c
 

 
 

 
   
  
 


Fluphenazine 25 mg/ml IM Prolixin Decanoate ïÔubcortical ï^PÔ Fluphenazine  
- Arrange for discontinuation
decanoate (Fluphenazine Decanoate Brain Damage (pseudoparkinso markedly
of drug if serum creatinine,
Injection) is a long-acting ïPatients with nism,dystonia, prolongs the
BU` become abnormal or if
parenteral antipsychotic drug high dose dyskinisia, durg¶s
WB count is depressed.
intended for use in the hypnotics akathisia,) duration of
- Monitor elderly patients for
management of patients ïoma or ïŒardive effect without
dehydration, institute
requiring prolonged severe dyskinisia unduly
remedial measures promptly.
parenteral neuroleptic depression ï`euroleptic attenuating its
Ôedation and decreased
therapy (e.g., chronic ïBlood malignant beneficial
sensation of thirst related to
schizophrenics).Prolixin Dec dyscrasia syndrome action. Active
`Ô effects can lead to
anoate has not been shown ïBelow 12y/o ï£ethargy on all `Ô as
severe dehydration.
effective in the management ïºypertension well as on
- onsult physician regarding
of behavioral complications ïItching multiple
appropriate warning of
in patients with mental ï£eucopenia, organs systems
patient or patient's guardian
retardation. agranulocytosis, *mechanism
about tardive dyskinesias.
thrombocytopen whereby its
- onsult physician about
ia therapeutic
dosage reduction, use of
action is
anticholinergic
exerted is
antiparkinsonian drugs
unknown.
(controversial) if
extrapyramidal effects occur.
c
 

 
 

 
   
  
 
 

hlopromazine -Acute and chronic - ºypersensitivity. -`Ô neuroleptic  
PO 10-25mg - Block
2=4 times psychoses, particularly -ross-sensitivity may malignant syndrome, dopamine  c 

daily; may when accompanied by exist among sedation, receptors in - Assess mental status prior
increase every increased psychomotor phenothiazines. Ôhould extrapyramidal the brain; to and periodically during
3-4 days (usual activity. `ausea and not be used in narrow- reactions, tardive also alter therapy.
dose is vomiting. angle glaucoma. dyskinesia dopamine - Monitor BP and pulse
200ng/day; up - Also used in the -Ôhould not be used in -
hypotension release and prior to and frequently
to 1g/day) treatment of intractable patients who have `Ô (increased with IM, turnover. during the period of dosage
PO 10-25mg hiccups. depression. I
) - Prevention adjustment. May cause QŒ
2=4 times -^^`Œ blurred of seizures interval changes on ^G.
daily; may vision, dry eyes, lens - Observe patient carefully
increase every opacities when administering
3-4 days (usual - GI constipation, medication, to ensure that
dose is dry mouth, anorexia, medication is actually
200ng/day; up
hepatitis, ileus taken and not hoarded.
to 1g/day)
- GU urinary -Monitor I&O ratios and
retention daily eight. Assess patient
- ºematologic for signs and symptoms of
agranulocytosis, dehydration.
leukopenia - Monitor for development
- Ôkin of neuroleptic malignant
photosensitivity, syndrome (fever,
pigment changes, respiratory distress,
rashes tachycardia, seizures,
diaphoresis, hypertension
 or hypotension, pallor,
tiredness, severe muscle
stiffness, loss of bladder
control. Report symptoms
immediately. May also
cause leukocytosis,
elevated liver function
tests, elevated PK.
- Advise patient to take
medication as directed.
Œake missed doses as soon
as remembered, witih
remaining doses evenly
spaced through out the day.
May require several weeks
to obtain desired effects.
Do not increase dose or
discontinue medication
without consulting health
care professional. Abrupt
withdrawal may cause
dizziness, nausea,
vomiting, GI upset,
trembling, or uncontrolled
movements of mouth,
tongue or jaw.
c
 

 
 

 
   
  
 
  

