Subject Topics Chapter code

• English grammar,
Verbal Ability[ Comes
• sentence completion,
under General Aptitude:
• verbal analogies, • verbal Ability
15 marks has been
• word groups, • Critical
dedicated for General
• instructions, Reasoning
Aptitude(applicable to all
• critical reasoning and
papers)]
• verbal deduction.
Numerical Ability
[Comes under General
• Numerical computation,
Aptitude: 15 marks has • Numerical Ability
• numerical estimation,
been dedicated for • Data
• numerical reasoning and
General Interpretation
• Data interpretation.
Aptitude(applicable to all
papers)]

• M1: Matrices and

determinants,
• M2: Systems of linear
Linear Algebra equations, Linear Algebra
• M3: Eigen values and
Eigen vectors.

• Limit,
• continuity and
differentiability,
• Partial derivatives,
Calculus Calculus
• Maxima and minima,
• Sequences and series,
• Test for convergence,
• Fourier Series
• Linear and nonlinear
first order ODEs,
• higher order ODEs with
constant coefficients,
Differential • Cauchy’s and Euler’s
Differential Equations
Equations: equations,
• Laplace transforms,
• PDE- Laplace,
• heat and wave equations.

Probability and Probability

• Mean, Statistics
Statistics:
 • median, mode and
standard deviation,
• Random variables,
• Poisson, normal and
binomial distributions,
• Correlation and
regression analysis.
• Solution of linear and
nonlinear algebraic
equations,
• Integration of
Numerical Methods trapezoidal and Numerical methods
Simpson’s rule,
• Single and multi step
methods for differential
equations.

• Prokaryotic and BT-MB-1

Prokaryotic and
eukaryotic cell
eukaryotic cell structure;
structure; Microbial diversity and
• Microbial nutrition, characteristic features;
growth and control; Viruses.
• Microbial metabolism
BT-MB-2
(aerobic and anaerobic
Microbial nutrition,
respiration, growth and control;
photosynthesis);Nitrogen Microbial metabolism
fixation; (aerobic and anaerobic
Microbiology: • Chemical basis of respiration,
mutations and mutagens; photosynthesis); Nitrogen
• Microbial genetics fixation
(plasmids, BT-MB-3
transformation, Chemical basis of
transduction, mutations and mutagens;
conjugation); Microbial genetics
• Microbial diversity and (plasmids, transformation,
characteristic features; transduction,
• Viruses. conjugation);

• Biomolecules and their
conformation;
Ramachandran map;
• Weak inter-molecular
interactions in
biomacromolecules;
• Chemical and functional
nature of enzymes;
• Kinetics of single
substrate and bi-
substrate enzyme
catalyzed reactions;
• Bioenergetics;
Biochemistry: Metabolism (Glycolysis,
TCA and Oxidative
phosphorylation);
• Membrane transport and
pumps;
• Cell cycle and cell
growth control;
• Cell signaling and signal
transduction;
• Biochemical and
biophysical techniques
for macromolecular
analysis.
Molecular structure of genes
and chromosomes; DNA
replication and control;
Transcription and its control;
Translational processes;
Molecular Biology
Regulatory controls in
and Genetics
prokaryotes and eukaryotes;
Mendelian inheritance; Gene
interaction; Complementation;
Linkage, recombination and
chromosome mapping;
BT-BC-1
Biomolecules and their
conformation;
Ramachandran map;
Weak inter-molecular
interactions in
biomacromolecules;
BT-BC-2
Chemical and functional
nature of enzymes;
Kinetics of single
substrate and bi-substrate
enzyme catalyzed
reactions;
BT-BC-3
Bioenergetics;
Metabolism (Glycolysis,
TCA and Oxidative
phosphorylation);
Membrane transport and
pumps;
BT-BC-4- Soma
Cell cycle and cell growth
control; Cell signaling
and signal transduction;
BT-BC-5- Soma
Biochemical and
biophysical techniques
for macromolecular
analysis.
BT-MbG-1
Molecular structure of
genes and chromosomes;
BT-MbG-2
DNA replication and
control; Transcription and
its control; Translational
processes; Regulatory
controls in prokaryotes
and eukaryotes;
BT-MbG-3
 Mendelian inheritance;
Gene interaction;
Extrachromosomal
inheritance;

BT-MbG-4
Complementation;
Extrachromosomal inheritance; Linkage, recombination
Chromosomal variation; and chromosome
Population genetics; mapping;
Transposable elements,
BT-MbG-5
Molecular basis of genetic Population genetics;
diseases and applications.
BT-MbG-6
Chromosomal
variation;Transposable
elements, Molecular basis
of genetic diseases and
applications.

