DE LA SALLE HEALTH SCIENCES INSTITUTE

COLLEGE OF MEDICINE
Department of Pharmacology
School Year: 2017 – 2018

CLINICAL PHARMACOLOGY
EVALUATION # 2
July 31, 2017

ANSWER KEY
NAME: ____________________________________________ STUDENT NO. __________

GENERAL DIRECTIONS: Choose the best answer. (65 items)

A. SET 1

COLUMN I COLUMN II ANSWER

(Medication Error)

1. Improper preparation A. Prescribing Error D

2. Prescription of wrong drug B. Transcription Error A

3. Wrong concentration dispensed C. Dispensing Error C

4. Unreadable prescription D. Administration Error A

5. Generic name does not coincide A

with brand name

B. SET 2

COLUMN I COLUMN II ANSWER

6. Data reported to decision makers A. Adulterated medicines D

7. Counterfeit drugs B. May be life-threatening A

8. Effect of medication errors to patients C. Pharmacogivilance B

9. Fear of repercussion D. Feedback loop E

10. Eliminate or minimize drug related E. Failure of Reporting C

adverse effects

C. SET C

PROBLEM ERROR PREVENTION ANSWER

11. Look alike, sound alike drugs A. Read instruction on D

administration

12. Exposure to extremes of temperature B. Observe proper storage B

13. Incomplete patient data C. Maintain proper drug packaging E

14. Exposed drug vials D. Drug Labels should be verified C

15. Confusing drug design E. Make a complete prescription A

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D. SET 4

TASK PERSON RESPONSIBLE ANSWER

16. Call MD for clarifications before dispensing A. Physician B

17. Document medication error data in the B. Pharmacists E

community

18. Increase awareness related to drug use C. Patient E

19. Misuse dangers of non-doctor prescribed medicine C

20. Make drug orders clear and legible A

E. SET 5

COLUMN I COLUMN II ANSWER

21. Pharmaceutical Quality Assurance A. Performance standards set by WHO E

22. Pharmaceutical Quality Control B. Extent of drug absorption by oral dose D

23. Drug Bioavailability C. Absence of contaminants/impurities B

24. Drug Purity D. Process carried out prior to releasing C

medications for public use

25. Good Manufacturing Practices E. Practices to ensure safe, quality and A

effective medicines

Process of Rational Treatment/Rational Prescribing

For numbers 26 – 35, TRUE or FALSE.

26. The process of rational treatment only includes choosing a drug for a particular problem of
the patient. FALSE

27. Medical and therapeutic problem solving starts with the physician's diagnosis. FALSE

28. To serve the patient's problem, the doctor has to choose from several possible treatments.
TRUE

29. The drug of choice to a particular disease should always be the first medication to be started
on the patient. FALSE

30. The cost of treatment is important only in developing countries. FALSE

31. The Onset and duration of symptoms are necessary in determining the patient's problem.
TRUE

32. Safety is the sole criterion in choosing the appropriate drug for a patient. FALSE

33. Non-drug measures are as important as pharmacological interventions. TRUE

34. The In rational prescribing, a drug should be given to every symptom reported by the
patient.. FALSE

35. An inventory of effective drug groups is needed in rational prescribing. TRUE

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For numbers 36 – 45: Match the following scenarios/statements as to the steps in rational
prescribing
A. Defining the patient’s problem
B. Specifying the therapeutic objective
C. Verifying the suitability of the drug treatment
D. Write a prescription
E. Giving information, instructions and warning
F. Monitoring treatment

36. Shifting the prescribed drug to an alternative medication. F

37. Reviewing the drug’s contraindications and interactions. C

38. Done to focus on the problem and to help avoid unnecessary prophylactic prescribing. B

39. Making the right diagnosis. A

40. Checking the drug dosing schedule. C

41. Prescription of clonidine was given to a known hypertensive patient. D

42. Changing the paracetamol schedule to every 6 hours in a nephrotic patient. C

43. Providing leaflets and day calendar to a patient who will start thyroid hormonal replacement
therapy. E

44. Obtaining a pregnancy test before starting treatment with anti-coagulants. C

45. Tapering down of anti-epileptics in an improving patient. F

46. In the treatment of a chronic disease, which among the following should be the maximum
monitoring interval?
a. 2 weeks
b. 4 weeks
c. 3 months
d. 6 months

