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Pregnancy

Late preterm birth increases risk of respiratory illness (New Kerala-28 July 2010)

Washington, July 28 - A new research has found that babies born between 34 weeks and 37 weeks
gestation are much more likely to have respiratory illness compared to infants born at full term.

The research was conducted by University of Illinois at Chicago and by researcher Dr. Judith Hibbard and
colleagues from the Consortium on Safe Labor.

"Even at 37 weeks, babies were three times more likely to have respiratory distress syndrome compared to
babies born at 39- or 40 weeks," said Hibbard, UIC professor of obstetrics and gynecology and lead
author of the study.

Data were collected from electronic medical records on 233,844 deliveries at 19 hospitals across the U.S.
between 2002 and 2008.

Hibbard said respiratory illnesses such as RDS, transient tachypnea, pneumonia and respiratory failure
can lead to other problems such as longer hospitalization, the need for a ventilator or antibiotics, and
issues with feeding and failure to gain weight.

Using a statistical model, the researchers examined infant respiratory illnesses at each gestational week,
controlling for factors that influence respiratory outcomes including maternal medical conditions, length
of labor and mode of delivery, and birth weight.

The study found that late preterm births accounted for 9 percent of all deliveries. Thirty-seven percent of
late preterm infants were admitted to the neonatal intensive care unit, compared with 7 percent of term
infants.

RDS was the most common respiratory illness, occurring in 11 percent of 34-week deliveries. Only 0.3
percent of 40-week deliveries had RDS.

Transient tachypnea, also called "wet lungs," was the second most common respiratory illness, occurring
in 6.4 percent of 34-week deliveries, and decreasing to 0.3 percent at 39 weeks.

"The OB community needs to assess indications for induction of labor," said Hibbard, who hopes that this
study will help clinicians to counsel their patients about the importance of not requesting medically
unnecessary inductions.

The study is published in the July 28 issue of JAMA.