Bioprocess technology for the
production of cell biomass and
primary/secondary metabolites,
such as baker’s yeast, ethanol,
citric acid, amino acids, exo-
polysacharides, antibiotics and
pigments etc.; Microbial
production, purification and
bioprocess application(s) of
industrial enzymes; Production
Process
and purification of recombinant
Biotechnology:
proteins on a large scale;
Chromatographic and
membrane based bioseparation
methods; Immobilization of
enzymes and cells and their
application for bioconversion
processes. Aerobic and
anaerobic biological processes
for stabilization of solid / liquid
wastes; Bioremediation.
BT-PB-1
Bioprocess technology
for the production of cell
biomass and primary/
secondary metabolites,
such as baker’s yeast,
ethanol, citric acid, amino
acids, exo-polysacharides,
antibiotics and pigments
etc.;
BT-PB-2
Microbial production,
purification and
bioprocess application(s)
of industrial enzymes;
Production and
purification of
recombinant proteins on a
large scale;
BT-PB-3
Chromatographic and
membrane based
bioseparation methods;

Kinetics of microbial growth,
substrate utilization and product
formation; Simple structured
models; Sterilization of air and
media; Batch, fed-batch and
continuous processes; Aeration
and agitation; Mass transfer in
Bioprocess
bioreactors; Rheology of
Engineering
fermentation fluids; Scale-up
concepts; Design of
fermentation media; Various
types of microbial and enzyme
reactors; Instrumentation in
bioreactors.
Special features and
organization of plant cells;
Plant and Animal
Totipotency; Regeneration of
Biotechnology
plants; Plant products of
industrial importance;
BT-PB-4
Immobilization of
enzymes and cells and
their application for
bioconversion processes.
BT-PB-5
Aerobic and anaerobic
biological processes for
stabilization of solid /
liquid wastes;
Bioremediation.
BT-BpE-1
Kinetics of microbial
growth, substrate
utilization and product
formation;Simple
structured models;
BT-BpE-2
Sterilization of air and
media; Batch, fed-batch
and continuous processes;
Aeration and agitation;
Mass transfer in
bioreactors;
BT-BpE-3
Rheology of fermentation
fluids; Scale-up concepts;
Design of fermentation
media;
BT-BpE-4
Various types of
microbial and enzyme
reactors; Instrumentation
in bioreactors.
BT-Pabt-1
Special features and
organization of plant
cells; Totipotency;
Regeneration of plants;
BT-PaBt-2

Biochemistry of major
metabolic pathways and
products; Autotrophic and
heterotrophic growth; Plant
growth regulators and elicitors;
Cell suspension culture
development: methodology,
kinetics of growth and
production formation, nutrient
optimization; Production of
secondary metabolites by plant
suspension cultures; Hairy root
cultures and their cultivation.
Techniques in raising
transgencies.
Metabolism, regulation and
nutritional requirements for
mass cultivation of animal cell
cultures; Kinetics of cell growth
and product formation and
effect of shear force; Product
Characteristics of and substrate transport; Micro
animal cells: & macro-carrier culture;
Hybridoma technology; Live
stock improvement; Cloning in
animals; Genetic engineering in
animal cell culture; Animal cell
preservation.
Plant products of
industrial importance;
Biochemistry of major
metabolic pathways and
products; Autotrophic and
heterotrophic growth;
BT-PaBT-3
Plant growth regulators
and elicitors; Cell
suspension culture
development:
methodology,
BT-PaBT-4
kinetics of growth and
production formation,
nutrient optimization;
Production of secondary
metabolites by plant
suspension cultures;
BT-PaBT-5
Hairy root cultures and
their cultivation.
Techniques in raising
transgencies.
BT-Ac-1
Metabolism, regulation
and nutritional
requirements for mass
cultivation of animal cell
cultures; Kinetics of cell
growth and product
formation and effect of
shear force;
BT-Ac-2
Product and substrate
transport; Micro &
macro-carrier culture;
BT-Ac-3
Hybridoma technology;
Live stock improvement;