47. Contraindications of a certain drug are determined by the following:

a. Mechanism of action of the drug itself
b. Other diseases of the patient
c. Characteristics of an individual patient
d. All of the above

48. In considering the dosage schedule, this factor should be increased in order for the drug
plasma concentration to rise:
a. Absorption
b. Distribution
c. Metabolism
d. Excretion

49. To ensure the effectiveness of the treatment, the physician should:

a. Select the most convenient dosage form for the patient
b. Screen whether the patient belongs to high risk groups
c. Obtain a thorough history of other medications taken by the patient
d. Always apply the standard dosage schedule

50. The therapeutic window in the individual patient can be determined by:
a. Careful monitoring
b. Logical thinking
c. Trial
d. All of the above
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PRESCRIPTION WRITING
Instruction: Create a prescription using the appropriate drug for the following cases. (15 points)

CASE 1
KJ., 22-year old female with history of cough for 5 days
PE: not in respiratory distress, (+) crackles on all lung fields
Diagnosis: Pneumonia

MED BANK:
a. Ipratropium bromide nebule 0.5mg/ 2ml; Nebulize 2ml every 8 hours for 3 days (available
in nebules of 0.5mg/ 2ml)
b. Amoxicillin tablet 500mg; Take one tablet every 8 hours, round-the-clock for 7 days
(available in tablets of 500mg)
c. Ibuprofen tablet 500mg; Take one tablet every 6 hours on a full stomach for 5 days
(available in tablets of 500mg)

Kendra Joy, 22/F 31 July 2017

Dasmarinas, Cavite

Rx

[Amoxicillin tablet 500mg]

Dispense No.: [21]
Label: [Take one tablet every 8 hours, round‑the‑clock for 7 days]

SAS
S.A. Santos, MD
Lic: 061016
PTR: 092015

CASE 2

J.M., 10-year old male with history of fever (38.3C) and itchiness all over
PE: (+) vesicular lesions all over the body
Diagnosis: Varicella infection

MED BANK:

a. Amoxicillin Oral Suspension 250mg/5ml; Give 15 ml every 8 hours round-the-clock for

7 days (available in bottles of 60ml)
b. Aciclovir Cream 5%, Apply on affected areas 6 times a day for 10 days. (available in
5g cream)
c. Paracetamol Syrup 250mg/5ml; Give 15 ml every 4 hours round-the-clock for 5 days.
(available in bottles of 60ml)

James Mranz, 10/M 31 July 2017

Dasmarinas, Cavite

Rx

Paracetamol Syrup 250mg/5ml]

Dispense No.: [8]
Label: [Give 15 ml every 4 hours, round‑the‑clock for 5 days]

SAS
S.A. Santos, MD
Lic: 061016
PTR: 092015

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CASE 3

F.Z., 25-year old female with history of pinpoint chest pain

PE: Tenderness at the 2nd ICS, right; Regular heart rate, normal heart sounds, no murmurs
Diagnosis: Costochondritis

MED BANK:

a. Amlodipine besilate tablet 5mg; Take one tablet twice a day for one month. (available in
tablets of 5mg)
b. Mefenamic acid tablet 500mg; Take one tablet every 6 hours on a full stomach for 5 days.
(available in tablets of 500mg)
c. Clopidogrel bisulfate capsule 75mg; Take one capsule once a day on a full stomach for
one month. (available in tablets of 75mg)

Fanny Zoe, 25/F 31 July 2017

Dasmarinas, Cavite

Rx

[Mefenamic Acid Tablet 500mg]

Dispense No.: [20]
Label: [Take one tablet every 6 hours on a full stomach for 5 days]

SAS
S.A. Santos, MD
Lic: 061016
PTR: 092015

------------------ END OF SECOND EVALUATION ------------------

Note: All answers are based on Moodle.

COMPILED BY: Alfonso Martin E. Plantilla, Group 2B2B

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