Biperiden ºl PO²2 mg; - Adjunct in the therapy - ontraindicated with Adverse effects Anticholiner  
in ÷
 are most - Decrease dosage or
IM²5 mg/m£ of parkinsonism (post- hypersensitivity to gic activity
common; those discontinue temporarily if
encephalitic, benztropine; glaucoma, in 0 are life- in the `Ô dry mouth makes
threatening. swallowing or speaking
arteriosclerotic, and especially angle-closure that is
difficult.
idiopathic types) glaucoma; pyloric or -  Ôome are believed to - Give with caution, and
reduce dosage in hot
- Relief of symptoms of duodenal obstruction, characteristic of help
weather. Drug interferes
extrapyramidal disorders stenosing peptic ulcers, centrally acting normalize with sweating and ability
of body to maintain heat
that accompany achalasia anticholinergic the
equilibrium; anhidrosis and
phenothiazine therapy (megaesophagus); drugs Y

 hypothesize fatal hyperthermia have
occurred.
prostatic hypertrophy or   
memory d imbalance
- Give with meals if GI
bladder neck loss, hallucinations, of upset occurs; give before
meals to patients with dry
obstructions; psychoses, cholinergic
mouth; give after meals if
myasthenia gravis. agitation,    and drooling or nausea occurs.
- ^nsure that patient voids
- Use cautiously with 
delusions, delirium, dopaminergi
just before receiving each
tachycardia, cardiac paranoia, euphoria, c dose of drug if urinary
retention is a problem.
arrhythmias, excitement,   neurotransm
hypertension, 
YY 
 ission in the ! " 
hypotension, hepatic or basal - Œake this drug exactly as
Y 
depression,
renal dysfunction, ganglia in prescribed.
drowsiness,
alcoholism, chronic the brain of - Avoid the use of alcohol,
weakness, giddiness,
illness, people who a sedative, and OŒ drugs
paresthesia,
work in hot parkinsonis (can cause dangerous
heaviness of the
environment; hot m patient. effects).
limbs
weather; lactation. Reduces - Œhese side effects may

severity of occur drowsiness,

rigidity, and dizziness, confusion,

 to a lesser blurred vision (avoid
extent driving or engaging in
akinesia and activities that require
tremor alertness and visual
characterizin acuity); nausea (try
g frequent small meals); dry
parkinsonis mouth (suck sugarless
m; less lozenges or ice chips);
effective painful or difficult
overall than urination (empty the
levodopa; bladder immediately before
peripheral each dose); constipation
anticholiner (maintain adequate fluid
gic effects intake and exercise
suppress regularly); use caution in
secondary hot weather (you are
symptoms of susceptible to heat
parkinsonis prostration).
m, such as - Report difficult or painful
drooling urination; constipation;
rapid or pounding
heartbeat; confusion, eye
pain, or rash.



 
 #


  " $

 " $$    

 
 %



  
c  
&
%  Disturbed Increase in 

   ïDecrease ï Œo decrease After 6days of
ï Inability to Œhought Process dopamine. ï Maintain stimuli in possibility of intervention,
concentrate related to Dopamine is a orientation to environemt having short term goal
ï ºypervigilance biochemical general excitatory time, place ï orrect inaccurate was met and

&
% alterations as hormone and client¶s sensory long term goal
ï ako ang may ari evidenced by circumstance description perceptions was partially
ng World bank´ hypervigilance for period of of inaccurate ï ^xplanations, met. lient was
ï military ako and ditractibility time sensory participations able to update
ngayon, ako ay 1st £
  perception in real his knowledge
private 2nd private ï Demonstrate activities of time, place
sargento general´ a more interferes with and weather
accurate the ability to conditions.
perception of respond to lient also
the haluucinations improved in
environment item
by identification
responding exercises
appropriately
to stimuli
indigenous
to the
surroundings




  " $
 " $$    

 
 %



  
c  
&
%  Disturbed Increase in 

   ïDecrease ï Œo decrease After 6days of
ï Inability to Œhought Process dopamine. ï Maintain stimuli in possibility of intervention,
concentrate related to Dopamine is a orientation to environemt having short term goal
ï ºypervigilance biochemical general excitatory time, place ï orrect inaccurate was met and

&
% alterations as hormone and client¶s sensory long term goal
ï ako ang may ari evidenced by circumstance description perceptions was partially
ng World bank´ hypervigilance for period of of inaccurate ï ^xplanations, met. lient was
ï military ako and ditractibility time sensory participations able to update
ngayon, ako ay 1st £
  perception in real his knowledge
private 2nd private ï Demonstrate activities of time, place
sargento general´ a more interferes with and weather
accurate the ability to conditions.
perception of respond to lient also
the haluucinations improved in
environment item
by identification
responding exercises
appropriately
to stimuli
indigenous
to the
surroundings