other related autoimmune comorbidities, in this paper
we apply MTAG analysis for T1D GWAS data along with GWAS data from related autoimmune
diseases including Systemic Lupus Erythematosus and Rheumatoid Arthritis.

After removal of previously identified risk loci for T1D, this technique highlighted 6 novel genomic risk
loci for T1D that have not previously been reported in the literature. We then applied hierarchical
clustering in conjunction with dimension reduction techniques to understand what cellular pathways
these genomic loci are involved in hopes of shedding light on the mechanistic development of T1D.
These studies will potentially have a significant impact on our understanding of the underlying genetic
causes of T1D and therapeutic strategies.