The origin of immunology;
Inherent immunity; Humoral
and cell mediated immunity;
Primary and secondary
lymphoid organ; Antigen; B
and T cells and Macrophages;
Major histocompatibility
complex (MHC); Antigen
processing and presentation;
Synthesis of antibody and
Immunology:
secretion; Molecular basis of
antibody diversity; Polyclonal
and monoclonal antibody;
Complement; Antigen-antibody
reaction; Regulation of immune
response; Immune tolerance;
Hyper sensitivity;
Autoimmunity; Graft versus
host reaction.
Recombinant DNA Restriction and modification
Technology enzymes; Vectors: plasmid,
Cloning in animals;
Genetic engineering in
animal cell culture;
Animal cell preservation.
BT-I-1
The origin of
immunology; Inherent
immunity; Humoral and
cell mediated immunity;
BT-I-2
Primary and secondary
lymphoid organ; Antigen;
B and T cells and
Macrophages; Major
histocompatibility
complex (MHC);
BT-I-3
Antigen processing and
presentation; Synthesis of
antibody and secretion;
Molecular basis of
antibody diversity;
BT-I-4
Polyclonal and
monoclonal antibody;
Complement; Antigen-
antibody reaction;
Regulation of immune
response; Immune
tolerance;
BT-I-5
Hyper sensitivity;
Autoimmunity; Graft
versus host reaction.
BT-GE-1
Restriction and
modification enzymes;

bacteriophage and other viral
vectors, cosmids, Ti plasmid,
yeast artificial chromosome;
cDNA and genomic DNA
library; Gene isolation; Gene
cloning; Expression of cloned
gene; Transposons and gene
targeting; DNA labeling; DNA
sequencing; Polymerase chain
reactions; DNA fingerprinting;
Southern and northern blotting;
In-situ hybridization; RAPD;
RFLP; Site-directed
mutagenesis; Gene transfer
technologies; Gene therapy.
Major bioinformatics
resources (NCBI, EBI,
ExPASy); Sequence and
structure databases;
Sequence analysis
Bioinformatics (biomolecular sequence
file formats, scoring
matrices, sequence
alignment, phylogeny);
Genomics and
Proteomics (Large scale
Vectors: plasmid,
bacteriophage and other
viral vectors, cosmids, Ti
plasmid, yeast artificial
chromosome;
BT-GE-2
cDNA and genomic DNA
library; Gene isolation;
Gene cloning; Expression
of cloned gene;
BT-GE-3
Transposons and gene
targeting; DNA labeling;
DNA sequencing;
Polymerase chain
reactions; DNA
fingerprinting;
BT-GE-4
Southern and northern
blotting; In-situ
hybridization; RAPD;
RFLP; Site-directed
mutagenesis;
BT-GE-5
Gene transfer
technologies; Gene
therapy.
BT-Bioinfo-1
Major bioinformatics
resources (NCBI, EBI,
ExPASy); Sequence and
structure databases;
BT-Binfo-2
Sequence analysis
(biomolecular sequence
file formats, scoring
matrices, sequence
alignment, phylogeny);
 BT-Bioinfo-3
Genomics and Proteomics
genome sequencing (Large scale genome
strategies; Comparative sequencing strategies;
genomics; Understanding Comparative genomics;
DNA microarrays and BT-Bioinfo-4
protein arrays); Understanding DNA
Molecular modeling and microarrays and protein
simulations (basic arrays); Molecular
concepts including modeling and simulations
(basic concepts including
concept of force fields).
concept of force fields).